SMILES:

CN1CCN(CC1)C2=CC=C(NC3=NC(=C(C=N3)C(=O)NC4=C(Cl)C=CC=C4C)NC5=CC=CC=C5NC(=O)C=C)C=C2
DGY-06-116 Chemical Structure
Chemical Structure
Check the DGY-06-116 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-(2-chloro-6-methylphenyl)-2-[4-(4-methylpiperazin-1-yl)anilino]-4-[2-(prop-2-enoylamino)anilino]pyrimidine-5-carboxamide
CAS Number 2556836-50-9
Molecular Formula

C32H33ClN8O2
Molecular Weight (MW) 597.11
SMILES CN1CCN(CC1)C2=CC=C(NC3=NC(=C(C=N3)C(=O)NC4=C(Cl)C=CC=C4C)NC5=CC=CC=C5NC(=O)C=C)C=C2
InChIKey HLRQYOGLZWIOPA-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (167.47 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.