CAS No. 15307-81-0
Batch:
Purity:99.70
Chemical Structure
Check the
Diclofenac Potassium
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 15307-81-0 | |
|---|---|---|
| Molecular Formula |
C14H10Cl2KNO2 |
|
| Molecular Weight (MW) | 334.24 | |
| SMILES | C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[K+] |
Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) that acts as a potent cyclooxygenase (COX) inhibitor targeting both COX-1 and COX-2 isoforms. By inhibiting COX activity, it blocks the conversion of arachidonic acid into pro-inflammatory prostaglandins and thromboxanes. This suppression of prostaglandin synthesis leads to reduced inflammation, pain, and fever in various preclinical models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
69 mg/mL
(206.43 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 69 mg/mL |
| Ethanol | Insoluble |
| DMSO |
69 mg/mL
(206.43 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 10 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Diclofenac Potassium Clinical Trials
- Diclofenac Potassium Solubility in DMSO
- Diclofenac Potassium Stock Solution
- Diclofenac Potassium Storage
- Diclofenac Potassium Stability
- Diclofenac Potassium Molecular Weight
- Diclofenac Potassium SMILES
- Diclofenac Potassium Chemical Structure (2D and 3D)
- Diclofenac Potassium SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.