CAS No. 23651-95-8
Batch:
Purity:99.20
Chemical Structure
Check the
Droxidopa
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid | |
|---|---|---|
| CAS Number | 23651-95-8 | |
| Molecular Formula |
C9H11NO5 |
|
| Molecular Weight (MW) | 213.19 | |
| SMILES | C1=CC(=C(C=C1C(C(C(=O)O)N)O)O)O | |
| InChIKey | QXWYKJLNLSIPIN-JGVFFNPUSA-N |
Droxidopa is a synthetic amino acid analog and prodrug that serves as a precursor to norepinephrine and epinephrine. Upon enzymatic conversion by aromatic L-amino acid decarboxylase, droxidopa elevates central and peripheral norepinephrine concentrations. This metabolic conversion restores catecholamine signaling and stimulates vascular alpha-adrenergic pathways to restore neurotransmitter homeostasis and elevate vascular tone. [1]
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
2 mg/mL
(9.38 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | 2 mg/mL |
| Ethanol | Insoluble |
| 5%TFA | 5.03 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| DMSO |
2 mg/mL
(9.38 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | 1 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.