CAS No. 1229194-11-9
Batch:
Purity:99.94
Chemical Structure
Check the
Edoxaban tosylate Monohydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N'-(5-chloro-2-pyridinyl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide;4-methylbenzenesulfonic acid;hydrate | |
|---|---|---|
| CAS Number | 1229194-11-9 | |
| Molecular Formula |
C24H30ClN7O4S.C7H8O3S.H2O |
|
| Molecular Weight (MW) | 738.27 | |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.CN1CCC2=C(C1)SC(=N2)C(=O)NC3CC(CCC3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C.O | |
| InChIKey | PSMMNJNZVZZNOI-SJILXJHISA-N |
Edoxaban (DU-176b) is an orally active, selective factor Xa inhibitor with a Ki of 0.561 nM, displaying greater than 10,000-fold selectivity over thrombin and factor IXa. By directly inhibiting factor Xa within the blood coagulation cascade, Edoxaban suppresses thrombin generation, prolongs clotting times, and prevents fibrin clot formation, ultimately reducing venous and arterial thrombosis. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(135.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Edoxaban tosylate Monohydrate Clinical Trials
- Edoxaban tosylate Monohydrate Solubility in DMSO
- Edoxaban tosylate Monohydrate Stock Solution
- Edoxaban tosylate Monohydrate Storage
- Edoxaban tosylate Monohydrate Stability
- Edoxaban tosylate Monohydrate Molecular Weight
- Edoxaban tosylate Monohydrate SMILES
- Edoxaban tosylate Monohydrate Chemical Structure (2D and 3D)
- Edoxaban tosylate Monohydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.