CAS No. 84408-37-7
Batch:
Purity:99.75
Chemical Structure
Check the
Desciclovir
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 84408-37-7 | |
|---|---|---|
| Molecular Formula |
C8H11N5O2 |
|
| Molecular Weight (MW) | 209.21 | |
| SMILES | C1=C2C(=NC(=N1)N)N(C=N2)COCCO |
Desciclovir (BW A515U) is a prodrug of the nucleoside analogue acyclovir with antiviral activity against herpesviruses. It undergoes bioactivation into acyclovir via oxidation catalyzed by xanthine oxidase. The resulting active metabolite is phosphorylated to acyclovir triphosphate, which selectively inhibits viral DNA polymerase, suppressing viral DNA chain elongation and blocking herpes virus replication. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
42 mg/mL
(200.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 25 mg/mL |
| Ethanol | 3 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.