CAS No. 161796-78-7
Batch:
Purity:99.99
Chemical Structure
Check the
Esomeprazole sodium
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | sodium 5-methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]benzimidazol-1-ide | |
|---|---|---|
| CAS Number | 161796-78-7 | |
| Molecular Formula |
C17H18N3O3S.Na |
|
| Molecular Weight (MW) | 367.4 | |
| SMILES | CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=C(C=C3)OC.[Na+] | |
| InChIKey | RYXPMWYHEBGTRV-JIDHJSLPSA-N |
Esomeprazole sodium is a proton pump inhibitor that targets H+/K+-ATPase in gastric parietal cells. As the S-enantiomer of omeprazole, it is protonated and converted in the acidic compartment of parietal cells into an active sulphenamide intermediate. This active species directly inhibits H+/K+-ATPase activity, thereby blocking the final step of acid production and significantly suppressing gastric acid secretion.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
73 mg/mL
(198.69 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 73 mg/mL |
| Ethanol | 73 mg/mL |
| DMSO |
74 mg/mL
(201.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 74 mg/mL |
| Ethanol | 74 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Esomeprazole sodium Clinical Trials
- Esomeprazole sodium Solubility in DMSO
- Esomeprazole sodium Stock Solution
- Esomeprazole sodium Storage
- Esomeprazole sodium Stability
- Esomeprazole sodium Molecular Weight
- Esomeprazole sodium SMILES
- Esomeprazole sodium Chemical Structure (2D and 3D)
- Esomeprazole sodium SDS|MSDS
Note: Technical data last updated: Sep 1, 2026.