CAS No. 297-76-7

Batch: Purity:99.22
Ethynodiol diacetate Chemical Structure
Chemical Structure
Check the Ethynodiol diacetate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 297-76-7
Molecular Formula

C24H32O4

Molecular Weight (MW) 384.51
SMILES CC(=O)OC1CCC2C3CCC4(C(C3CCC2=C1)CCC4(C#C)OC(=O)C)C

Ordering Information

Biological Activity

Ethynodiol diacetate is a synthetic progestogen that acts as a progesterone receptor agonist. Upon binding to progesterone receptors, it activates intracellular signaling cascades to modulate transcription of target genes involved in reproductive tissue function and neuroendocrine regulation. Through activation of progesterone receptor pathways, it inhibits luteinizing hormone secretion and alters endometrial receptivity, influencing cellular proliferation and differentiation within target tissues.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 77 mg/mL (200.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 77 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.