CAS No. 864070-44-0
Batch:
Purity:99.97
Chemical Structure
Check the
BI-10773 (Empagliflozin)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol | |
|---|---|---|
| CAS Number | 864070-44-0 | |
| Molecular Formula |
C23H27ClO7 |
|
| Molecular Weight (MW) | 450.91 | |
| SMILES | C1COCC1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl | |
| InChIKey | OBWASQILIWPZMG-QZMOQZSNSA-N |
BI-10773 (Empagliflozin) is a selective sodium-glucose cotransporter 2 (SGLT-2) inhibitor (IC50 3.1 nM) that exhibits over 300-fold selectivity over SGLT-1, SGLT-4, SGLT-5, and SGLT-6. By blocking SGLT-2-mediated glucose reabsorption in renal proximal tubules, empagliflozin promotes urinary glucose excretion. This inhibition leads to reduced plasma glucose levels, decreased hyperinsulinemia, and improved glycemic control in preclinical diabetic models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
90 mg/mL
(199.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
90 mg/mL
(199.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
90 mg/mL
(199.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
90 mg/mL
(199.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
90 mg/mL
(199.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- BI-10773 (Empagliflozin) Mechanism of Action: SGLT2 Inhibition in Cardiomyocytes Research
- BI-10773 (Empagliflozin) Clinical Trials
- BI-10773 (Empagliflozin): Selectivity & Specificity
- BI-10773 (Empagliflozin) Working Concentration | Cell Culture | Treatment
- BI-10773 (Empagliflozin) Solubility in DMSO
- BI-10773 (Empagliflozin) Stock Solution
- BI-10773 (Empagliflozin) Storage
- BI-10773 (Empagliflozin) Stability
- BI-10773 (Empagliflozin) Combination Database
- BI-10773 (Empagliflozin) Molecular Weight
- BI-10773 (Empagliflozin) SMILES
- BI-10773 (Empagliflozin) Chemical Structure (2D and 3D)
- BI-10773 (Empagliflozin) IC50 for Cell-based and Cell-free Assays
- BI-10773 (Empagliflozin) Sigma (SML4200)? Try a better option.
- BI-10773 (Empagliflozin) MedChemExpress (HY-15409)? Try a better option.
- BI-10773 (Empagliflozin) Cayman (17375)? Try a better option.
- BI-10773 (Empagliflozin) APExBIO (A4601)? Try a better option.
- BI-10773 (Empagliflozin) Axonmedchem (Axon 3367)? Try a better option.
- BI-10773 (Empagliflozin) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.