CAS No. 22368-21-4
Batch:
Purity:99.45
Chemical Structure
Check the
Eupatilin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one | |
|---|---|---|
| CAS Number | 22368-21-4 | |
| Molecular Formula |
C18H16O7 |
|
| Molecular Weight (MW) | 344.32 | |
| SMILES | COC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)OC)O)OC | |
| InChIKey | DRRWBCNQOKKKOL-UHFFFAOYSA-N |
Eupatilin is a natural lipophilic flavonoid isolated from Artemisia species that acts as a peroxisome proliferator-activated receptor alpha (PPARα) agonist. Activation of PPARα by eupatilin suppresses TNF-α-induced expression of cell adhesion molecules and attenuates NF-kB signaling, leading to downstream anti-inflammatory, anti-oxidative, and anti-apoptotic phenotypes in cellular models.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
68 mg/mL
(197.49 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
69 mg/mL
(200.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.