Clinical Trials

Numerous clinical trials have evaluated dexamethasone across Early Phase 1 to Phase 4 development for oncologic, hematologic, surgical, and inflammatory indications. Key investigated conditions range from hematologic malignancies—such as relapsed or refractory multiple myeloma, acute lymphoblastic leukemia, and NK-cell lymphomas—to chemotherapy-induced nausea and perioperative management for spinal stenosis and fracture surgeries. Sponsored primarily by academic medical centers, university hospitals, and independent global investigators, these studies comprise active, recruiting, and completed protocols.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07764497 RECRUITING
Colorectal Adenocarcinoma Metastatic in the Liver; Liver Metastasis Colon Cancer; Liver Metastases From Colorectal Cancer; Liver Metastases of Colorectal Cancer
Sunnybrook Health Sciences Centre
 2014-07 PHASE2
NCT07570173 RECRUITING
B-cell Acute Lymphoblastic Leukemia
Merck Sharp & Dohme LLC
 2026-05-18 PHASE2; PHASE3
NCT07624513 NOT_YET_RECRUITING
Multiple Myeloma
Dana-Farber Cancer Institute
 2026-06-08 PHASE3
NCT07748689 NOT_YET_RECRUITING
Relapsed / Refractory Multiple Myeloma
Polish Myeloma Consortium
 2026-10 PHASE2
NCT07728188 NOT_YET_RECRUITING
Relapsed or Refractory Multiple Myeloma
AbbVie
 2026-11-30 PHASE3
NCT04507412 RECRUITING
Arthroplasty, Replacement, Shoulder
Christian Candrian
 2020-09-09 PHASE4
NCT07785609 NOT_YET_RECRUITING
Advanced Solid Tumors; Malignant Neoplasm
Merck Sharp & Dohme LLC
 2026-09-30 PHASE2
NCT05561387 RECRUITING
Plasma Cell Myeloma
SWOG Cancer Research Network
 2023-10-12 PHASE3
NCT05469893 RECRUITING
High-risk Smoldering Multiple Myeloma; Smoldering Multiple Myeloma; Multiple Myeloma
Irene Ghobrial, MD
 2022-08-10 PHASE2
NCT04910503 RECRUITING
Diabetic Macular Edema
Centre Hospitalier Universitaire Dijon
 2021-10-29 PHASE4
NCT07614022 NOT_YET_RECRUITING
Philadelphia Positive Acute Lymphoblastic Leukemia
Wake Forest University Health Sciences
 2026-10 PHASE1
NCT06190158 ACTIVE_NOT_RECRUITING
Type 2 Diabetes; Chronic Kidney Diseases
Brigham and Women's Hospital
 2024-05-15 EARLY_PHASE1
NCT07014462 ENROLLING_BY_INVITATION
AML - Acute Myeloid Leukemia
University of Vermont
 2025-09-01 PHASE1
NCT04729114 RECRUITING
Prostate Cancer; Metastatic Castration Resistant Prostate Cancer; Metastatic Castration-sensitive Prostate Cancer
Astellas Pharma Global Development, Inc.
 2021-06-14 PHASE1
NCT06824467 RECRUITING
Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer
Merck Sharp & Dohme LLC
 2025-04-09 PHASE3
NCT06918431 RECRUITING
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; Lymphoblastic Lymphoma
City of Hope Medical Center
 2025-10-10 PHASE2
NCT07614360 NOT_YET_RECRUITING
Multiple Myeloma
GlaxoSmithKline
 2026-08-03 PHASE2
NCT07315373 NOT_YET_RECRUITING
Immune Thrombocytopenia
Peking University People's Hospital
 2025-12-25 PHASE1
NCT06561854 RECRUITING
Multiple Myeloma; Relapse Multiple Myeloma
Assistance Publique - Hôpitaux de Paris
 2024-12-12 PHASE3
NCT07709715 NOT_YET_RECRUITING
Light Chain (AL) Amyloidosis
Nexcella Inc.
 2027-01 PHASE3
NCT07555938 RECRUITING
Multiple Myeloma
Hoffmann-La Roche
 2026-06-23 PHASE3
NCT07185373 RECRUITING
Primary Central Nervous System Lymphoma
Huashan Hospital
 2025-10-01 PHASE2; PHASE3
NCT04381936 RECRUITING
Pneumonia
University of Oxford
 2020-03-19 PHASE3
NCT07665762 NOT_YET_RECRUITING
Pain, Postoperative; Liposomal Bupivacaine; Dexamethasone; Supraclavicular Brachial Plexus Block; High Risk Factors; Distal Radial Fracture
The University of Hong Kong
 2026-06-15 PHASE3
NCT07588698 NOT_YET_RECRUITING
Non-Hodgkin's B-cell Lymphoma; Lymphoma Non-Hodgkin; Diffuse Large B-Cell Lymphoma (DLBCL)
Carrie Ho, MD
 2026-09-15 PHASE2
NCT07455396 RECRUITING
Asthma (Diagnosis)
Johns Hopkins All Children's Hospital
 2026-08-01 PHASE2
NCT06121843 RECRUITING
Multiple Myeloma
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
 2024-02-22 PHASE1
NCT04546399 RECRUITING
Down Syndrome; Recurrent B Acute Lymphoblastic Leukemia
National Cancer Institute (NCI)
 2020-12-17 PHASE2
NCT07391657 RECRUITING
Relapsed Refractory Multiple Myeloma
AstraZeneca
 2026-02-23 PHASE3
NCT07643103 NOT_YET_RECRUITING
Ph- Acute Lymphoblastic Leukemia (Ph-ALL)
Institute of Hematology & Blood Diseases Hospital, China
 2026-06-12 PHASE2
NCT06136650 RECRUITING
Metastatic Castration-resistant Prostate Cancer (mCRPC); Prostatic Neoplasms
Merck Sharp & Dohme LLC
 2023-12-18 PHASE3
NCT07525466 RECRUITING
Extranodal NK T Cell Lymphoma; Hemophagocytic Lymphohistiocytosis (HLH)
Beijing Tongren Hospital
 2026-04-01 PHASE1; PHASE2
NCT04414475 RECRUITING
Multiple Myeloma, Refractory
Karyopharm Therapeutics Inc
 2020-07-01 PHASE2
NCT03719105 RECRUITING
NK-Cell Lymphoma; NK-Cell Leukemia; Peripheral T Cell Lymphoma
New York Medical College
 2019-03-01 EARLY_PHASE1
NCT03583255 ACTIVE_NOT_RECRUITING
Advanced Malignant Solid Neoplasm; Hematopoietic and Lymphoid System Neoplasm; Locally Advanced Malignant Solid Neoplasm; Metastatic Malignant Solid Neoplasm; Recurrent Malignant Solid Neoplasm
M.D. Anderson Cancer Center
 2018-06-29 PHASE2
NCT06980727 NOT_YET_RECRUITING
Renal Colic
University of Monastir
 2026-08-08 PHASE3
NCT06158841 ACTIVE_NOT_RECRUITING
Multiple Myeloma
AbbVie
 2024-05-19 PHASE3
NCT06142396 RECRUITING
Multiple Myeloma; Renal Failure
Augusta University
 2024-11-01 EARLY_PHASE1
NCT07216820 RECRUITING
Shoulder Surgery; Obesity
University of North Carolina, Chapel Hill
 2026-01-21
NCT02659293 ACTIVE_NOT_RECRUITING
Multiple Myeloma
University of Chicago
 2016-04-26 PHASE3
NCT06901817 RECRUITING
Leptomeningeal Metastasis
Shanghai Cancer Hospital, China
 2025-03-01 PHASE2
NCT07018050 RECRUITING
Relapsed or Refractory Multiple Myeloma
Qilu Pharmaceutical Co., Ltd.
 2025-09-12 PHASE2
NCT07699276 RECRUITING
Cancer (Solid Tumors); Vomiting; Cisplatin; Olanzapine
Mahidol University
 2026-02-10 PHASE2
NCT05721027 RECRUITING
Radiculopathy, Lumbosacral Region; Back Pain With Radiation; Low Back Pain
Montefiore Medical Center
 2023-07-05 PHASE4
NCT07793760 NOT_YET_RECRUITING
Preeclampsia; Spinal Anesthesia-Induced Hypotension; Cesarean Section
Assiut University
 2026-10 PHASE4
NCT03914625 ACTIVE_NOT_RECRUITING
B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Down Syndrome
National Cancer Institute (NCI)
 2019-07-03 PHASE3
NCT05736549 RECRUITING
Total Knee Replacement; Knee Arthroplasty
Yale University
 2023-02-07 PHASE2
NCT05665140 RECRUITING
Newly Diagnosed Multiple Myeloma
University Hopsital Schleswig Holstein Campus Lübeck
 2023-02-03 PHASE2; PHASE3
NCT05972135 RECRUITING
Multiple Myeloma
SCRI Development Innovations, LLC
 2023-10-23 PHASE2
NCT05096663 ACTIVE_NOT_RECRUITING
Advanced Lung Non-Small Cell Carcinoma; Recurrent Lung Non-Small Cell Carcinoma; Stage III Lung Cancer AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIB Lung Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8; Stage IVA Lung Cancer AJCC v8; Stage IVB Lung Cancer AJCC v8
SWOG Cancer Research Network
 2022-03-15 PHASE2; PHASE3
NCT07294118 RECRUITING
Subarachnoid Hemorrhage, Aneurysmal; Headache; Opiate Dependence; Opioid Use
The University of Texas Medical Branch, Galveston
 2026-01-02 PHASE2
NCT06348147 WITHDRAWN
Newly Diagnosed Multiple Myeloma; Multiple Myeloma; Autologous Stem Cell Transplantation
UNC Lineberger Comprehensive Cancer Center
 2026-07 PHASE2
NCT04176718 ACTIVE_NOT_RECRUITING
Multiple Myeloma; Refractory Multiple Myeloma; Multiple Myeloma in Relapse; Relapse
Andrew Yee, MD
 2020-05-18 PHASE2
NCT05558319 RECRUITING
Newly Diagnosed Multiple Myeloma
PETHEMA Foundation
 2022-11-10 PHASE3
NCT07073209 RECRUITING
Hip Fractures
Weill Medical College of Cornell University
 2025-07-10
NCT07773220 NOT_YET_RECRUITING
Cesarean Section Complications
Khyber Teaching Hospital
 2026-09-01
NCT04508790 RECRUITING
Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma
City of Hope Medical Center
 2020-11-24 PHASE2
NCT07722091 NOT_YET_RECRUITING
Hoarseness; Post Operative Complicaiton
Fujian Medical University Union Hospital
 2026-07-27
NCT05519085 RECRUITING
Relapsed or Refractory Multiple Myeloma
Celgene
 2022-09-20 PHASE3
NCT07474909 RECRUITING
Hand Injuries and Disorders; Wrist Sprain
Poznan University of Medical Sciences
 2025-12-10
NCT07386600 RECRUITING
Knee Osteoarthritis
Poznan University of Medical Sciences
 2026-01-01
NCT06692010 NOT_YET_RECRUITING
Clavicle Fracture
Assiut University
 2024-12-01 PHASE4
NCT05514990 ACTIVE_NOT_RECRUITING
Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma
University of Southern California
 2022-10-07 PHASE1; PHASE2
NCT04638790 RECRUITING
Hodgkin Lymphoma, Adult
State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
 2020-02-01 PHASE3
NCT07327931 RECRUITING
Hip Osteoarthritis; Hip Pain Chronic
Poznan University of Medical Sciences
 2026-02-13
NCT07716176 RECRUITING
Nausea and Vomiting Caused by Chemotherapy
Second Affiliated Hospital, Zhejiang University, School of Medicine
 2025-12-12 PHASE3
NCT07077850 ACTIVE_NOT_RECRUITING
Post Operative Urinary Retention; Spinal Aneshtesia
Al-Quds University
 2025-08-20
NCT07324499 RECRUITING
Pain; Interscalene Blocks; Dexamethasone; Bupivacaine
Pontificia Universidad Catolica de Chile
 2026-05-19
NCT07000617 RECRUITING
NK/T Cell Lymphoma
Peking University Cancer Hospital & Institute
 2025-03-21 PHASE2
NCT07699315 NOT_YET_RECRUITING
Symptomatic Irreversible Pulpitis
Watim Medical & Dental College
 2026-08 PHASE4
NCT02718833 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Massachusetts General Hospital
 2016-06-21 PHASE2
NCT03989414 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Celgene
 2019-09-30 PHASE1; PHASE2
NCT02877303 RECRUITING
B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma
M.D. Anderson Cancer Center
 2016-11-01 PHASE2
NCT05325593 ACTIVE_NOT_RECRUITING
Primary Immune Thrombocytopenia
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
 2022-12-02 PHASE3
NCT05392946 ACTIVE_NOT_RECRUITING
Plasma Cell Myeloma
Mayo Clinic
 2022-08-11 PHASE1; PHASE2
NCT06210750 WITHDRAWN
T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma
National Cancer Institute (NCI)
 2024-08-09 PHASE2
NCT02203526 ACTIVE_NOT_RECRUITING
Primary Central Nervous System Lymphoma
National Cancer Institute (NCI)
 2014-08-14 PHASE1
NCT07027540 NOT_YET_RECRUITING
Laparoscopic Cholecystectomy
Assiut University
 2025-08-01 PHASE3
NCT06554626 RECRUITING
Precursor B-Cell Lymphoblastic Leukemia
First Affiliated Hospital of Zhejiang University
 2024-08-15 PHASE2
NCT07742826 RECRUITING
Impacted Mandibular Third Molar Extraction; Impacted Lower Third Molar; Impacted Wisdom Tooth
Final International University
 2024-09-03
NCT03618537 ACTIVE_NOT_RECRUITING
AL Amyloidosis
Memorial Sloan Kettering Cancer Center
 2018-08-02 PHASE2
NCT06789029 RECRUITING
Scoliosis Idiopathic Adolescent
Poznan University of Medical Sciences
 2025-02-01 PHASE4
NCT07469332 NOT_YET_RECRUITING
Postoperative Recovery; PONV
Ankara City Hospital Bilkent
 2026-03-30
NCT05732883 RECRUITING
Voice Change; Hypocalcemia
Tseung Kwan O Hospital, Hong Kong
 2024-07-01 PHASE2
NCT05608837 ACTIVE_NOT_RECRUITING
Uveitis Related Cystoid Macular Edema; Cystoid Macular Edema, Postoperative
Quan Dong Nguyen
 2023-05-26 PHASE2
NCT06945263 ENROLLING_BY_INVITATION
Laparoscopic Appendectomy
University of British Columbia
 2025-05-01
NCT07450638 ACTIVE_NOT_RECRUITING
Impacted Mandibular Third Molar; Postoperative Pain; Trismus; Facial Swelling
Al Salam University
 2026-01-04
NCT04743661 ACTIVE_NOT_RECRUITING
Recurrent Medulloblastoma; Recurrent Ependymoma
Pediatric Brain Tumor Consortium
 2022-04-04 PHASE2
NCT07651150 COMPLETED
Delirium - Postoperative; Hip Fracture Surgeries; Steroid
Jinnah Postgraduate Medical Centre
 2026-01-01
NCT07676396 COMPLETED
Symptomatic Irreversible Pulpitis (SIP)
October 6 University
 2025-04-01 PHASE4
NCT06479317 RECRUITING
Immune Thrombocytopenia With Positive ANA Antibodies
Yunfeng Cheng
 2024-04-24
NCT01917877 UNKNOWN
Pulmonary Fibrosis
Qingdao Central Hospital
 2013-08-01 PHASE2
NCT03641456 UNKNOWN
Myeloma; Newly Diagnosed; High Risk
Sun Yat-sen University
 2020-09-25 PHASE2
NCT07755306 COMPLETED
Post Operative Pain, Acute
Ain Shams University
 2024-03-26 PHASE4
NCT07175623 COMPLETED
Neuromuscular Block, Residual; Pain Management; Postoperative Nausea
Konya City Hospital
 2025-09-16
NCT06133712 RECRUITING
Carpal Tunnel; Dexmedetomidine; Ozone; Dexamethasone
Tanta University
 2023-11-01
NCT06232616 ENROLLING_BY_INVITATION
Epiretinal Membrane
Shanghai Eye Disease Prevention and Treatment Center
 2024-03-11
NCT06126354 WITHDRAWN
Insulin Resistance; Prediabetic State; Non-Alcoholic Fatty Liver Disease; Overweight and Obesity
Columbia University
 2024-07-01 PHASE1
NCT06080880 RECRUITING
Nausea With Vomiting Chemotherapy-Induced
Hubei Cancer Hospital
 2023-12-01
NCT06339151 UNKNOWN
Osteo Arthritis Knee; Pain, Postoperative
Thammasat University Hospital
 2022-03-23
NCT07078786 RECRUITING
Cardiotocography; Steroids
Rawalpindi Medical College
 2025-07-13 PHASE4
NCT07086118 COMPLETED
Cataract; Dexamethasone
Alexandria University
 2025-05-01
NCT05522465 UNKNOWN
Immune Thrombocytopenia; Glucocorticoids; Child, Only
Fujian Medical University Union Hospital
 2022-10-11 PHASE4
NCT06575010 UNKNOWN
Rotator Cuff Tears; Postoperative Pain
Rothman Institute Orthopaedics
 2024-08-26 PHASE4
NCT07081256 COMPLETED
Chemotherapy-Induced Nausea and Vomiting
Qilu Pharmaceutical Co., Ltd.
 2025-01-03 PHASE3
NCT03942224 UNKNOWN
Plasma Cell Myeloma
Emory University
 2019-07-03 PHASE2
NCT02416388 RECRUITING
Acute Myeloid Leukemia (AML)
University Hospital, Angers
 2015-01 PHASE2; PHASE3
NCT06233565 COMPLETED
Foot Injuries and Disorders; Ankle Injuries and Disorders
Poznan University of Medical Sciences
 2024-02-09 PHASE4
NCT04537026 COMPLETED
Lumbar Spinal Stenosis
University of Utah
 2021-06-16 PHASE1; PHASE2
NCT06465992 UNKNOWN
Foot Surgery; Ankle Surgery; Post Operative Pain; Popliteal Nerve Block
Rothman Institute Orthopaedics
 2024-06-17 PHASE4
NCT05911321 ACTIVE_NOT_RECRUITING
Multiple Myeloma; Relapse; Refractory; Aging; Co-morbidity
UNC Lineberger Comprehensive Cancer Center
 2023-12-05 PHASE2
NCT06255847 UNKNOWN
Multiple Myeloma in Relapse
Shanxi Bethune Hospital
 2022-06-15 PHASE2
NCT04091126 ACTIVE_NOT_RECRUITING
Multiple Myeloma
GlaxoSmithKline
 2019-12-18 PHASE1
NCT06387823 UNKNOWN
Acute Respiratory Distress Syndrome
Peking Union Medical College Hospital
 2024-04-15
NCT06044480 UNKNOWN
Aneurysm Abdominal; Endovascular Aneurysm Repair; Postimplantation Syndrome; Dexamethasone
Centro Hospitalar de Lisboa Central
 2023-11-01 PHASE4
NCT04504825 ACTIVE_NOT_RECRUITING
AL Amyloidosis
Alexion Pharmaceuticals, Inc.
 2020-08-25 PHASE3
NCT02237820 UNKNOWN
Heart Failure; Chronic Obstructive Pulmonary Disease
Rabin Medical Center
 2014-11 PHASE4
NCT04287855 UNKNOWN
Multiple Myeloma in Relapse; Multiple Myeloma, Refractory
Poitiers University Hospital
 2020-08-28 PHASE2
NCT06233604 UNKNOWN
Hip Osteoarthritis; Hip Arthropathy; Hip Pain Chronic
Poznan University of Medical Sciences
 2024-04-10 PHASE4
NCT05560542 COMPLETED
Morphine Adverse Reaction
Assiut University
 2022-10-01
NCT06432712 UNKNOWN
Pain
Shoaib Rahim
 2025-01-10 EARLY_PHASE1
NCT03598426 COMPLETED
Hypersensitivity Reactions
Loma Linda University
 2018-08-08 PHASE3
NCT07785596 COMPLETED
Post-operative Inflammation Post-operative Pain Post-operative Swelling (Edema)
Kharadar General Hospital
 2025-01-01
NCT02884180 TERMINATED
Pain, Postoperative
Daniel Hägi-Pedersen
 2017-05-31 PHASE4
NCT04288765 WITHDRAWN
Multiple Myeloma
Grupo Cooperativo de Hemopatías Malignas
 2020-03-01 PHASE3
NCT06906315 COMPLETED
Endodontic Treatment; Pulp Necrosis; Periapical Lesions; Postoperative Pain
University of Salamanca
 2024-11-04 PHASE4
NCT06713733 RECRUITING
Clinical Efficacy of Submucosal Dexamethasone and Oral Trypsin Chymotrypsin for Reduction of Postoperative Sequelae After Lower Third Molar Surgery
B.P. Koirala Institute of Health Sciences
 2024-09-25
NCT06408974 UNKNOWN
Post Cesarean Analgesia
Assiut University
 2024-12-01 PHASE4
NCT05488847 ACTIVE_NOT_RECRUITING
Shoulder Arthropathy; Shoulder Pain
Henry Ford Health System
 2022-06-25 PHASE4
NCT05536063 UNKNOWN
Pediatric Cardiac Surgery
Assiut University
 2023-05
NCT05720949 COMPLETED
ACL; Anterior Cruciate Ligament Injuries
Hospital for Special Surgery, New York
 2023-01-12 PHASE4
NCT06006624 UNKNOWN
ACL; Postoperative Pain
Rothman Institute Orthopaedics
 2023-08-21 PHASE4
NCT06074263 TERMINATED
Pain Management
Rutgers, The State University of New Jersey
 2023-11-27 PHASE4
NCT05367271 COMPLETED
Plantar Fasciitis
Western Institute for Veterans Research
 2022-08-23 PHASE2; PHASE3
NCT03107182 COMPLETED
HPV-Related Squamous Cell Carcinoma; HNSCC
University of Chicago
 2017-06-27 PHASE2
NCT04423367 COMPLETED
Acquired Pure Red Cell Aplasia
Institute of Hematology & Blood Diseases Hospital, China
 2020-09-13 PHASE2
NCT03530683 TERMINATED
Lymphoma; Multiple Myeloma; Acute Myeloid Leukemia; Diffuse Large B-Cell Lymphoma
Pfizer
 2018-05-14 PHASE1
NCT05578885 UNKNOWN
Regional Anesthesia
Michael Bishay Shehata Keroles
 2024-02-01
NCT06351644 Not yet recruiting
Relapsed and/or Refractory Multiple Myeloma
Adriana Rossi|Icahn School of Medicine at Mount Sinai
 2024-06-03 Phase 1|Phase 2
NCT04050644 UNKNOWN
Age-related Cataract
Universitaire Ziekenhuizen KU Leuven
 2018-10-30 PHASE4
NCT02697383 COMPLETED
Multiple Myeloma; High Risk Smoldering Multiple Myeloma
Memorial Sloan Kettering Cancer Center
 2016-02 PHASE1
NCT06367855 Not yet recruiting
Spinal Stenosis Lumbar|Disc Degeneration|Disc Disease|Fusion of Spine|Surgery
Potsawat Surabotsopon|Thammasat University Hospital
 2024-05-01 Phase 4
NCT06266481 UNKNOWN
Postoperative Sore Throat
Pharos University in Alexandria
 2024-03-01 PHASE2; PHASE3
NCT05945797 COMPLETED
Common Bile Duct Diseases; Common Bile Duct Calculi; Common Bile Duct Stricture; Common Bile Duct Neoplasms; Common Bile Duct Dilatation
Gujranwala medical college District Headquarters Hospital, Gujranwala
 2023-08-01
NCT06137924 UNKNOWN
Pain, Postoperative; Nausea, Postoperative; Vomiting, Postoperative; Analgesia; Opioid Use
Universidad Simón Bolívar
 2023-12-02 PHASE3
NCT06367725 Recruiting
Acute Lymphoblastic Leukemia
University of Aarhus
 2024-04-11 --
NCT06186921 UNKNOWN
Pulpitis
Jamia Millia Islamia
 2023-12-02
NCT05755880 UNKNOWN
Anesthesia
Assiut University
 2023-03
NCT05904275 UNKNOWN
Post Operative Pain
National Trauma Center
 2023-08-01
NCT06759584 COMPLETED
Temporomandibular Disorder
Minia University
 2023-04-28
NCT00390793 COMPLETED
Acute Lymphoblastic Leukemia; BCR-ABL1 Fusion Protein Expression; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Philadelphia Chromosome Positive; Recurrent Acute Lymphoblastic Leukemia; t(9;22)
M.D. Anderson Cancer Center
 2006-09-28 PHASE2
NCT04484623 ACTIVE_NOT_RECRUITING
Multiple Myeloma
GlaxoSmithKline
 2020-10-01 PHASE3
NCT03269136 COMPLETED
Multiple Myeloma
Pfizer
 2017-11-29 PHASE1
NCT06527976 COMPLETED
Postoperative Pain
Assiut University
 2022-02-15
NCT05979597 COMPLETED
Regional Anesthesia
Samsun Education and Research Hospital
 2023-08-10
NCT05687981 UNKNOWN
Hernia, Inguinal
Tanta University
 2023-01 EARLY_PHASE1
NCT04965155 ACTIVE_NOT_RECRUITING
Relapsed Multiple Myeloma
EMN Trial Office S.r.l. Impresa Sociale
 2021-03-21 PHASE2
NCT03289299 ACTIVE_NOT_RECRUITING
Smoldering Multiple Myeloma
International Myeloma Foundation
 2018-05-25 PHASE2
NCT04895592 COMPLETED
Metastatic Malignant Neoplasm in the Brain; Metastatic Malignant Solid Neoplasm
Emory University
 2021-07-20 EARLY_PHASE1
NCT04323280 TERMINATED
Pericarditis Acute
Rabin Medical Center
 2020-02-14 PHASE4
NCT04890626 COMPLETED
SARS-CoV-2 Infection
Instituto de Investigación Hospital Universitario La Paz
 2020-04-04 PHASE3
NCT04113018 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Wake Forest University Health Sciences
 2020-01-10 PHASE2
NCT04551833 UNKNOWN
Regional Anesthesia
Assiut University
 2021-04-01 PHASE4
NCT04524455 COMPLETED
Acute Lymphoblastic Leukemia
Amgen
 2020-10-02 PHASE1
NCT04540133 COMPLETED
Oral Lichen Planus; Mucous Membrane Pemphigoid; Pemphigus Vulgaris; Chronic Graft-versus-host-disease
University of California, San Francisco
 2020-12-26 PHASE2
NCT06085417 COMPLETED
Bupivacaine; Dexamethasone; Magnesıum Sulphate; Adjuvant
Yuzuncu Yil University
 2023-01-02
NCT03830749 COMPLETED
Immune Thrombocytopenia
Humanity & Health Medical Group Limited
 2018-07-01 PHASE2
NCT03773107 COMPLETED
Multiple Myeloma
Wake Forest University Health Sciences
 2019-01-03 PHASE1; PHASE2
NCT04258683 WITHDRAWN
Multiple Myeloma
Canadian Myeloma Research Group
 2021-02-17 PHASE2
NCT03871829 TERMINATED
Multiple Myeloma
Janssen Research & Development, LLC
 2019-05-31 PHASE2
NCT03247413 TERMINATED
Neuritis; Radiofrequency Ablation
Johns Hopkins University
 2019-09-01 PHASE4
NCT04536662 UNKNOWN
Congenital Adrenal Hyperplasia
Shanghai Jiao Tong University School of Medicine
 2020-10-01 PHASE4
NCT05286008 UNKNOWN
Postoperative Nausea and Vomiting; Postoperative Pain
Tianjin Medical University General Hospital
 2022-03-18
NCT05415826 UNKNOWN
Diabetic Retinopathy
Peking University People's Hospital
 2022-06-15
NCT03589326 ACTIVE_NOT_RECRUITING
Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)
Takeda
 2018-10-04 PHASE3
NCT04565301 COMPLETED
Pain, Postoperative
Cairo University
 2021-06-20
NCT05470530 COMPLETED
Healthy
Ain Shams University
 2022-03-10 PHASE1
NCT02215980 COMPLETED
Multiple Myeloma
Fondazione EMN Italy Onlus
 2014-07 PHASE3
NCT04461028 WITHDRAWN
Rotator Cuff Tears
University of Pennsylvania
 2019-02-21 PHASE3
NCT03215524 COMPLETED
Multiple Myeloma
Canadian Myeloma Research Group
 2017-10-25 PHASE2
NCT03554473 COMPLETED
Carcinoma, Small Cell; Lung Cancer; Small Cell Lung Cancer
National Cancer Institute (NCI)
 2018-09-11 PHASE1; PHASE2
NCT04838379 COMPLETED
Cholecystitis; Appendicitis
Assiut University
 2021-04-01
NCT02844322 COMPLETED
Waldenström Macroglobulinemia
Institute of Hematology & Blood Diseases Hospital, China
 2016-05 PHASE4
NCT05170789 WITHDRAWN
Relapsed Multiple Myeloma; Refractory Multiple Myeloma
Tulane University School of Medicine
 2022-04-27 PHASE2
NCT02461888 COMPLETED
Multiple Myeloma
University of Leeds
 2015-12 PHASE2
NCT03121534 TERMINATED
Hematopoietic/Lymphoid Cancer; Richter's Transformation
M.D. Anderson Cancer Center
 2017-06-22 PHASE2
NCT04765371 COMPLETED
Coronavirus Infection
Hôpital NOVO
 2021-03-03 PHASE3
NCT04976777 COMPLETED
Macular Edema
AbbVie
 2021-10-12 PHASE3
NCT04762745 UNKNOWN
Relapsed, Refractory, Multiple Myeloma
Sun Yat-sen University
 2021-02 PHASE1; PHASE2
NCT02513186 COMPLETED
Plasma Cell Myeloma
Sanofi
 2015-09-30 PHASE1
NCT04791475 COMPLETED
Brachial Plexus Block; Dexmedetomidine; Dexamethasone; Bupivacaine
Tribhuvan University Teaching Hospital, Institute Of Medicine.
 2021-02-22
NCT04902638 UNKNOWN
Diabetes; Knee Osteoarthritis
The University of Hong Kong
 2020-07-01
NCT04237012 COMPLETED
Dry Eye Syndromes
The Eye Centers of Racine and Kenosha
 2019-12-16 PHASE4
NCT04911361 COMPLETED
Dry Eye
Research Insight LLC
 2021-08-10 PHASE4
NCT03606980 TERMINATED
Apophysitis; Juvenile
Children's Health System, Inc.
 2018-11-05 PHASE2
NCT03639610 TERMINATED
Renal Impairment; Multiple Myeloma
Oncopeptides AB
 2018-08-28 PHASE2
NCT01554852 UNKNOWN
Multiple Myeloma
University of Leeds
 2010-05 PHASE3
NCT03578081 COMPLETED
Malignant Neoplasm
Alliance for Clinical Trials in Oncology
 2018-11-20 PHASE3
NCT04265534 TERMINATED
Non-Small Cell Lung Cancer; Non-squamous Non-small-cell Lung Cancer; Non-Squamous Non-Small Cell Neoplasm of Lung; KEAP1 Gene Mutation; NRF2 Gene Mutation; NFE2L2 Gene Mutation
Calithera Biosciences, Inc
 2020-07-24 PHASE2
NCT03527576 COMPLETED
Postoperative Pain; Lower Limb Injury
Eric Albrecht
 2018-05-01 PHASE4
NCT03314636 ACTIVE_NOT_RECRUITING
Myeloma
Oslo University Hospital
 2018-03-16 PHASE2
NCT04593706 UNKNOWN
Keloid; Hypertrophic Scar; Scars; Scarring
Tel-Aviv Sourasky Medical Center
 2020-11-01
NCT02577783 UNKNOWN
Multiple Myeloma
The First Affiliated Hospital of Soochow University
 2015-10 PHASE4
NCT03657420 WITHDRAWN
Multiple Myeloma
Massachusetts General Hospital
 2019-05-30 PHASE1
NCT04538820 UNKNOWN
Postoperative Nausea and Vomiting
Diskapi Yildirim Beyazit Education and Research Hospital
 2021-03-01 PHASE4
NCT04708821 COMPLETED
Bilateral Conjunctivitis (Disorder)
Clinical Research Center of Florida
 2021-04-30 PHASE4
NCT02918747 UNKNOWN
Lymphoma
Hunan Cancer Hospital
 2016-09 PHASE2
NCT01091831 COMPLETED
Multiple Myeloma
Fondazione EMN Italy Onlus
 2009-07 PHASE3
NCT05361291 COMPLETED
Pulpitis - Irreversible
Jamia Millia Islamia
 2020-02-01
NCT04917250 UNKNOWN
Extranodal NK/T-cell Lymphoma
Beijing Tongren Hospital
 2020-03-20 PHASE2
NCT05195242 COMPLETED
COVID-19; Thrombosis Embolism; Bleeding
Karolinska Institutet
 2020-08-27 PHASE3
NCT03564704 UNKNOWN
Leukemia; Leukemia, Acute; Adult Lymphoblastic Lymphoma; Leukemia, Lymphoblastic; Leukemia, T Cell; Adult Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma; Lymphoblastic Leukemia
Nanfang Hospital, Southern Medical University
 2016-02-14 PHASE2; PHASE3
NCT03416374 COMPLETED
Relapsed and/or Refractory Multiple Myeloma
Takeda
 2018-02-18 PHASE4
NCT03960151 WITHDRAWN
Germ Cell Tumor
Costantine Albany
 2018-05 PHASE2
NCT04781751 UNKNOWN
Pain, Neuropathic
Minia University
 2021-02-28
NCT02755597 COMPLETED
Relapsed/Refractory Multiple Myeloma
AbbVie
 2016-07-11 PHASE3
NCT04047446 COMPLETED
Shoulder Pain
Hospital for Special Surgery, New York
 2019-07-11 PHASE4
NCT04527770 COMPLETED
Pain Syndrome
Minia University
 2020-09-01
NCT02556424 COMPLETED
Inflammatory Macular Edema
Nantes University Hospital
 2016-01 PHASE3
NCT03256045 TERMINATED
Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma
University of Washington
 2018-02-08 PHASE2
NCT03520985 TERMINATED
Refractory Multiple Myeloma
Swiss Cancer Institute
 2018-10-01 PHASE2
NCT00391170 COMPLETED
Graft vs Host Disease
National Heart, Lung, and Blood Institute (NHLBI)
 2006-11-24 PHASE2
NCT03763760 COMPLETED
Postoperative Pain; Postoperative Nausea and Vomiting; Hip Osteoarthritis; Perioperative/Postoperative Complications; Surgery; Opioid Use; Catastrophizing Pain; Chronic Pain
Copenhagen University Hospital, Hvidovre
 2019-01-29 PHASE4
NCT02278315 COMPLETED
Multiple Myeloma
Cellectar Biosciences, Inc.
 2015-02 PHASE1
NCT03891355 UNKNOWN
Mantle Cell Lymphoma
Fondazione Italiana Linfomi - ETS
 2019-09-30 PHASE2
NCT01208766 COMPLETED
Multiple Myeloma
Stichting Hemato-Oncologie voor Volwassenen Nederland
 2011-01 PHASE3
NCT02339740 ACTIVE_NOT_RECRUITING
Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2); PML-RARA
Children's Oncology Group
 2015-07-21 PHASE3
NCT04711213 COMPLETED
Cataract in Inflammatory Ocular Disorders
iDrop, Inc.
 2020-09-14 PHASE2
NCT03487133 COMPLETED
Relapsed and/or Refractory Cutaneous T-cell Lymphoma
Samsung Medical Center
 2017-09-19 PHASE2
NCT03876041 COMPLETED
Systemic Inflammatory Response Syndrome
Assiut University
 2019-09-01 PHASE4
NCT02541383 COMPLETED
Multiple Myeloma
Intergroupe Francophone du Myelome
 2015-09 PHASE3
NCT04347980 TERMINATED
Respiratory Distress Syndrome, Adult; COVID-19
Centre Chirurgical Marie Lannelongue
 2020-04-17 PHASE3
NCT01054144 COMPLETED
Multiple Myeloma
H. Lee Moffitt Cancer Center and Research Institute
 2010-01-14 PHASE2
NCT03876938 UNKNOWN
Antiemetic for Highly Emetogenic Chemotherapy
Mahidol University
 2019-03-01 PHASE3
NCT01670097 COMPLETED
Advanced Cancers; Hematologic Disorder; Solid Tumors
M.D. Anderson Cancer Center
 2013-01 PHASE2
NCT04519385 COMPLETED
Pneumonia, Viral
South Valley University
 2020-03-01
NCT04790292 COMPLETED
Anesthesia
Ain Shams University
 2020-01-01 PHASE4
NCT03109691 UNKNOWN
Bilateral Superficial Cervical Block
Assiut University
 2018-01-28
NCT03701321 WITHDRAWN
Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma
National Cancer Institute (NCI)
 2019-01-25 PHASE1; PHASE2
NCT03382821 COMPLETED
Cervical Radiculopathy
University of Utah
 2017-09-15 PHASE4
NCT01363128 COMPLETED
Acute Lymphoblastic Leukemia; Adult Acute Lymphoblastic Leukemia in Complete Remission; Burkitt Leukemia; Burkitt Lymphoma; CD20 Positive; Childhood Acute Lymphoblastic Leukemia in Complete Remission; Lymphoblastic Lymphoma
M.D. Anderson Cancer Center
 2011-07-12 PHASE2
NCT03110562 COMPLETED
Multiple Myeloma
Karyopharm Therapeutics Inc
 2017-05-24 PHASE3
NCT04619303 COMPLETED
Diabetic Macular Edema; Diabetic Retinopathy
Lions Eye Institute, Perth, Western Australia
 2017-02-07 PHASE4
NCT03201965 COMPLETED
Amyloidosis
Janssen Research & Development, LLC
 2017-10-05 PHASE3
NCT01543490 COMPLETED
Active, Symptomatic Blepharitis
Sun Pharmaceutical Industries Limited
 2018-03-30 PHASE3
NCT01090089 COMPLETED
Multiple Myeloma
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH
 2010-03-01 PHASE3
NCT03822182 COMPLETED
Rotator Cuff Tear; Pain, Postoperative
Indiana University
 2018-10-24 PHASE4
NCT03177317 COMPLETED
Colonic Neoplasms
Seoul National University Bundang Hospital
 2017-05-01
NCT04690647 COMPLETED
Anesthesia, Local; Analgesia; Arthropathy of Hip
Saint Lucas Hospital, Poland
 2018-09-28
NCT01850524 COMPLETED
Multiple Myeloma
Millennium Pharmaceuticals, Inc.
 2013-04-29 PHASE3
NCT03193788 UNKNOWN
Bladder Cancer; Ureter Cancer; Transitional Cell Carcinoma
Asan Medical Center
 2017-01 PHASE3
NCT02858804 COMPLETED
Mantle Cell Lymphoma
Institute of Hematology & Blood Diseases Hospital, China
 2016-01 PHASE4
NCT03192150 COMPLETED
Inflammation and Pain Associated With Cataract Surgery
Sun Pharmaceutical Industries Limited
 2018-01-03 PHASE3
NCT03506360 COMPLETED
Recurrent Plasma Cell Myeloma
Mayo Clinic
 2018-06-19 PHASE2
NCT02605356 WITHDRAWN
Multiple Myeloma
Bayer
 2016-10 PHASE1; PHASE2
NCT02654990 COMPLETED
Multiple Myeloma
pharmaand GmbH
 2016-04-27 PHASE2
NCT03234972 COMPLETED
Multiple Myeloma
Janssen Research & Development, LLC
 2017-11-30 PHASE3
NCT02917941 COMPLETED
Relapsed and/or Refractory Multiple Myeloma
Takeda
 2016-11-01 PHASE2
NCT02336815 COMPLETED
Multiple Myeloma
Karyopharm Therapeutics Inc
 2015-05-26 PHASE2
NCT02393859 COMPLETED
Leukemia, Acute Lymphoblastic
Amgen
 2015-11-10 PHASE3
NCT03158688 COMPLETED
Relapsed Multiple Myeloma; Refractory Multiple Myeloma
Amgen
 2017-06-13 PHASE3
NCT03789227 COMPLETED
Pain, Chronic
Mansoura University
 2018-07-01
NCT02793011 COMPLETED
Pediatric Post-tonsillectomy Pain
Nationwide Children's Hospital
 2016-06 PHASE4
NCT03950674 COMPLETED
Non-Small-Cell Lung Carcinoma
Merck Sharp & Dohme LLC
 2016-02-22 PHASE3
NCT03610893 COMPLETED
Pain, Postoperative; Pain, Acute; Upper Extremity Injury
University of Chile
 2018-08-16
NCT01999335 TERMINATED
Multiple Myeloma
Amgen
 2014-07-30 PHASE1
NCT03192137 COMPLETED
Inflammation and Pain Associated With Cataract Surgery
Sun Pharmaceutical Industries Limited
 2018-01-30 PHASE3
NCT03079453 COMPLETED
Edema
Bezmialem Vakif University
 2018-07-15 PHASE4
NCT02410694 COMPLETED
Multiple Myeloma
Arbeitsgemeinschaft medikamentoese Tumortherapie
 2015-04 PHASE2
NCT02928029 TERMINATED
Multiple Myeloma
Bayer
 2017-02-10 PHASE1; PHASE2
NCT03057015 UNKNOWN
Postoperative Pain
University of Vermont
 2017-05-22 PHASE4
NCT03668860 COMPLETED
Preterm Birth; Antenatal Corticosteroids
Children's Hospital Medical Center, Cincinnati
 2018-09-20 PHASE1
NCT03436225 UNKNOWN
Bronchiolitis; Respiratory Syncytial Virus
Assiut University
 2019-02 PHASE1
NCT03398044 COMPLETED
Nasal Obstruction; Nasopharyngeal Obstruction; Snoring; Apnea, Obstructive; Hearing Loss; Otitis
University Hospital Ostrava
 2017-01-01
NCT01084252 COMPLETED
Hematological Malignancy
Sanofi
 2010-05-11 PHASE1; PHASE2
NCT03334487 WITHDRAWN
Small Cell Lung Cancer
AbbVie
 2018-03-15 PHASE3
NCT03740659 COMPLETED
Cataract
NTC srl
 2018-09-04 PHASE2
NCT02945527 TERMINATED
Neurocysticercosis
Universidad Peruana Cayetano Heredia
 2015-12-04 PHASE2; PHASE3
NCT03366584 UNKNOWN
Hyaline Membrane Disease; Necrotizing Enterocolitis of Newborn
Indonesia University
 2017-01 PHASE4
NCT03555929 COMPLETED
Hand Wound; Wrist Wound; Forearm Wound; Hand Fracture; Wrist Fracture; Forearm Fracture
Assistance Publique - Hôpitaux de Paris
 2018-04-04 PHASE3
NCT00707083 COMPLETED
Leukemia
Prince of Wales Hospital, Shatin, Hong Kong
 2008-05-01 PHASE3
NCT02520115 COMPLETED
Adnexal Mass; Borderline Ovarian Epithelial Tumor; Ovarian Clear Cell Tumor; Ovarian Endometrioid Tumor; Ovarian Neoplasm; Ovarian Serous Tumor; Recurrent Ovarian Carcinoma
Barbara Ann Karmanos Cancer Institute
 2015-08 PHASE1
NCT02114502 WITHDRAWN
Myeloma
M.D. Anderson Cancer Center
 2014-09 PHASE2
NCT02834260 COMPLETED
Keratoconus; Fuchs' Endothelial Dystrophy; Congenital Hereditary Stromal Dystrophy of the Cornea
Centre Hospitalier Universitaire de Saint Etienne
 2017-01-10 PHASE2
NCT02672527 COMPLETED
Soft Tissue Sarcoma
Gustave Roussy, Cancer Campus, Grand Paris
 2015-01-22 PHASE3
NCT02579863 TERMINATED
Multiple Myeloma
Merck Sharp & Dohme LLC
 2015-10-19 PHASE3
NCT02548962 TERMINATED
Multiple Myeloma
Pharmacyclics LLC.
 2016-03 PHASE1; PHASE2
NCT02825186 UNKNOWN
Ophthalmology
Tel-Aviv Sourasky Medical Center
 2016-07
NCT03094663 COMPLETED
Knee Arthropathy
Hospital for Special Surgery, New York
 2017-02-28 PHASE4
NCT02189343 COMPLETED
Multiple Myeloma
Celgene
 2014-09-15 PHASE1
NCT02407600 UNKNOWN
Non-small Cell Lung Cancer; Vomiting; Nausea; Emesis
Ajeet Gajra
 2015-04 PHASE2
NCT02389543 WITHDRAWN
Multiple Myeloma
Karyopharm Therapeutics Inc
 2015-07 PHASE1; PHASE2
NCT01270932 COMPLETED
Renal Failure; Multiple Myeloma
University Health Network, Toronto
 2010-11 PHASE2
NCT02111785 TERMINATED
Chronic Subdural Hematoma
University of Virginia
 2014-03 PHASE2; PHASE3
NCT02195479 COMPLETED
Multiple Myeloma
Janssen Research & Development, LLC
 2014-12-09 PHASE3
NCT02725008 COMPLETED
Asthma
Geoffrey W Jara-Almonte
 2015-11 PHASE3
NCT01926665 COMPLETED
Lymphoma
M.D. Anderson Cancer Center
 2014-06-17 PHASE1
NCT02914054 COMPLETED
ITP; Croticosteroid Therapy
Isfahan University of Medical Sciences
 2016-10-01 PHASE2; PHASE3
NCT02970643 UNKNOWN
Chemotherapy-induced Nausea and Vomiting
Hee Jun Kim
 2016-07
NCT02424045 COMPLETED
T-cell Lymphoma
Samsung Medical Center
 2015-05 PHASE2
NCT02289222 TERMINATED
Multiple Myeloma
Ashraf Badros
 2014-12-30 PHASE1; PHASE2
NCT01913990 UNKNOWN
Emesis
Ottawa Hospital Research Institute
 2011-09 PHASE4
NCT01692197 COMPLETED
Leukemia
M.D. Anderson Cancer Center
 2013-02-01 PHASE2
NCT02372240 TERMINATED
Multiple Myeloma
Vivolux AB
 2015-04-08 PHASE1; PHASE2
NCT02402543 COMPLETED
Hemorrhoids; Fissure in Ano; Rectal Fistula; Anal Condyloma
University of Vermont
 2014-06
NCT01316770 TERMINATED
Sjögren's Syndrome; Xerostomia
National Institute of Dental and Craniofacial Research (NIDCR)
 2011-05-01 PHASE2
NCT02309385 COMPLETED
Non-Infectious Anterior Uveitis
Aciont Inc
 2014-10 PHASE1; PHASE2
NCT02834286 UNKNOWN
Immune Thrombocytopenia
Hospital Universitario Dr. Jose E. Gonzalez
 2015-03 PHASE2
NCT03117140 COMPLETED
Anesthesia, Local
Melinda Seering
 2013-12 PHASE4
NCT02965196 UNKNOWN
Low Back Pain
Hillel Yaffe Medical Center
 2016-12
NCT02818985 COMPLETED
Postoperative Pain
Assiut University
 2016-06 PHASE2
NCT02585531 UNKNOWN
Bronchiolitis
Hospital General Naval de Alta Especialidad - Escuela Medico Naval
 2015-11 PHASE2
NCT01787669 COMPLETED
Diabetes; Diabetic Macular Oedema; Diabetic Macular Edema; Diabetic Retinopathy
University of Sydney
 2013-06 PHASE2
NCT02578121 WITHDRAWN
Multiple Myeloma
University of Arkansas
 2015-12 PHASE2
NCT03007927 COMPLETED
Pain, Postoperative
SEBASTIAN ROCHE
 2016-08 PHASE4
NCT02525718 COMPLETED
Breast Cancer
Northwestern University
 2015-08 PHASE2
NCT02348528 COMPLETED
Multiple Myeloma
Celgene
 2012-09-11 PHASE2
NCT01522872 UNKNOWN
Multiple Myeloma
Threshold Pharmaceuticals
 2012-02 PHASE1; PHASE2
NCT02550795 COMPLETED
Postoperative Nausea and Vomiting
Gachon University Gil Medical Center
 2015-09
NCT01846390 COMPLETED
Peripheral T-Cell Lymphoma; Diffuse Large B-Cell Lymphoma
Canadian Cancer Trials Group
 2013-10-01 PHASE1
NCT01748942 COMPLETED
Dysphagia; Pain; Stage I Oropharyngeal Squamous Cell Carcinoma; Stage II Oropharyngeal Squamous Cell Carcinoma; Stage III Oropharyngeal Squamous Cell Carcinoma
OHSU Knight Cancer Institute
 2012-12
NCT02768168 COMPLETED
Adverse Effect
General Hospital of Ningxia Medical University
 2016-05
NCT02485249 TERMINATED
Macular Edema
Eyegate Pharmaceuticals, Inc.
 2015-07 PHASE1; PHASE2
NCT01861340 COMPLETED
Myeloma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
 2014-05 EARLY_PHASE1
NCT00381680 COMPLETED
B-cell Childhood Acute Lymphoblastic Leukemia; L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia
Children's Oncology Group
 2007-03 PHASE3
NCT01980589 COMPLETED
Multiple Myeloma
Amgen
 2013-08 PHASE1
NCT01442428 WITHDRAWN
Immune Reconstitution Inflammatory Syndrome; Immune Reconstitution Syndrome; Tuberculosis; HIV-infection/Aids
University of Minnesota
 2014-01 PHASE2; PHASE3
NCT01495624 TERMINATED
Duration of Interscalene Block
The Cleveland Clinic
 2011-12
NCT01450215 COMPLETED
Multiple Myeloma
Karolinska University Hospital
 2011-03 PHASE2
NCT01410201 TERMINATED
Epiretinal Membrane; Macular Edema
Barnes Retina Institute
 2011-08
NCT01397552 TERMINATED
Lumbar Spine Disc Herniation; Lumbar Radiculitis; Lumbar Back Pain
State University of New York - Upstate Medical University
 2009-09
NCT01501149 UNKNOWN
Nasal and Nasal-type NK/T-cell Lymphoma
Mingzhi Zhang
 2011-01 PHASE4
NCT02346110 COMPLETED
Arthrosis, Unspecified, Ankle and Foot
University of Aarhus
 2015-04 PHASE4
NCT02305173 COMPLETED
Respiratory; Disorder, Functional, Impaired
Instituto Mexicano del Seguro Social
 2014-11 PHASE3
NCT02193698 COMPLETED
POEMS Syndrome
Chiba University
 2014-07 PHASE2
NCT02415335 COMPLETED
Suspected Appendicitis
Nordsjaellands Hospital
 2015-04 PHASE2
NCT01485835 COMPLETED
Multiple Myeloma
Emory University
 2012-01 PHASE1
NCT01078974 TERMINATED
Waldenstrom's Macroglobulinemia
Steven P. Treon, MD, PhD
 2010-05 PHASE1
NCT02216071 COMPLETED
Acute Otitis Externa
Exela Pharma Sciences, LLC.
 2014-07-20 PHASE3
NCT01971658 COMPLETED
Multiple Myeloma
Nantes University Hospital
 2013-10 PHASE3
NCT02036983 COMPLETED
Bilateral Inguinal Hernia Repair
Indiana University
 2013-11
NCT01023308 COMPLETED
Multiple Myeloma
Novartis Pharmaceuticals
 2009-12-21 PHASE3
NCT01477762 COMPLETED
Post Traumatic Stress Disorder
Emory University
 2011-11
NCT02145715 UNKNOWN
Multiple Myeloma
Prof Jamie Cavenagh
 2013-01 PHASE1; PHASE2
NCT01801774 UNKNOWN
Inflammation; Intraocular Pressure
Mahidol University
 2012-05 PHASE4
NCT02204241 COMPLETED
Multiple Myeloma
European Myeloma Network B.V.
 2014-06 PHASE1; PHASE2
NCT01581151 UNKNOWN
Retinal Vein Occlusion
Brian Burke, MPH
 2011-09
NCT02206503 COMPLETED
Multiple Myeloma
Fondazione EMN Italy Onlus
 2013-03 PHASE2
NCT02056717 COMPLETED
Uterine Myoma; Adenomyosis
Severance Hospital
 2014-04
NCT02026050 COMPLETED
Postoperative Pain
TC Erciyes University
 2014-01 PHASE4
NCT01641419 WITHDRAWN
Pain, Sciatic Block
Baylor College of Medicine
 2012-07
NCT01976195 WITHDRAWN
Immune Thrombocytopenia
Shandong University
 2013-10 PHASE2
NCT01892163 COMPLETED
Diabetic Macular Edema
Moorfields Eye Hospital NHS Foundation Trust
 2013-03 PHASE3
NCT01238159 COMPLETED
Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-Type
Samsung Medical Center
 2010-08 PHASE2
NCT01660867 WITHDRAWN
Acute Bronchiolitis
Seoul National University Hospital
 2012-08 PHASE4
NCT01568866 COMPLETED
Multiple Myeloma
Amgen
 2012-06-20 PHASE3
NCT02344732 COMPLETED
Corneal Diseases
Universiti Sains Malaysia
 2013-10
NCT01331590 COMPLETED
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Washington University School of Medicine
 2011-07 EARLY_PHASE1
NCT01239797 COMPLETED
Lymphoma; Multiple Myeloma
Bristol-Myers Squibb
 2011-06-20 PHASE3
NCT01521533 COMPLETED
Multiple Myeloma
TME Pharma AG
 2012-03 PHASE2
NCT02011113 COMPLETED
Multiple Myeloma
Celgene Corporation
 2013-12 PHASE2
NCT00081939 COMPLETED
Multiple Myeloma
University of Arkansas
 2004-01 PHASE2
NCT02062905 COMPLETED
Chronic Allergic Conjunctivitis
Ocular Therapeutix, Inc.
 2014-03 PHASE2
NCT01698281 TERMINATED
Breast Cancer
AEterna Zentaris
 2012-12 PHASE2
NCT01488279 COMPLETED
Pre-diabetes; Impaired Fasting Glucose; Impaired Glucose Tolerance
University of Vermont
 2012-09
NCT01602224 COMPLETED
Multiple Myeloma
Eli Lilly and Company
 2012-07 PHASE2
NCT00866307 COMPLETED
Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia
Children's Oncology Group
 2009-02-23 PHASE1
NCT01484626 TERMINATED
Multiple Myeloma
Loyola University
 2011-05-05 PHASE1; PHASE2
NCT00953420 COMPLETED
Nasopharyngeal Carcinoma
Baylor College of Medicine
 2009-11 PHASE2
NCT01275664 TERMINATED
Nausea and Vomiting; Ovarian Brenner Tumor; Ovarian Clear Cell Cystadenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Cystadenocarcinoma; Ovarian Seromucinous Carcinoma; Ovarian Serous Cystadenocarcinoma; Stage II Ovarian Cancer; Stage IIA Fallopian Tube Cancer; Stage IIA Ovarian Cancer; Stage IIB Fallopian Tube Cancer; Stage IIB Ovarian Cancer; Stage IIC Fallopian Tube Cancer; Stage IIC Ovarian Cancer; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Cancer; Stage IIIA Primary Peritoneal Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Cancer; Stage IIIB Primary Peritoneal Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Cancer; Stage IIIC Primary Peritoneal Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Primary Peritoneal Cancer; Undifferentiated Ovarian Carcinoma
Gynecologic Oncology Group
 2011-06
NCT01896427 UNKNOWN
Oral Health; Molar, Third
Mohammad Javad Shirani
 2013-04 PHASE4
NCT01045876 WITHDRAWN
Adrenal Insufficiency
St. Paul's Hospital, Canada
 2010-05 PHASE4
NCT00317408 UNKNOWN
Lymphoma
European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma
 2004-04
NCT01537861 TERMINATED
Multiple Myeloma
Washington University School of Medicine
 2012-06 EARLY_PHASE1
NCT01876290 COMPLETED
Postoperative Nausea and Vomiting
Hopital Foch
 2013-05 PHASE4
NCT00103285 COMPLETED
Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia
Children's Oncology Group
 2005-04-11 PHASE3
NCT01405924 TERMINATED
Nausea; Vomiting
Merck Sharp & Dohme LLC
 2011-10-25 PHASE2
NCT02581046 COMPLETED
Cataract
Sun Yat-sen University
 2011-01
NCT01698801 COMPLETED
Multiple Myeloma
Celgene
 2012-10-01 PHASE2
NCT01857115 COMPLETED
Multiple Myeloma
European Myeloma Network B.V.
 2013-04 PHASE1; PHASE2
NCT01734057 WITHDRAWN
Purpura; Idiopathic Thrombocytopenic Purpura
Shandong University
 2012-07 PHASE3
NCT02467010 COMPLETED
Multiple Myeloma
University Medical Center Groningen
 2008-09 PHASE2
NCT00972959 COMPLETED
Multiple Myeloma
University of Athens
 2009-07 PHASE2
NCT01309451 COMPLETED
Diabetic Macular Edema
Maturi, Raj K., M.D., P.C.
 2011-03 PHASE4
NCT00617591 COMPLETED
Multiple Myeloma
H. Lee Moffitt Cancer Center and Research Institute
 2008-01 PHASE2
NCT00923273 TERMINATED
Carcinoma, Non-Small-Cell Lung
National Cancer Institute (NCI)
 2008-02-29 PHASE1; PHASE2
NCT00507416 COMPLETED
Multiple Myeloma
Millennium Pharmaceuticals, Inc.
 2007-06 PHASE3
NCT01005914 TERMINATED
Leukemia
OHSU Knight Cancer Institute
 2009-06 PHASE2
NCT01616173 COMPLETED
Fracture of Ankle
Northwestern University
 2012-06 PHASE4
NCT01431014 COMPLETED
Swelling
Chang Gung Memorial Hospital
 2011-08 PHASE4
NCT01078454 COMPLETED
Light Chain Deposition Disease; Primary Systemic Amyloidosis
National Cancer Institute (NCI)
 2010-11 PHASE3
NCT01346787 COMPLETED
Multiple Myeloma
European Myeloma Network B.V.
 2011-07 PHASE2
NCT00642954 COMPLETED
Relapsed or Refractory Multiple Myeloma
Merck Sharp & Dohme LLC
 2008-02-13 PHASE1
NCT00869973 TERMINATED
Emesis
S. Maria Hospital, Terni
 2009-09 PHASE3
NCT01392079 COMPLETED
Chronic Lymphocytic Leukemia
University of Ulm
 2008-02 PHASE2
NCT01698749 COMPLETED
Diabetic Macular Edema; Macular Edema, Cystoid; Vision Disorders; Clinically Significant Macular Edema
Post Graduate Institute of Medical Education and Research, Chandigarh
 2011-12
NCT01698788 COMPLETED
Diabetic Macular Edema; Vision Disorders
Post Graduate Institute of Medical Education and Research, Chandigarh
 2011-05
NCT00584168 COMPLETED
Pain
University of Oklahoma
 2005-03 PHASE1
NCT01029054 COMPLETED
Multiple Myeloma
University of Michigan Rogel Cancer Center
 2009-09 PHASE1; PHASE2
NCT00426101 COMPLETED
Hemophagocytic Lymphohistiocytosis
Karolinska University Hospital
 2004-01 PHASE3
NCT01311167 TERMINATED
Liver Cirrhosis
Insel Gruppe AG, University Hospital Bern
 2011-02 PHASE3
NCT01012336 COMPLETED
Chemotherapy-Induced Nausea and Vomiting; Ovarian Cancer
Samsung Medical Center
 2010-05 PHASE2
NCT02353468 TERMINATED
Refractory Plasma Cell Myeloma
University of Colorado, Denver
 2009-12 PHASE2
NCT01297010 COMPLETED
Vomiting Postoperative
Instituto Materno Infantil Prof. Fernando Figueira
 2011-03 PHASE3
NCT00656656 COMPLETED
Pemphigus
University of Luebeck
 2008-01 PHASE2
NCT00562965 TERMINATED
Lymphoma, Follicular
Pfizer
 2007-11 PHASE3
NCT00290823 COMPLETED
Neurocysticercosis
National Institute of Allergy and Infectious Diseases (NIAID)
 2006-04 PHASE3
NCT01227863 UNKNOWN
Bacterial Conjunctivitis; Acute
Azidus Brasil
 2011-02 PHASE3
NCT01030601 COMPLETED
Diabetes; Macular Edema; Pseudophakia
University Health Network, Toronto
 2010-01 PHASE2
NCT00907452 COMPLETED
Myeloma
Intergroupe Francophone du Myelome
 2009-07-29
NCT00801138 TERMINATED
Anesthesia, Local; Shoulder Surgery
The Cleveland Clinic
 2008-11
NCT00334672 UNKNOWN
Nonneoplastic Condition
Children's Cancer and Leukaemia Group
 2006-03 PHASE3
NCT01024075 UNKNOWN
Chronic Rhinosinusitis
University of Calgary
 2009-11 PHASE4
NCT00801580 UNKNOWN
Lymphoid Leukemia
University of Bologna
 2008-03 PHASE2
NCT00482261 COMPLETED
Multiple Myeloma
Peter MacCallum Cancer Centre, Australia
 2007-06 PHASE2
NCT00742404 UNKNOWN
Multiple Myeloma and Plasma Cell Neoplasm
Oncotherapeutics
 2008-07 PHASE2
NCT01007500 COMPLETED
Nausea; Vomiting
Yonsei University
 2009-09 PHASE4
NCT00524589 TERMINATED
Prostate Cancer
Roswell Park Cancer Institute
 2006-04 PHASE2
NCT01107951 COMPLETED
Immune Thrombocytopenic Purpura
Hospital Universitario Dr. Jose E. Gonzalez
 2010-04 PHASE2
NCT01001091 COMPLETED
Allergic Conjunctivitis
Alcon Research
 2009-12 PHASE2
NCT00871910 COMPLETED
Solid Tumors; Lymphoma, Non-Hodgkin; Multiple Myeloma
Merck Sharp & Dohme LLC
 2006-10-11 PHASE1
NCT00525447 COMPLETED
Multiple Myeloma
Seagen Inc.
 2007-08 PHASE1
NCT00799227 COMPLETED
Diabetic Macular Edema; Vitrectomy
Allergan
 2009-01-01 PHASE2
NCT00956462 UNKNOWN
Glaucoma
University Health Network, Toronto
 2007-07
NCT00663169 COMPLETED
Arthritis, Gouty
Novartis
 2008-04 PHASE2
NCT00833560 COMPLETED
Multiple Myeloma
Janssen-Cilag G.m.b.H
 2006-03 PHASE2
NCT00601172 COMPLETED
Nausea and Vomiting, Chemotherapy-Induced
GlaxoSmithKline
 2008-03-10 PHASE3
NCT00609817 TERMINATED
Multiple Myeloma
La Jolla Pharmaceutical Company
 2008-05 PHASE1
NCT00992355 COMPLETED
Cataract
Veroia General Hospital
 2009-01
NCT00314743 COMPLETED
Nausea; Vomiting
Washington University School of Medicine
 2005-10 EARLY_PHASE1
NCT00733382 UNKNOWN
Migraine Headache
Shiraz University of Medical Sciences
 2008-02 PHASE1
NCT00343460 COMPLETED
Nausea and Vomiting; Unspecified Adult Solid Tumor, Protocol Specific
Heron Therapeutics
 2006-06 PHASE3
NCT00573391 TERMINATED
Multiple Myeloma
University of Arkansas
 2006-08 PHASE3
NCT00136084 COMPLETED
Leukemia, Myelocytic, Acute
St. Jude Children's Research Hospital
 2002-08 PHASE3
NCT00305812 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
NCIC Clinical Trials Group
 2006-03-09 PHASE2
NCT00609765 TERMINATED
Pancreatic Cancer
H. Lee Moffitt Cancer Center and Research Institute
 2007-08 PHASE2
NCT00457678 WITHDRAWN
Age Related Macular Degeneration
Vitreous -Retina- Macula Consultants of New York
 2007-01 PHASE2
NCT00272285 COMPLETED
Vomiting; Nausea
Astellas Pharma Inc
 2006-01 PHASE3
NCT00308594 TERMINATED
Cervical Radiculopathy
University of Manitoba
 2006-11 PHASE2
NCT00041132 COMPLETED
Lymphoma
SWOG Cancer Research Network
 2002-09 PHASE2
NCT01341262 COMPLETED
Multiple Myeloma
IRCCS Azienda Ospedaliero-Universitaria di Bologna
 2002-03 PHASE2
NCT00499551 WITHDRAWN
Uveitis
Asociación para Evitar la Ceguera en México
 2007-09 PHASE1; PHASE2
NCT00561743 COMPLETED
Multiple Myeloma
Janssen-Ortho Inc., Canada
 2005-11 PHASE2
NCT00250926 COMPLETED
Waldenstrom's Macroglobulinemia
Dana-Farber Cancer Institute
 2005-10 PHASE2
NCT00176293 TERMINATED
Prostate Cancer
University of Kentucky
 2005-10 PHASE2
NCT00131261 COMPLETED
Multiple Myeloma
Valerio Therapeutics
 2005-01 PHASE2
NCT00592566 TERMINATED
Leptospirosis
Mahidol University
 2003-07 PHASE2; PHASE3
NCT00111748 COMPLETED
Multiple Myeloma
University of Arkansas
 2005-02 PHASE3
NCT00144963 COMPLETED
Acute Lymphoblastic Leukemia
Acrotech Biopharma Inc.
 2002-07 PHASE1; PHASE2
NCT00054158 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
Roswell Park Cancer Institute
 2004-08 PHASE2
NCT00057564 COMPLETED
Multiple Myeloma
Celgene Corporation
 2003-02 PHASE3
NCT00227682 TERMINATED
Multiple Myeloma and Plasma Cell Neoplasm
OHSU Knight Cancer Institute
 2004-06 PHASE2
NCT00008242 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
Memorial Sloan Kettering Cancer Center
 2000-08 PHASE2
NCT00056160 COMPLETED
Multiple Myeloma
Celgene
 2003-01-01 PHASE3
NCT00005596 COMPLETED
Leukemia
Children's Oncology Group
 2000-04 PHASE3
NCT00063726 COMPLETED
Multiple Myeloma
Millennium Pharmaceuticals, Inc.
 2002-04 PHASE3
NCT00532961 COMPLETED
Inflammation
Bausch & Lomb Incorporated
 2005-02 PHASE4
NCT00002700 COMPLETED
Leukemia; Lymphoma
European Organisation for Research and Treatment of Cancer - EORTC
 1995-08 PHASE3
NCT00002548 COMPLETED
Multiple Myeloma
SWOG Cancer Research Network
 1994-01 PHASE3
NCT00005987 TERMINATED
Multiple Myeloma and Plasma Cell Neoplasm
Masonic Cancer Center, University of Minnesota
 2000-08 PHASE2
NCT00199095 COMPLETED
Adult Acute Lymphocytic Leukemia
Goethe University
 1997-02 PHASE4
NCT00002816 COMPLETED
Leukemia
Children's Oncology Group
 1996-12 PHASE3
NCT00199069 COMPLETED
Adult Acute Lymphocytic Leukemia
Goethe University
 1993-04 PHASE4
NCT00005777 TERMINATED
Bronchopulmonary Dysplasia; Respiratory Distress Syndrome; Infant, Newborn; Infant, Low Birth Weight; Infant, Small for Gestational Age; Infant, Premature
NICHD Neonatal Research Network
 1998-02 PHASE3
NCT00011362 COMPLETED
Infant, Newborn; Infant, Low Birth Weight; Infant, Small for Gestational Age; Infant, Premature; Bronchopulmonary Dysplasia
NICHD Neonatal Research Network
 1992-09 PHASE3
NCT00028886 UNKNOWN
Multiple Myeloma and Plasma Cell Neoplasm
Commissie Voor Klinisch Toegepast Onderzoek
 2001-03 PHASE3
NCT00006240 COMPLETED
Leukemia
National Heart, Lung, and Blood Institute (NHLBI)
 2000-10 PHASE2
NCT00226668 WITHDRAWN
Brain Edema; Brain Tumor
Celtic Pharma Development Services
 2006-01 PHASE3
NCT00193869 COMPLETED
Spinal Cord Compression From Neoplasm Metastasis
Trans Tasman Radiation Oncology Group
 2001-09 PHASE2
NCT00006250 UNKNOWN
Lymphoma
Lymphoma Trials Office
 2000-05 PHASE3
NCT00004785 COMPLETED
Bronchopulmonary Dysplasia
National Center for Research Resources (NCRR)
 1995-11 PHASE3
NCT00087815 UNKNOWN
Brain and Central Nervous System Tumors; Cognitive/Functional Effects; Radiation Toxicity
Barrett Cancer Center
 2003-09
NCT00148018 TERMINATED
Hodgkin Disease
University of Cologne
 2005-03 PHASE2
NCT00516009 UNKNOWN
RADICULAR PAIN
Ziv Hospital
 2007-08
NCT00016887 UNKNOWN
Lymphoma
German Low Grade Lymphoma Study Group
 2000-12 PHASE3
NCT00261612 UNKNOWN
Lymphoma, Mantle-Cell
Medical University of Vienna
 2005-01 PHASE2
NCT00169572 COMPLETED
Nausea and Vomiting; Chemotherapy-Induced
GlaxoSmithKline
 2005-02 PHASE2
NCT00017602 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
Genta Incorporated
 2000-12 PHASE3
NCT00102609 COMPLETED
Soft Tissue Sarcoma; Sarcoma; Neoplasms, Connective and Soft Tissue; Neoplasms by Histologic Type; Neoplasms
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
 2005-04 PHASE1

(data from https://clinicaltrials.gov, updated on 2026-08-14)

Check the Dexamethasone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

As a potent synthetic glucocorticoid receptor agonist and interleukin receptor modulator, dexamethasone downregulates pro-inflammatory cytokine transcription while promoting autophagy and apoptotic cell death pathways. This robust immunosuppressive and anti-inflammatory action provides the biological basis for its therapeutic utility in treating hematologic malignancies such as multiple myeloma and acute lymphoblastic leukemia, as well as suppressing hyperinflammatory immune responses.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

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Note: Technical data last updated: Sep 1, 2026.