CAS No. 10121-91-2

Batch: Purity:98.95
Check CoA
Dansylcadaverine (Monodansyl cadaverine) Chemical Structure
Chemical Structure
Check the Dansylcadaverine (Monodansyl cadaverine) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 10121-91-2
Molecular Formula

C17H25N3O2S
Molecular Weight (MW) 335.46
SMILES CN(C)C1=CC=CC2=C(C=CC=C12)[S](=O)(=O)NCCCCCN

Ordering Information

Biological Activity

Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent lysosomotropic agent and substrate for transglutaminases that is widely used to selectively label autophagic vacuoles in cultured cells. By accumulating within acidic intracellular compartments and interacting with cellular membrane components, dansylcadaverine effectively blocks receptor-mediated endocytosis of extracellular ligands and alters downstream trafficking along endocytic and autophagic pathways. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 67 mg/mL (199.72 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 8 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.