CAS No. 76822-21-4
Batch:
Purity:99.68
Chemical Structure
Check the
Danshensu
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 76822-21-4 | |
|---|---|---|
| Molecular Formula |
C9H10O5 |
|
| Molecular Weight (MW) | 198.17 | |
| SMILES | C1=CC(=C(C=C1CC(C(=O)O)O)O)O |
Biological Activity
Danshensu (Salvianic acid A) is a herbal preparation with potential antitumor and anti-angiogenesis activities that inhibits cytochrome P450 enzymes, including CYP2E1 and CYP2C9. Downstream, Danshensu attenuates vascular endothelial growth factor (VEGF) signaling, suppressing endothelial cell proliferation, migration, and capillary tube formation. These actions disrupt tumor-associated microvascular sprouting, leading to reduced vascularization and inhibition of tumor growth in preclinical models. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 10 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
| Water | 23 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
Jump to
Note: Technical data last updated: Sep 1, 2026.