CAS No. 247257-48-3

Batch: Purity:99.75
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Fimasartan Chemical Structure
Chemical Structure
Check the Fimasartan product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 247257-48-3
Molecular Formula

C27H31N7OS
Molecular Weight (MW) 501.65
SMILES CCCCC1=NC(=C(C(=O)N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CC(=S)N(C)C)C

Ordering Information

Biological Activity

Fimasartan is a non-peptide angiotensin II type 1 (AT1) receptor antagonist that exhibits potent, insurmountable blockade of AT1 receptor signaling. By selectively inhibiting AT1 receptor activation, it blocks angiotensin II-mediated downstream pathways, suppressing vasoconstriction, vascular smooth muscle cell proliferation, and oxidative stress in cardiovascular tissues. Consequently, Fimasartan attenuates vascular remodeling and regulates arterial tone.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (199.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 24 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.