SMILES:
CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C
Chemical Structure
Check the
Dapivirine (TMC120)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-[[4-(2,4,6-trimethylanilino)pyrimidin-2-yl]amino]benzonitrile | |
|---|---|---|
| CAS Number | 244767-67-7 | |
| Molecular Formula |
C20H19N5 |
|
| Molecular Weight (MW) | 329.4 | |
| SMILES | CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C | |
| InChIKey | ILAYIAGXTHKHNT-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
34 mg/mL
(103.21 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Dapivirine (TMC120) Clinical Trials
- Dapivirine (TMC120) Solubility in DMSO
- Dapivirine (TMC120) Stock Solution
- Dapivirine (TMC120) Storage
- Dapivirine (TMC120) Stability
- Dapivirine (TMC120) Molecular Weight
- Dapivirine (TMC120) CAS Number
- Dapivirine (TMC120) Chemical Structure (2D and 3D)
- Dapivirine (TMC120) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.