Dynasore: Selectivity & Specificity

Dynasore is a potent inhibitor of Dynamin-1 (83500 nM), Dynamin, DRP1, DYN2, SNCA, MAPT, Endocytosis, Mitochondrial fission, Endocytic vesicles, Cholesterol, Lipid rafts, TFRC, LDLR, V-ATPase, LDL, Membrane ruffling, F-actin, Pyolysin, Streptolysin-O, Subtilase cytotoxin, Inflammatory cytokine response. Dynasore exhibits the greatest inhibitory potency toward Dynamin-1 (IC50 = 83500 nM).