CAS No. 96020-91-6
Batch:
Purity:97
Chemical Structure
Check the
Eflornithine (DFMO) Hydrochloride Hydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2,5-diamino-2-(difluoromethyl)pentanoic acid;hydrate;hydrochloride | |
|---|---|---|
| CAS Number | 96020-91-6 | |
| Molecular Formula |
C6H12F2N2O2.HCl.H2O |
|
| Molecular Weight (MW) | 236.64 | |
| SMILES | C(CC(C(F)F)(C(=O)O)N)CN.O.Cl | |
| InChIKey | FJPAMFNRCFEGSD-UHFFFAOYSA-N |
Eflornithine (DFMO) Hydrochloride Hydrate is a selective and irreversible inhibitor of ornithine decarboxylase (ODC) that blocks polyamine biosynthesis. By targeting ODC, it depletes intracellular polyamine levels, specifically putrescine and spermidine, thereby disrupting essential cell cycle progression and metabolic functions. This polyamine depletion ultimately leads to the suppression of cellular proliferation and inhibition of angiogenesis.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 47 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
| Water | 47 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
| Water | 47 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
| Water | 47 mg/mL |
| DMSO |
˂1 mg/mL
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | ˂1 mg/mL |
| Water | 47 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Eflornithine (DFMO) Hydrochloride Hydrate Clinical Trials
- Eflornithine (DFMO) Hydrochloride Hydrate Solubility in DMSO
- Eflornithine (DFMO) Hydrochloride Hydrate Stock Solution
- Eflornithine (DFMO) Hydrochloride Hydrate Storage
- Eflornithine (DFMO) Hydrochloride Hydrate Stability
- Eflornithine (DFMO) Hydrochloride Hydrate Molecular Weight
- Eflornithine (DFMO) Hydrochloride Hydrate SMILES
- Eflornithine (DFMO) Hydrochloride Hydrate Chemical Structure (2D and 3D)
- Eflornithine (DFMO) Hydrochloride Hydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.