Erastin is a potent system Xc- inhibitor and ferroptosis inducer. It affects Nrf2/HO-1 and AMPK signaling pathways, by depleting intracellular glutathione, decreasing GPX4 activity, and promoting lipid peroxidation and ROS accumulation, to induce ferroptosis and inhibit cancer cell proliferation.
Erastin IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Erastin Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
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- Erastin Mechanism of Action: SLC7A11 Inhibition in Cancer Cell Research
- Erastin Working Concentration | Cell Culture | Treatment
- Erastin Solubility in DMSO
- Erastin Stock Solution
- Erastin Storage
- Erastin Stability
- Erastin Combination Database
- Erastin Molecular Weight
- Erastin SMILES
- Erastin CAS Number
- Erastin Chemical Structure (2D and 3D)
- Erastin Sigma (329600)? Try a better option.
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- Erastin SDS｜MSDS