CAS No. 219861-08-2

Batch: Purity:99.68
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Escitalopram Oxalate Chemical Structure
Chemical Structure
Check the Escitalopram Oxalate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile;oxalic acid
CAS Number 219861-08-2
Molecular Formula

C20H21FN2O.C2H2O4
Molecular Weight (MW) 414.43
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F.C(=O)(C(=O)O)O
InChIKey KTGRHKOEFSJQNS-BDQAORGHSA-N

Biological Activity

Escitalopram Oxalate is a selective serotonin reuptake inhibitor (SSRI) that potently targets the serotonin transporter (SERT). By blocking SERT-mediated reuptake of serotonin in the synaptic cleft, it elevates extracellular serotonin levels and enhances serotonergic neurotransmission. In preclinical studies, escitalopram demonstrates high selectivity for SERT over other neurotransmitter transporters and receptors, significantly modulating central serotonergic signaling and downstream behavioral phenotypes in model systems. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 83 mg/mL (200.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 25 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Reference

[1] Owens MJ, et al. Biol Psychiatry. 2001;50(5):345-50.

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Note: Technical data last updated: Sep 1, 2026.