Clinical Trials
Numerous clinical trials, spanning Early Phase 1 through Phase 4 as well as non-interventional studies, evaluate doxycycline for bacterial sexually transmitted infections, post-exposure prophylaxis, genital Chlamydia trachomatis, ocular adnexal marginal zone lymphoma, emphysema in HIV-positive patients, Parkinson's, and Alzheimer's disease. Sponsored by academic medical centers, non-profit entities, and governmental institutions—including the Centers for Disease Control and Prevention, the National Heart, Lung, and Blood Institute, and Assistance Publique - Hôpitaux de Paris—these global studies report recruitment statuses ranging from completed and actively recruiting to not yet recruiting, terminated, and withdrawn.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07485010 | NOT_YET_RECRUITING | Mycobacterium Abscessus Pulmonary Disease; Mycobacterium Abscessus Infection; Non-Tuberculous Mycobacterial (NTM) Infections; Non-Tuberculous Mycobacteria Pulmonary Disease |
The University of Queensland |
2027-04 | PHASE2 |
| NCT07704957 | NOT_YET_RECRUITING | Chlamydia Females; Gonorrhea Female; Syphilis Female; Adherence; Prophylaxis; Prevention |
Tulane University |
2027-01-01 | PHASE4 |
| NCT07488949 | RECRUITING | Chronic Endometritis |
Fang Wang |
2024-04-09 | |
| NCT07164131 | RECRUITING | Community-acquired Pneumonia |
Mayo Clinic |
2025-09-15 | PHASE4 |
| NCT05473520 | RECRUITING | Tuberculosis; Acute Coronary Syndrome; Pulmonary Hypertension (Diagnosis) |
National University Hospital, Singapore |
2023-05-24 | PHASE3 |
| NCT07658976 | NOT_YET_RECRUITING | HIV Infection; Sexually Transmitted Infection |
HIV Prevention Trials Network |
2026-09-01 | PHASE3 |
| NCT07629167 | NOT_YET_RECRUITING | Acneiform Drug Eruption; Acneiform Eruptions |
University of California, San Francisco |
2026-08-30 | PHASE2 |
| NCT04310930 | RECRUITING | Pulmonary Disease Due to Mycobacteria (Diagnosis) |
The University of Queensland |
2020-03-02 | PHASE2; PHASE3 |
| NCT07215325 | RECRUITING | Sexually Transmitted Infections (STI) |
Emory University |
2025-10-13 | PHASE4 |
| NCT07510048 | NOT_YET_RECRUITING | HIV; STIs; STIs Prevention; HIV Prevention |
Westat |
2026-07-20 | PHASE2 |
| NCT07306234 | NOT_YET_RECRUITING | Mycoplasma Pneumoniae; Mycoplasma Pneumoniae Pneumonia |
Young June Choe |
2026-03-01 | PHASE4 |
| NCT03462329 | RECRUITING | Erythema Migrans |
University Medical Centre Ljubljana |
2018-06-01 | |
| NCT06468462 | RECRUITING | Gonorrhea Male; Chlamydia (Male); Syphilis Male |
University of Washington |
2025-10-29 | PHASE4 |
| NCT06414408 | RECRUITING | Sexually Transmitted Diseases, Bacterial |
University of California, San Francisco |
2024-10-18 | EARLY_PHASE1 |
| NCT06452394 | RECRUITING | Breast Cancer |
Swiss Cancer Institute |
2025-07-16 | PHASE2 |
| NCT06738407 | RECRUITING | Gonorrhea; Chlamydia; Syphilis; Sexually Transmitted Infections (STIs) |
Westat |
2026-02-27 | PHASE4 |
| NCT05268120 | RECRUITING | MRSA |
Leiden University Medical Center |
2022-07-25 | |
| NCT03956446 | RECRUITING | Tick Borne Encephalitis |
University Medical Centre Ljubljana |
2014-09-01 | |
| NCT05100654 | ACTIVE_NOT_RECRUITING | Erectile Dysfunction; Penile Prosthesis Infection |
University of Chicago |
2022-04-22 | EARLY_PHASE1 |
| NCT03337932 | RECRUITING | Erythema Chronicum Migrans |
University Medical Centre Ljubljana |
2018-05-01 | |
| NCT06069141 | RECRUITING | Early Syphilis, Latent, Serological Relapse After Treatment |
National Taiwan University Hospital |
2024-01-01 | |
| NCT06188442 | ACTIVE_NOT_RECRUITING | Sexually Transmitted Diseases, Bacterial; Syphilis; Gonorrhea; Chlamydia |
Chinese University of Hong Kong |
2025-03-29 | PHASE4 |
| NCT07779629 | NOT_YET_RECRUITING | Brucellosis; Osteoarthritis |
The First Affiliated Hospital of Shihezi University |
2026-09-01 | |
| NCT07230028 | NOT_YET_RECRUITING | Lyme Borreliosis, Nervous System |
Radboud University Medical Center |
2027-03-01 | PHASE4 |
| NCT07767422 | NOT_YET_RECRUITING | Lymphogranuloma Venereum; no Anorectal Symptoms; Doxycycline |
University Hospital, Bordeaux |
2026-09 | PHASE2 |
| NCT06446245 | RECRUITING | Tuberculosis, Meningeal; Tuberculosis; Meningitis (Etiology); Tuberculosis, Central Nervous System; Tuberculosis; Meningoencephalitis (Etiology) |
National University Hospital, Singapore |
2025-08-21 | PHASE2 |
| NCT07500415 | RECRUITING | Sexually Transmitted Diseases; Syphilis; Gonorrhea; Chlamydia Infections; HIV Infections |
Oswaldo Cruz Foundation |
2025-10-28 | |
| NCT07688096 | NOT_YET_RECRUITING | Ehlers-Danlos Syndrome Hypermobility Type (hEDS); Ehlers-Danlos Syndrome (EDS); Joint Hypermobility; Joint Instability; Hypermobility Spectrum Disorder; Chronic Pain Syndrome; Musculoskeletal Pain; Sprain; Subluxation; Dislocation; Craniocervical Disfunction |
Manhattan Pain Medicine, PLLC |
2026-07-15 | PHASE1; PHASE2 |
| NCT04108897 | ACTIVE_NOT_RECRUITING | Rosacea |
Johns Hopkins University |
2019-09-17 | EARLY_PHASE1 |
| NCT07755618 | NOT_YET_RECRUITING | Sexually Transmitted Infection |
HIV Prevention Trials Network |
2026-08-01 | PHASE1 |
| NCT07343635 | RECRUITING | Erythematotelangiectatic Rosacea |
The Fourth Affiliated Hospital of Zhejiang University School of Medicine |
2026-02-01 | |
| NCT07634341 | NOT_YET_RECRUITING | Chronic Periodontitis |
Fayoum University |
2026-06 | PHASE4 |
| NCT07024654 | WITHDRAWN | Chronic Knee Pain; Osteoarthritis |
Campbell Clinic |
2026-06 | PHASE2 |
| NCT06120140 | ACTIVE_NOT_RECRUITING | Carcinoma, Non-Small-Cell Lung |
Janssen Research & Development, LLC |
2024-02-16 | PHASE2 |
| NCT07498010 | RECRUITING | Seroma |
University of Miami |
2026-05-31 | PHASE2 |
| NCT07544251 | RECRUITING | Acne Vulgaris |
Integrative Skin Science and Research |
2026-04-20 | PHASE4 |
| NCT05382208 | ACTIVE_NOT_RECRUITING | Emphysema; HIV |
Weill Medical College of Cornell University |
2022-08-22 | PHASE2 |
| NCT01631617 | RECRUITING | Eczema; Dermatitis; Skin Diseases, Genetic; Dermatitis, Atopic; Skin Diseases |
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) |
2012-09-18 | PHASE2 |
| NCT04297592 | ENROLLING_BY_INVITATION | Infections Joint Prosthetic; Overweight or Obesity; MSSA Colonization; MRSA; Chronic Kidney Diseases; Diabetes; Autoimmune Diseases; Inflammatory Disease; Tobacco Use |
Mayo Clinic |
2020-06-11 | PHASE4 |
| NCT02713607 | ACTIVE_NOT_RECRUITING | Acne Vulgaris |
University of California, Davis |
2016-03 | PHASE1; PHASE2 |
| NCT04762134 | RECRUITING | Bacterial Sexually Transmitted Diseases |
Jonathan Troy Grennan |
2023-06-02 | |
| NCT04504123 | RECRUITING | Exudative Macular Degeneration; Wet Age-related Macular Degeneration |
University of Iowa |
2020-11-04 | PHASE2 |
| NCT06477185 | RECRUITING | Tuberculosis, Pulmonary |
Makerere University |
2024-12-04 | PHASE2 |
| NCT07180563 | RECRUITING | Chronic Endometritis |
The Fourth Affiliated Hospital of Zhejiang University School of Medicine |
2025-03-15 | PHASE1; PHASE2 |
| NCT03083197 | ACTIVE_NOT_RECRUITING | Scrub Typhus |
University of Oxford |
2017-10-15 | PHASE4 |
| NCT06045481 | NOT_YET_RECRUITING | Relapsing Fever, Tick-Borne |
Medical Corps, Israel Defense Force |
2024-08-01 | |
| NCT07397403 | RECRUITING | Syphilis Infection; Gonorrhea; Chlamydia |
Bangrak STIs Center |
2025-10-06 | PHASE4 |
| NCT03435952 | ACTIVE_NOT_RECRUITING | Malignant Neoplasm of Breast; Malignant Neoplasms of Digestive Organs; Malignant Neoplasms of Eye Brain and Other Parts of Central Nervous System; Malignant Neoplasms of Female Genital Organs; Malignant Neoplasms of Ill-defined Secondary and Unspecified Sites; Malignant Neoplasms of Independent (Primary) Multiple Sites; Malignant Neoplasms of Lip Oral Cavity and Pharynx; Malignant Neoplasms of Male Genital Organs; Malignant Neoplasms of Mesothelial and Soft Tissue; Malignant Neoplasms of Respiratory and Intrathoracic Organs; Malignant Neoplasms of Thyroid and Other Endocrine Glands; Malignant Neoplasms of Urinary Tract |
M.D. Anderson Cancer Center |
2018-07-10 | PHASE1 |
| NCT05521048 | ACTIVE_NOT_RECRUITING | Neurofibromatosis Type 2 |
Massachusetts Eye and Ear Infirmary |
2022-09-19 | PHASE1; PHASE2 |
| NCT06616168 | ACTIVE_NOT_RECRUITING | Bacterial Vaginosis |
Danylo Halytsky Lviv National Medical University |
2023-09-01 | PHASE1 |
| NCT07320001 | NOT_YET_RECRUITING | Lymphatic Abnormality |
Basharat Hussain |
2026-01-26 | PHASE2 |
| NCT06809829 | RECRUITING | Immediate Implant Placement |
Kafrelsheikh University |
2025-02 | |
| NCT05061732 | UNKNOWN | Helicobacter Pylori Infection |
Shanghai Zhongshan Hospital |
2021-09-30 | PHASE4 |
| NCT06683638 | RECRUITING | Syphilis |
University of Washington |
2025-03-03 | PHASE2 |
| NCT06329882 | RECRUITING | Diabetes Mellitus, Type 2 |
Mostafa Bahaa |
2024-03-30 | PHASE1; PHASE2 |
| NCT04582383 | ACTIVE_NOT_RECRUITING | Acne |
University of Pennsylvania |
2022-03-30 | PHASE4 |
| NCT05840159 | COMPLETED | Chlamydial Infection |
National Institute of Allergy and Infectious Diseases (NIAID) |
2024-01-19 | PHASE4 |
| NCT01917721 | ACTIVE_NOT_RECRUITING | Kawasaki Disease; Coronary Aneurysm |
Hawaii Pacific Health |
2013-10 | PHASE2 |
| NCT06412588 | COMPLETED | Helicobacter Pylori Infection |
Nanjing First Hospital, Nanjing Medical University |
2024-06-15 | |
| NCT05398055 | UNKNOWN | Rocky Mountain Spotted Fever |
Hospital General de Mexicali |
2022-05-12 | PHASE3 |
| NCT05112211 | RECRUITING | Thyroid Associated Ophthalmopathy |
Sun Yat-sen University |
2022-01-01 | |
| NCT05874570 | RECRUITING | Helicobacter Pylori Infection |
Shanghai Jiao Tong University School of Medicine |
2023-06-20 | PHASE4 |
| NCT04686799 | COMPLETED | Lateral Epicondylitis; Lateral Epicondylitis, Left Elbow; Lateral Epicondylitis, Right Elbow; Lateral Epicondylitis, Unspecified Elbow; Lateral Epicondylitis (Tennis Elbow) Bilateral; Medial Epicondylitis; Medial Epicondylitis, Right Elbow; Medial Epicondylitis, Left Elbow |
Hospital for Special Surgery, New York |
2020-12-03 | PHASE1 |
| NCT05972772 | RECRUITING | Infectious Disease; Therapeutics |
Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit |
2024-11-01 | PHASE2; PHASE3 |
| NCT07357337 | COMPLETED | Acne Vulgaris on the Face; Acne Vulgaris |
Ghurki Trust and Teaching Hospital |
2025-02-15 | PHASE4 |
| NCT06994455 | UNKNOWN | Periodontitis |
Mansoura University |
2024-06-02 | |
| NCT06915688 | NOT_YET_RECRUITING | COPD |
Amina Aslam |
2025-04-15 | |
| NCT03508232 | COMPLETED | ST Segment Elevation Myocardial Infarction; Heart Failure |
University of Alberta |
2020-01-06 | PHASE2 |
| NCT05980871 | TERMINATED | Early Syphilis |
National Taiwan University Hospital |
2023-03-10 | PHASE4 |
| NCT04838717 | COMPLETED | Syphilis |
Assistance Publique - Hôpitaux de Paris |
2021-12-06 | PHASE3 |
| NCT05296837 | COMPLETED | Ocular Rosacea; Antimicrobial Resistance |
University of California, San Francisco |
2023-06-22 | PHASE4 |
| NCT06582966 | COMPLETED | STI |
University of Washington |
2024-08-13 | PHASE4 |
| NCT06545656 | COMPLETED | Sexually Transmitted Infection |
Emory University |
2024-09-13 | PHASE4 |
| NCT06007534 | UNKNOWN | Post-exposure Prophylaxis; Sexually Transmitted Diseases; Doxycycline |
Assistance Publique - Hôpitaux de Paris |
2023-10-25 | |
| NCT05977868 | TERMINATED | Endovascular Infection; Bone and Joint Infection; Skin and Soft Tissue Infection; Pulmonary Infection; Gastrointestinal Infection; Genitourinary Infection |
West Virginia University |
2023-08-04 | PHASE4 |
| NCT06422221 | UNKNOWN | Bacteremia; Endocarditis |
University of Santiago de Compostela |
2024-07-15 | PHASE4 |
| NCT07513103 | COMPLETED | Scrub Typhus |
Jin Soo Lee |
2022-11-19 | |
| NCT05853120 | COMPLETED | Sexually Transmitted Diseases |
Emory University |
2023-05-31 | PHASE4 |
| NCT07385300 | COMPLETED | Periodontitis; Diabete Mellitus |
Alexandria University |
2023-08-20 | |
| NCT05878353 | COMPLETED | Periodontal Diseases |
University of Turin, Italy |
2023-05-30 | |
| NCT05897034 | NOT_YET_RECRUITING | Sexually Transmitted Diseases |
Tanta University |
2023-06-20 | PHASE2; PHASE3 |
| NCT07064278 | COMPLETED | Refractory Mycoplasma Pneumoniae Pneumonia |
Children's Hospital of Hebei Province |
2022-12-01 | |
| NCT02864550 | COMPLETED | Syphilis; Sexually Transmitted Infections |
British Columbia Centre for Disease Control |
2019-08-15 | PHASE4 |
| NCT05972772 | Not yet recruiting | Infectious Disease|Therapeutics |
Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit|Mahidol Oxford Tropical Medicine Research Unit |
2024-03-20 | Phase 2|Phase 3 |
| NCT06252194 | UNKNOWN | Acne Vulgaris |
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
2023-03-05 | PHASE2 |
| NCT06172686 | UNKNOWN | Controlled Human Malaria Infection; Induced Blood Stage Malaria Infection; Malaria Transmission; Malaria Challenge |
Ifakara Health Institute |
2024-01-09 | PHASE1 |
| NCT03637400 | COMPLETED | Methicillin-resistant Staphylococcus Aureus; Skin Infection |
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center |
2018-11-26 | PHASE2 |
| NCT06570863 | COMPLETED | Periodontitis; Adult |
Dr fizza khalid |
2022-07-01 | |
| NCT04626193 | UNKNOWN | Helicobacter Pylori Infection |
Damascus Hospital |
2020-10-31 | PHASE4 |
| NCT05708625 | UNKNOWN | Leishmaniasis, Cutaneous |
Zagazig University |
2022-01-01 | PHASE3 |
| NCT05111002 | TERMINATED | Mycoplasma Genitalium Infection |
University of Washington |
2022-04-22 | PHASE1; PHASE2 |
| NCT06007534 | Recruiting | Post-exposure Prophylaxis|Sexually Transmitted Diseases|Doxycycline |
Assistance Publique - Hôpitaux de Paris |
2023-10-25 | Not Applicable |
| NCT05157412 | COMPLETED | Nasal Polyps; Chronic Rhinosinusitis With Nasal Polyps |
Assiut University |
2021-07-01 | PHASE3 |
| NCT05875506 | COMPLETED | Osteitis; Dry Socket |
Minia University |
2023-05-01 | |
| NCT05296629 | COMPLETED | Papulopustular Rosacea |
Journey Medical Corporation |
2022-03-14 | PHASE3 |
| NCT05431673 | UNKNOWN | Rhinoscleroma |
Assiut University |
2022-08-21 | PHASE1 |
| NCT05343455 | COMPLETED | Papulopustular Rosacea |
Journey Medical Corporation |
2022-03-29 | PHASE3 |
| NCT03980223 | COMPLETED | Gonorrhea; Chlamydia; Syphilis |
University of California, San Francisco |
2019-11-26 | PHASE4 |
| NCT04762134 | Recruiting | Bacterial Sexually Transmitted Diseases |
Jonathan Troy Grennan|Canadian Institutes of Health Research (CIHR)|British Columbia Centre for Disease Control |
2023-06-02 | Phase 4 |
| NCT05853120 | Recruiting | Sexually Transmitted Diseases |
Emory University|Centers for Disease Control and Prevention |
2023-05-31 | Phase 4 |
| NCT06199440 | COMPLETED | Periodontal Diseases; Type 2 Diabetes |
King Abdulaziz University |
2022-06-01 | PHASE1; PHASE2 |
| NCT04597424 | COMPLETED | Unsafe Sex; Risk-Taking |
ANRS, Emerging Infectious Diseases |
2021-01-19 | PHASE3 |
| NCT03334682 | COMPLETED | Acne Vulgaris |
Nantes University Hospital |
2018-01-31 | PHASE3 |
| NCT04723940 | UNKNOWN | Joint Infection |
Rothman Institute Orthopaedics |
2021-01-25 | PHASE3 |
| NCT03481972 | COMPLETED | TTR Cardiac Amyloidosis |
Fondazione IRCCS Policlinico San Matteo di Pavia |
2018-04-11 | PHASE3 |
| NCT05492019 | UNKNOWN | Parkinson Disease |
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
2022-07-01 | PHASE2 |
| NCT03911440 | UNKNOWN | Atypical Pneumonia |
National Taiwan University Hospital |
2018-11-10 | |
| NCT05018923 | UNKNOWN | Helicobacter Pylori Infection |
Shanghai Zhongshan Hospital |
2021-08-24 | PHASE4 |
| NCT05410223 | UNKNOWN | Helicobacter Pylori Infection |
The Third Xiangya Hospital of Central South University |
2021-04-06 | |
| NCT04864717 | UNKNOWN | Acneiform Eruptions; Cancer, Treatment-Related |
Lady Davis Institute |
2021-09-01 | PHASE4 |
| NCT04234945 | UNKNOWN | Infertility, Female; Pelvic Inflammatory Disease |
Ahmadu Bello University Teaching Hospital |
2020-01-13 | |
| NCT04050540 | COMPLETED | HIV Infections; HIV/AIDS; Neisseria Gonorrheae Infection; Chlamydia Trachomatis Infection; Syphilis Infection |
University of Washington |
2020-02-05 | PHASE4 |
| NCT05401422 | UNKNOWN | Rosacea |
Cairo University |
2022-05-25 | |
| NCT03162497 | COMPLETED | Dry Eye Syndromes; Meibomian Gland Dysfunction |
Medical University of Vienna |
2018-01-08 | PHASE4 |
| NCT05382208 | Recruiting | Emphysema|HIV |
Weill Medical College of Cornell University|National Heart Lung and Blood Institute (NHLBI)|University of California Los Angeles|University of Iowa|University of Michigan |
2022-08-22 | Phase 2 |
| NCT02203682 | UNKNOWN | Graves Ophthalmopathy; Graves Disease; Thyroid-associated Ophthalmopathy; Thyroid Diseases; Endocrine System Diseases; Eye Diseases, Hereditary; Hyperthyroidism; Autoimmune Diseases; Immune System Diseases |
Sun Yat-sen University |
2014-07 | PHASE2 |
| NCT05492019 | Recruiting | Parkinson Disease |
Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh |
2022-07-01 | Phase 2 |
| NCT06090565 | COMPLETED | Gonorrhea |
Bulovka Hospital |
2021-04-01 | PHASE4 |
| NCT05097846 | UNKNOWN | Helicobacter Pylori Infection |
wang xiaoyan |
2021-06-17 | |
| NCT03474458 | TERMINATED | Cardiac AL Amyloidosis |
Fondazione IRCCS Policlinico San Matteo di Pavia |
2019-02-11 | PHASE2; PHASE3 |
| NCT03986996 | TERMINATED | Ulcerative Colitis |
Wolfson Medical Center |
2019-07-25 | PHASE2 |
| NCT04482686 | COMPLETED | COVID; Covid-19; Corona Virus Infection; Coronavirus Infection; Coronavirus-19; SARS-CoV2; SARS-CoV Infection |
ProgenaBiome |
2020-12-09 | PHASE1 |
| NCT03968562 | UNKNOWN | Hives |
State University of New York - Downstate Medical Center |
2019-05-15 | PHASE2 |
| NCT04860505 | COMPLETED | Sexually Transmitted Diseases |
Emory University |
2021-05-20 | PHASE4 |
| NCT05191875 | COMPLETED | Helicobacter Pylori Infection |
The Third Xiangya Hospital of Central South University |
2021-12-01 | |
| NCT05216744 | COMPLETED | Neisseria Gonorrhoeae Infection; Chlamydia Trachomatis Infection |
Haiphong University of Medicine and Pharmacy |
2021-07-15 | PHASE2 |
| NCT03479502 | COMPLETED | Adhesive Capsulitis; Adhesive Capsulitis of Unspecified Shoulder; Frozen Shoulder |
Vanderbilt University Medical Center |
2018-03-05 | PHASE4 |
| NCT01411202 | UNKNOWN | Malignant Pleural Effusion |
Ottawa Hospital Research Institute |
2011-06 | PHASE2 |
| NCT03530319 | UNKNOWN | Pneumonia, Mycoplasma |
National Taiwan University Hospital |
2018-11-10 | |
| NCT04729140 | UNKNOWN | Covid19 |
Max Health, Subsero Health |
2020-12-28 | PHASE4 |
| NCT05399290 | COMPLETED | Acne Vulgaris; Pediatrics |
Michigan State University |
2020-11-19 | PHASE4 |
| NCT03173053 | TERMINATED | Staphylococcus Aureus; Motility Disorder |
Radboud University Medical Center |
2018-02-08 | |
| NCT05545462 | COMPLETED | Umbilical Granuloma |
Shaheed Zulfiqar Ali Bhutto Medical University |
2020-10-01 | |
| NCT04636125 | UNKNOWN | Periprosthetic Infection; Oral Antibiotics; Revision Total Shoulder Arthroplasty |
Rothman Institute Orthopaedics |
2019-09-24 | PHASE3 |
| NCT03655197 | COMPLETED | Rosacea; Ocular Rosacea; Cutaneous Rosacea |
University of California, Davis |
2017-11-02 | EARLY_PHASE1 |
| NCT02929121 | COMPLETED | Lymphedema; Lymphatic Filariasis; Filariasis |
The Task Force for Global Health |
2019-01-15 | PHASE3 |
| NCT04167085 | COMPLETED | Epistaxis |
University of California, Los Angeles |
2017-12-18 | PHASE4 |
| NCT04715295 | UNKNOWN | COVID-19 |
Yaounde Central Hospital |
2020-10-05 | PHASE4 |
| NCT04451330 | COMPLETED | Acne Vulgaris |
Galderma R&D |
2020-07-29 | PHASE4 |
| NCT04433078 | WITHDRAWN | Cytokine Storm; SARS-CoV-2 |
Temple University |
2020-06-22 | PHASE2 |
| NCT04846335 | COMPLETED | Familial Fatal Insomnia |
Mario Negri Institute for Pharmacological Research |
2011-04-28 | PHASE2 |
| NCT03397004 | COMPLETED | Hereditary Hemorrhagic Telangiectasia (HHT) |
Unity Health Toronto |
2018-09-12 | PHASE2 |
| NCT02341209 | TERMINATED | Cutaneous T-cell Lymphoma; Mycosis Fungoides; Sezary Syndrome |
Rochester General Hospital |
2018-02-06 | PHASE2 |
| NCT04371952 | WITHDRAWN | COVID19 |
Nantes University Hospital |
2021-02-01 | PHASE3 |
| NCT04584567 | COMPLETED | Covid19 |
Hedi Gharsallah |
2020-11-20 | PHASE3 |
| NCT02606032 | COMPLETED | Ulcerative Colitis |
Hamilton Health Sciences Corporation |
2016-05 | PHASE2 |
| NCT02583282 | COMPLETED | Malignant Pleural Effusion |
Post Graduate Institute of Medical Education and Research, Chandigarh |
2015-08-01 | |
| NCT03401372 | COMPLETED | Amyloidosis; Systemic |
Jian Li |
2018-04-21 | |
| NCT03116659 | UNKNOWN | Lymphoma, T-Cell, Cutaneous |
James J. Peters Veterans Affairs Medical Center |
2018-02-01 | EARLY_PHASE1 |
| NCT02927496 | COMPLETED | Lymphedema; Lymphatic Filariasis; Filariasis |
The Task Force for Global Health |
2018-06-19 | PHASE3 |
| NCT02874430 | TERMINATED | Breast Carcinoma; Endometrial Clear Cell Adenocarcinoma; Endometrial Serous Adenocarcinoma; Uterine Corpus Cancer; Uterine Corpus Carcinosarcoma |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2016-06-08 | PHASE2 |
| NCT03322488 | UNKNOWN | Perianal Fistula; Crohn Disease |
University of Zurich |
2017-06-20 | |
| NCT03618108 | TERMINATED | Coronary Heart Disease; Chlamydophila Pneumoniae Infections |
Cadrock Pty. Ltd. |
2018-04-04 | PHASE2 |
| NCT04551755 | UNKNOWN | Covid19 |
Bangladesh Medical Research Council (BMRC) |
2020-09 | PHASE2 |
| NCT04407130 | COMPLETED | COVID-19 Patients |
International Centre for Diarrhoeal Disease Research, Bangladesh |
2020-06-16 | PHASE2 |
| NCT04591600 | COMPLETED | Covid19 |
Alkarkh Health Directorate-Baghdad |
2020-07-01 | PHASE1; PHASE2 |
| NCT04370782 | COMPLETED | COVID-19 |
St. Francis Hospital, New York |
2020-04-28 | PHASE4 |
| NCT04349410 | COMPLETED | CoVid 19 Positive |
The Camelot Foundation |
2020-04-11 | PHASE2; PHASE3 |
| NCT02463942 | UNKNOWN | Tick-borne Encephalitis |
University Medical Centre Ljubljana |
2014-09 | |
| NCT02553083 | UNKNOWN | Bacterial Infection Due to Helicobacter Pylori (H. Pylori) |
Rabin Medical Center |
2015-10-22 | PHASE4 |
| NCT04348786 | COMPLETED | Helicobacter Pylori Infection |
Damascus Hospital |
2019-02-01 | PHASE4 |
| NCT04523831 | COMPLETED | Covid19 |
Dhaka Medical College |
2020-06-01 | PHASE3 |
| NCT03532464 | COMPLETED | Chlamydia Trachomatis Infection; Vaginal Infection; Anal Infection |
University Hospital, Bordeaux |
2018-10-10 | PHASE4 |
| NCT04239755 | COMPLETED | Traumatic Brain Injury |
Damanhour University |
2020-02-01 | PHASE4 |
| NCT04528927 | WITHDRAWN | COVID 19; Patients Hospitalized |
Abderrahmane Mami Hospital |
2020-05-15 | PHASE3 |
| NCT04125706 | UNKNOWN | Periodontitis |
Riyadh Elm University |
2019-11-01 | |
| NCT02147262 | UNKNOWN | Chronic Atrophic Acrodermatitis |
University Medical Centre Ljubljana |
2013-07 | |
| NCT02929134 | COMPLETED | Lymphedema; Lymphatic Filariasis; Filariasis |
The Task Force for Global Health |
2018-02-16 | PHASE3 |
| NCT02844634 | COMPLETED | HIV; Syphilis |
British Columbia Centre for Disease Control |
2018-05-15 | PHASE4 |
| NCT03448731 | COMPLETED | Skin Toxicity |
Fundacion CRIS de Investigación para Vencer el Cáncer |
2018-05-10 | PHASE2 |
| NCT02850913 | UNKNOWN | Seizures |
Makerere University |
2016-09-05 | PHASE2 |
| NCT02759120 | TERMINATED | Idiopathic Pulmonary Fibrosis |
Weill Medical College of Cornell University |
2017-03-22 | PHASE3 |
| NCT04067011 | COMPLETED | Anthrax |
Emergent BioSolutions |
2019-08-12 | PHASE2 |
| NCT03608774 | COMPLETED | Anal Chlamydia Infection |
National Institute of Allergy and Infectious Diseases (NIAID) |
2018-07-13 | PHASE4 |
| NCT03194204 | COMPLETED | Rheumatoid Arthritis |
Assiut University |
2019-10-01 | |
| NCT02553473 | COMPLETED | Neuroborreliosis, Borrelia Burgdorferi |
Sorlandet Hospital HF |
2015-10 | PHASE3 |
| NCT03956212 | COMPLETED | Erythema Migrans |
University Medical Centre Ljubljana |
2017-06-01 | |
| NCT01438515 | COMPLETED | Methicillin-resistant Staphylococcus Aureus |
Horizon Health Network |
2008-08 | |
| NCT03153267 | COMPLETED | Erythema Chronicum Migrans |
University Medical Centre Ljubljana |
2017-06-01 | |
| NCT01658995 | COMPLETED | ESI-related Bleeding |
Petra M. Casey |
2012-09-13 | PHASE3 |
| NCT03824340 | UNKNOWN | Infertility |
Aljazeera Hospital |
2019-01-30 | |
| NCT03960411 | UNKNOWN | ST Elevation Myocardial Infarction; Anterior Wall Myocardial Infarction; Heart Failure; Remodeling, Ventricular |
Felix Chikita Fredy, MD |
2019-05-25 | PHASE3 |
| NCT01756833 | COMPLETED | Aneurysm |
University of Maryland, Baltimore |
2013-05 | PHASE2 |
| NCT03342456 | COMPLETED | Duodenal Ulcer Due to Helicobacter Pylori |
The Third Xiangya Hospital of Central South University |
2017-12-13 | PHASE4 |
| NCT01783106 | COMPLETED | Crohn's Disease |
Royal Liverpool University Hospital |
2014-02-01 | PHASE2 |
| NCT02456662 | COMPLETED | Drug-induced Nausea and Vomiting |
University of Rochester |
2015-10-07 | |
| NCT03454945 | UNKNOWN | Lymphoma |
Cairo University |
2017-03-01 | PHASE3 |
| NCT02913118 | UNKNOWN | Community Acquired Pneumonia |
Qingfeng Pharmaceutical Group |
2016-07 | PHASE4 |
| NCT03076281 | TERMINATED | Larynx; LIP; Oral Cavity; Pharynx |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2017-04-03 | PHASE2 |
| NCT02910011 | COMPLETED | Dermatitis, Atopic |
University of Florida |
2017-05-18 | PHASE2 |
| NCT03340961 | COMPLETED | Rosacea |
Dr. Reddy's Laboratories Limited |
2017-10-01 | PHASE2 |
| NCT03457636 | COMPLETED | Acne |
Derm Research, PLLC |
2018-03-19 | PHASE4 |
| NCT02894268 | UNKNOWN | Helicobacter Pylori Infection |
Sir Run Run Shaw Hospital |
2016-02 | PHASE4 |
| NCT02775695 | COMPLETED | Resectable Pancreatic Cancer |
Medical College of Wisconsin |
2017-04-03 | PHASE2 |
| NCT02564471 | COMPLETED | Rabies |
State University of New York - Upstate Medical University |
2016-11-11 | PHASE4 |
| NCT01874860 | COMPLETED | Colorectal Cancer; Head and Neck Cancer |
University of Louisville |
2013-08 | PHASE2 |
| NCT02204254 | COMPLETED | Rosacea |
Centre Hospitalier Universitaire de Nice |
2014-03 | |
| NCT03075891 | COMPLETED | Rosacea |
Galderma R&D |
2017-07-05 | PHASE4 |
| NCT01635530 | COMPLETED | Lyme Neuroborreliosis |
Turku University Hospital |
2012-08 | PHASE4 |
| NCT01594827 | COMPLETED | Cystic Fibrosis |
Johns Hopkins University |
2012-10 | PHASE2 |
| NCT03237533 | UNKNOWN | Oral Lichen Planus |
University of Faisalabad |
2017-06-01 | EARLY_PHASE1 |
| NCT02753426 | COMPLETED | Chronic Kidney Disease; Cardiorenal Syndrome |
University of California, San Francisco |
2016-04 | PHASE1 |
| NCT01847976 | COMPLETED | Pain |
Ottawa Hospital Research Institute |
2013-08 | PHASE2 |
| NCT01163994 | UNKNOWN | Multiple Erythema Migrans |
University Medical Centre Ljubljana |
2010-06 | |
| NCT02207556 | COMPLETED | Primary Systemic Amyloidosis |
Medical College of Wisconsin |
2014-10-01 | PHASE2 |
| NCT02305940 | COMPLETED | Chronic Obstructive Pulmonary Disease (COPD) |
Imperial College London |
2014-07 | PHASE3 |
| NCT02756403 | COMPLETED | First Trimester Abortion |
Medstar Health Research Institute |
2016-03 | |
| NCT01744093 | COMPLETED | HIV; Chronic Obstructive Pulmonary Disease (COPD); Emphysema |
Weill Medical College of Cornell University |
2014-12-08 | |
| NCT02774993 | COMPLETED | Tuberculosis |
National University Hospital, Singapore |
2015-09 | PHASE2 |
| NCT02623959 | TERMINATED | Advanced Cancers; Malignant Pleural Effusions |
M.D. Anderson Cancer Center |
2016-04-27 | PHASE4 |
| NCT02899000 | COMPLETED | Acne Vulgaris |
Galderma R&D |
2016-07-29 | PHASE4 |
| NCT02281643 | COMPLETED | Mansonella Perstans Infection; Buruli Ulcer; Tuberculosis; Co-infection |
Kwame Nkrumah University of Science and Technology |
2014-10 | PHASE2 |
| NCT03115177 | COMPLETED | Osteoarthritis |
Rush University Medical Center |
2015-11 | |
| NCT02562651 | UNKNOWN | Vascular Diseases; Cardiovascular Diseases; Acute Myocardial Infarction |
Russian Academy of Medical Sciences |
2014-02 | PHASE2; PHASE3 |
| NCT03765931 | COMPLETED | Fever |
Institut de Recherche pour le Developpement |
2016-07 | PHASE4 |
| NCT02688738 | UNKNOWN | Propionibacterium |
Rothman Institute Orthopaedics |
2015-03 | |
| NCT01345526 | COMPLETED | Metastatic Colorectal Cancer |
Universitätsmedizin Mannheim |
2011-04 | PHASE2 |
| NCT02726646 | COMPLETED | Chronic Periodontitis |
University of Campinas, Brazil |
2015-06 | PHASE2 |
| NCT03478436 | COMPLETED | Rosacea |
Medical University of Vienna |
2016-07 | PHASE1 |
| NCT01317433 | TERMINATED | Colorectal Cancer Metastatic; Skin Toxicity |
Institut Cancerologie de l'Ouest |
2010-12-29 | |
| NCT01198912 | COMPLETED | Chronic Rhinosinusitis; Nasal Polyps |
University Hospital, Ghent |
2011-11-22 | PHASE2 |
| NCT02569437 | TERMINATED | Polyp of Nasal Sinus |
Icahn School of Medicine at Mount Sinai |
2014-09 | PHASE2 |
| NCT03585140 | COMPLETED | Acne Vulgaris; Diet Modification |
Centro Dermatológico Dr. Ladislao de la Pascua |
2016-01-01 | |
| NCT02388477 | WITHDRAWN | Rotator Cuff Injury |
Milton S. Hershey Medical Center |
||
| NCT01820910 | COMPLETED | Marginal Zone Lymphoma of Ocular Adnexal |
International Extranodal Lymphoma Study Group (IELSG) |
2013-03-19 | PHASE2 |
| NCT02735837 | COMPLETED | Diabetes Mellitus With Periodontal Disease |
Amirhossein Farahmand |
2015-01 | PHASE2; PHASE3 |
| NCT01809444 | UNKNOWN | Thyroid Associated Opthalmopathies |
Sun Yat-sen University |
2012-11 | PHASE2; PHASE3 |
| NCT02845024 | COMPLETED | Diabetes Mellitus With Periodontal Disease |
Islamic Azad University, Sanandaj |
2014-09 | |
| NCT02239731 | COMPLETED | Rash Due to Epidermal Growth Factor Receptor Inhibitors |
Vyne Therapeutics Inc. |
2014-10 | PHASE2 |
| NCT01949233 | UNKNOWN | Marfan Syndrome |
University of Oxford |
2013-10 | PHASE2 |
| NCT04206631 | COMPLETED | Acne Vulgaris |
Indonesia University |
2015-04-01 | PHASE1 |
| NCT01318356 | COMPLETED | Q Fever; Fatigue Syndrome, Chronic; Coxiella Infection |
Radboud University Medical Center |
2011-04 | PHASE4 |
| NCT01661985 | UNKNOWN | Urethritis; Cervicitis; Genital Mycoplasma Infection; Chlamydia Trachomatis |
Ostergotland County Council, Sweden |
2010-02 | PHASE4 |
| NCT01160640 | COMPLETED | Pelvic Inflammatory Disease |
Harold Wiesenfeld |
2010-11 | PHASE2 |
| NCT01590082 | TERMINATED | Melanoma |
M.D. Anderson Cancer Center |
2012-11 | PHASE1; PHASE2 |
| NCT02086591 | TERMINATED | Adult Diffuse Large B-Cell Lymphoma; Mantle Cell Lymphoma Recurrent; Lymphoma, Follicular; Marginal Zone B-Cell Lymphoma; Malignant Lymphoma - Lymphoplasmacytic; Waldenstrom Macroglobulinemia; Small Lymphocytic Lymphoma; Chronic Lymphocytic Leukemia (CLL); T-Cell Lymphoma |
University of Rochester |
2014-03 | PHASE2 |
| NCT01855360 | COMPLETED | Amyloidosis; Heart (Manifestation); Senile Cardiac Amyloidosis |
Brigham and Women's Hospital |
2013-06 | PHASE1; PHASE2 |
| NCT01677286 | COMPLETED | Amyloidosis |
Boston University |
2012-07 | PHASE2 |
| NCT01465802 | COMPLETED | Non Small Cell Lung Cancer (NSCLC) |
Pfizer |
2011-12-26 | PHASE2 |
| NCT01171859 | COMPLETED | Transthyretin Amyloidosis |
Fondazione IRCCS Policlinico San Matteo di Pavia |
2010-07 | PHASE2 |
| NCT01879930 | TERMINATED | Chronic Pelvic Pain Syndrome; Bladder Pain Syndrome |
Insel Gruppe AG, University Hospital Bern |
2012-11 | PHASE4 |
| NCT01668498 | COMPLETED | Ras-wildtype Colorectal Cancer |
AIO-Studien-gGmbH |
2011-05 | PHASE2 |
| NCT02036528 | TERMINATED | Diabetic Foot Ulcers |
Royer Biomedical, Inc. |
2014-01 | PHASE1; PHASE2 |
| NCT02016365 | COMPLETED | Transthyretin Amyloidosis; Cardiomyopathy |
Umeå University |
2012-02 | PHASE2 |
| NCT02487186 | COMPLETED | Periodontal Disease |
University of Campinas, Brazil |
2010-03 | PHASE4 |
| NCT02174757 | COMPLETED | Chronic Periodontitis |
CD Pharma India Pvt. Ltd. |
2014-08 | PHASE3 |
| NCT01788215 | COMPLETED | Polycystic Ovarian Syndrome (PCOS); Irregular Menstrual Cycles; Androgen Excess |
University of Rochester |
2010-11 | PHASE3 |
| NCT01886560 | UNKNOWN | Eye Burns |
Sun Yat-sen University |
2013-09 | PHASE2; PHASE3 |
| NCT01885910 | COMPLETED | Acne Vulgaris |
Derm Research, PLLC |
2013-07 | PHASE4 |
| NCT01653522 | WITHDRAWN | Migraine Disorders; Headache, Migraine; Migraine; Migraine Headache; Migraine With Aura; Migraine Without Aura; Headache Disorders, Primary |
The Cleveland Clinic |
2012-07 | |
| NCT03727620 | COMPLETED | Aggressive Periodontitis |
Mohammed V Souissi University |
2014-01-06 | PHASE1; PHASE2 |
| NCT01935622 | TERMINATED | Non-ischemic Cardiomyopathy; Systolic Heart Failure (NYHA II-III) |
Virginia Commonwealth University |
2012-07 | PHASE2 |
| NCT01825408 | COMPLETED | Sinusitis |
University of North Carolina, Chapel Hill |
2013-02 | PHASE4 |
| NCT00980148 | COMPLETED | Chlamydial Infection |
National Institute of Allergy and Infectious Diseases (NIAID) |
2009-12-02 | PHASE3 |
| NCT01867294 | COMPLETED | Advanced Malignant Neoplasm; Dermatologic Complication |
Academic and Community Cancer Research United |
2012-08-31 | PHASE2 |
| NCT02884713 | COMPLETED | GASTRITIS |
King Faisal Specialist Hospital & Research Center |
2013-06 | |
| NCT02538224 | COMPLETED | Chronic Periodontitis |
Islamic Azad University, Sanandaj |
2013-07 | PHASE2; PHASE3 |
| NCT01368341 | COMPLETED | Erythema Migrans; Erythema Chronicum Migrans; Borreliosis; Lyme Disease; Early Lyme Disease |
Morten Lindbaek |
2011-06 | PHASE4 |
| NCT01727973 | COMPLETED | Graves Ophthalmopathy; Graves Disease; Eye Diseases; Thyroid Diseases; Endocrine System Diseases; Eye Diseases, Hereditary; Hyperthyroidism; Autoimmune Diseases; Immune System Diseases |
Sun Yat-sen University |
2012-10 | PHASE1; PHASE2 |
| NCT01207739 | COMPLETED | Lyme Disease; Borrelia Infection |
Radboud University Medical Center |
2010-09 | PHASE4 |
| NCT01547325 | WITHDRAWN | Dehisced Surgical Wounds |
NanoSHIFT LLC |
2012-05 | |
| NCT01783860 | COMPLETED | Posterior Blepharitis |
Tehran University of Medical Sciences |
2013-01 | PHASE2 |
| NCT01499225 | COMPLETED | Chronic Periodontitis |
Yuhan Corporation |
2011-12 | PHASE2 |
| NCT01474590 | COMPLETED | Acne |
Galderma R&D |
2011-11 | PHASE3 |
| NCT01426269 | COMPLETED | Rosacea |
Galderma R&D |
2011-09 | PHASE4 |
| NCT01243437 | COMPLETED | Plague |
Centers for Disease Control and Prevention |
2010-12 | PHASE2 |
| NCT01418742 | TERMINATED | Colorectal Carcinoma |
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH |
2011-08 | PHASE2 |
| NCT01198509 | COMPLETED | Rheumatoid Arthritis; Psoriatic Arthritis; Periodontal Disease |
NYU Langone Health |
2010-01 | |
| NCT02257658 | COMPLETED | Syphilis |
Los Angeles LGBT Center |
2011-09 | |
| NCT01398072 | UNKNOWN | Chronic Obstructive Pulmonary Disease (COPD). |
University College, London |
2011-12 | PHASE3 |
| NCT00989742 | COMPLETED | Lymphangioleiomyomatosis; Tuberous Sclerosis |
University of Nottingham |
2009-07 | PHASE4 |
| NCT01188954 | WITHDRAWN | Seroma |
Northwell Health |
2010-01 | |
| NCT01112059 | COMPLETED | Cystic Fibrosis |
University of Alabama at Birmingham |
2008-11 | |
| NCT01308619 | COMPLETED | Rosacea |
Galderma R&D |
2011-04 | PHASE4 |
| NCT00917553 | COMPLETED | Diabetic Retinopathy |
Thomas Gardner |
2009-07 | PHASE2 |
| NCT00511875 | COMPLETED | Diabetic Retinopathy |
Thomas Gardner |
2008-07 | PHASE2 |
| NCT01469585 | COMPLETED | Breakthrough Bleeding |
University of Hawaii |
2011-11 | |
| NCT01595594 | COMPLETED | Periodontal Disease; Type 2 Diabetes |
University of Sao Paulo |
2010-03 | PHASE3 |
| NCT01320033 | COMPLETED | Acne Vulgaris |
Galderma R&D |
2011-03-29 | PHASE2 |
| NCT01010295 | COMPLETED | Non-Hodgkin Lymphoma |
International Extranodal Lymphoma Study Group (IELSG) |
2006-09 | PHASE2 |
| NCT00358462 | COMPLETED | Urethritis |
University of Washington |
2007-01 | PHASE3 |
| NCT00353158 | COMPLETED | Healthy Volunteers; Fungal Infections; Bacterial Infections |
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) |
2007-05-25 | PHASE1 |
| NCT01301586 | UNKNOWN | ACNE VULGARIS |
Nexgen Dermatologics, Inc. |
2010-11 | PHASE1; PHASE2 |
| NCT02005653 | COMPLETED | Filarial; Infestation |
Indian Council of Medical Research |
2009-02 | PHASE4 |
| NCT02220751 | COMPLETED | Periodontitis; Type 2 Diabetes Mellitus |
University of Sao Paulo |
2009-03 | PHASE3 |
| NCT00469261 | COMPLETED | Myocardial Infarction; Left Ventricular Remodeling |
Careggi Hospital |
2007-05 | PHASE2 |
| NCT01012726 | TERMINATED | Crohn's Disease |
Gerhard Rogler |
2009-11 | |
| NCT01087476 | UNKNOWN | Mucositis |
Metropolitan Autonomous University |
2010-05 | PHASE2 |
| NCT01375491 | COMPLETED | Type 2 Diabetes; Obesity |
University of California, San Diego |
2009-10 | PHASE4 |
| NCT01245946 | COMPLETED | Acne |
Pontificia Universidad Catolica de Chile |
2010-10 | PHASE2 |
| NCT01014260 | WITHDRAWN | Cardiovascular Disease |
Johns Hopkins University |
2010-09 | PHASE4 |
| NCT01030666 | TERMINATED | Periodontitis |
Peter Eickholz |
2007-04 | PHASE4 |
| NCT00783523 | COMPLETED | Arteriovenous Malformations; Cavernous Angiomas; Brain Aneurysms |
University of California, San Francisco |
2008-03 | PHASE1 |
| NCT00803452 | COMPLETED | Blepharitis |
University of Louisville |
2008-07 | PHASE4 |
| NCT01323101 | COMPLETED | Cystic Fibrosis |
University of Southern California |
2008-04 | PHASE4 |
| NCT00910715 | COMPLETED | Erythema Chronicum Migrans |
University Medical Centre Ljubljana |
2009-06 | |
| NCT00942006 | UNKNOWN | Suspected Early Lyme Neuroborreliosis |
University Medical Centre Ljubljana |
2009-07 | |
| NCT00952861 | WITHDRAWN | Pulmonary Disease, Chronic Obstructive |
Odense University Hospital |
2009-10 | PHASE4 |
| NCT01254799 | COMPLETED | Uterine Hemorrhage |
Omar Mamdouh Shaaban |
2008-01 | PHASE3 |
| NCT00531934 | COMPLETED | Non-Small Cell Lung Cancer |
Hoffmann-La Roche |
2007-10 | PHASE2 |
| NCT00764361 | COMPLETED | Diabetic Foot Ulcer |
NanoSHIFT LLC |
2009-01 | PHASE2 |
| NCT00439166 | COMPLETED | Alzheimer's Disease |
Hamilton Health Sciences Corporation |
2007-02 | PHASE3 |
| NCT02168374 | COMPLETED | Dental Caries |
Aline R F de Castilho |
2008-03 | PHASE2 |
| NCT00480532 | COMPLETED | Contraceptives, Oral |
Oregon Health and Science University |
2007-05 | |
| NCT01798225 | COMPLETED | Periodontal Disease; Type 2 Diabetes Mellitus |
Medical University of South Carolina |
2007-12 | PHASE4 |
| NCT00803842 | WITHDRAWN | Non Small Cell Lung Cancer |
Northwestern University |
2008-10 | |
| NCT00568711 | COMPLETED | Scrub Typhus |
Dong-Min Kim |
2006-09 | |
| NCT00639873 | COMPLETED | Malaria |
Medical University of Vienna |
2008-06 | |
| NCT00892281 | COMPLETED | Rosacea |
Galderma R&D |
2009-04 | PHASE4 |
| NCT00964834 | TERMINATED | Anthrax |
PharmAthene, Inc. |
2009-07 | PHASE1 |
| NCT00246324 | COMPLETED | Multiple Sclerosis |
Louisiana State University Health Sciences Center Shreveport |
2003-12 | PHASE4 |
| NCT00857038 | UNKNOWN | Chronic Obstructive Pulmonary Disease; Inflammation; Pulmonary Emphysema |
Medical Center Alkmaar |
2009-04 | PHASE4 |
| NCT00715858 | UNKNOWN | Alzheimer's Disease |
McMaster University |
2008-05 | PHASE3 |
| NCT00066066 | COMPLETED | Periodontitis; Periodontal Diseases |
The Forsyth Institute |
2003-07 | PHASE2 |
| NCT00560703 | COMPLETED | Blepharitis; Meibomianitis; Dry Eye |
Galderma R&D |
2007-11 | PHASE2 |
| NCT00322465 | COMPLETED | Urethritis |
National Institute of Allergy and Infectious Diseases (NIAID) |
2006-11-17 | PHASE2 |
| NCT00855595 | COMPLETED | Papulopustular Rosacea |
LEO Pharma |
2009-02 | PHASE4 |
| NCT00688064 | COMPLETED | Severe Acne Vulgaris |
Galderma R&D |
2008-08 | PHASE3 |
| NCT00355602 | COMPLETED | Colitis, Ulcerative |
University of Dundee |
2006-07 | |
| NCT00939562 | COMPLETED | Bacterial Infection |
Pfizer |
2008-11 | PHASE4 |
| NCT00830401 | TERMINATED | Minor Intra-uterine Abnormalities |
UMC Utrecht |
2007-06 | PHASE2 |
| NCT00612573 | COMPLETED | Acne Vulgaris |
Warner Chilcott |
2008-02 | PHASE2 |
| NCT00243893 | COMPLETED | Aneurysms; Arteriovenous Malformations |
University of California, San Francisco |
2004-07 | PHASE1 |
| NCT00635609 | COMPLETED | Acne Vulgaris |
Warner Chilcott |
2008-03 | PHASE4 |
| NCT00351273 | COMPLETED | Arthritis, Reactive; Reiter Disease |
University of South Florida |
2006-05 | PHASE3 |
| NCT00170222 | COMPLETED | Chronic Obstructive Pulmonary Disease |
Medical Center Alkmaar |
2002-07 | PHASE4 |
| NCT00837213 | COMPLETED | Acne |
Stiefel, a GSK Company |
2007-08 | PHASE4 |
| NCT00246740 | COMPLETED | Coronary Artery Bypass Grafting; Cardiopulmonary Bypass; Reperfusion Injury |
University of Alberta |
2005-10 | PHASE2 |
| NCT00547170 | COMPLETED | Endometritis |
University of Pittsburgh |
2007-01 | PHASE4 |
| NCT00138801 | COMPLETED | Lyme Neuroborreliosis |
Sorlandet Hospital HF |
2004-03 | PHASE3 |
| NCT01205464 | COMPLETED | Fatigue; Radicular Pain; Cognitive Dysfunction; Paresthesia; Paresis |
Linkoeping University |
2005-02 | |
| NCT00419848 | UNKNOWN | Acne |
Shahid Beheshti University of Medical Sciences |
2006-08 | PHASE2 |
| NCT00495313 | COMPLETED | Rosacea |
CollaGenex Pharmaceuticals |
2007-03 | PHASE4 |
| NCT00376493 | TERMINATED | Septic Abortion |
Hospital de Clinicas de Porto Alegre |
2006-05 | PHASE4 |
| NCT00883818 | COMPLETED | Overactive Bladder |
Samsung Medical Center |
2007-01 | PHASE4 |
| NCT01518192 | COMPLETED | Erythema Migrans; Post-Lyme Disease Symptoms |
University Medical Centre Ljubljana |
2006-06 | PHASE4 |
| NCT00353743 | TERMINATED | Abortion, Septic |
Hospital de Clinicas de Porto Alegre |
2006-05 | |
| NCT00340691 | COMPLETED | Mansonella Perstans Infection; Mp Microfilaremia |
National Institute of Allergy and Infectious Diseases (NIAID) |
2004-12-06 | PHASE2 |
| NCT03584919 | COMPLETED | Erythema Chronicum Migrans |
University Medical Centre Ljubljana |
2006-06-01 | |
| NCT00031499 | COMPLETED | Syphilis |
National Institute of Allergy and Infectious Diseases (NIAID) |
2000-06 | PHASE3 |
| NCT00829764 | COMPLETED | Healthy |
Teva Pharmaceuticals USA |
2006-10 | PHASE1 |
| NCT00829790 | COMPLETED | Healthy |
Teva Pharmaceuticals USA |
2006-10 | PHASE1 |
| NCT00177333 | COMPLETED | Abortion, Induced; Vomiting |
University of Pittsburgh |
2005-09 | PHASE4 |
| NCT00647959 | COMPLETED | Healthy |
Mylan Pharmaceuticals Inc |
2006-03 | PHASE1 |
| NCT00351182 | COMPLETED | Scrub Typhus |
Dong-Min Kim |
2005-09 | PHASE3 |
| NCT00066027 | COMPLETED | Periodontitis |
University of Nebraska |
2002-06-01 | PHASE3 |
| NCT00648180 | COMPLETED | Healthy |
Mylan Pharmaceuticals Inc |
2005-07 | PHASE1 |
| NCT00649571 | COMPLETED | Healthy |
Mylan Pharmaceuticals Inc |
2005-07 | PHASE1 |
| NCT00775918 | COMPLETED | Healthy |
Ranbaxy Laboratories Limited |
2005-06 | |
| NCT00775177 | COMPLETED | Healthy |
Ranbaxy Laboratories Limited |
2005-06 | |
| NCT00016835 | COMPLETED | Periodontal Disease; Diabetes Mellitus, Type 2 |
University of Michigan |
2001-10-17 | PHASE2 |
| NCT00652795 | COMPLETED | To Determine Bioequivalence Under Fasting Conditions |
Par Pharmaceutical, Inc. |
2004-07 | PHASE1 |
| NCT00002872 | COMPLETED | Metastatic Cancer |
Eastern Cooperative Oncology Group |
1997-01-10 | PHASE3 |
| NCT00001101 | COMPLETED | Lyme Disease |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT01380483 | COMPLETED | To Determine Bioequivalence Under Fasting Conditions |
Par Pharmaceutical, Inc. |
2000-01 | PHASE1 |
| NCT01380496 | COMPLETED | To Determine Bioequivalence Under Fed Conditions |
Par Pharmaceutical, Inc. |
1999-11 | PHASE1 |
| NCT00653380 | COMPLETED | To Determine Bioequivalence Under Fasting Conditions |
Par Pharmaceutical, Inc. |
1999-09 | PHASE1 |
| NCT00652704 | COMPLETED | To Determine Bioequivalence Under Fed Conditions |
Par Pharmaceutical, Inc. |
1999-07 | PHASE1 |
| NCT00439400 | COMPLETED | Dry Eye |
Alacrity Biosciences, Inc. |
2007-02 | PHASE2 |
| NCT00484250 | COMPLETED | Oral Lichen Planus |
Mashhad University of Medical Sciences |
2005-09 | PHASE2 |
| NCT00207584 | COMPLETED | Mycoplasma Pneumoniae |
Centers for Disease Control and Prevention |
1994-01 | |
| NCT00631501 | UNKNOWN | Lateral Epicondylalgia (Tennis Elbow) |
Kaunas University of Medicine |
||
| NCT00237016 | COMPLETED | Relapsing Fever, Tick-borne; Jarisch Herxheimer Reaction |
Medical Corps, Israel Defense Force |
2002-04 | PHASE2; PHASE3 |
| NCT00000938 | COMPLETED | Lyme Disease |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00064766 | UNKNOWN | Endometrial Bleeding; Periodontal Disease |
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
2003-02 | PHASE4 |
| NCT00428818 | COMPLETED | Infection |
University of Texas Southwestern Medical Center |
2005-08 | |
| NCT00538967 | COMPLETED | Aortic Aneurysm, Abdominal |
Leiden University Medical Center |
2002-05 | PHASE2 |
| NCT00355459 | WITHDRAWN | Dry Eye Syndrome |
University of Texas Southwestern Medical Center |
2005-08 | |
| NCT00007735 | COMPLETED | Persian Gulf Syndrome; Mycoplasma Infections |
US Department of Veterans Affairs |
1999-01 | PHASE3 |
| NCT00388778 | UNKNOWN | Acne; Inflammation |
Shahid Beheshti University of Medical Sciences |
2005-10 | PHASE2; PHASE3 |
| NCT00126204 | COMPLETED | Aortic Aneurysm |
The Foundation for Barnes-Jewish Hospital |
2004-03 | |
| NCT00041977 | COMPLETED | Acne Rosacea |
CollaGenex Pharmaceuticals |
2002-06 | PHASE3 |
| NCT00000403 | COMPLETED | Osteoarthritis |
Indiana University |
1996-09 | PHASE3 |
| NCT00126399 | COMPLETED | Rosacea |
CollaGenex Pharmaceuticals |
2004-06 | PHASE3 |
| NCT00012688 | COMPLETED | Diabetes Mellitus; Poor Glycemic Control; Peridontal Disease |
US Department of Veterans Affairs |
(data from https://clinicaltrials.gov, updated on 2026-03-20)
Compliance for Clinical Use
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).