Everolimus (RAD001) has been evaluated in numerous Phase 1 through Phase 4 clinical trials supported by pharmaceutical corporations such as Novartis and Pfizer alongside academic centers like Nationwide Children's Hospital. Spanning active, recruiting, and completed statuses, these studies target malignancies including high-grade gliomas, metastatic breast cancer, head and neck carcinomas, and renal cell carcinoma, alongside non-oncological settings like renal transplantation and coronary artery disease. This comprehensive evaluation highlights the drug's extensive therapeutic versatility across oncology, organ transplantation, and cardiovascular medicine.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT05725200 | RECRUITING | Metastatic Colorectal Cancer |
Oslo University Hospital |
2022-09-27 | PHASE2 |
| NCT06942156 | NOT_YET_RECRUITING | Heart Transplant |
Chong Kun Dang Pharmaceutical |
2025-08-14 | PHASE4 |
| NCT07477548 | NOT_YET_RECRUITING | Vascular Malformations; Arteriovenous Malformations; Venous Malformation; Lymphangioma; Nevus, Port-Wine; Hemangioendothelioma; Hemangioma |
Yonsei University |
2026-04-01 | PHASE2 |
| NCT05933395 | RECRUITING | Advanced Breast Cancer |
Dartmouth-Hitchcock Medical Center |
2024-09-23 | PHASE2 |
| NCT07218575 | NOT_YET_RECRUITING | Cowden's Disease; Cowden's Syndrome; Lhermitte-Duclos Disease; Cerebellum Dysplastic Gangliocytoma; Bannayan Zonana Syndrome; Myhre Riley Smith Syndrome; Riley Smith Syndrome; PTEN Hamartoma Tumor Syndrome; Bannayan Riley Ruvalcaba Syndrome |
Boston Children's Hospital |
2026-09-01 | PHASE2; PHASE3 |
| NCT06832189 | RECRUITING | Liver Transplant |
National Institute of Allergy and Infectious Diseases (NIAID) |
2026-01-21 | PHASE1 |
| NCT05843253 | RECRUITING | High Grade Glioma; Diffuse Intrinsic Pontine Glioma; Anaplastic Astrocytoma; Glioblastoma; Glioblastoma Multiforme; Diffuse Midline Glioma, H3 K27M-Mutant; Metastatic Brain Tumor; WHO Grade III Glioma; WHO Grade IV Glioma; Diffuse Hemispheric Glioma, H3 G34-Mutant |
Nationwide Children's Hospital |
2024-08-22 | PHASE2 |
| NCT06943755 | RECRUITING | Pancreatic Neuroendocrine Tumor (pNET); Extra-Pancreatic Neuroendocrine Tumor (epNET) |
Exelixis |
2025-07-21 | PHASE2; PHASE3 |
| NCT04803318 | RECRUITING | Solid Tumor, Adult; Hepatocellular Carcinoma |
Second Affiliated Hospital of Guangzhou Medical University |
2021-01-01 | PHASE2 |
| NCT04199026 | RECRUITING | Metastatic Sarcoma; Recurrent Sarcoma; Resectable Sarcoma |
M.D. Anderson Cancer Center |
2025-02-25 | |
| NCT07619950 | NOT_YET_RECRUITING | Neoplasms of Bone and Articular Cartilage With Unspecified Anatomical Site |
Yonsei University |
2026-07-01 | PHASE2 |
| NCT07760844 | NOT_YET_RECRUITING | Breast Cancer; Triple Negative Breast Cancer (TNBC) |
Fudan University |
2026-10-01 | PHASE3 |
| NCT05476939 | RECRUITING | Diffuse Intrinsic Pontine Glioma; Diffuse Midline Glioma, H3 K27M-Mutant; Diffuse Midline Glioma, H3K27-altered |
Gustave Roussy, Cancer Campus, Grand Paris |
2022-09-29 | PHASE3 |
| NCT07144150 | RECRUITING | Peripheral Vascular Disease; Peripheral Arterial Disease |
Cook Research Incorporated |
2026-04-17 | |
| NCT06680921 | ACTIVE_NOT_RECRUITING | Locally Advanced or Metastatic Breast Cancer |
Jiangsu Simcere Pharmaceutical Co., Ltd. |
2024-11-14 | PHASE3 |
| NCT07165886 | RECRUITING | Gastroenteropancreatic Neuroendocrine Tumors |
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. |
2025-08-29 | PHASE2; PHASE3 |
| NCT06692140 | RECRUITING | Ischemia, Myocardial; Coronary Artery Disease; Percutaneous Coronary Intervention (PCI) |
Odense University Hospital |
2024-11-16 | |
| NCT06280950 | RECRUITING | Liver Transplant |
National Institute of Allergy and Infectious Diseases (NIAID) |
2024-09-12 | PHASE2 |
| NCT07002177 | RECRUITING | Metastatic Breast Cancer; Breast Cancer Stage I; Breast Cancer Stage II; Locally Advanced Breast Cancer (LABC); ER+ Breast Cancer |
Forward Pharmaceuticals Co., Ltd. |
2025-06-01 | PHASE1; PHASE2 |
| NCT05573126 | RECRUITING | Hormone Receptor-positive Breast Cancer; Hormone Receptor Positive HER-2 Negative Breast Cancer; Metastatic Breast Cancer |
Ellipses Pharma |
2023-01-11 | PHASE1; PHASE2 |
| NCT05508906 | RECRUITING | Metastatic Breast Cancer; ER-positive Breast Cancer; HER2-negative Breast Cancer; Breast Cancer; Locally Advanced Breast Cancer |
Olema Pharmaceuticals, Inc. |
2022-08-31 | PHASE1 |
| NCT04542733 | ACTIVE_NOT_RECRUITING | Kidney Transplant Infection; BK Virus Infection |
King Chulalongkorn Memorial Hospital |
2023-06-15 | |
| NCT03955172 | RECRUITING | Kidney Transplant Failure and Rejection |
Hospices Civils de Lyon |
2020-12-03 | |
| NCT07062965 | RECRUITING | Breast Cancer |
Pfizer |
2025-08-05 | PHASE3 |
| NCT07566091 | NOT_YET_RECRUITING | Coronary Artery Disease |
Jung-min Ahn |
2026-06-15 | |
| NCT01141309 | ACTIVE_NOT_RECRUITING | Thyroid Cancer |
Memorial Sloan Kettering Cancer Center |
2010-06 | PHASE2 |
| NCT04919226 | ACTIVE_NOT_RECRUITING | Neuroendocrine Tumors |
ITM Solucin GmbH |
2021-12-21 | PHASE3 |
| NCT02321501 | ACTIVE_NOT_RECRUITING | ALK Positive; Locally Advanced Malignant Solid Neoplasm; Metastatic Malignant Solid Neoplasm; ROS1 Gene Rearrangement; Stage IIIB Lung Non-Small Cell Cancer AJCC v7; Stage IV Lung Non-Small Cell Cancer AJCC v7 |
M.D. Anderson Cancer Center |
2016-06-22 | PHASE1 |
| NCT05563220 | ACTIVE_NOT_RECRUITING | Breast Cancer; Metastatic Breast Cancer |
Stemline Therapeutics, Inc. |
2023-01-24 | PHASE1; PHASE2 |
| NCT07095933 | RECRUITING | Epilepsy; Drug Resistant |
Xuanwu Hospital, Beijing |
2026-07-01 | EARLY_PHASE1 |
| NCT03114527 | ACTIVE_NOT_RECRUITING | Soft Tissue Sarcoma |
Fox Chase Cancer Center |
2017-08-08 | PHASE2 |
| NCT05252585 | ACTIVE_NOT_RECRUITING | Renal Angiomyolipoma |
Novartis Pharmaceuticals |
2023-05-01 | PHASE4 |
| NCT03458221 | RECRUITING | Recurrent Ovarian Cancer; Signal Transduction Pathway Deregulation; Therapy-Associated Cancer |
Gynaecologisch Oncologisch Centrum Zuid |
2023-01-31 | PHASE2; PHASE3 |
| NCT02397083 | ACTIVE_NOT_RECRUITING | Atypical Endometrial Hyperplasia; FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma; FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma |
M.D. Anderson Cancer Center |
2015-09-23 | PHASE2 |
| NCT04893291 | ACTIVE_NOT_RECRUITING | Coronary Artery Disease; Coronary Artery Stenosis |
Fondazione Ricerca e Innovazione Cardiovascolare ETS |
2021-11-16 | |
| NCT01087554 | ACTIVE_NOT_RECRUITING | Advanced Cancer |
M.D. Anderson Cancer Center |
2010-03 | PHASE1 |
| NCT05983107 | RECRUITING | HR+/HER2- Advanced Breast Cancer; Targeted Therapy |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2023-07-20 | PHASE2 |
| NCT06214819 | ACTIVE_NOT_RECRUITING | Coronary Artery Disease |
Fundación EPIC |
2024-03-20 | |
| NCT05949541 | RECRUITING | Breast Cancer; Advanced Breast Cancer |
Fudan University |
2023-07-26 | PHASE2 |
| NCT05835999 | COMPLETED | Aging; Insulin Resistance |
University of Wisconsin, Madison |
2023-03-24 | PHASE2 |
| NCT05188118 | COMPLETED | Renal Cell Carcinoma |
Icahn School of Medicine at Mount Sinai |
2023-02-15 | EARLY_PHASE1 |
| NCT06472388 | RECRUITING | Neuroendocrine Tumors; Progression; Neuroendocrine Tumor Grade 1; Neuroendocrine Tumor Grade 2; Neuroendocrine Tumor of Pancreas; Neuroendocrine Tumor of the Lung; Neuroendocrine Tumor Carcinoid |
AC Camargo Cancer Center |
2024-04-24 | PHASE2 |
| NCT06301386 | NOT_YET_RECRUITING | Colon Cancer |
Fudan University |
2024-04-01 | PHASE2 |
| NCT06126588 | RECRUITING | Meningioma |
Central Hospital, Nancy, France |
2024-11-29 | PHASE2 |
| NCT05594095 | RECRUITING | Breast Neoplasm; Breast Cancer; Hormone Receptor Positive Tumor; HER2-negative Breast Cancer; Advanced Breast Cancer |
Fudan University |
2022-12-30 | PHASE2 |
| NCT05153668 | COMPLETED | Idiopathic Subglottic Tracheal Stenosis |
Johns Hopkins University |
2022-09-30 | EARLY_PHASE1 |
| NCT03632317 | WITHDRAWN | Glioma; Diffuse Intrinsic Pontine Glioma |
University of Michigan Rogel Cancer Center |
2019-10 | PHASE2 |
| NCT05954442 | UNKNOWN | Triple Negative Breast Cancer; Metastatic Breast Cancer; Mutation |
Fudan University |
2023-09-13 | PHASE3 |
| NCT04893785 | RECRUITING | Lung Neuroendocrine Neoplasm; GEP Neuroendocrine Tumor |
National Cancer Institute, Naples |
2021-06-15 | PHASE2 |
| NCT06177808 | UNKNOWN | Coronary Artery Disease |
Soonchunhyang University Hospital |
2024-01-01 | |
| NCT05293964 | ACTIVE_NOT_RECRUITING | Breast Cancer |
Jiangsu Simcere Pharmaceutical Co., Ltd. |
2022-05-18 | PHASE1 |
| NCT05833815 | UNKNOWN | Gallbladder Cancer |
Banaras Hindu University |
2022-11-01 | PHASE2; PHASE3 |
| NCT05206084 | ACTIVE_NOT_RECRUITING | Coronary Artery Disease |
Biotyx Medical (Shenzhen) Co., Ltd. |
2022-03-10 | |
| NCT06482086 | RECRUITING | Locally Advanced Thyroid Gland Carcinoma |
West China Hospital |
2021-06-01 | PHASE2 |
| NCT04591431 | UNKNOWN | Breast Cancer; Gastrointestinal Cancer; Non Small Cell Lung Cancer; Other Cancer |
Fondazione per la Medicina Personalizzata |
2020-10-07 | PHASE2 |
| NCT06769217 | COMPLETED | Coronary Arterial Disease (CAD) |
Frisch Medical Device Private Limited |
2023-01-01 | PHASE4 |
| NCT03216967 | COMPLETED | BK Virus Nephropathy After Kidney Transplantation |
University Hospital, Strasbourg, France |
2018-01-15 | PHASE4 |
| NCT06584773 | UNKNOWN | Disorder Related to Renal Transplantation |
University of Sao Paulo General Hospital |
2015-06 | PHASE4 |
| NCT03440801 | COMPLETED | STEMI - ST Elevation Myocardial Infarction |
Tokorozawa Heart Center |
2017-07-03 | |
| NCT05843253 | Not yet recruiting | High Grade Glioma|Diffuse Intrinsic Pontine Glioma|Anaplastic Astrocytoma|Glioblastoma|Glioblastoma Multiforme|Diffuse Midline Glioma H3 K27M-Mutant|Metastatic Brain Tumor|WHO Grade III Glioma|WHO Grade IV Glioma |
Nationwide Children''s Hospital|Novartis |
2024-05-30 | Phase 2 |
| NCT05079360 | WITHDRAWN | Metastatic Breast Cancer |
Veru Inc. |
2023-03-15 | PHASE2 |
| NCT05429684 | UNKNOWN | HER2+ Breast Cancer |
First Affiliated Hospital Xi'an Jiaotong University |
2021-01-01 | PHASE3 |
| NCT01345136 | TERMINATED | Neurofibromatosis Type 2; Neuroma, Acoustic |
Jonsson Comprehensive Cancer Center |
2015-07-01 | PHASE2 |
| NCT03070301 | COMPLETED | Neuroendocrine Tumors |
Memorial Sloan Kettering Cancer Center |
2017-02-27 | PHASE2 |
| NCT04185831 | UNKNOWN | Solid Tumor |
Uppsala University Hospital |
2020-10-20 | PHASE2 |
| NCT02338609 | COMPLETED | Growth and Development |
Novartis Pharmaceuticals |
2014-12-17 | PHASE4 |
| NCT04236609 | UNKNOWN | Diabetes; Coronary Artery Disease; Acute Coronary Syndrome |
Concept Medical Inc. |
2020-06-15 | |
| NCT05065411 | TERMINATED | Metastatic Breast Cancer |
Veru Inc. |
2022-04-11 | PHASE3 |
| NCT04203901 | TERMINATED | Advanced Renal Cell Carcinoma |
CoImmune |
2020-07-22 | PHASE2 |
| NCT03324373 | COMPLETED | Renal Cell Carcinoma |
Yousef Zakharia |
2019-03-20 | PHASE1 |
| NCT05734157 | COMPLETED | Femoral Artery Stenosis; Popliteal Artery Stenosis; Femoral Artery Occlusion; Popliteal Artery Occlusion |
Abbott Medical Devices |
2022-02-17 | |
| NCT04818632 | COMPLETED | ER+, HER2-, Metastatic Breast Cancer |
AstraZeneca |
2021-11-12 | PHASE1 |
| NCT02711826 | COMPLETED | Kidney Transplant; Adult Living Donor Kidney Transplant Recipients; Renal Transplant; Living Kidney Donor |
National Institute of Allergy and Infectious Diseases (NIAID) |
2016-09-20 | PHASE1; PHASE2 |
| NCT02155920 | COMPLETED | Recurrent Childhood Ependymoma |
University of Texas Southwestern Medical Center |
2015-02 | PHASE2 |
| NCT01120249 | COMPLETED | Kidney Cancer |
SWOG Cancer Research Network |
2011-04-01 | PHASE3 |
| NCT04339062 | COMPLETED | Cutaneous Squamous Cell Carcinoma; Advanced Cancer |
Dana-Farber Cancer Institute |
2020-11-03 | PHASE1; PHASE2 |
| NCT04395989 | UNKNOWN | TNBC - Triple-Negative Breast Cancer |
Fudan University |
2020-07-28 | PHASE2 |
| NCT03386539 | COMPLETED | Pediatric Heart Transplantation; Immunosuppression; Chronic Kidney Diseases; Cardiac Allograft Vasculopathy; Heart Transplant Failure and Rejection; Post-transplant Lymphoproliferative Disorder; Heart Transplant Infection |
Boston Children's Hospital |
2018-01-29 | PHASE3 |
| NCT04192760 | UNKNOWN | Coronary Stenosis; Stent Stenosis |
University Heart Center Freiburg - Bad Krozingen |
2019-12-01 | |
| NCT03654040 | TERMINATED | Liver Transplant |
National Institute of Allergy and Infectious Diseases (NIAID) |
2021-04-22 | PHASE1; PHASE2 |
| NCT03580239 | UNKNOWN | Prostate Cancer |
Tianjin Medical University Second Hospital |
2019-01-01 | PHASE3 |
| NCT05613166 | UNKNOWN | Epilepsy |
National Institute on Drug Dependence, China |
2022-11 | PHASE2 |
| NCT02229136 | COMPLETED | Stomatitis; Oral Mucositis; Neoplasm of the Breast; Malignant Tumor of Breast |
US Oncology Research |
2014-09-04 | PHASE2 |
| NCT05516446 | UNKNOWN | Percutaneous Coronary Intervention (PCI); Coronary Artery Disease (CAD); De Novo Stenosis |
General Administration of Military Health, Tunisia |
2021-08-25 | |
| NCT03245151 | COMPLETED | Recurrent and Refractory Solid Tumors |
Eisai Inc. |
2017-11-16 | PHASE1; PHASE2 |
| NCT05731700 | COMPLETED | In-stent Restenosis |
Abbott Medical Devices |
2021-10-20 | |
| NCT05501769 | Active not recruiting | Breast Cancer |
Arvinas Estrogen Receptor Inc.|Pfizer|Arvinas Inc. |
2022-09-08 | Phase 1 |
| NCT05476939 | Recruiting | Diffuse Intrinsic Pontine Glioma|Diffuse Midline Glioma H3 K27M-Mutant |
Gustave Roussy Cancer Campus Grand Paris|Chimerix|Innovative Therapies For Children with Cancer Consortium |
2022-09-29 | Phase 3 |
| NCT03139747 | SUSPENDED | Thyroid Cancer |
Thomas Jefferson University |
2017-04-03 | PHASE2 |
| NCT02854618 | UNKNOWN | Breast Cancer |
Centre Hospitalier Universitaire de Besancon |
2015-11-26 | |
| NCT05293964 | Recruiting | Breast Cancer |
Jiangsu Simcere Pharmaceutical Co. Ltd. |
2022-05-18 | Phase 1 |
| NCT03312738 | COMPLETED | Advanced Breast Cancer |
Novartis Pharmaceuticals |
2017-09-15 | PHASE2 |
| NCT02173379 | COMPLETED | Coronary Artery Disease; Coronary Artery Stenosis; Coronary Disease; Coronary Stenosis |
Abbott Medical Devices |
2014-07 | |
| NCT03447379 | COMPLETED | Coronary Artery Disease |
Gangnam Severance Hospital |
2017-12-15 | |
| NCT02890069 | COMPLETED | Colorectal Cancer, Non-small Cell Lung Carcinoma (Adenocarcinoma), Triple Negative Breast Cancer, Renal Cell Carcinoma |
Novartis Pharmaceuticals |
2016-10-14 | PHASE1 |
| NCT05490095 | COMPLETED | Pharmacokinetics |
Sovargen |
2021-07-23 | PHASE1 |
| NCT02216786 | COMPLETED | Estrogen Receptor Positive Breast Cancer |
Queen Mary University of London |
2014-01-16 | PHASE2 |
| NCT00805129 | COMPLETED | Bladder Cancer; Metastatic Transitional Cell Carcinoma |
Memorial Sloan Kettering Cancer Center |
2008-12-05 | PHASE2 |
| NCT03721614 | UNKNOWN | Coronary Artery Disease |
Meril Life Sciences Pvt. Ltd. |
2019-09-15 | |
| NCT02638428 | UNKNOWN | Relapsed Pediatric Solid Tumor; Refractory Pediatric Solid Tumor; Relapsed Pediatric AML; Refractory Pediatric AML |
Samsung Medical Center |
2015-12 | PHASE2 |
| NCT02909335 | WITHDRAWN | Liver Transplantation |
Rennes University Hospital |
2016-11 | PHASE3 |
| NCT03659136 | COMPLETED | Breast Neoplasms |
Boehringer Ingelheim |
2018-11-28 | PHASE2 |
| NCT01642186 | COMPLETED | Fibrolamellar Carcinoma; Fibrolamellar Liver Cancer |
Memorial Sloan Kettering Cancer Center |
2012-07-12 | PHASE2 |
| NCT02028364 | COMPLETED | Breast Cancer |
Jules Bordet Institute |
2014-01-12 | PHASE2 |
| NCT02106507 | COMPLETED | Prostate Cancer |
Memorial Sloan Kettering Cancer Center |
2014-04 | PHASE1 |
| NCT02125084 | COMPLETED | Prostate Cancer |
SCRI Development Innovations, LLC |
2014-10 | PHASE1 |
| NCT02387099 | COMPLETED | Breast Cancer; Hormone Receptor Positive Tumor |
GBG Forschungs GmbH |
2015-05 | PHASE2 |
| NCT03154281 | COMPLETED | Breast Cancer; Ovarian Cancer |
Avera McKennan Hospital & University Health Center |
2017-07-26 | PHASE1 |
| NCT02695459 | UNKNOWN | Neuroendocrine Carcinomas |
The Netherlands Cancer Institute |
2016-03-30 | PHASE2 |
| NCT02057133 | ACTIVE_NOT_RECRUITING | Breast Neoplasms |
Eli Lilly and Company |
2014-03-10 | PHASE1 |
| NCT02236572 | TERMINATED | Breast Cancer |
Yale University |
2014-11-29 | PHASE2 |
| NCT02736227 | COMPLETED | Liver Transplantation |
Northwestern University |
2016-03 | |
| NCT01624766 | COMPLETED | Advanced Malignant Neoplasm; Metastatic Malignant Neoplasm; Recurrent Malignant Neoplasm; Refractory Malignant Neoplasm |
M.D. Anderson Cancer Center |
2012-06-19 | PHASE1 |
| NCT02143726 | ACTIVE_NOT_RECRUITING | Refractory Hurthle Cell Thyroid Cancer |
Alliance for Clinical Trials in Oncology |
2014-10-09 | PHASE2 |
| NCT02269670 | TERMINATED | Estrogen Receptor-positive Breast Cancer; HER2-negative Breast Cancer; Progesterone Receptor-positive Breast Cancer; Recurrent Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer |
Emory University |
2014-11-25 | PHASE2 |
| NCT03839940 | TERMINATED | Malignant Neoplasm |
Alliance for Clinical Trials in Oncology |
2019-06-03 | PHASE3 |
| NCT02109913 | UNKNOWN | Hormone Receptor Positive Malignant Neoplasm of Breast; Metastatic Breast Cancer |
Amsterdam UMC, location VUmc |
2014-03 | |
| NCT01399918 | COMPLETED | Renal Cell Carcinoma |
Memorial Sloan Kettering Cancer Center |
2011-07 | PHASE2 |
| NCT02871791 | COMPLETED | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast; Hormone Receptor (HR)-Positive Breast Cancer |
Dana-Farber Cancer Institute |
2016-08-24 | PHASE1; PHASE2 |
| NCT03454724 | UNKNOWN | Coronary Artery Disease |
Meril Life Sciences Pvt. Ltd. |
2020-01-01 | |
| NCT02098876 | COMPLETED | Coronary Artery Disease |
Emory University |
2014-05 | |
| NCT01434602 | COMPLETED | Brain Tumor; Glioblastoma; Anaplastic Glioma |
National Cancer Institute (NCI) |
2012-10-02 | PHASE1; PHASE2 |
| NCT03525834 | COMPLETED | Renal Angiomyolipoma |
Novartis Pharmaceuticals |
2018-11-09 | PHASE4 |
| NCT01789281 | COMPLETED | Neoplasms |
Novartis Pharmaceuticals |
2013-05-14 | PHASE4 |
| NCT01935128 | COMPLETED | Renal Transplant |
University of Toledo Health Science Campus |
2013-07-03 | PHASE4 |
| NCT04188548 | ACTIVE_NOT_RECRUITING | Breast Cancer; Advanced Breast Cancer; Metastatic Breast Cancer; Endometrial Cancer |
Eli Lilly and Company |
2019-12-10 | PHASE1 |
| NCT04258423 | TERMINATED | Kidney Failure |
Indiana University |
2019-12-19 | PHASE3 |
| NCT02138929 | COMPLETED | Esophageal Cancer |
M.D. Anderson Cancer Center |
2014-11-10 | PHASE1 |
| NCT01805271 | ACTIVE_NOT_RECRUITING | Primary Non-metastatic Breast Cancer; Who Remain Disease-free |
UNICANCER |
2013-03 | PHASE3 |
| NCT03726892 | UNKNOWN | Coronary Artery Disease |
Iwate Medical University |
2018-11-12 | |
| NCT01430572 | COMPLETED | Advanced Cancers; Solid Tumors |
M.D. Anderson Cancer Center |
2011-10-07 | PHASE1 |
| NCT03112603 | COMPLETED | Graft-versus-host Disease (GVHD) |
Incyte Corporation |
2017-06-29 | PHASE3 |
| NCT03112707 | UNKNOWN | Coronary Artery Disease; Acute Coronary Syndrome |
Humanitas Hospital, Italy |
2017-04-14 | PHASE4 |
| NCT03387020 | COMPLETED | CNS Embryonal Tumor, Not Otherwise Specified; Malignant Glioma; Recurrent Atypical Teratoid/Rhabdoid Tumor; Recurrent Childhood Ependymoma; Recurrent Diffuse Intrinsic Pontine Glioma; Recurrent Medulloblastoma; Refractory Diffuse Intrinsic Pontine Glioma |
Pediatric Brain Tumor Consortium |
2018-01-13 | PHASE1 |
| NCT03173560 | COMPLETED | Renal Cell Carcinoma |
Eisai Inc. |
2017-08-17 | PHASE2 |
| NCT01563354 | COMPLETED | Neuroendocrine Carcinoma of the Lung and Thymus |
Novartis Pharmaceuticals |
2013-08-16 | PHASE2 |
| NCT02724020 | COMPLETED | Clear-cell Metastatic Renal Cell Carcinoma |
Millennium Pharmaceuticals, Inc. |
2016-06-30 | PHASE2 |
| NCT01734512 | COMPLETED | Pediatric Recurrent Progressive Low-grade Gliomas; Pediatric Progressive Low-grade Gliomas |
University of California, San Francisco |
2012-12-13 | PHASE2 |
| NCT03350542 | COMPLETED | Coronary Artery Disease |
Boston Scientific Corporation |
2018-04-12 | PHASE3 |
| NCT02837757 | TERMINATED | Metastatic Renal Cancer |
Centre Hospitalier Universitaire de Besancon |
2015-11 | |
| NCT02836847 | UNKNOWN | Cholangiocarcinoma of the Extrahepatic Bile Duct; Gallbladder Cancer |
Shanghai Jiao Tong University School of Medicine |
2016-07 | PHASE2 |
| NCT03040934 | UNKNOWN | Drug-Eluting Stents; Percutaneous Coronary Intervention; Tomography, Optical Coherence |
Shanghai MicroPort Medical (Group) Co., Ltd. |
2017-11-10 | |
| NCT03484234 | TERMINATED | Coronary Artery Disease; Coronary Stenosis |
Seung-Jung Park |
2018-07-27 | |
| NCT02974686 | TERMINATED | Kidney Transplant Rejection; Gastrointestinal Disorder, Functional |
Washington University School of Medicine |
2016-11 | PHASE4 |
| NCT01936519 | COMPLETED | Immunosuppression; Renal Failure |
Milton S. Hershey Medical Center |
2013-12-16 | |
| NCT03256864 | COMPLETED | Liver Transplantation |
Chang Gung Memorial Hospital |
2016-01 | PHASE4 |
| NCT02188719 | TERMINATED | Liver Transplantation |
National Institute of Allergy and Infectious Diseases (NIAID) |
2014-12-17 | PHASE1 |
| NCT01783756 | COMPLETED | Central Nervous System Metastases; HER2-positive Breast Cancer; Male Breast Cancer; Recurrent Breast Cancer; Stage IV Breast Cancer |
Jonsson Comprehensive Cancer Center |
2013-06-26 | PHASE1; PHASE2 |
| NCT02796157 | UNKNOWN | Coronary Artery Disease |
Yonsei University |
2016-06 | |
| NCT03352427 | TERMINATED | Glioma; High Grade Glioma; Pontine Tumors |
University of Michigan Rogel Cancer Center |
2017-12-06 | PHASE2 |
| NCT02579031 | COMPLETED | Coronary Artery Disease; Acute Coronary Syndrome |
Insel Gruppe AG, University Hospital Bern |
2016-04 | |
| NCT01453504 | COMPLETED | Hodgkin Lymphoma |
University of Cologne |
2012-08 | PHASE1; PHASE2 |
| NCT03285802 | COMPLETED | Uterine Cancer |
Greater Baltimore Medical Center |
2017-09-07 | PHASE2; PHASE3 |
| NCT01627067 | TERMINATED | Breast Cancer |
M.D. Anderson Cancer Center |
2012-09 | PHASE2 |
| NCT01270321 | COMPLETED | Thyroid Cancer |
Emory University |
2010-11 | PHASE2 |
| NCT02333565 | COMPLETED | Recurrent Meningiomas; Resistant Meningiomas |
Assistance Publique Hopitaux De Marseille |
2015-01-22 | PHASE2 |
| NCT02077556 | COMPLETED | Drug Interaction Potentiation |
National Taiwan University Hospital |
2014-04 | PHASE4 |
| NCT01061788 | COMPLETED | Advanced Solid Tumors, Non-small Cell Lung Cancer |
Jeffrey Clarke |
2010-04 | PHASE1 |
| NCT02015559 | COMPLETED | Estrogen Receptor-positive Breast Cancer; HER2-negative Breast Cancer; Oral Complications; Progesterone Receptor-positive Breast Cancer; Recurrent Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer |
Jonsson Comprehensive Cancer Center |
2014-10-08 | PHASE2 |
| NCT02344550 | COMPLETED | Metastatic Breast Cancer |
Asan Medical Center |
2014-01 | PHASE2 |
| NCT01469572 | COMPLETED | Neuroendocrine Tumors |
Emory University |
2011-12 | PHASE1 |
| NCT01239342 | TERMINATED | Metastatic Kidney Carcinoma; Recurrent Renal Cell Carcinoma; Stage III Renal Cell Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7 |
National Cancer Institute (NCI) |
2011-01-27 | PHASE2 |
| NCT01678664 | COMPLETED | Neuroendocrine Tumors; Hepatic Metastases; Metastases |
Federation Francophone de Cancerologie Digestive |
2012-12 | PHASE2 |
| NCT01954693 | UNKNOWN | Tuberous Sclerosis |
Cardiff University |
2012-06 | PHASE2 |
| NCT02008019 | SUSPENDED | Chondrosarcoma |
Centre Leon Berard |
2014-08-14 | PHASE2 |
| NCT01976390 | COMPLETED | Renal Failure |
Ohio State University |
2013-10-01 | |
| NCT02049957 | COMPLETED | Breast Cancer |
Calithera Biosciences, Inc |
2014-02-13 | PHASE2 |
| NCT03014297 | TERMINATED | Neuroendocrine Tumors; Everolimus |
Lowell Anthony, MD |
2017-03-06 | PHASE1 |
| NCT03373903 | ACTIVE_NOT_RECRUITING | Respiratory Tract Infections |
Restorbio Inc. |
2017-11-15 | PHASE2 |
| NCT01864070 | WITHDRAWN | Liver Cancer |
M.D. Anderson Cancer Center |
2014-05 | PHASE1 |
| NCT03401216 | UNKNOWN | Ischemic Heart Disease; Coronary Artery Disease; Coronary Atherosclerosis |
Meshalkin Research Institute of Pathology of Circulation |
2017-03-20 | |
| NCT02504892 | TERMINATED | Renal Cancer; Birt-Hogg-Dube Syndrome |
National Cancer Institute (NCI) |
2015-07-21 | PHASE2 |
| NCT01111058 | TERMINATED | Head and Neck Cancer |
University of Chicago |
2010-04 | PHASE2 |
| NCT02376985 | COMPLETED | Breast Cancer |
Comprehensive Support Project for Oncology Research |
2015-03-26 | PHASE3 |
| NCT01942070 | UNKNOWN | Cardiovascular Disease; Myocardial Infarction; Thrombus; Primary Angioplasty |
Deutsches Herzzentrum Muenchen |
2013-09 | |
| NCT02577458 | UNKNOWN | Renal Cell Carcinoma Recurrent |
AnewPharma |
2015-09 | PHASE1 |
| NCT02890589 | COMPLETED | Acute Coronary Syndrome |
University Hospital, Toulouse |
2016-07 | |
| NCT02338570 | TERMINATED | Renal Cell Carcinoma |
Mario Negri Institute for Pharmacological Research |
2015-07 | PHASE4 |
| NCT02429869 | COMPLETED | HIV; Kidney Transplant; Liver Transplant |
University of California, San Francisco |
2016-02-24 | PHASE4 |
| NCT01376310 | TERMINATED | Cancer |
Novartis Pharmaceuticals |
2010-11-02 | PHASE2 |
| NCT01948960 | COMPLETED | Breast Neoplasms |
Radboud University Medical Center |
2013-08 | PHASE4 |
| NCT01636908 | COMPLETED | Cancer; Advanced Solid Tumors |
Amsterdam UMC, location VUmc |
2011-08 | |
| NCT00827359 | COMPLETED | Renal Cell Carcinoma; Renal Cancer |
Beth Israel Deaconess Medical Center |
2009-03 | PHASE2 |
| NCT02014818 | UNKNOWN | Coronary Artery Disease |
Kobe University |
2014-01 | |
| NCT01397175 | TERMINATED | Coronary Artery Disease |
Yonsei University |
2013-01-16 | |
| NCT01190241 | TERMINATED | Advanced Solid Tumors; Inoperable; Metastasis |
Amsterdam UMC, location VUmc |
2010-08 | |
| NCT01858077 | UNKNOWN | Coronary Artery Disease; Myocardial Infarction |
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) |
2013-08 | |
| NCT02134899 | COMPLETED | Autosomal Dominant Polycystic Kidney Disease |
Assistance Publique - Hôpitaux de Paris |
2014-10-14 | PHASE3 |
| NCT01878786 | TERMINATED | Delayed Graft Function |
Matthew Cooper |
2013-06 | PHASE2; PHASE3 |
| NCT01979744 | COMPLETED | Coronary Artery Disease |
Yonsei University |
2013-10 | |
| NCT01713946 | COMPLETED | Tuberous Sclerosis Complex-associated Refractory Seizures |
Novartis Pharmaceuticals |
2013-04-29 | PHASE3 |
| NCT01107509 | COMPLETED | Carcinoma, Renal Cell |
St. Joseph's Healthcare Hamilton |
2010-10-01 | |
| NCT01665768 | COMPLETED | CD20+, B-cell Lymphomas; Mantle Cell Lymphoma; Non-Mantle Cell Low Grade B Cell Lymphomas (SLL/CLL); Transformed Lymphoma/DLBCL/PMBCL; Hodgkin's Disease; Gray Zone Lymphoma |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2012-09 | PHASE2 |
| NCT02864706 | COMPLETED | Heart Transplantation |
Novartis Pharmaceuticals |
2016-01-18 | PHASE4 |
| NCT02112981 | UNKNOWN | Coronary Artery Disease |
Meril Life Sciences Pvt. Ltd. |
2014-11-05 | |
| NCT02894255 | UNKNOWN | Coronary Artery Disease |
Teikyo University |
2016-09 | PHASE4 |
| NCT02352844 | COMPLETED | Solid Malignancy; Solid Tumor |
Washington University School of Medicine |
2015-10-07 | PHASE2 |
| NCT02031536 | TERMINATED | Gastrinoma; Glucagonoma; Insulinoma; Liver Metastases; Pancreatic Polypeptide Tumor; Recurrent Islet Cell Carcinoma; Somatostatinoma |
ECOG-ACRIN Cancer Research Group |
2014-04-10 | PHASE2 |
| NCT00912340 | COMPLETED | Breast Cancer |
Emory University |
2009-05 | PHASE2 |
| NCT01206764 | COMPLETED | Renal Cell Carcinoma |
Novartis Pharmaceuticals |
2009-11-11 | PHASE4 |
| NCT01259063 | COMPLETED | Bladder Cancer |
Memorial Sloan Kettering Cancer Center |
2010-12 | PHASE1; PHASE2 |
| NCT02454478 | COMPLETED | Carcinoma, Renal Cell |
Eisai Co., Ltd. |
2015-07-01 | PHASE1 |
| NCT00767819 | COMPLETED | Progressive Sarcoma |
Novartis Pharmaceuticals |
2008-03-31 | PHASE2 |
| NCT02013089 | UNKNOWN | Gastrointestinal Cancers |
Sun Yat-sen University |
2013-12 | |
| NCT01470209 | COMPLETED | Solid Tumors; Lung Cancer |
Emory University |
2012-01 | PHASE1 |
| NCT02096107 | COMPLETED | Graft Dysfunction; Interstitial Fibrosis |
Medical University of South Carolina |
2014-02 | PHASE4 |
| NCT01215136 | TERMINATED | Transitional Cell Carcinoma; Bladder Carcinoma; Urothelial Carcinoma |
Matthew Galsky |
2010-12 | PHASE2 |
| NCT01752894 | COMPLETED | Ischemic Heart Disease |
Yonsei University |
2013-01-02 | |
| NCT02063958 | COMPLETED | Cancer |
Esanex Inc. |
2014-02 | PHASE1 |
| NCT01797120 | COMPLETED | Metastatic Breast Cancer |
PrECOG, LLC. |
2013-05-31 | PHASE2 |
| NCT01489761 | TERMINATED | Coronary Artery Disease |
Seung-Jung Park |
2012-01 | PHASE4 |
| NCT01967199 | TERMINATED | Coronary Restenosis |
Seung-Jung Park |
2013-04-18 | PHASE4 |
| NCT01950819 | COMPLETED | End Stage Renal Disease (ESRD); Chronic Kidney Disease (CKD); Hemodialysis; Renal Replacement Therapy; Renal Transplantation |
Novartis Pharmaceuticals |
2013-12-03 | PHASE4 |
| NCT01404325 | COMPLETED | Lung Transplantation |
Novartis Pharmaceuticals |
2012-02-01 | PHASE3 |
| NCT01523977 | COMPLETED | Acute Lymphoblastic Leukemia |
Dana-Farber Cancer Institute |
2011-11 | PHASE1 |
| NCT02313051 | UNKNOWN | Metastatic Breast Cancer |
Chinese Academy of Medical Sciences |
2014-12 | PHASE2 |
| NCT01034631 | COMPLETED | Renal Cell Carcinoma |
Hoosier Cancer Research Network |
2010-01 | PHASE1; PHASE2 |
| NCT01545817 | TERMINATED | Carcinoma, Renal Cell |
Novartis Pharmaceuticals |
2012-04-19 | PHASE2 |
| NCT01544491 | COMPLETED | Prevention of Acute Rejection in Paediatric Recipients of a Renal Transplant |
Novartis Pharmaceuticals |
2012-08-17 | PHASE3 |
| NCT02520180 | COMPLETED | Coronary Artery Disease |
Shanghai MicroPort Medical (Group) Co., Ltd. |
2015-12 | |
| NCT01751906 | COMPLETED | Coronary Artery Disease; Coronary Artery Stenosis; Coronary Disease; Coronary Stenosis |
Abbott Medical Devices |
2012-12 | |
| NCT01743560 | COMPLETED | Oestrogen Receptor Positive Advanced Breast Cancer |
Novartis Pharmaceuticals |
2013-01-31 | PHASE4 |
| NCT01595009 | COMPLETED | Neuroendocrine Tumors |
Novartis Pharmaceuticals |
2011-04-27 | PHASE4 |
| NCT01305941 | COMPLETED | HER-2 Positive Breast Cancer |
UNC Lineberger Comprehensive Cancer Center |
2011-09 | PHASE2 |
| NCT01707849 | COMPLETED | Hepatitis C Recurrence After Liver Transplant |
Hospital Vall d'Hebron |
2012-10 | PHASE3 |
| NCT01425281 | COMPLETED | Coronary Artery Disease |
Abbott Medical Devices |
2011-11 | |
| NCT01231399 | COMPLETED | Adenocarcinoma of the Esophagus; Adenocarcinoma of the Gastroesophageal Junction; Diffuse Adenocarcinoma of the Stomach; Intestinal Adenocarcinoma of the Stomach; Mixed Adenocarcinoma of the Stomach; Recurrent Esophageal Cancer; Recurrent Gastric Cancer; Stage IV Esophageal Cancer; Stage IV Gastric Cancer |
City of Hope Medical Center |
2012-02 | PHASE1; PHASE2 |
| NCT01854606 | COMPLETED | CD79 Mutant or ABC-subtype Diffuse Large B-Cell Lymphoma |
Novartis Pharmaceuticals |
2013-12-05 | PHASE1 |
| NCT01598987 | COMPLETED | Renal Function; Liver Transplant |
Novartis Pharmaceuticals |
2012-10 | PHASE3 |
| NCT01252251 | COMPLETED | Uveal Melanoma |
Memorial Sloan Kettering Cancer Center |
2010-11 | PHASE2 |
| NCT01514448 | COMPLETED | Metastatic Renal Cell Carcinoma (mRCC) |
Novartis Pharmaceuticals |
2012-05-21 | PHASE4 |
| NCT02449538 | COMPLETED | Solid Tumor |
Samsung Medical Center |
2015-02 | PHASE2 |
| NCT00997828 | TERMINATED | Coronary Artery Disease |
Seung-Jung Park |
2008-07-28 | |
| NCT02069093 | COMPLETED | Advanced Breast Cancer |
Novartis Pharmaceuticals |
2014-05 | PHASE2 |
| NCT01972022 | UNKNOWN | Coronary Artery Lesions |
A.O. Ospedale Papa Giovanni XXIII |
2013-11 | PHASE4 |
| NCT01182168 | COMPLETED | Bladder Cancer; Renal Pelvis Cancer; Ureter Cancer |
Memorial Sloan Kettering Cancer Center |
2010-08 | PHASE1 |
| NCT01895049 | COMPLETED | Kidney Transplantation; Cytomegalovirus |
Helio Tedesco Silva Junior |
2013-08 | PHASE4 |
| NCT02040584 | COMPLETED | Liver Transplant |
Novartis Pharmaceuticals |
2013-12-20 | PHASE3 |
| NCT01911546 | COMPLETED | Highly-sensitized Kidney Transplant Recipients |
Joseph Kahwaji, MD, MPH |
2013-06 | PHASE2 |
| NCT02569125 | WITHDRAWN | Segmental Overgrowth Syndrome |
Jochen Roessler |
2016-01 | PHASE2 |
| NCT01698918 | COMPLETED | Hormone Receptor Positive Breast Cancer |
Novartis Pharmaceuticals |
2013-03-07 | PHASE2 |
| NCT00918333 | COMPLETED | Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; B-cell Adult Acute Lymphoblastic Leukemia; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Post-transplant Lymphoproliferative Disorder; Primary Central Nervous System Non-Hodgkin Lymphoma; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Multiple Myeloma; Splenic Marginal Zone Lymphoma; T-cell Adult Acute Lymphoblastic Leukemia; Waldenström Macroglobulinemia |
Mayo Clinic |
2009-06 | PHASE1; PHASE2 |
| NCT01410448 | COMPLETED | Kidney Transplantation |
Novartis Pharmaceuticals |
2011-11 | PHASE3 |
| NCT02036554 | UNKNOWN | Kidney; Complications, Allograft |
Seoul St. Mary's Hospital |
2013-03 | PHASE4 |
| NCT01489202 | UNKNOWN | Coronary Artery Disease |
University of Roma La Sapienza |
2014-09 | PHASE4 |
| NCT00814788 | COMPLETED | Prostate Cancer |
University of California, Davis |
2008-12 | PHASE2 |
| NCT02616848 | UNKNOWN | Triple Negative Breast Cancer |
Istituti Ospitalieri di Cremona |
2015-11 | PHASE1 |
| NCT01730209 | UNKNOWN | Tuberous Sclerosis Complex; TSC Related Cognitive Disability; TSC Related Autism; TSC Related Learning Problems |
Erasmus Medical Center |
2012-11 | PHASE2; PHASE3 |
| NCT01566279 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
UMC Utrecht |
2012-08 | |
| NCT00856856 | COMPLETED | Coronary Disease; Coronary Artery Disease; Coronary Restenosis |
Abbott Medical Devices |
2009-03 | |
| NCT01303640 | COMPLETED | Coronary Artery Disease |
Takeshi Morimoto |
2011-05 | PHASE4 |
| NCT01582009 | TERMINATED | Clear Cell Renal Cell Carcinoma; Recurrent Renal Cell Cancer; Stage III Renal Cell Cancer; Stage IV Renal Cell Cancer |
Roswell Park Cancer Institute |
2010-03 | PHASE1; PHASE2 |
| NCT02499692 | COMPLETED | Cardiovascular Diseases |
Boston Scientific Corporation |
2015-05 | |
| NCT00997763 | COMPLETED | Coronary Artery Disease |
Seung-Jung Park |
2008-07 | PHASE4 |
| NCT01268371 | UNKNOWN | Coronary Artery Disease |
Ajou University School of Medicine |
2010-12 | PHASE4 |
| NCT00514514 | COMPLETED | Kidney Transplantation |
Novartis Pharmaceuticals |
2007-07 | PHASE3 |
| NCT01007942 | COMPLETED | HER2/Neu Over-expressing Locally Advanced Breast Cancer; Metastatic Breast Cancer |
Novartis Pharmaceuticals |
2009-10 | PHASE3 |
| NCT02314312 | UNKNOWN | Transplantation of Kidney; Expanded Criteria Donor; ECD |
Mahidol University |
2012-01 | PHASE3 |
| NCT01239472 | COMPLETED | Renal Transplant Rejection; Immunosuppression |
Andre Barreto Pereira |
2011-01 | PHASE4 |
| NCT01865747 | COMPLETED | Renal Cell Carcinoma |
Exelixis |
2013-06 | PHASE3 |
| NCT01668784 | COMPLETED | Advanced or Metastatic (Medically or Surgically Unresectable) Clear-cell Renal Cell Carcinoma |
Bristol-Myers Squibb |
2012-10-09 | PHASE3 |
| NCT00828087 | COMPLETED | Myocardial Infarction |
Spanish Society of Cardiology |
2008-12 | |
| NCT01960829 | UNKNOWN | Melanoma; TOR Serine-Threonine Kinases; Neoplasm Metastasis |
Peking University Cancer Hospital & Institute |
2013-09 | PHASE2 |
| NCT03125772 | COMPLETED | Type 2 Diabetes; Coronary Heart Disease |
Fortis Escorts Heart Institute |
2011-06 | |
| NCT00903175 | COMPLETED | Renal Cell Carcinoma |
Novartis Pharmaceuticals |
2009-10 | PHASE2 |
| NCT01365468 | TERMINATED | Plexiform Neurofibroma Associated With Neurofibromatosis Type 1 |
Novartis Pharmaceuticals |
2012-04 | PHASE2 |
| NCT01469884 | COMPLETED | Renal Allograft; Hepatitis C |
Irmandade Santa Casa de Misericórdia de Porto Alegre |
2011-11 | PHASE4 |
| NCT01598038 | TERMINATED | Renal Cell Carcinoma |
Centre Francois Baclesse |
2012-04 | |
| NCT01488487 | COMPLETED | Advanced Adult Hepatocellular Carcinoma |
UNC Lineberger Comprehensive Cancer Center |
2011-12 | PHASE2 |
| NCT01844284 | COMPLETED | Coronary Artery Disease; Myocardial Ischemia |
Abbott Medical Devices |
2013-04 | |
| NCT01133678 | TERMINATED | Head and Neck Cancer |
University of Chicago |
2010-05-04 | PHASE2 |
| NCT01663805 | UNKNOWN | Delayed Function of Renal Transplant |
MARIO ABBUD FILHO |
2012-01 | PHASE4 |
| NCT01680861 | COMPLETED | Transplant; Failure, Kidney |
Gaetano Ciancio |
2012-11 | PHASE3 |
| NCT01137019 | UNKNOWN | Coronary Heart Disease |
Dr Peter Barlis |
2010-10 | PHASE3 |
| NCT01114529 | COMPLETED | Kidney Transplantation |
Novartis Pharmaceuticals |
2010-08-09 | PHASE3 |
| NCT01801137 | COMPLETED | Urothelial Cancer |
Hopital Foch |
2011-06 | PHASE2 |
| NCT01700400 | COMPLETED | Non Small Cell Lung Cancer |
Cancer Research and Biostatistics Clinical Trials Consortium |
2012-09 | PHASE1 |
| NCT01158651 | COMPLETED | Glioma |
University of Alabama at Birmingham |
2010-07-10 | PHASE2 |
| NCT01229943 | COMPLETED | Advanced Pancreatic Neuroendocrine Tumor; Locally Advanced Pancreatic Neuroendocrine Tumor; Pancreatic Gastrinoma; Pancreatic Neuroendocrine Tumor G1; Pancreatic Neuroendocrine Tumor G2; Pancreatic Vipoma |
National Cancer Institute (NCI) |
2010-10-15 | PHASE2 |
| NCT01628913 | TERMINATED | Pancreatic Neuroendocrine Tumors (pNET) |
Novartis Pharmaceuticals |
2012-10 | PHASE2 |
| NCT01787799 | COMPLETED | Atherosclerotic Lesion(s) |
Boston Scientific Corporation |
2013-03 | PHASE3 |
| NCT01653041 | COMPLETED | Kidney Transplantation |
Hospital do Rim e Hipertensão |
2012-08 | PHASE4 |
| NCT01589978 | COMPLETED | Coronary Artery Disease |
Boston Scientific Corporation |
2012-05 | PHASE4 |
| NCT01966159 | COMPLETED | Coronary Artery Disease |
Boston Scientific Corporation |
2013-10 | |
| NCT01608412 | UNKNOWN | Kidney Transplant Recipients |
Hospital de Clinicas de Porto Alegre |
2012-02 | PHASE4 |
| NCT01023542 | UNKNOWN | Renal Impairment; Liver Transplantation; Everolimus |
University of Regensburg |
2011-06 | PHASE2; PHASE3 |
| NCT02084446 | COMPLETED | Transplantation Infection; Cytomegalovirus Infections |
Ronaldo de Matos Esmeraldo, MD |
2012-12 | PHASE4 |
| NCT00949949 | COMPLETED | Cholangiocarcinoma of the Gallbladder; Localized Gallbladder Cancer; Unresectable Gallbladder Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
Mayo Clinic |
2009-09 | PHASE1 |
| NCT01427946 | COMPLETED | Non-small Cell Lung Cancer |
Infinity Pharmaceuticals, Inc. |
2011-07 | PHASE1; PHASE2 |
| NCT01443104 | COMPLETED | Coronary Artery Disease; Angina Pectoris; Myocardial Infarction |
Insel Gruppe AG, University Hospital Bern |
2012-02 | |
| NCT01216826 | UNKNOWN | Refractory or Relapsed Osteosarcoma |
Sidnei Epelman |
2011-03 | PHASE2 |
| NCT02062892 | WITHDRAWN | Kidney Transplantation |
University of Colorado, Denver |
2013-12 | PHASE4 |
| NCT01636466 | TERMINATED | Kidney Failure, Chronic |
Ashtar Chami |
2013-06 | PHASE3 |
| NCT01166685 | COMPLETED | Coronary Artery Disease; Coronary Thrombosis |
University Hospital, Basel, Switzerland |
2010-04 | PHASE4 |
| NCT00985192 | COMPLETED | Esophageal Cancer; Gastric Cancer |
Translational Oncology Research International |
2009-09 | PHASE2 |
| NCT01793636 | TERMINATED | Metastatic Clear Cell Renal Carcinoma |
Queen Mary University of London |
2013-02 | PHASE2 |
| NCT00716573 | COMPLETED | Cardiac Transplantation; Chronic Renal Insufficiency |
Hospices Civils de Lyon |
2008-09-16 | PHASE4 |
| NCT00770120 | COMPLETED | Malignant Mesothelioma |
SWOG Cancer Research Network |
2008-12 | PHASE2 |
| NCT01217177 | COMPLETED | Locally Advanced Cervical Cancer |
Novartis Pharmaceuticals |
2011-12 | PHASE1 |
| NCT00426556 | COMPLETED | Metastatic Breast Cancer |
Novartis Pharmaceuticals |
2007-07 | PHASE1 |
| NCT01263353 | COMPLETED | Gastroenteropancreatic Neuroendocrine Tumor of the Pulmonary ot Gastroenteropancreatic System |
Novartis Pharmaceuticals |
2010-11 | PHASE1 |
| NCT01169701 | COMPLETED | Renal Transplant |
Novartis Pharmaceuticals |
2010-08 | PHASE4 |
| NCT01242631 | COMPLETED | Testicular Cancer; Germ Cell Cancer |
Hannover Medical School |
2010-11 | PHASE2 |
| NCT01508663 | UNKNOWN | Coronary Artery Disease |
Yonsei University |
2010-08 | PHASE4 |
| NCT00934895 | TERMINATED | Breast Cancer |
Rutgers, The State University of New Jersey |
2009-07-15 | PHASE1; PHASE2 |
| NCT01423708 | UNKNOWN | Liver Failure; Liver Diseases; Liver Cirrhosis; Liver Neoplasms |
Azienda Ospedaliera di Padova |
2010-02 | PHASE2 |
| NCT00698607 | COMPLETED | Coronary Artery Disease |
Seoul National University Hospital |
2008-06 | PHASE4 |
| NCT01486095 | UNKNOWN | True Coronary Bifurcation Lesions |
Universitaire Ziekenhuizen KU Leuven |
2011-11-29 | |
| NCT01525719 | UNKNOWN | Cholangiocarcinoma |
Ratchavithi Hospital |
2012-01 | PHASE2 |
| NCT01017029 | COMPLETED | Cardiac Transplantation |
Novartis Pharmaceuticals |
2009-09 | PHASE4 |
| NCT01561404 | TERMINATED | Disorder Related to Renal Transplantation; Exercise, Aerobic; Muscle Strength |
Josep M Cruzado |
2011-09 | PHASE4 |
| NCT00828503 | UNKNOWN | Cytomegalovirus Disease |
Marcus Saemann |
2008-12 | PHASE2 |
| NCT01125293 | TERMINATED | Waldenstrom's Macroglobulinemia |
Dana-Farber Cancer Institute |
2010-04 | PHASE1; PHASE2 |
| NCT01626222 | COMPLETED | Metastatic Breast Cancer |
Novartis Pharmaceuticals |
2012-06 | PHASE3 |
| NCT00831480 | TERMINATED | Kidney Cancer |
Linda C. Higgins |
2011-04 | PHASE2 |
| NCT01216839 | UNKNOWN | Refractory or Relapsed RMS and Soft Tissue Sarcomas |
Sidnei Epelman |
2011-03 | PHASE2 |
| NCT00930930 | COMPLETED | Breast Cancer |
Vanderbilt-Ingram Cancer Center |
2009-06 | PHASE2 |
| NCT01594268 | COMPLETED | Kidney Transplant |
Novartis Pharmaceuticals |
2012-03 | PHASE4 |
| NCT01035229 | COMPLETED | Carcinoma |
Novartis Pharmaceuticals |
2010-04 | PHASE3 |
| NCT00414440 | COMPLETED | Autosomal Dominant Polycystic Kidney Disease |
Novartis Pharmaceuticals |
2006-12 | PHASE4 |
| NCT01051570 | COMPLETED | Prostate Cancer |
Barbara Ann Karmanos Cancer Institute |
2010-02 | PHASE2 |
| NCT01099527 | COMPLETED | Metastatic Gastric Cancer |
Samsung Medical Center |
2009-10 | PHASE1; PHASE2 |
| NCT02018991 | COMPLETED | Late Acquired Stent Malaposition |
Medical University of Vienna |
2010-10 | PHASE4 |
| NCT01167530 | COMPLETED | Non-small Cell Lung Cancer; Locally Advanced Disease |
Gustave Roussy, Cancer Campus, Grand Paris |
2008-02-26 | PHASE1 |
| NCT00858663 | COMPLETED | Head and Neck Cancer |
Memorial Sloan Kettering Cancer Center |
2009-03 | PHASE1 |
| NCT00636922 | UNKNOWN | Acute Myeloid Leukemia |
Bayside Health |
2010-02 | PHASE1 |
| NCT01567475 | COMPLETED | Non-Hodgkin's Lymphomas |
The Lymphoma Academic Research Organisation |
2011-12 | PHASE1 |
| NCT00965094 | COMPLETED | Chronic Renal Failure |
Novartis Pharmaceuticals |
2009-12 | PHASE4 |
| NCT01012869 | COMPLETED | Coronary Occlusions |
North Texas Veterans Healthcare System |
2009-11 | PHASE4 |
| NCT01609673 | TERMINATED | End Stage Renal Failure With Renal Transplant |
Helady Pinheiro, MD, PhD |
2013-03 | |
| NCT01887704 | COMPLETED | Coronary Artery Disease |
Capital Medical University |
2010-01 | |
| NCT00634920 | COMPLETED | Renal Function |
Novartis Pharmaceuticals |
2008-03 | PHASE4 |
| NCT01932177 | UNKNOWN | Metastatic or Locally Advanced Solid Tumors |
Hospices Civils de Lyon |
2013-04 | PHASE1 |
| NCT01334073 | COMPLETED | Malignant Advanced Solid Tumors; Carcinoma, Renal Cell |
University Hospital, Bordeaux |
2011-03 | PHASE1 |
| NCT00610948 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
UNC Lineberger Comprehensive Cancer Center |
2008-03 | PHASE1 |
| NCT01605721 | UNKNOWN | Coronary Artery Disease |
Seoul National University Hospital |
2011-05 | PHASE4 |
| NCT02056587 | COMPLETED | Metastatic Renal Cell Carcinoma |
Kidney Cancer Research Bureau |
2011-11 | PHASE4 |
| NCT00956293 | TERMINATED | Renal Transplantation |
Novartis Pharmaceuticals |
2009-07 | PHASE4 |
| NCT01703000 | COMPLETED | Atherosclerosis; Coronary Artery Disease |
Boston Scientific Corporation |
2012-11 | |
| NCT00332839 | TERMINATED | Renal Transplantation |
Novartis Pharmaceuticals |
2005-11 | PHASE4 |
| NCT00570921 | COMPLETED | Breast Cancer |
Mara Chambers |
2008-04 | PHASE2 |
| NCT01272141 | TERMINATED | Breast Neoplasms; Breast Cancer; Cancer of the Breast |
Emory University |
2010-12 | PHASE2 |
| NCT00962507 | COMPLETED | Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm |
City of Hope Medical Center |
2009-07 | PHASE1 |
| NCT01164267 | COMPLETED | Marginal Zone B-cell Lymphoma |
International Extranodal Lymphoma Study Group (IELSG) |
2010-03 | PHASE2 |
| NCT00788060 | COMPLETED | Renal Cell Carcinoma |
Daniel George, MD |
2008-10 | PHASE1 |
| NCT01331707 | COMPLETED | Acute Coronary Syndrome; Angina Pectoris; Angina, Unstable; Myocardial Infarction; Coronary Artery Disease; Coronary Stenosis; Coronary Restenosis |
Foundation of Cardiovascular Research and Education Enschede |
2010-11 | PHASE4 |
| NCT00943956 | COMPLETED | Prostate Cancer |
Institut du Cancer de Montpellier - Val d'Aurelle |
2009-01 | PHASE1 |
| NCT01266148 | COMPLETED | Renal Function and Chronic Allograft Vasculopathy |
Novartis Pharmaceuticals |
2009-11 | PHASE4 |
| NCT00976755 | COMPLETED | Prostate Cancer |
Swiss Cancer Institute |
2009-09-14 | PHASE2 |
| NCT01231659 | COMPLETED | Postmenopausal Women; Locally Advanced Metastatic Breast Cancer; Metastatic Breast Cancer |
Novartis Pharmaceuticals |
2011-08-09 | PHASE2 |
| NCT00510354 | COMPLETED | Progressive Gastrointestinal Stromal Tumor |
Novartis Pharmaceuticals |
2006-10 | PHASE4 |
| NCT01341340 | TERMINATED | Atherosclerosis; Peripheral Artery Disease; Peripheral Vascular Disease; PAD; Claudication; Critical Limb Ischemia; Lower Limb Disease; Peripheral Arterial Occlusive Disease; PAOD; PVD |
Abbott Medical Devices |
2011-11 | |
| NCT01178268 | COMPLETED | Coronary Occlusion; Thrombosis (Stent Thrombosis); Vascular Disease; Myocardial Ischemia; Coronary Artery Stenosis; Coronary Disease; Coronary Artery Disease; Coronary Restenosis |
Abbott Medical Devices |
2010-08 | PHASE4 |
| NCT01714765 | COMPLETED | Metastatic Clear Cell Renal Cancer |
Queen Mary University of London |
2011-04 | PHASE1 |
| NCT00276575 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Herbert Hurwitz, MD |
2005-03 | PHASE1 |
| NCT01524601 | COMPLETED | Disorder Related to Renal Transplantation; Hypercholesterolemia |
University of Oslo School of Pharmacy |
2012-02 | PHASE4 |
| NCT01313559 | TERMINATED | Castrate Resistant Prostate Cancer; Chemotherapy Naive Prostate Cancer; Prostate Cancer |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2011-06 | PHASE2 |
| NCT00632268 | COMPLETED | Metastatic Gastric Cancer |
National Taiwan University Hospital |
2008-02 | PHASE2 |
| NCT01096199 | TERMINATED | Cancer |
National University Hospital, Singapore |
PHASE1 | |
| NCT01405287 | COMPLETED | Coronary Artery Disease; Atherosclerosis; Acute Coronary Syndrome (ACS); Myocardial Infarction (MI) |
OrbusNeich |
2011-10 | PHASE2 |
| NCT01149434 | TERMINATED | Cancer; Neuroendocrine; Ovarian Cancer; Colon Cancer |
University of Utah |
2010-09 | PHASE1; PHASE2 |
| NCT01276834 | TERMINATED | Renal Transplantation |
Dianet Dialysis Centers |
2010-09 | PHASE4 |
| NCT00820911 | COMPLETED | Kidney Transplantation |
Novartis Pharmaceuticals |
2008-09 | PHASE2 |
| NCT01436123 | TERMINATED | Coronary Artery Disease; Atherosclerosis |
Ural State Medical University |
2010-12 | PHASE1 |
| NCT01023815 | COMPLETED | de Novo Kidney Transplant Recipients; Renal Transplantation |
Novartis |
2009-04 | PHASE3 |
| NCT01079481 | COMPLETED | Small Cell Lung Cancer |
Samsung Medical Center |
2009-12 | PHASE1 |
| NCT01233453 | UNKNOWN | Coronary Artery Disease |
Maasstad Hospital |
2009-01 | PHASE4 |
| NCT01118065 | UNKNOWN | Head and Neck Cancer |
Leiden University Medical Center |
2010-05 | PHASE2 |
| NCT01196819 | COMPLETED | Coronary Artery Disease |
Shanghai MicroPort Medical (Group) Co., Ltd. |
2010-09 | |
| NCT00622869 | COMPLETED | Liver Transplantation |
Novartis Pharmaceuticals |
2008-01 | PHASE3 |
| NCT01312064 | TERMINATED | Renal Insufficiency |
National Taiwan University Hospital |
2011-04 | PHASE4 |
| NCT01163929 | WITHDRAWN | Breast Cancer |
University of Kansas |
2010-07 | PHASE2 |
| NCT01329237 | UNKNOWN | Coronary Artery Disease |
University of Freiburg |
2011-03 | PHASE4 |
| NCT01014351 | COMPLETED | Metastatic Melanoma |
SCRI Development Innovations, LLC |
2010-02 | PHASE2 |
| NCT00719264 | COMPLETED | Carcinoma; Adenocarcinoma; Renal Cell; Nephroid Carcinoma; Hypernephroid |
Novartis Pharmaceuticals |
2008-11-12 | PHASE2 |
| NCT01267734 | UNKNOWN | Coronary Heart Disease |
Seoul National University Hospital |
2010-06 | PHASE4 |
| NCT01031446 | COMPLETED | Breast Cancer |
Vanderbilt-Ingram Cancer Center |
2009-10 | PHASE1; PHASE2 |
| NCT01230723 | UNKNOWN | Coronary Heart Disease |
Deutsches Herzzentrum Muenchen |
2010-10 | PHASE4 |
| NCT00955773 | COMPLETED | Cancer |
GlaxoSmithKline |
2009-08-17 | PHASE1 |
| NCT00474929 | COMPLETED | Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm |
Mayo Clinic |
2007-08-29 | PHASE1; PHASE2 |
| NCT00402532 | COMPLETED | Lung Transplantation |
Hannover Medical School |
2005-03 | PHASE3 |
| NCT00869999 | COMPLETED | Diffuse Large B-cell Lymphoma |
Massachusetts General Hospital |
2009-05 | PHASE2 |
| NCT01202058 | TERMINATED | Atherosclerotic Coronary Artery Disease |
Cordis US Corp. |
2010-08 | PHASE3 |
| NCT00423865 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Memorial Sloan Kettering Cancer Center |
2006-11 | PHASE1 |
| NCT01365572 | UNKNOWN | In-stent Arterial Restenosis |
Korea University Anam Hospital |
2010-01 | PHASE4 |
| NCT00729482 | COMPLETED | Stomach Neoplasm |
Asan Medical Center |
2008-07 | PHASE2 |
| NCT01147237 | UNKNOWN | Long Coronary Artery Disease |
Society for Advancement of Coronary Intervention Research |
2010-02 | PHASE4 |
| NCT00793221 | COMPLETED | Coronary Artery Disease; Coronary Occlusion; Percutaneous Coronary Intervention |
Raul Moreno |
2008-11 | PHASE3 |
| NCT00300274 | COMPLETED | Graft Rejection |
Novartis Pharmaceuticals |
2006-01 | PHASE3 |
| NCT00954512 | TERMINATED | Neoplasms |
Merck Sharp & Dohme LLC |
2009-09-25 | PHASE1; PHASE2 |
| NCT00790400 | COMPLETED | Tuberous Sclerosis Complex (TSC); Lymphangioleiomyomatosis (LAM) |
Novartis Pharmaceuticals |
2009-04 | PHASE3 |
| NCT01298713 | COMPLETED | Breast Neoplasms; mTor Protein |
ARCAGY/ GINECO GROUP |
2008-03 | PHASE2 |
| NCT00870337 | COMPLETED | Endometrial Cancer |
ARCAGY/ GINECO GROUP |
2008-03 | PHASE2 |
| NCT01332279 | WITHDRAWN | Recurrent Metastatic Squamous Neck Cancer With Occult Primary; Recurrent Salivary Gland Cancer; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Recurrent Verrucous Carcinoma of the Larynx; Recurrent Verrucous Carcinoma of the Oral Cavity; Salivary Gland Squamous Cell Carcinoma; Tongue Cancer |
Fox Chase Cancer Center |
2011-04 | PHASE1 |
| NCT01051791 | TERMINATED | Squamous Cell Carcinoma of the Head and Neck |
Julie E. Bauman, MD, MPH |
2010-01 | PHASE2 |
| NCT00882219 | COMPLETED | Coronary Restenosis |
Abbott Medical Devices |
2009-03 | PHASE3 |
| NCT01500434 | COMPLETED | Coronary Artery Disease |
Boston Scientific Corporation |
2009-02 | PHASE3 |
| NCT00811590 | TERMINATED | Peutz-Jeghers Syndrome |
University of Utah |
2008-11 | PHASE2 |
| NCT01182428 | COMPLETED | Coronary Artery Stenosis; Coronary Arteriosclerosis; Coronary Artery Disease; Coronary Artery Restenosis; Total Coronary Occlusion; Stent Thrombosis; Vascular Disease; Myocardial Ischemia |
Abbott Medical Devices |
2008-09 | PHASE4 |
| NCT00888758 | UNKNOWN | Coronary Heart Disease; Percutaneous Coronary Intervention |
Masaryk University |
2009-05 | PHASE4 |
| NCT00560963 | COMPLETED | Advanced or Metastatic Pancreatic Adenocarcinoma |
Novartis Pharmaceuticals |
2007-10 | PHASE1; PHASE2 |
| NCT00775073 | COMPLETED | Hepatocellular Carcinoma |
Gerhard Treiber |
2008-10 | PHASE2 |
| NCT00611286 | COMPLETED | Coronary Artery Disease |
Marco Valgimigli |
2006-12 | PHASE4 |
| NCT01498692 | COMPLETED | Coronary Artery Disease |
Boston Scientific Corporation |
2009-02 | |
| NCT00434174 | COMPLETED | Non Small Cell Lung Cancer |
Novartis Pharmaceuticals |
2006-12 | PHASE1 |
| NCT00895791 | WITHDRAWN | Coronary Artery Stenosis |
Universitaire Ziekenhuizen KU Leuven |
2009-06 | |
| NCT00968591 | COMPLETED | Hepatic Insufficiency |
Novartis Pharmaceuticals |
2009-11 | PHASE1 |
| NCT00783796 | TERMINATED | Coronary Artery Disease; Atherosclerosis; Myocardial Ischemia |
Abbott Medical Devices |
2008-10 | |
| NCT01066650 | COMPLETED | Coronary Artery Disease; Angina Pectoris; Unstable Angina Pectoris; Coronary Stenosis; Coronary Restenosis |
Foundation of Cardiovascular Research and Education Enschede |
2008-06 | PHASE4 |
| NCT00807755 | TERMINATED | Lung Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
University of California, Davis |
2009-03 | PHASE1 |
| NCT00303732 | COMPLETED | Kidney Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
Daniel George, MD |
2004-12 | PHASE1 |
| NCT00857259 | TERMINATED | Choroidal Neo-Vascular Age-onset Macular Degeneration; Age-related Macular Degeneration |
Novartis Pharmaceuticals |
2009-02 | PHASE2 |
| NCT00597506 | COMPLETED | Colorectal Adenocarcinoma |
Herbert Hurwitz |
2007-10 | PHASE2 |
| NCT00390195 | UNKNOWN | Hepatocellular Carcinoma |
National Health Research Institutes, Taiwan |
2006-10 | PHASE1; PHASE2 |
| NCT00695344 | UNKNOWN | Cardiac Transplant |
Fundacion Investigacion y Desarrollo |
2006-01 | PHASE4 |
| NCT00426530 | COMPLETED | Breast Neoplasms; Neoplasm Metastasis |
Novartis Pharmaceuticals |
2007-02 | PHASE1 |
| NCT01183247 | COMPLETED | Comparative Study; Immunosuppressive Agents |
University Hospital, Basel, Switzerland |
2008-07 | PHASE4 |
| NCT00617084 | COMPLETED | Coronary Artery Disease |
Medtronic Vascular |
2008-04 | PHASE4 |
| NCT00768846 | UNKNOWN | Coronary Artery Disease |
Deutsches Herzzentrum Muenchen |
2008-09 | PHASE4 |
| NCT01079702 | UNKNOWN | Advanced Malignancies |
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) |
2008-04 | PHASE1; PHASE2 |
| NCT00544999 | UNKNOWN | Leukemia |
Institut de Recherche Clinique sur les Cancers et le Sang |
2007-09 | PHASE1 |
| NCT00458237 | COMPLETED | Breast Cancer |
Beth Israel Deaconess Medical Center |
2007-04 | PHASE1; PHASE2 |
| NCT00640978 | TERMINATED | Pancreatic Cancer |
M.D. Anderson Cancer Center |
2008-03 | PHASE2 |
| NCT00531011 | COMPLETED | Coronary Disease; Coronary Artery Disease; Coronary Artery Stenosis; Coronary Artery Restenosis |
Abbott Medical Devices |
2007-09 | PHASE4 |
| NCT01510327 | COMPLETED | Coronary Artery Disease |
Boston Scientific Corporation |
2009-10 | PHASE3 |
| NCT00516412 | COMPLETED | Lymphoma |
Swiss Cancer Institute |
2007-08 | PHASE2 |
| NCT00582738 | TERMINATED | Recurrent Hepatitis C |
Novartis Pharmaceuticals |
2007-12 | PHASE2 |
| NCT00331409 | COMPLETED | Kidney Cancer |
OHSU Knight Cancer Institute |
2006-01 | PHASE2 |
| NCT00521001 | COMPLETED | Melanoma (Skin) |
Alliance for Clinical Trials in Oncology |
2008-01 | PHASE2 |
| NCT00170846 | COMPLETED | Renal Transplantation |
Novartis Pharmaceuticals |
2005-02 | PHASE4 |
| NCT00655655 | COMPLETED | Gastrinoma; Glucagonoma; Insulinoma; Metastatic Gastrointestinal Carcinoid Tumor; Metastatic Pheochromocytoma; Pancreatic Polypeptide Tumor; Recurrent Gastrointestinal Carcinoid Tumor; Recurrent Islet Cell Carcinoma; Recurrent Melanoma; Recurrent Neuroendocrine Carcinoma of the Skin; Recurrent Non-small Cell Lung Cancer; Recurrent Pheochromocytoma; Recurrent Renal Cell Cancer; Somatostatinoma; Stage III Neuroendocrine Carcinoma of the Skin; Stage IV Melanoma; Stage IV Non-small Cell Lung Cancer; Stage IV Renal Cell Cancer; Thyroid Gland Medullary Carcinoma; Unspecified Adult Solid Tumor, Protocol Specific |
Mayo Clinic |
2004-12 | PHASE1 |
| NCT00515086 | TERMINATED | Glioblastoma Multiforme |
Novartis Pharmaceuticals |
2007-08 | PHASE2 |
| NCT00251004 | COMPLETED | Kidney Transplantation; Graft Rejection |
Novartis |
2005-10 | PHASE3 |
| NCT00505102 | UNKNOWN | Kidney Diseases; Heart Transplantation |
A.O. Ospedale Papa Giovanni XXIII |
2007-01 | PHASE4 |
| NCT00855114 | WITHDRAWN | Breast Cancer |
Masonic Cancer Center, University of Minnesota |
2008-07 | PHASE2 |
| NCT00598676 | COMPLETED | Coronary Heart Disease |
Deutsches Herzzentrum Muenchen |
2007-09 | PHASE4 |
| NCT00419159 | COMPLETED | Colorectal Cancer |
Novartis Pharmaceuticals |
2006-12 | PHASE2 |
| NCT00596557 | COMPLETED | Chronic Rejection of Cardiac Transplant |
Rabin Medical Center |
2008-02 | PHASE4 |
| NCT00519324 | COMPLETED | Advanced Gastric Cancer |
Novartis Pharmaceuticals |
2007-08 | PHASE2 |
| NCT00420537 | TERMINATED | Kidney Dysfunction; Heart Transplantation |
University of Bologna |
2006-09 | PHASE4 |
| NCT00574366 | COMPLETED | Breast Cancer |
Vanderbilt-Ingram Cancer Center |
2005-12 | PHASE1 |
| NCT00374140 | COMPLETED | Small Cell Lung Cancer |
Ahmad Tarhini |
2006-10 | PHASE2 |
| NCT00323739 | COMPLETED | Kidney Cancer |
SCRI Development Innovations, LLC |
2006-05 | PHASE2 |
| NCT00697372 | COMPLETED | Coronary Artery Disease; Coronary Stenosis |
Catholic University of the Sacred Heart |
2007-09 | PHASE4 |
| NCT01269684 | WITHDRAWN | Kidney Transplantation |
Novartis Pharmaceuticals |
2008-08 | PHASE4 |
| NCT00255788 | COMPLETED | Breast Cancer |
NCIC Clinical Trials Group |
2005-05-10 | PHASE2 |
| NCT00154284 | COMPLETED | Organ Transplantation, Renal Transplantation |
Novartis |
2005-07 | PHASE3 |
| NCT00117702 | TERMINATED | Graft vs Host Disease |
Technische Universität Dresden |
2005-10 | PHASE2; PHASE3 |
| NCT00363051 | COMPLETED | Islet Cell Carcinoma; Neuroendocrine Carcinoma; Neuroendocrine Tumor; Pancreatic Neoplasms |
Novartis Pharmaceuticals |
2006-06 | PHASE2 |
| NCT00390364 | TERMINATED | Colorectal Cancer |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2006-10 | PHASE2 |
| NCT00352443 | COMPLETED | Lymphoma; Unspecified Adult Solid Tumor, Protocol Specific |
SWOG Cancer Research Network |
2006-09 | PHASE1 |
| NCT00170885 | COMPLETED | Kidney Transplantation |
Novartis |
2005-05 | PHASE4 |
| NCT00180310 | COMPLETED | Coronary Disease; Coronary Artery Disease; Coronary Restenosis |
Abbott Medical Devices |
2005-07 | PHASE3 |
| NCT00107016 | COMPLETED | Breast Neoplasm |
Novartis Pharmaceuticals |
2005-03 | PHASE2 |
| NCT00098007 | COMPLETED | Heart Transplantation |
Novartis Pharmaceuticals |
2004-08-09 | PHASE3 |
| NCT00170859 | COMPLETED | Heart Transplantation |
Novartis Pharmaceuticals |
2004-08 | PHASE4 |
| NCT00618345 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Mayo Clinic |
2005-03 | PHASE2 |
| NCT00093639 | COMPLETED | Leukemia |
Novartis Pharmaceuticals |
2004-08 | PHASE1; PHASE2 |
| NCT00286624 | COMPLETED | Type 1 Diabetes Mellitus; Hypoglycemia |
University of Minnesota |
2003-03 | PHASE1; PHASE2 |
| NCT00170794 | COMPLETED | Cardiac Transplantation |
Novartis Pharmaceuticals |
2004-09 | PHASE3 |
| NCT00402662 | TERMINATED | Metastatic Melanoma |
Yale University |
2006-02 | PHASE2 |
| NCT00107237 | COMPLETED | Brain and Central Nervous System Tumors |
Novartis Pharmaceuticals |
2003-10 | PHASE1; PHASE2 |
| NCT00170820 | COMPLETED | Renal Transplantation |
Novartis Pharmaceuticals |
2005-02 | PHASE4 |
| NCT00170833 | COMPLETED | Renal Transplantation |
Novartis Pharmaceuticals |
2003-11 | PHASE3 |
| NCT00531440 | COMPLETED | Renal Transplantation |
Novartis Pharmaceuticals |
2001-11 | PHASE3 |
| NCT00097968 | COMPLETED | Graft Rejection |
Novartis Pharmaceuticals |
2004-08 | PHASE3 |
| NCT01093300 | UNKNOWN | In-stent Restenosis Lesion |
Seoul National University Hospital |
PHASE4 | |
| NCT00325325 | UNKNOWN | Kidney Diseases |
Hospital Universitario Ramon y Cajal |
2006-01 | PHASE2 |
| NCT01510509 | UNKNOWN | Diabetes Mellitus; Percutaneous Coronary Intervention |
Hospital Universitario Infanta Cristina |
2009-01 | PHASE4 |
| NCT00443937 | COMPLETED | Renal Transplantation |
Charite University, Berlin, Germany |
2004-01 | PHASE4 |
| NCT00373815 | TERMINATED | Graft Versus Host Disease |
University Hospital Tuebingen |
2006-09 | PHASE1 |
(data from https://clinicaltrials.gov, updated on 2023-02-21)
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
- RAD001 (Everolimus) Mechanism of Action: mTOR Inhibition in Tumor Cell Research
- RAD001 (Everolimus): Selectivity & Specificity
- RAD001 (Everolimus) Working Concentration | Cell Culture | Treatment
- RAD001 (Everolimus) Solubility in DMSO
- RAD001 (Everolimus) Stock Solution
- RAD001 (Everolimus) Storage
- RAD001 (Everolimus) Stability
- RAD001 (Everolimus) Combination Database
- RAD001 (Everolimus) Molecular Weight
- RAD001 (Everolimus) SMILES
- RAD001 (Everolimus) CAS Number
- RAD001 (Everolimus) Chemical Structure (2D and 3D)
- RAD001 (Everolimus) IC50 for Cell-based and Cell-free Assays
- RAD001 (Everolimus) MedChemExpress (HY-10218)? Try a better option.
- RAD001 (Everolimus) Sigma (SML2282)? Try a better option.
- RAD001 (Everolimus) Cayman (11597)? Try a better option.
- RAD001 (Everolimus) Tocris (6188)? Try a better option.
- RAD001 (Everolimus) Abmole (M1709)? Try a better option.
- RAD001 (Everolimus) SDS|MSDS