CAS No. 30197-14-9
Batch:
Purity:99.88
Chemical Structure
Check the
Desoxyrhaponticin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol | |
|---|---|---|
| CAS Number | 30197-14-9 | |
| Molecular Formula |
C21H24O8 |
|
| Molecular Weight (MW) | 404.41 | |
| SMILES | COC1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)O)OC3OC(CO)C(O)C(O)C3O | |
| InChIKey | MFMQRDLLSRLUJY-DXKBKAGUSA-N |
Desoxyrhaponticin is a natural stilbene glycoside that acts as a fatty acid synthase (FAS/FASN) inhibitor. By targeting FASN activity, it suppresses de novo lipogenesis and disrupts cellular energy homeostasis in malignant cells. This inhibition impairs tumor lipid metabolism, leading to the activation of apoptotic pathways and reduced cell viability across various human cancer lines. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(247.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.