CAS No. 111664-82-5

Batch: Purity:99.94
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Dehydroevodiamine hydrochloride Chemical Structure
Chemical Structure
Check the Dehydroevodiamine hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-1,3,5,7,9,15,17,19-octaen-14-one;hydrochloride
CAS Number 111664-82-5
Molecular Formula

C19H15N3O.HCl
Molecular Weight (MW) 337.8
SMILES CN1C2=CC=CC=C2C(=O)N3C1=C4C(=C5C=CC=CC5=N4)CC3.Cl
InChIKey SVOMSEHNGXLQRU-UHFFFAOYSA-N

Ordering Information

Biological Activity

Dehydroevodiamine hydrochloride is a natural quinolone alkaloid inhibitor of acetylcholinesterase (AChE) isolated from Evodia rutaecarpa. It modulates nitric oxide signaling pathways to induce vasorelaxant and hypotensive responses in vascular tissues. Furthermore, dehydroevodiamine hydrochloride exerts neuroprotective effects by preserving cholinergic neurotransmission and mitigating cellular damage, making it a useful tool for investigating cardiovascular regulation and neurodegenerative pathways.

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 37 mg/mL (109.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.