Cytarabine has been evaluated in numerous clinical trials across developmental stages from Phase I through Phase IV. The drug is predominantly investigated for hematological malignancies, including acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syndromes, and mantle cell lymphoma, with support from academic institutions, cooperative networks, and industry sponsors. Spanning active to completed statuses, research includes a clinical trial assessing cytarabine combined with siltuximab for myeloid leukemia and a clinical trial evaluating intensified regimens in high-risk lymphoblastic leukemia.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07072585 | NOT_YET_RECRUITING | Stage II T Lymphoblastic Leukemia/Lymphoma; Stage III T Lymphoblastic Leukemia/Lymphoma; Stage IV T Lymphoblastic Leukemia/Lymphoma; T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
Children's Oncology Group |
2026-08-28 | PHASE2; PHASE3 |
| NCT07387926 | RECRUITING | Acute Lymphoblastic Leukemia; Leukemia, Lymphoblastic, Acute, Philadelphia-Positive; Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia |
Novartis Pharmaceuticals |
2026-07-05 | PHASE1; PHASE2 |
| NCT03013998 | RECRUITING | Previously Untreated Relapsed Refractory Acute Myeloid Leukemia |
Beat AML, LLC |
2016-11 | PHASE2; PHASE3 |
| NCT07007312 | RECRUITING | Acute Myeloid Leukemia (AML) |
Kura Oncology, Inc. |
2025-09-26 | PHASE3 |
| NCT07227584 | RECRUITING | Acute Lymphoblastic Leukemia; Philadelphia Chromosome-Negative Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia (ALL); Leukemia |
Dana-Farber Cancer Institute |
2026-04-03 | PHASE2 |
| NCT07078591 | RECRUITING | Acute Myeloid Leukemia |
Beijing 302 Hospital |
2025-06-20 | PHASE2 |
| NCT07223814 | RECRUITING | Acute Myeloid Leukemia |
Stichting Hemato-Oncologie voor Volwassenen Nederland |
2026-03-01 | PHASE3 |
| NCT01356290 | RECRUITING | Medulloblastoma Recurrent; Ependymoma Recurrent; ATRT Recurrent; Rare CNS Tumor Recurrent |
Medical University of Vienna |
2014-04 | PHASE2 |
| NCT05735184 | RECRUITING | Acute Myeloid Leukemia; Mixed Lineage Leukemia Gene Mutation; Refractory AML; AML With Mutated NPM1; Acute Myeloid Leukemia Recurrent; Acute Myeloid Leukemia, in Relapse; NPM1 Mutation; KMT2Ar; Myeloid Sarcoma; Nucleophosmin 1-mutated Acute Myeloid Leukemia |
Kura Oncology, Inc. |
2023-07-18 | PHASE1 |
| NCT04953780 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia |
West Virginia University |
2021-09-27 | PHASE1 |
| NCT05245656 | RECRUITING | Mantle Cell Lymphoma |
Kim, Seok Jin |
2022-10-18 | PHASE2 |
| NCT07686107 | NOT_YET_RECRUITING | Leukemia, Myeloid, Acute |
Therapeutic Advances in Childhood Leukemia Consortium |
2026-08-31 | PHASE2 |
| NCT07651176 | ENROLLING_BY_INVITATION | Acute Myeloid Leukemia; Lisaftoclax |
First Affiliated Hospital of Zhejiang University |
2026-03-01 | PHASE2; PHASE3 |
| NCT07761702 | NOT_YET_RECRUITING | AML (Acute Myelogenous Leukemia) |
Shanghai Jiao Tong University School of Medicine |
2026-10-01 | PHASE3 |
| NCT07563179 | RECRUITING | Acute Myeloid Leukemia; Relapse/Recurrence |
Shenzhen University General Hospital |
2026-04-21 | PHASE2 |
| NCT04293562 | RECRUITING | Acute Myeloid Leukemia |
Children's Oncology Group |
2020-07-21 | PHASE3 |
| NCT05658640 | RECRUITING | Acute Lymphoblastic Leukemia, in Relapse; Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent; Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent; Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory; Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory |
Princess Maxima Center for Pediatric Oncology |
2023-11-14 | PHASE1; PHASE2 |
| NCT07507760 | RECRUITING | Acute Myeloid Leukemia With Gene Mutations |
PETHEMA Foundation |
2026-06-12 | PHASE2 |
| NCT06918431 | RECRUITING | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; Lymphoblastic Lymphoma |
City of Hope Medical Center |
2025-10-10 | PHASE2 |
| NCT07423104 | NOT_YET_RECRUITING | Acute Myeloid Leukemia (AML) |
University of Rochester |
2026-08-15 | PHASE2 |
| NCT07259707 | RECRUITING | Acute Myeloid Leukemia; FLT3 Internal Tandem Duplication Positive; Intermediate Risk Acute Myeloid Leukemia; Fit Patients |
First Affiliated Hospital of Zhejiang University |
2026-01-25 | PHASE2 |
| NCT07301138 | NOT_YET_RECRUITING | Acute Lymphoblastic Leukemia |
Ruijin Hospital |
2025-12-15 | PHASE2 |
| NCT05342584 | RECRUITING | Acute Myeloid Leukemia; Myelodysplastic Syndromes |
Montefiore Medical Center |
2022-05-25 | PHASE1 |
| NCT07498465 | WITHDRAWN | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Childhood Acute Lymphoblastic Leukemia; Childhood Acute Myeloid Leukemia; Childhood Mixed Phenotype Acute Leukemia; Mixed Phenotype Acute Leukemia |
Children's Oncology Group |
2026-09-10 | PHASE1 |
| NCT07059975 | RECRUITING | Acute Myeloid Leukemia; Pediatric AML |
Baylor College of Medicine |
2025-10-22 | EARLY_PHASE1 |
| NCT05749276 | RECRUITING | Adult Patients With Adverse Risk Acute Myeloblastic Leukemia |
Nantes University Hospital |
2025-02-06 | PHASE1 |
| NCT05260528 | RECRUITING | Acute Myeloid Leukemia |
Centre Hospitalier Universitaire de Nice |
2023-05-03 | PHASE2 |
| NCT07735117 | NOT_YET_RECRUITING | Acute Myeloid Leukemia (AML); Myelodysplastic Syndromes (MDS) |
Ruijin Hospital |
2026-07-30 | PHASE3 |
| NCT03643276 | RECRUITING | Acute Lymphoblastic Leukemia, Pediatric |
Martin Schrappe |
2018-07-15 | PHASE3 |
| NCT05199051 | ACTIVE_NOT_RECRUITING | AML; Leukaemia (Acute Myeloid) |
Centre Antoine Lacassagne |
2023-06-03 | PHASE2 |
| NCT06905509 | RECRUITING | Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements; Recurrent High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements; Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified; Recurrent Nodal Marginal Zone Lymphoma; Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Refractory High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements; Refractory High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements; Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified; Refractory Nodal Marginal Zone Lymphoma; Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma |
University of California, Davis |
2025-07-31 | PHASE2 |
| NCT04546399 | RECRUITING | Down Syndrome; Recurrent B Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2020-12-17 | PHASE2 |
| NCT07642453 | NOT_YET_RECRUITING | Acute Myeloid Leukemia (AML) |
Hematology department of the 920th hospital |
2026-06-01 | PHASE2 |
| NCT06262438 | RECRUITING | Acute Myeloid Leukemia in Children |
Princess Maxima Center for Pediatric Oncology |
2024-02-06 | PHASE2 |
| NCT07643103 | NOT_YET_RECRUITING | Ph- Acute Lymphoblastic Leukemia (Ph-ALL) |
Institute of Hematology & Blood Diseases Hospital, China |
2026-06-12 | PHASE2 |
| NCT03589729 | RECRUITING | Acute Myeloid Leukemia; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Blasts 10 Percent or More of Bone Marrow Nucleated Cells; High Risk Myelodysplastic Syndrome; Myeloid Sarcoma; Myeloproliferative Neoplasm; Philadelphia Chromosome Positive |
M.D. Anderson Cancer Center |
2018-09-19 | PHASE2 |
| NCT05253495 | RECRUITING | Non-hodgkin Lymphoma; Hodgkin Lymphoma |
New York Medical College |
2022-02-01 | PHASE2 |
| NCT06930352 | RECRUITING | Acute Myeloid Leukemia |
Uma Borate |
2026-10-01 | PHASE2 |
| NCT04797767 | RECRUITING | Acute Biphenotypic Leukemia; Acute Myeloid Leukemia; Mixed Phenotype Acute Leukemia; Myeloid Neoplasm; Relapsed Acute Biphenotypic Leukemia; Relapsed Acute Myeloid Leukemia; Relapsed Mixed Phenotype Acute Leukemia; Relapsed Myeloid Neoplasm; Refractory Acute Biphenotypic Leukemia; Refractory Acute Myeloid Leukemia; Refractory Mixed Phenotype Acute Leukemia; Refractory Myeloid Neoplasm; Recurrent Myeloid Sarcoma |
University of Washington |
2022-02-04 | PHASE1; PHASE2 |
| NCT05365035 | RECRUITING | Myelodysplastic Syndromes; Myeloproliferative Chronic Myelomonocytic Leukemia |
M.D. Anderson Cancer Center |
2022-09-23 | PHASE2 |
| NCT05886049 | RECRUITING | Acute Myeloid Leukemia; Acute Myeloid Leukemia With KMT2A Rearrangement; Acute Myeloid Leukemia With NPM1 Mutation; Secondary Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2024-06-20 | PHASE1 |
| NCT04128748 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia; Blasts More Than 10 Percent of Bone Marrow Nucleated Cells; High Risk Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Myelodysplastic Syndrome; Refractory Acute Myeloid Leukemia; Refractory Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2020-05-27 | PHASE1; PHASE2 |
| NCT07441967 | NOT_YET_RECRUITING | Hematologic Malignancies |
Institute of Hematology & Blood Diseases Hospital, China |
2026-02-20 | PHASE2 |
| NCT06744556 | ACTIVE_NOT_RECRUITING | AML |
Institute of Hematology & Blood Diseases Hospital, China |
2025-01-21 | PHASE2 |
| NCT06744504 | RECRUITING | AML; RUNX1-RUNX1T1 Fusion Protein Expression |
Institute of Hematology & Blood Diseases Hospital, China |
2025-01-10 | PHASE3 |
| NCT07255872 | NOT_YET_RECRUITING | Acute Myeloid Leukemia |
Sichuan Baili Pharmaceutical Co., Ltd. |
2026-03 | PHASE2; PHASE3 |
| NCT06660368 | RECRUITING | Relapsed or Refractory Acute Myeloid Leukemia (AML) |
H. Lee Moffitt Cancer Center and Research Institute |
2024-11-26 | PHASE2 |
| NCT06504459 | RECRUITING | Acute Monocytic Leukemia; Acute Myeloid Leukemia |
OHSU Knight Cancer Institute |
2025-01-03 | PHASE2 |
| NCT06692452 | WITHDRAWN | Lymphoma; Peripheral T Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Enteropathy-Associated T-Cell Lymphoma; Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma |
Eric Jacobsen, MD |
2024-12-24 | PHASE2 |
| NCT03214562 | RECRUITING | High Risk Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2017-09-26 | PHASE1; PHASE2 |
| NCT03914625 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Down Syndrome |
National Cancer Institute (NCI) |
2019-07-03 | PHASE3 |
| NCT07444710 | NOT_YET_RECRUITING | Ann Arbor Stage II Mantle Cell Lymphoma; Ann Arbor Stage III Mantle Cell Lymphoma; Ann Arbor Stage IV Mantle Cell Lymphoma |
National Cancer Institute (NCI) |
2026-10-30 | PHASE1 |
| NCT07451912 | RECRUITING | Acute Myeloid Leukemia (AML); CEBPA Mutation; Unfit, New-diagnosis AML |
The First Affiliated Hospital of Soochow University |
2025-09-15 | PHASE1; PHASE2 |
| NCT06529250 | RECRUITING | AML |
Institute of Hematology & Blood Diseases Hospital, China |
2024-08-13 | |
| NCT07108530 | RECRUITING | Acute Myeloid Leukemia |
Shanxi Bethune Hospital |
2025-08-06 | PHASE2 |
| NCT06533761 | RECRUITING | AML, Adult; MDS |
Stelexis BioSciences |
2025-04-28 | PHASE1 |
| NCT04050280 | RECRUITING | Acute Myeloid Leukemia, Adult; Acute Myeloid Leukemia Recurrent; Acute Myeloid Leukemia, Relapsed, Adult |
University of Maryland, Baltimore |
2019-11-01 | PHASE2 |
| NCT07032727 | RECRUITING | Targeted Therapy; IDH1-Mutated Malignancies; Mutations |
M.D. Anderson Cancer Center |
2025-09-12 | PHASE2 |
| NCT03897127 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia |
University of Ulm |
2019-09-04 | PHASE3 |
| NCT03793478 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia |
Daiichi Sankyo |
2018-08-15 | PHASE1; PHASE2 |
| NCT06895473 | RECRUITING | Hematopoietic and Lymphatic System Neoplasm |
OHSU Knight Cancer Institute |
2025-06-04 | PHASE2 |
| NCT07187193 | RECRUITING | Langerhans Cell Histiocytosis |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2025-04-12 | PHASE2 |
| NCT07537257 | ENROLLING_BY_INVITATION | AML (Acute Myelogenous Leukemia) |
Guangdong Second Provincial General Hospital |
2026-04-01 | PHASE2; PHASE3 |
| NCT04385290 | RECRUITING | Acute Myeloid Leukemia |
Technische Universität Dresden |
2020-09-04 | PHASE1; PHASE2 |
| NCT05554406 | RECRUITING | Acute Myeloid Leukemia; Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm; Acute Myeloid Leukemia Post Cytotoxic Therapy; Acute Myeloid Leukemia, Myelodysplasia-Related |
National Cancer Institute (NCI) |
2024-09-25 | PHASE2 |
| NCT03710772 | ACTIVE_NOT_RECRUITING | Mantle Cell Lymphoma |
M.D. Anderson Cancer Center |
2019-05-01 | PHASE2 |
| NCT06313437 | RECRUITING | Acute Myeloid Leukemia; AML, Adult; AML With Gene Mutations; AML; Leukemia |
Richard Stone, MD |
2024-12-06 | PHASE1 |
| NCT04375631 | RECRUITING | Recurrent Acute Myeloid Leukemia; Recurrent Chronic Myelomonocytic Leukemia; Recurrent Myelodysplastic Syndrome; Refractory Acute Myeloid Leukemia; Refractory Chronic Myelomonocytic Leukemia; Refractory Mixed Phenotype Acute Leukemia; Refractory Myelodysplastic Syndrome; Refractory Acute Leukemia of Ambiguous Lineage; Refractory Acute Undifferentiated Leukemia |
Fred Hutchinson Cancer Center |
2020-12-03 | PHASE1 |
| NCT05183035 | RECRUITING | Acute Myeloid Leukemia |
PedAL BCU, LLC |
2022-10-01 | PHASE3 |
| NCT04801797 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia |
Massachusetts General Hospital |
2021-05-20 | PHASE2 |
| NCT06345365 | RECRUITING | Acute Myeloid Leukaemia |
Zhongnan Hospital |
2024-01-18 | PHASE3 |
| NCT05603884 | RECRUITING | Leukemia, Myeloid, Acute; AML Stage, Adult |
The First Affiliated Hospital of Xiamen University |
2022-12-01 | PHASE2 |
| NCT05681260 | RECRUITING | T-cell Lymphoblastic Lymphoma |
Children's Cancer Group, China |
2023-02-06 | PHASE3 |
| NCT02981628 | ACTIVE_NOT_RECRUITING | Recurrent B Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory B Lymphoblastic Lymphoma |
Children's Oncology Group |
2017-06-19 | PHASE2 |
| NCT04049539 | RECRUITING | Blasts More Than 5 Percent of Bone Marrow Nucleated Cells; Persistent Disease; Refractory Acute Myeloid Leukemia |
Ohio State University Comprehensive Cancer Center |
2021-01-29 | PHASE1; PHASE2 |
| NCT07156435 | RECRUITING | Relapsed Pediatric AML; Refractory Pediatric AML |
Princess Maxima Center for Pediatric Oncology |
2020-11-06 | PHASE1 |
| NCT06651866 | RECRUITING | Acute Myeloid Leukemia |
The First Affiliated Hospital of Xiamen University |
2024-12-12 | PHASE1 |
| NCT03330821 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Acute Myeloid Leukemia With Myelodysplasia-Related Changes; Therapy-Related Acute Myeloid Leukemia |
University of Southern California |
2018-04-18 | PHASE1; PHASE2 |
| NCT04115631 | ACTIVE_NOT_RECRUITING | Liver Lymphoma; Mantle Cell Lymphoma |
ECOG-ACRIN Cancer Research Group |
2019-12-13 | PHASE2 |
| NCT06451861 | RECRUITING | Acute Myeloid Leukemia |
Guangdong Provincial People's Hospital |
2024-08-21 | PHASE2 |
| NCT06001788 | RECRUITING | AML; AML With Mutated NPM1; Hematologic Malignancy; KMT2Ar; NPM1 Mutation; MLL Rearrangement; Leukemia; Acute Myeloid Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Acute Leukemia; Neoplasms by Histologic Type |
Kura Oncology, Inc. |
2024-02-22 | PHASE1 |
| NCT06520176 | RECRUITING | Multiple Myeloma; Hematopoietic Stem Cell Mobilization |
The Affiliated People's Hospital of Ningbo University |
2024-08 | PHASE3 |
| NCT02877303 | RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2016-11-01 | PHASE2 |
| NCT06741722 | RECRUITING | AML; Relapsed Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia |
Beijing 302 Hospital |
2024-10-31 | PHASE2 |
| NCT00501826 | RECRUITING | T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2007-07-11 | PHASE2 |
| NCT07490288 | RECRUITING | AML |
Institute of Hematology & Blood Diseases Hospital, China |
2026-05-08 | |
| NCT05453903 | ACTIVE_NOT_RECRUITING | Leukemia, Myeloid, Acute |
Janssen Research & Development, LLC |
2022-10-04 | PHASE1 |
| NCT03117751 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Acute Lymphoblastic Lymphoma |
St. Jude Children's Research Hospital |
2017-03-29 | PHASE2; PHASE3 |
| NCT06210750 | WITHDRAWN | T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
National Cancer Institute (NCI) |
2024-08-09 | PHASE2 |
| NCT05521087 | WITHDRAWN | Acute Leukemias; Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia; Acute Leukemia of Ambiguous Lineage |
Janssen Research & Development, LLC |
2025-12-26 | PHASE1 |
| NCT02203526 | ACTIVE_NOT_RECRUITING | Primary Central Nervous System Lymphoma |
National Cancer Institute (NCI) |
2014-08-14 | PHASE1 |
| NCT07244367 | RECRUITING | Acute Myeloid Leukaemia (AML) |
Sohag University |
2025-09-01 | |
| NCT05554419 | NOT_YET_RECRUITING | Acute Myeloid Leukemia; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Acute Myeloid Leukemia Arising From Previous Myeloproliferative Neoplasm; Acute Myeloid Leukemia Post Cytotoxic Therapy; Secondary Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2026-07-01 | PHASE2 |
| NCT06554626 | RECRUITING | Precursor B-Cell Lymphoblastic Leukemia |
First Affiliated Hospital of Zhejiang University |
2024-08-15 | PHASE2 |
| NCT06520163 | RECRUITING | Non-Hodgkin's Lymphoma; Hematopoietic Stem Cell Mobilization |
The Affiliated People's Hospital of Ningbo University |
2024-08-01 | PHASE3 |
| NCT03672539 | COMPLETED | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Chronic Myelomonocytic Leukemia; High Risk Myelodysplastic Syndrome; Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2018-11-07 | PHASE2 |
| NCT06537843 | RECRUITING | Acute Myeloid Leukemia |
Hospital Municipal São José |
2023-12-01 | PHASE2 |
| NCT06742463 | RECRUITING | Acute T Lymphpblastic Leukemia/Lymphoma |
First Affiliated Hospital of Zhejiang University |
2024-12 | PHASE2 |
| NCT05939180 | RECRUITING | Acute Myeloid Leukemia |
The First Affiliated Hospital of Soochow University |
2024-04-01 | PHASE2; PHASE3 |
| NCT03031249 | ENROLLING_BY_INVITATION | AML |
Institute of Hematology & Blood Diseases Hospital, China |
2017-02-08 | PHASE1; PHASE2 |
| NCT03021330 | ACTIVE_NOT_RECRUITING | AML |
Institute of Hematology & Blood Diseases Hospital, China |
2017-02-08 | PHASE3 |
| NCT04217278 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukaemia; High-risk Myelodysplastic Syndrome |
University of Birmingham |
2020-01-27 | PHASE2; PHASE3 |
| NCT03258931 | COMPLETED | Newly Diagnosed FLT3 Mutated AML |
Arog Pharmaceuticals, Inc. |
2018-08-15 | PHASE3 |
| NCT03250338 | COMPLETED | Relapsed/Refractory Acute Myeloid Leukemia With FLT3 Activating Mutations |
Arog Pharmaceuticals, Inc. |
2018-08-16 | PHASE3 |
| NCT04547049 | ACTIVE_NOT_RECRUITING | Leukemia; MDS |
First Affiliated Hospital of Zhejiang University |
2020-09-01 | PHASE3 |
| NCT07651475 | ACTIVE_NOT_RECRUITING | R/R AML |
Liping Dou |
2026-03-31 | PHASE2 |
| NCT02723994 | COMPLETED | Leukemia |
Incyte Corporation |
2016-09-30 | PHASE2 |
| NCT04061239 | RECRUITING | MDS; AML |
GWT-TUD GmbH |
2019-08-19 | PHASE2 |
| NCT04275518 | RECRUITING | Acute Myeloid Leukemia (AML); Myelodysplastic Syndromes (MDS) |
Ascentage Pharma Group Inc. |
2020-07-06 | PHASE1 |
| NCT05241093 | UNKNOWN | Relapsed or Refractory Acute Myeloid Leukemia (AML) |
Tarapeutics Science Inc. |
2022-03-29 | PHASE2 |
| NCT05466318 | UNKNOWN | Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell |
Sichuan University |
2022-07-01 | PHASE3 |
| NCT00716066 | ACTIVE_NOT_RECRUITING | Autoimmune Disease; Neurologic Autoimmune Disease; Autologous Transplant Autoimmune; Multiple Sclerosis Transplant; MS Stem Cell Transplant; Multiple Sclerosis Stem Cell Transplant; Stiff Person Syndrome; HCT for Neurologic Autoimmune Disorders; CIDP Transplant; Myasthenia Gravis Transplant; Autoimmune Nervous System Disorder; Central Nervous System Vasculitis; Cerebellar Degeneration; Chronic Inflammatory Demyelinating Polyneuropathy; Lambert Eaton Myasthenic Syndrome; Myasthenia Gravis; Neuromyelitis Optica; Opsoclonus Myoclonus Syndrome; Rasmussen Subacute Encephalitis |
Fred Hutchinson Cancer Center |
2008-06 | PHASE2 |
| NCT06007911 | WITHDRAWN | Relapsed Adult AML; Refractory AML |
Medical College of Wisconsin |
2024-08-31 | PHASE1 |
| NCT04229979 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia |
Sellas Life Sciences Group |
2021-02-08 | PHASE3 |
| NCT04968015 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia |
French Innovative Leukemia Organisation |
2022-05-25 | PHASE2 |
| NCT06697327 | ENROLLING_BY_INVITATION | Leukemia, Myeloid, Acute; Acute Myeloid Leukemia |
Anhui Medical University |
2025-02-01 | |
| NCT02416388 | RECRUITING | Acute Myeloid Leukemia (AML) |
University Hospital, Angers |
2015-01 | PHASE2; PHASE3 |
| NCT06434662 | UNKNOWN | Relapsed/Refractory Acute Myeloid Leukaemia; Myeloid Malignancy |
First Affiliated Hospital of Zhejiang University |
2024-02-29 | PHASE2 |
| NCT04269213 | COMPLETED | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Acute Myeloid Leukemia With Myelodysplasia-Related Changes; Secondary Acute Myeloid Leukemia; Therapy-Related Acute Myeloid Leukemia |
Roswell Park Cancer Institute |
2021-07-29 | PHASE2 |
| NCT03150004 | TERMINATED | Acute Myeloid Leukemia; Myelodysplastic Syndrome |
Medical College of Wisconsin |
2017-06-14 | PHASE2 |
| NCT03878199 | TERMINATED | Essential Thrombocythemia; Myelofibrosis; Myeloproliferative Neoplasm; Polycythemia Vera; Secondary Acute Myeloid Leukemia |
Ohio State University Comprehensive Cancer Center |
2019-02-20 | PHASE1; PHASE2 |
| NCT02688140 | COMPLETED | Acute Promyelocytic Leukemia |
Technische Universität Dresden |
2016-06 | PHASE3 |
| NCT05987696 | COMPLETED | AML, Adult; Minimal Residual Disease |
Institute of Hematology & Blood Diseases Hospital, China |
2023-07-31 | PHASE1 |
| NCT05662956 | COMPLETED | Acute Myeloid Leukemia |
Hematology department of the 920th hospital |
2022-12-01 | PHASE2 |
| NCT01593488 | UNKNOWN | Acute Lymphoblastic Leukemia |
National Cancer Institute, Naples |
2012-03 | PHASE2 |
| NCT04687761 | COMPLETED | Leukemia, Myeloid, Acute; De Novo; Age More 60yr |
PETHEMA Foundation |
2020-11-04 | PHASE1; PHASE2 |
| NCT04848974 | COMPLETED | Secondary Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2021-06-11 | PHASE1; PHASE2 |
| NCT04880746 | UNKNOWN | Peripheral T-cell Lymphoma |
Ruijin Hospital |
2020-10-17 | PHASE3 |
| NCT04107727 | COMPLETED | Acute Myeloid Leukemia |
PETHEMA Foundation |
2019-09-05 | PHASE2 |
| NCT03825796 | ACTIVE_NOT_RECRUITING | Recurrent Acute Myeloid Leukemia |
Jonsson Comprehensive Cancer Center |
2019-04-12 | PHASE2 |
| NCT05598593 | UNKNOWN | Cytarabine+Thiotepa + Fludarabine + Busulfan; T Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma |
First Affiliated Hospital of Zhejiang University |
2022-10-23 | PHASE2 |
| NCT05805072 | UNKNOWN | Relapsed/Refractory AML |
The First Affiliated Hospital of Soochow University |
2023-05-01 | |
| NCT02521493 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia; Down Syndrome; Myelodysplastic Syndrome; Myeloid Leukemia Associated With Down Syndrome; Myeloproliferative Neoplasm |
Children's Oncology Group |
2015-12-23 | PHASE3 |
| NCT00878254 | COMPLETED | Mantle-Cell Lymphoma |
University of Miami |
2009-03-25 | PHASE2 |
| NCT05536154 | UNKNOWN | Lymphoma; Multiple Myeloma |
The Affiliated People's Hospital of Ningbo University |
2022-11-01 | |
| NCT03569995 | UNKNOWN | Primary CNS Lymphoma |
Won Seog Kim |
2018-11-30 | PHASE2 |
| NCT05510089 | UNKNOWN | Hematological Malignancy |
The Affiliated People's Hospital of Ningbo University |
2022-09-01 | |
| NCT06068621 | COMPLETED | Acute Myeloid Leukemia |
Chinese PLA General Hospital |
2023-03-01 | PHASE2 |
| NCT04029688 | TERMINATED | Acute Myeloid Leukemia (AML); Acute Lymphoblastic Leukemia (ALL); Neuroblastoma; Solid Tumors |
Hoffmann-La Roche |
2020-01-27 | PHASE1; PHASE2 |
| NCT05177731 | ACTIVE_NOT_RECRUITING | AML, Adult; Chemotherapy Effect |
Chen Suning |
2022-03-01 | PHASE3 |
| NCT05712278 | TERMINATED | Acute Myeloid Leukaemia |
Sanofi |
2023-06-16 | PHASE1 |
| NCT00390793 | COMPLETED | Acute Lymphoblastic Leukemia; BCR-ABL1 Fusion Protein Expression; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Philadelphia Chromosome Positive; Recurrent Acute Lymphoblastic Leukemia; t(9;22) |
M.D. Anderson Cancer Center |
2006-09-28 | PHASE2 |
| NCT02392429 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2016-04-20 | PHASE2 |
| NCT04956042 | TERMINATED | Refractory Acute Myeloid Leukemia; Recurrent Acute Myeloid Leukemia |
CicloMed LLC |
2021-08-27 | PHASE1; PHASE2 |
| NCT05665075 | UNKNOWN | AML, Adult |
Zhejiang University |
2022-12-24 | PHASE1 |
| NCT03817320 | ACTIVE_NOT_RECRUITING | ALL, Childhood; Lymphoblastic Lymphoma, Childhood; Lymphoblastic Leukemia, Acute, Childhood |
Therapeutic Advances in Childhood Leukemia Consortium |
2019-02-12 | PHASE1; PHASE2 |
| NCT04112589 | UNKNOWN | Acute Myeloid Leukemia |
PETHEMA Foundation |
2019-12-26 | PHASE1; PHASE2 |
| NCT03026842 | UNKNOWN | Acute Myeloid Leukemia |
The First Hospital of Jilin University |
2017-01 | PHASE4 |
| NCT03904251 | TERMINATED | Acute Myelogenous Leukemia |
Jonsson Comprehensive Cancer Center |
2019-07-18 | PHASE1 |
| NCT03654716 | COMPLETED | Leukemia; Brain Tumor; Solid Tumor; Lymphoma |
Dana-Farber Cancer Institute |
2018-11-01 | PHASE1 |
| NCT04773366 | UNKNOWN | Langerhans Cell Histiocytosis |
Shanghai Children's Medical Center |
2018-07-01 | PHASE3 |
| NCT05601830 | TERMINATED | Minimal Residual Disease |
Institute of Hematology & Blood Diseases Hospital, China |
2022-10-09 | PHASE1 |
| NCT05362942 | UNKNOWN | Relapsed Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia; Minimal Residual Disease |
Beijing 302 Hospital |
2022-05-01 | PHASE2 |
| NCT04083066 | UNKNOWN | Primary Central Nervous System Lymphoma |
Mingzhi Zhang |
2019-09-05 | PHASE4 |
| NCT04797182 | UNKNOWN | Thrombocytopenia; Cytarabine Causing Adverse Effects in Therapeutic Use; Lymphoma |
Sun Yat-sen University |
2021-04 | PHASE2 |
| NCT05020665 | TERMINATED | Nucleophosmin 1-mutated Acute Myeloid Leukemia |
Kronos Bio |
2021-11-24 | PHASE3 |
| NCT03412266 | UNKNOWN | Myelodysplastic Syndromes |
Peking University People's Hospital |
2018-02-01 | PHASE2 |
| NCT05697510 | Recruiting | Acute Myeloid Leukemia (AML) |
Nantes University Hospital |
2023-03-16 | Phase 1 |
| NCT01892371 | COMPLETED | FLT3 Gene Mutation Negative; FLT3 Internal Tandem Duplication Positive; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Myelomonocytic Leukemia; Recurrent Myelodysplastic Syndrome; Refractory Acute Myeloid Leukemia; Refractory Chronic Myelomonocytic Leukemia; Refractory Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2013-11-12 | PHASE1; PHASE2 |
| NCT05372536 | COMPLETED | Supportive Care; Childhood Cancer |
Rigshospitalet, Denmark |
2022-02-01 | |
| NCT03878927 | TERMINATED | Acute Myeloid Leukemia |
Weill Medical College of Cornell University |
2019-08-23 | PHASE1 |
| NCT03589326 | ACTIVE_NOT_RECRUITING | Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL) |
Takeda |
2018-10-04 | PHASE3 |
| NCT03384225 | UNKNOWN | High Risk Acute Myeloid Leukemia; Allogeneic Hematopoeitic Stem Cell Transplantation |
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine |
2016-08-01 | PHASE3 |
| NCT02553460 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia |
St. Jude Children's Research Hospital |
2016-01-29 | PHASE1; PHASE2 |
| NCT02043587 | TERMINATED | Acute Lymphocytic Leukemia; Adult Lymphoblastic Lymphoma |
University of California, San Diego |
2014-01 | PHASE2 |
| NCT04402723 | TERMINATED | Acute Myeloid Leukemia (AML) |
Suzhou Zelgen Biopharmaceuticals Co.,Ltd |
2018-11-06 | PHASE1 |
| NCT02728050 | COMPLETED | Acute Biphenotypic Leukemia; Acute Myeloid Leukemia; de Novo Myelodysplastic Syndrome; Myelodysplastic Syndrome; Myeloproliferative Neoplasm |
University of Washington |
2016-12-01 | PHASE1; PHASE2 |
| NCT02523976 | COMPLETED | Acute,Leukemia, Lymphoid |
Institute of Hematology & Blood Diseases Hospital, China |
2015-08-01 | PHASE2 |
| NCT03988205 | TERMINATED | Leukemia, Myeloid, Acute |
Medical College of Wisconsin |
2019-08-28 | PHASE4 |
| NCT04069208 | UNKNOWN | Acute Myeloid Leukemia |
Peking Union Medical College Hospital |
2019-09-03 | PHASE2 |
| NCT03504410 | TERMINATED | Relapsed/Refractory Acute Myeloid Leukemia |
Cornerstone Pharmaceuticals |
2018-11-12 | PHASE3 |
| NCT04196010 | TERMINATED | Myeloid Neoplasm; Recurrent Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia |
University of Washington |
2020-05-08 | PHASE1 |
| NCT03813147 | COMPLETED | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Myelodysplastic Syndrome; Refractory Acute Myeloid Leukemia; Refractory Myelodysplastic Syndrome |
National Cancer Institute (NCI) |
2019-05-17 | PHASE1 |
| NCT02741388 | COMPLETED | B-cell Lymphoma |
The Lymphoma Academic Research Organisation |
2016-10 | PHASE1 |
| NCT03882203 | COMPLETED | Refractory Hematologic Cancer; Allogeneic Stem Cell Transplantation |
Shanghai Jiao Tong University School of Medicine |
2018-08-01 | PHASE2 |
| NCT02310321 | COMPLETED | Acute Myeloid Leukemia; FLT3-mutated Acute Myeloid Leukemia |
Astellas Pharma Inc |
2015-02-26 | PHASE1; PHASE2 |
| NCT03349281 | COMPLETED | Refractory Acute Lymphoblastic Leukemia; Relapsed Acute Lymphoblastic Leukemia |
Julio Barredo, MD |
2019-03-25 | PHASE1 |
| NCT02287233 | COMPLETED | Acute Myelogenous Leukemia; AML |
AbbVie |
2014-12-31 | PHASE1; PHASE2 |
| NCT03446638 | WITHDRAWN | Myelodysplastic Syndromes |
University of Florida |
2019-05 | |
| NCT04109690 | WITHDRAWN | MDS |
Yale University |
2019-12-30 | PHASE1; PHASE2 |
| NCT02236013 | COMPLETED | Acute Myeloid Leukemia |
Astellas Pharma Global Development, Inc. |
2015-01-07 | PHASE1 |
| NCT03379727 | COMPLETED | Acute Myeloid Leukemia |
Novartis Pharmaceuticals |
2018-02-13 | PHASE3 |
| NCT04920500 | UNKNOWN | Acute Myeloid Leukemia |
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. |
2020-09-04 | |
| NCT03459859 | COMPLETED | Acute Myelogenous Leukemia; AML; Advanced Myelodysplastic Syndromes; MDS |
Justin Watts, MD |
2018-05-21 | PHASE1 |
| NCT04083911 | UNKNOWN | Acute Myeloid Leukemia; Induction Chemotherapy |
The First Affiliated Hospital of Soochow University |
2019-04-01 | PHASE3 |
| NCT03564704 | UNKNOWN | Leukemia; Leukemia, Acute; Adult Lymphoblastic Lymphoma; Leukemia, Lymphoblastic; Leukemia, T Cell; Adult Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma; Lymphoblastic Leukemia |
Nanfang Hospital, Southern Medical University |
2016-02-14 | PHASE2; PHASE3 |
| NCT03555955 | COMPLETED | Hematologic Malignancy; Acute Myeloid Leukemia; Acute Lymphocytic Leukemia; Acute Lymphoblastic Leukemia; Myelodysplastic Syndromes |
Jazz Pharmaceuticals |
2018-11-20 | PHASE1 |
| NCT02718755 | WITHDRAWN | Hematologic Malignancy |
M.D. Anderson Cancer Center |
2018-05 | PHASE2 |
| NCT03969420 | TERMINATED | Acute Myeloid Leukemia (AML) |
Sumitomo Pharma America, Inc. |
2020-01-15 | PHASE2 |
| NCT04509622 | COMPLETED | Acute Myeloid Leukemia (AML) |
AbbVie |
2020-10-05 | PHASE3 |
| NCT02085408 | COMPLETED | Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome; Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Secondary Acute Myeloid Leukemia; Untreated Adult Acute Myeloid Leukemia |
ECOG-ACRIN Cancer Research Group |
2011-02-04 | PHASE3 |
| NCT02038777 | COMPLETED | Acute Myeloid Leukemia |
Pfizer |
2014-03-25 | PHASE1 |
| NCT03207334 | WITHDRAWN | Acute Myeloid Leukemia |
University of Florida |
2018-11 | PHASE2 |
| NCT01511562 | ACTIVE_NOT_RECRUITING | Lymphoma |
Alliance for Clinical Trials in Oncology |
2012-09 | PHASE2 |
| NCT02717884 | UNKNOWN | Acute Myeloid Leukemia; Myelodysplastic Syndrome |
Michael Luebbert |
2015-05 | PHASE1; PHASE2 |
| NCT02339740 | ACTIVE_NOT_RECRUITING | Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2); PML-RARA |
Children's Oncology Group |
2015-07-21 | PHASE3 |
| NCT00477412 | COMPLETED | Mantle Cell Lymphoma |
M.D. Anderson Cancer Center |
2007-04-03 | PHASE1; PHASE2 |
| NCT03194932 | COMPLETED | Acute Myeloid Leukemia |
St. Jude Children's Research Hospital |
2017-07-11 | PHASE1 |
| NCT03568994 | COMPLETED | Acute Myeloid Leukemia |
Baylor College of Medicine |
2018-07-10 | EARLY_PHASE1 |
| NCT00549848 | COMPLETED | Acute Lymphoblastic Leukemia |
St. Jude Children's Research Hospital |
2007-10-29 | PHASE3 |
| NCT02342782 | COMPLETED | Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma; Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma; Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma; Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma; Refractory Cutaneous T-Cell Non-Hodgkin Lymphoma |
City of Hope Medical Center |
2020-06-08 | PHASE1 |
| NCT03850535 | TERMINATED | Acute Myeloid Leukemia |
Hoffmann-La Roche |
2019-03-25 | PHASE1; PHASE2 |
| NCT03263936 | COMPLETED | Acute Myelogenous Leukemia |
Therapeutic Advances in Childhood Leukemia Consortium |
2017-07-11 | PHASE1 |
| NCT03416179 | COMPLETED | Leukemia, Myeloid, Acute |
Pfizer |
2018-04-20 | PHASE3 |
| NCT01859819 | COMPLETED | Diffuse Large Cell Lymphoma; Burkitt's Lymphoma; High Grade B-cell Lymphoma |
New York Medical College |
2013-01 | PHASE2 |
| NCT02029950 | COMPLETED | Acute Myeloid Leukemia; Chronic Myelomonocytic Leukemia-2; High Risk Myelodysplastic Syndrome; Myeloproliferative Neoplasm |
National Cancer Institute (NCI) |
2013-12-16 | PHASE1 |
| NCT00968760 | COMPLETED | Lymphoma; B-cell Lymphoma |
M.D. Anderson Cancer Center |
2011-06-20 | PHASE1 |
| NCT01363128 | COMPLETED | Acute Lymphoblastic Leukemia; Adult Acute Lymphoblastic Leukemia in Complete Remission; Burkitt Leukemia; Burkitt Lymphoma; CD20 Positive; Childhood Acute Lymphoblastic Leukemia in Complete Remission; Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2011-07-12 | PHASE2 |
| NCT04100330 | WITHDRAWN | Acute Myeloid Leukemia |
AVEO Pharmaceuticals, Inc. |
2020-01-31 | PHASE2 |
| NCT02416206 | COMPLETED | Multiple Myeloma |
Northside Hospital, Inc. |
2015-04-27 | PHASE2 |
| NCT03298984 | COMPLETED | Acute Myeloid Leukemia |
Sumitomo Pharma America, Inc. |
2017-09-25 | PHASE1 |
| NCT00591630 | COMPLETED | Diffuse Large Cell Lymphoma; Lymphoma |
M.D. Anderson Cancer Center |
2007-11-14 | PHASE2 |
| NCT01788189 | COMPLETED | B-cell Lymphoma |
University Hospital, Essen |
2013-01 | PHASE1; PHASE2 |
| NCT01822015 | COMPLETED | Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Untreated Adult Acute Myeloid Leukemia |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2013-03-15 | EARLY_PHASE1 |
| NCT02858804 | COMPLETED | Mantle Cell Lymphoma |
Institute of Hematology & Blood Diseases Hospital, China |
2016-01 | PHASE4 |
| NCT02283177 | COMPLETED | Newly Diagnosed AML With FLT3 Activating Mutations |
Arog Pharmaceuticals, Inc. |
2015-01 | PHASE2 |
| NCT02576301 | UNKNOWN | Acute Myelogenous Leukemia; Myelodysplastic Syndromes |
Mateon Therapeutics |
2015-10 | PHASE1; PHASE2 |
| NCT03118466 | COMPLETED | AML |
Massachusetts General Hospital |
2017-09-25 | PHASE2 |
| NCT01839240 | COMPLETED | Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Untreated Adult Acute Myeloid Leukemia |
University of Chicago |
2012-06-06 | PHASE1 |
| NCT03444649 | WITHDRAWN | AML |
Insel Gruppe AG, University Hospital Bern |
2018-09 | PHASE1 |
| NCT02652871 | COMPLETED | Leukemia |
M.D. Anderson Cancer Center |
2016-05-09 | PHASE1 |
| NCT03661515 | COMPLETED | Acute Myeloid Leukemia |
PETHEMA Foundation |
2018-07-17 | PHASE1 |
| NCT02280525 | COMPLETED | Leukemia |
M.D. Anderson Cancer Center |
2015-03-05 | PHASE1 |
| NCT01636609 | TERMINATED | Acute Myeloid Leukemia; High Risk Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2012-11-20 | PHASE1 |
| NCT02791919 | WITHDRAWN | CNS 2a; CNS 2b; CNS 2c; CNS1; Recurrent Adult Acute Myeloid Leukemia; Recurrent Childhood Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2017-05-25 | PHASE1 |
| NCT03071276 | TERMINATED | Acute Myeloid Leukemia (AML) |
St. Jude Children's Research Hospital |
2016-01-14 | PHASE2 |
| NCT02909972 | COMPLETED | Acute Myeloid Leukemia; Myelodysplastic Syndromes |
Aileron Therapeutics, Inc. |
2016-09 | PHASE1 |
| NCT01190930 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Lymphoblastic Lymphoma; Ann Arbor Stage I B Lymphoblastic Lymphoma; Ann Arbor Stage II B Lymphoblastic Lymphoma; Childhood B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Childhood B Lymphoblastic Lymphoma; Down Syndrome; Hypodiploid B Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive |
Children's Oncology Group |
2010-08-11 | PHASE3 |
| NCT03735446 | TERMINATED | Acute Myeloid Leukemia; Myelodysplastic Syndromes |
Dana-Farber Cancer Institute |
2019-01-18 | PHASE1 |
| NCT03135028 | TERMINATED | Hematologic Malignancy; Acute Myeloid Leukemia |
Gilead Sciences |
2017-05-19 | PHASE1 |
| NCT02728531 | COMPLETED | Mantle Cell Lymphoma |
Washington University School of Medicine |
2016-04-18 | PHASE1 |
| NCT02243436 | COMPLETED | CLASSICAL HODGKIN LYMPHOMA |
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea |
2014-11-11 | PHASE1; PHASE2 |
| NCT02642965 | COMPLETED | Acute Myeloid Leukemia Post Cytotoxic Therapy; Recurrent Childhood Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia |
Children's Oncology Group |
2016-05-02 | PHASE1; PHASE2 |
| NCT03259516 | TERMINATED | Myelodysplastic Syndromes |
St. Petersburg State Pavlov Medical University |
2017-05-25 | PHASE1; PHASE2 |
| NCT02440568 | TERMINATED | Acute Myeloid Leukemia |
University of Illinois at Chicago |
2015-06-05 | PHASE1; PHASE2 |
| NCT02575963 | COMPLETED | AML |
Actinium Pharmaceuticals |
2012-10 | PHASE1; PHASE2 |
| NCT02921061 | COMPLETED | Mixed Phenotype Acute Leukemia; Previously Treated Myelodysplastic Syndrome; Recurrent Adult Acute Myeloid Leukemia; Recurrent High Risk Myelodysplastic Syndrome; Refractory Acute Myeloid Leukemia; Refractory High Risk Myelodysplastic Syndrome; Untreated Adult Acute Myeloid Leukemia |
Fred Hutchinson Cancer Center |
2016-11-17 | PHASE1; PHASE2 |
| NCT00732498 | COMPLETED | Lymphoma |
University of Arizona |
2006-05-15 | PHASE2 |
| NCT02894645 | UNKNOWN | Acute Lymphoblastic Leukemia (ALL) |
National University Hospital, Singapore |
2008-10 | PHASE4 |
| NCT02343939 | TERMINATED | Acute Myeloid Leukemia |
Gilead Sciences |
2015-07-01 | PHASE1; PHASE2 |
| NCT01645839 | COMPLETED | Breast Cancer; Leptomeningeal Metastases |
Centre Oscar Lambret |
2011-08-30 | PHASE3 |
| NCT00866749 | COMPLETED | Lymphoblastic Leukemia; Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2006-09-12 | PHASE2 |
| NCT01497002 | COMPLETED | Acute Myeloid Leukaemia |
University of Leipzig |
2005-04 | PHASE3 |
| NCT02432872 | UNKNOWN | Acute Myeloid Leukemia |
Jianxiang Wang |
2015-04 | |
| NCT02432911 | UNKNOWN | Acute Myeloid Leukemia |
Jianxiang Wang |
2015-04 | |
| NCT01876953 | TERMINATED | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Recurrent Adult Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Untreated Adult Acute Myeloid Leukemia |
City of Hope Medical Center |
2013-09-13 | PHASE1; PHASE2 |
| NCT02676323 | TERMINATED | Acute Myeloid Leukemia; Myelodysplastic Syndrome |
St. Jude Children's Research Hospital |
2016-05-03 | PHASE1 |
| NCT01830777 | COMPLETED | Acute Myelogenous Leukemia |
Massachusetts General Hospital |
2013-05 | PHASE1 |
| NCT01187810 | TERMINATED | Acute Myelogenous Leukemia; Acute Lymphoblastic Leukemia; Non-Hodgkin's Lymphoma |
South Plains Oncology Consortium |
2010-08 | PHASE1 |
| NCT02686593 | COMPLETED | Acute Myeloid Leukemia |
The University of Hong Kong |
2016-02-01 | PHASE2 |
| NCT02626338 | COMPLETED | Relapsed/Refractory Acute Myeloid Leukemia (AML) |
Arog Pharmaceuticals, Inc. |
2016-02 | PHASE1; PHASE2 |
| NCT01794702 | COMPLETED | Leukemia |
M.D. Anderson Cancer Center |
2013-02-20 | PHASE1; PHASE2 |
| NCT02573363 | COMPLETED | Acute Myeloid Leukemia |
University of Chicago |
2015-10-07 | PHASE1 |
| NCT03337516 | UNKNOWN | Acute Myeloid Leukemia |
Assistance Publique Hopitaux De Marseille |
2017-06-21 | |
| NCT02130869 | COMPLETED | Neuroblastoma; Lymphoma; High-risk Tumor |
St. Jude Children's Research Hospital |
2014-10-10 | PHASE1 |
| NCT02293109 | COMPLETED | Contiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia |
Mehrdad Abedi, MD |
2015-12-17 | PHASE1 |
| NCT02306291 | COMPLETED | Leukemia, Myeloid, Acute |
GlycoMimetics Incorporated |
2015-03 | PHASE1; PHASE2 |
| NCT01156883 | COMPLETED | Leukemia |
Gruppo Italiano Malattie EMatologiche dell'Adulto |
2010-04 | |
| NCT02834390 | COMPLETED | Acute Myeloid Leukemia |
Daiichi Sankyo Co., Ltd. |
2016-08-12 | PHASE1 |
| NCT02560025 | COMPLETED | Acute Myeloid Leukemia |
Massachusetts General Hospital |
2015-12 | PHASE2 |
| NCT01806571 | COMPLETED | Untreated Adult Acute Myeloid Leukemia |
Mayo Clinic |
2015-03-12 | PHASE2 |
| NCT02635074 | TERMINATED | Recurrent Adult Acute Myeloid Leukemia |
Steven E. Coutre |
2016-11 | PHASE1 |
| NCT01555541 | COMPLETED | Diffuse Large Cell Lymphoma Relapsed/Refractory |
C. Babis Andreadis |
2012-05-25 | PHASE2 |
| NCT01481272 | COMPLETED | Diffuse Large B Cell Lymphoma |
Polish Lymphoma Research Group |
2011-11 | PHASE2 |
| NCT02419469 | TERMINATED | Leukemia; Precursor-B Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma; Lymphoma |
M.D. Anderson Cancer Center |
2015-11-13 | PHASE2 |
| NCT01692197 | COMPLETED | Leukemia |
M.D. Anderson Cancer Center |
2013-02-01 | PHASE2 |
| NCT02277847 | UNKNOWN | Acute Myeloid Leukemia |
Guangdong Provincial People's Hospital |
2010-03 | PHASE4 |
| NCT02433483 | TERMINATED | Acute Myeloid Leukemia (AML); Myelodysplastic Syndrome (MDS) |
St. Jude Children's Research Hospital |
2015-05-22 | PHASE2 |
| NCT02229266 | TERMINATED | Acute Myeloid Leukemia |
Technische Universität Dresden |
2015-09 | PHASE2 |
| NCT01588951 | TERMINATED | Acute Myeloid Leukemia |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2013-12 | PHASE2; PHASE3 |
| NCT01804101 | COMPLETED | Acute Biphenotypic Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndrome; Untreated Adult Acute Myeloid Leukemia |
Fred Hutchinson Cancer Center |
2013-05-07 | |
| NCT00422591 | COMPLETED | Leukemia; Acute Myeloid Leukemia; AML |
M.D. Anderson Cancer Center |
2006-12 | PHASE2 |
| NCT02198482 | TERMINATED | Acute Myeloid Leukemia (AML); High-risk Myelodysplastic Syndrome (MDS) |
University of Ulm |
2016-02 | PHASE2 |
| NCT02270788 | COMPLETED | Acute Myeloid Leukemia |
St. Jude Children's Research Hospital |
2015-04-02 | PHASE1 |
| NCT02366663 | TERMINATED | Recurrent Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma |
City of Hope Medical Center |
2015-01 | PHASE3 |
| NCT02472626 | WITHDRAWN | Untreated Adult Acute Myeloid Leukemia |
Wake Forest University Health Sciences |
2015-12 | PHASE1; PHASE2 |
| NCT00840346 | COMPLETED | Acute Myeloblastic Leukaemia |
PETHEMA Foundation |
2009-09 | PHASE1; PHASE2 |
| NCT01435343 | COMPLETED | Acute Myeloblastic Leukemia |
PETHEMA Foundation |
2012-07 | PHASE1; PHASE2 |
| NCT02144675 | COMPLETED | Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia; Untreated Adult Acute Myeloid Leukemia |
Rutgers, The State University of New Jersey |
2009-01 | PHASE2 |
| NCT00920153 | TERMINATED | Lymphoma |
French Innovative Leukemia Organisation |
2008-05 | PHASE3 |
| NCT00381680 | COMPLETED | B-cell Childhood Acute Lymphoblastic Leukemia; L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2007-03 | PHASE3 |
| NCT01999413 | COMPLETED | Acute Myeloid Leukemia (AML) |
French Innovative Leukemia Organisation |
2013-11 | PHASE2 |
| NCT00529360 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myelogenous Leukemia |
New York Medical College |
2007-06 | PHASE1; PHASE2 |
| NCT01768897 | COMPLETED | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Recurrent Adult Acute Myeloid Leukemia |
Wake Forest University Health Sciences |
2013-01 | PHASE1 |
| NCT02105116 | TERMINATED | Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia; Untreated Adult Acute Myeloid Leukemia |
Rutgers, The State University of New Jersey |
2014-02 | |
| NCT00528398 | COMPLETED | Leukemia |
City of Hope Medical Center |
1994-09 | PHASE2 |
| NCT01463046 | COMPLETED | Acute Myeloid Leukemia; Advanced Myelodysplastic Syndrome |
University of California, San Francisco |
2012-01 | PHASE1 |
| NCT00850382 | COMPLETED | Acute Myeloid Leukemia (AML) |
University of Ulm |
2009-06 | PHASE1; PHASE2 |
| NCT02024308 | UNKNOWN | Acute Myeloid Leukemia; AML1-ETO Fusion Protein Expression |
Changhai Hospital |
2010-11 | PHASE4 |
| NCT01779843 | COMPLETED | Acute Myelogenous Leukemia |
Massachusetts General Hospital |
2013-04 | PHASE1 |
| NCT02029417 | TERMINATED | Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome; Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Secondary Acute Myeloid Leukemia; Untreated Adult Acute Myeloid Leukemia |
Roswell Park Cancer Institute |
2014-07 | PHASE2 |
| NCT00669877 | COMPLETED | Burkitt's Lymphoma; Burkitt'S-like Lymphoma |
M.D. Anderson Cancer Center |
2002-08 | PHASE2 |
| NCT00450801 | COMPLETED | Lymphoma |
University of Miami |
2004-04 | PHASE2 |
| NCT01904643 | TERMINATED | Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia |
Stanford University |
2014-02 | PHASE1 |
| NCT01141712 | COMPLETED | Lymphoma; HIV |
Medical College of Wisconsin |
2010-04 | PHASE2 |
| NCT01890746 | COMPLETED | Acute Leukaemia |
Novartis Pharmaceuticals |
2013-09-05 | PHASE2 |
| NCT00295841 | COMPLETED | Leukemia |
Wake Forest University Health Sciences |
2005-02 | PHASE1 |
| NCT00778375 | COMPLETED | Acute Myeloid Leukemia; Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2008-10 | PHASE2 |
| NCT02084563 | COMPLETED | Acute Myeloid Leukemia; Myeloproliferative Neoplasms; Myelodysplastic Syndromes; Myeloproliferative/Myelodysplastic Neoplasm |
Hospital Israelita Albert Einstein |
2012-10 | PHASE2 |
| NCT01178658 | UNKNOWN | Non-Hodgkin Lymphoma |
Seoul National University Hospital |
2010-07 | PHASE2 |
| NCT01880437 | TERMINATED | Myelodysplastic Syndromes, Myelogenous Leukemia, Acute |
Hoffmann-La Roche |
2013-09 | PHASE2 |
| NCT01990807 | UNKNOWN | Childhood Acute Lymphoblastic Leukemia; Philadelphia Chromosome, Ph^1^, Absent; B-cell Childhood Acute Lymphoblastic Leukemia |
Chinese Academy of Medical Sciences |
2012-10 | PHASE4 |
| NCT01721876 | COMPLETED | Leukemia, Myeloid, Acute |
Boehringer Ingelheim |
2013-01-29 | PHASE3 |
| NCT01063439 | UNKNOWN | Non Hodgkin's Lymphoma |
Inje University |
2010-01 | PHASE2 |
| NCT00400946 | COMPLETED | Drug/Agent Toxicity by Tissue/Organ; Leukemia |
Dana-Farber Cancer Institute |
2005-04 | PHASE3 |
| NCT01662050 | COMPLETED | Mantle Cell Lymphoma |
Fondazione Italiana Linfomi - ETS |
2012-03-20 | PHASE2 |
| NCT00038610 | COMPLETED | Leukemia |
M.D. Anderson Cancer Center |
2001-03 | PHASE2 |
| NCT00866307 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2009-02-23 | PHASE1 |
| NCT01127009 | COMPLETED | Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia |
Case Comprehensive Cancer Center |
2010-07 | PHASE1 |
| NCT01242774 | COMPLETED | Acute Myeloid Leukemia (AML) |
Novartis Pharmaceuticals |
2010-10 | PHASE1 |
| NCT00632749 | COMPLETED | Leukemia, Myeloid, Acute |
Boehringer Ingelheim |
2008-05 | PHASE2 |
| NCT00317408 | UNKNOWN | Lymphoma |
European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma |
2004-04 | |
| NCT01132586 | COMPLETED | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11; Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11; Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1; Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL; Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA; Alkylating Agent-Related Acute Myeloid Leukemia; de Novo Myelodysplastic Syndrome; Previously Treated Myelodysplastic Syndrome; Recurrent Adult Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndrome; Untreated Adult Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2010-05 | PHASE1 |
| NCT01843179 | WITHDRAWN | Acute Myeloid Leukemia |
Massachusetts General Hospital |
2014-01 | PHASE2 |
| NCT02983097 | TERMINATED | Diffuse Large B-cell Lymphoma (DLBCL); Follicular Lymphoma Grade III (FL III°); Mantle Cell Lymphoma (MCL), Blastoid Variant; Burkitt Lymphoma (BL); Aggressive Marginal Zone Lymphoma (MZL) |
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH |
2010-11 | PHASE1; PHASE2 |
| NCT00103285 | COMPLETED | Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2005-04-11 | PHASE3 |
| NCT00369317 | COMPLETED | Childhood Acute Basophilic Leukemia; Childhood Acute Eosinophilic Leukemia; Childhood Acute Erythroleukemia (M6); Childhood Acute Megakaryocytic Leukemia (M7); Childhood Acute Minimally Differentiated Myeloid Leukemia (M0); Childhood Acute Monoblastic Leukemia (M5a); Childhood Acute Monocytic Leukemia (M5b); Childhood Acute Myeloblastic Leukemia With Maturation (M2); Childhood Acute Myeloblastic Leukemia Without Maturation (M1); Childhood Acute Myelomonocytic Leukemia (M4); Childhood Myelodysplastic Syndromes; de Novo Myelodysplastic Syndromes; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes; Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies |
Children's Oncology Group |
2007-03 | PHASE3 |
| NCT01414231 | UNKNOWN | Acute Myeloid Leukaemia |
University of Leipzig |
2002-04 | PHASE3 |
| NCT01635296 | COMPLETED | Myelogenous Leukemia, Acute |
Hoffmann-La Roche |
2012-07 | PHASE1 |
| NCT00795756 | COMPLETED | Acute Lymphoblastic Leukemia |
Northern Italy Leukemia Group |
2008-01 | PHASE2; PHASE3 |
| NCT01700413 | COMPLETED | Di Novo Acute Myeloid Leukemia |
Grupo Cooperativo de Estudio y Tratamiento de las Leucemias Agudas y Mielodisplasias |
2012-10 | PHASE2 |
| NCT00372593 | COMPLETED | Leukemia |
Children's Oncology Group |
2006-08 | PHASE3 |
| NCT01238211 | COMPLETED | Acute Myeloid Leukemia; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11; Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11; Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1; Core Binding Factor Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Therapy-Related Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2010-12-14 | PHASE2 |
| NCT01607645 | TERMINATED | Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Myeloid Leukemia; Refractory Anemia With Excess Blasts |
Fred Hutchinson Cancer Center |
2012-07 | PHASE2 |
| NCT00671658 | COMPLETED | Leukemia; Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2002-11 | PHASE2 |
| NCT00992602 | COMPLETED | Central Nervous System Metastases; Leptomeningeal Metastases; Recurrent Breast Cancer; Stage IV Breast Cancer; Tumors Metastatic to Brain |
University of Washington |
2011-04 | PHASE2 |
| NCT01567059 | COMPLETED | Acute Myeloid Leukemia With Multilineage Dysplasia; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); de Novo Myelodysplastic Syndromes; Previously Treated Myelodysplastic Syndromes; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes; Untreated Adult Acute Myeloid Leukemia |
Fred Hutchinson Cancer Center |
2012-05 | PHASE2 |
| NCT01249430 | COMPLETED | Recurrent Adult Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2011-01-20 | PHASE1 |
| NCT01035502 | COMPLETED | Acute Myeloid Leukemia |
Clavis Pharma |
2009-12 | PHASE2 |
| NCT00410423 | COMPLETED | Relapsed Acute Leukemia; Refractory Acute Leukemia |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2006-01 | PHASE1; PHASE2 |
| NCT00647049 | UNKNOWN | Primary Non Hodgkin Lymphoma of the Central Nervous System |
University Hospital Freiburg |
2007-01 | PHASE2 |
| NCT01005914 | TERMINATED | Leukemia |
OHSU Knight Cancer Institute |
2009-06 | PHASE2 |
| NCT00945815 | COMPLETED | Leukemia |
SWOG Cancer Research Network |
2010-09 | PHASE2 |
| NCT01147939 | COMPLETED | Acute Myeloid Leukemia (AML) |
Clavis Pharma |
2010-06 | PHASE3 |
| NCT00583102 | TERMINATED | Acute Myeloid Leukemia |
University of Iowa |
2001-06 | PHASE1; PHASE2 |
| NCT01783964 | COMPLETED | Not Applicable as This is a Mass Balance/Pharmacokinetic Study Performed in Healthy Subjects |
Clavis Pharma |
2013-02 | PHASE1 |
| NCT00915252 | COMPLETED | Acute Myeloid Leukemia |
University Hospital Muenster |
2009-07 | PHASE2 |
| NCT00590837 | COMPLETED | Acute Myeloid Leukemia |
University Hospital, Bordeaux |
2008-02 | PHASE3 |
| NCT00838240 | UNKNOWN | Leukemia; Myelodysplastic Syndromes |
European Organisation for Research and Treatment of Cancer - EORTC |
2008-11 | PHASE1; PHASE2 |
| NCT00854867 | COMPLETED | Solid Tumour Neoplastic Meningitis; Brain Metastases |
Mundipharma Research Limited |
2011-02 | PHASE1 |
| NCT01031368 | COMPLETED | Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Acute Promyelocytic Leukemia (M3); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia; Untreated Adult Acute Myeloid Leukemia |
Nohla Therapeutics, Inc. |
2009-12 | PHASE1 |
| NCT00454480 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
The University of New South Wales |
2006-08 | PHASE2; PHASE3 |
| NCT01083342 | COMPLETED | CNS Lymphoma |
Samsung Medical Center |
2010-01 | PHASE2 |
| NCT00577629 | COMPLETED | Lymphoma, B-Cell |
Duke University |
2005-06-18 | PHASE2 |
| NCT00055874 | COMPLETED | Leukemia |
Heidelberg University |
2002-06 | PHASE3 |
| NCT00804856 | COMPLETED | Leukemia, Myeloid, Acute |
Boehringer Ingelheim |
2008-11-27 | PHASE2 |
| NCT00990054 | COMPLETED | Acute Myeloid Leukemia |
Genzyme, a Sanofi Company |
2009-12 | PHASE1 |
| NCT00333840 | COMPLETED | Chronic Myelogenous Leukemia |
Novartis Pharmaceuticals |
2000-06 | PHASE3 |
| NCT00073957 | COMPLETED | Lymphoma |
Beth Israel Deaconess Medical Center |
2003-12 | PHASE2 |
| NCT00430118 | COMPLETED | Leukemia |
University Hospital Schleswig-Holstein |
2000-07 | PHASE3 |
| NCT00357305 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Basophilic Leukemia; Adult Acute Eosinophilic Leukemia; Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Acute Promyelocytic Leukemia (M3); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Blastic Phase Chronic Myelogenous Leukemia; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Chronic Neutrophilic Leukemia; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Polycythemia Vera; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes |
National Cancer Institute (NCI) |
2006-05 | PHASE1 |
| NCT00054327 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Case Comprehensive Cancer Center |
2000-11 | PHASE2 |
| NCT00002766 | COMPLETED | Leukemia; Lymphoma |
Memorial Sloan Kettering Cancer Center |
1996-03 | PHASE3 |
| NCT00151242 | COMPLETED | Acute Myeloid Leukemia |
University of Ulm |
2004-07 | PHASE2; PHASE3 |
| NCT00268229 | COMPLETED | Leukemia |
The Cleveland Clinic |
2003-07 | PHASE1 |
| NCT00939653 | TERMINATED | Relapsed Acute Myelogenous Leukemia |
Therapeutic Advances in Childhood Leukemia Consortium |
2009-07-10 | PHASE2 |
| NCT00927498 | COMPLETED | Acute Myeloid Leukemia |
Acute Leukemia French Association |
2007-12 | PHASE3 |
| NCT00093600 | COMPLETED | Acute Myeloid Leukemia (AML) |
Novartis Pharmaceuticals |
2004-02 | PHASE1 |
| NCT00992134 | COMPLETED | Lymphoma, Mantle-Cell |
St. Bortolo Hospital |
2009-06 | PHASE2 |
| NCT00428558 | COMPLETED | Acute Myeloid Leukemia |
Assistance Publique - Hôpitaux de Paris |
2007-07 | PHASE3 |
| NCT00022490 | TERMINATED | Leukemia |
OHSU Knight Cancer Institute |
2001-06 | PHASE2 |
| NCT00774046 | COMPLETED | Myelodysplastic Syndrome; Acute Myeloid Leukemia |
University of Chicago |
2002-12 | PHASE2 |
| NCT00440726 | COMPLETED | Acute Lymphoblastic Leukemia |
Therapeutic Advances in Childhood Leukemia Consortium |
2006-08-04 | PHASE1; PHASE2 |
| NCT00863434 | TERMINATED | Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Recurrent Adult Acute Myeloid Leukemia |
University of Washington |
2009-02 | PHASE2 |
| NCT01018069 | TERMINATED | Leukemia |
Aegera Therapeutics |
2009-11 | PHASE2 |
| NCT00480987 | TERMINATED | Myelodysplastic Syndromes; Acute Myeloid Leukemia; Leukemia |
M.D. Anderson Cancer Center |
2007-07 | PHASE1; PHASE2 |
| NCT00503594 | UNKNOWN | Lymphoma |
Assistance Publique - Hôpitaux de Paris |
2007-07 | PHASE2 |
| NCT00928200 | TERMINATED | Relapsed Acute Lymphoblastic Leukemia; Allergy to PEG e.Coli Asparaginase; Allergy to Native e.Coli Asparaginase |
Therapeutic Advances in Childhood Leukemia Consortium |
2009-04-13 | PHASE1 |
| NCT00715637 | UNKNOWN | Secondary Acute Myeloid Leukemia (Secondary AML, sAML) |
Antisoma Research |
2007-06 | PHASE3 |
| NCT00788892 | COMPLETED | Acute Myeloid Leukemia |
Jazz Pharmaceuticals |
2008-10 | PHASE2 |
| NCT00609739 | TERMINATED | Leukemia |
Masonic Cancer Center, University of Minnesota |
1999-06 | PHASE1; PHASE2 |
| NCT00512252 | COMPLETED | Leukemia, Myeloid, Acute |
Washington University School of Medicine |
2007-07 | PHASE1; PHASE2 |
| NCT00003631 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1998-08 | PHASE2 |
| NCT00516828 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
NCIC Clinical Trials Group |
2007-11-27 | PHASE1; PHASE2 |
| NCT00354107 | TERMINATED | Anaplastic Large Cell Lymphoma; Recurrent Childhood Anaplastic Large Cell Lymphoma |
National Cancer Institute (NCI) |
2007-01 | PHASE1; PHASE2 |
| NCT00014495 | COMPLETED | Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Memorial Sloan Kettering Cancer Center |
2000-11 | PHASE1; PHASE2 |
| NCT00572065 | COMPLETED | Myelofibrosis |
Weill Medical College of Cornell University |
2008-02-29 | EARLY_PHASE1 |
| NCT00180102 | COMPLETED | Leukemia, Nonlymphocytic, Acute |
Technische Universität Dresden |
2003-12 | PHASE4 |
| NCT00057811 | COMPLETED | Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Untreated Childhood Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2004-06 | PHASE2 |
| NCT00780143 | TERMINATED | Relapsed/Refractory Leukemia |
PharmaMar |
2007-11 | PHASE1; PHASE2 |
| NCT00046930 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
Eastern Cooperative Oncology Group |
2002-09-17 | PHASE3 |
| NCT00523939 | TERMINATED | Neoplastic Meningitis; Lymphoma, B Cell |
Duke University |
2006-06 | PHASE2 |
| NCT00098423 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Basophilic Leukemia; Adult Acute Eosinophilic Leukemia; Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Blastic Phase Chronic Myelogenous Leukemia; Chronic Myelomonocytic Leukemia; de Novo Myelodysplastic Syndromes; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Refractory Anemia With Excess Blasts in Transformation; Relapsing Chronic Myelogenous Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes |
National Cancer Institute (NCI) |
2004-11 | PHASE1 |
| NCT00512083 | COMPLETED | Leukemia, Myeloid |
Antisoma Research |
2007-07 | PHASE2 |
| NCT00517699 | TERMINATED | Lymphoma |
Hoffmann-La Roche |
2007-09 | PHASE2 |
| NCT00270881 | COMPLETED | Acute Myelogenous Leukemia; Acute Lymphoblastic Leukemia; Chronic Myelogenous Leukemia; Myelodysplastic Syndrome |
Keio University |
2006-01 | PHASE1; PHASE2 |
| NCT00121303 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
Stichting Hemato-Oncologie voor Volwassenen Nederland |
2005-01 | PHASE3 |
| NCT00776373 | TERMINATED | ALL; Burkitt's Lymphoma; Lymphoblastic Leukemia; CML |
Abramson Cancer Center at Penn Medicine |
2007-01 | PHASE1; PHASE2 |
| NCT00618501 | COMPLETED | Leukemia |
Asan Medical Center |
2005-10 | PHASE2 |
| NCT00137995 | COMPLETED | Lymphoma, Large-Cell, Diffuse |
Lymphoma Study Association |
2003-06 | PHASE3 |
| NCT00176462 | COMPLETED | Acute Lymphocytic Leukemia |
Rutgers, The State University of New Jersey |
2001-02 | PHASE2 |
| NCT00136084 | COMPLETED | Leukemia, Myelocytic, Acute |
St. Jude Children's Research Hospital |
2002-08 | PHASE3 |
| NCT00003728 | UNKNOWN | Leukemia; Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-12 | PHASE3 |
| NCT00004128 | UNKNOWN | Leukemia |
European Organisation for Research and Treatment of Cancer - EORTC |
1999-09 | PHASE3 |
| NCT00061945 | COMPLETED | Acute Undifferentiated Leukemia; B-cell Adult Acute Lymphoblastic Leukemia; B-cell Childhood Acute Lymphoblastic Leukemia; L1 Adult Acute Lymphoblastic Leukemia; L1 Childhood Acute Lymphoblastic Leukemia; L2 Adult Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia; T-cell Adult Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2003-06 | PHASE1; PHASE2 |
| NCT00041132 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
2002-09 | PHASE2 |
| NCT00411281 | WITHDRAWN | Leukemia |
Children's Oncology Group |
2006-03 | PHASE3 |
| NCT00005945 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-06 | PHASE3 |
| NCT00210314 | COMPLETED | Lymphoma, B Cell |
International Extranodal Lymphoma Study Group (IELSG) |
2003-07 | PHASE2 |
| NCT00005585 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-04 | PHASE3 |
| NCT00085124 | COMPLETED | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Secondary Acute Myeloid Leukemia; Untreated Adult Acute Myeloid Leukemia |
National Cancer Institute (NCI) |
2003-12 | PHASE3 |
| NCT00274807 | COMPLETED | Leukemia |
The Cleveland Clinic |
2001-06 | PHASE2 |
| NCT00006343 | COMPLETED | Leukemia |
Novartis |
2000-06 | PHASE3 |
| NCT00058461 | TERMINATED | B-cell Childhood Acute Lymphoblastic Leukemia; Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; L3 Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma |
National Cancer Institute (NCI) |
2003-11 | PHASE2 |
| NCT00003593 | COMPLETED | Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Children's Oncology Group |
1999-06 | PHASE3 |
| NCT00002565 | COMPLETED | Lymphoma |
M.D. Anderson Cancer Center |
1994-05-25 | PHASE3 |
| NCT00334074 | COMPLETED | Acute Myelogenous Leukemia; Myelodysplastic Syndromes; Chronic Myelogenous Leukemia |
Baylor Research Institute |
2005-08 | PHASE2 |
| NCT00066794 | COMPLETED | Leukemia |
SWOG Cancer Research Network |
2004-07 | PHASE2 |
| NCT00020943 | COMPLETED | Lymphoma |
Alliance for Clinical Trials in Oncology |
2001-06 | PHASE2 |
| NCT00077116 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
European Organisation for Research and Treatment of Cancer - EORTC |
2003-11 | PHASE2 |
| NCT00002798 | COMPLETED | Childhood Acute Erythroleukemia (M6); Childhood Acute Megakaryocytic Leukemia (M7); Childhood Acute Monoblastic Leukemia (M5a); Childhood Acute Monocytic Leukemia (M5b); Childhood Acute Myeloblastic Leukemia With Maturation (M2); Childhood Acute Myeloblastic Leukemia Without Maturation (M1); Childhood Acute Myelomonocytic Leukemia (M4); Childhood Myelodysplastic Syndromes; Chronic Myelomonocytic Leukemia; de Novo Myelodysplastic Syndromes; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Excess Blasts in Transformation; Refractory Anemia With Ringed Sideroblasts; Secondary Myelodysplastic Syndromes; Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies |
National Cancer Institute (NCI) |
1996-08 | PHASE3 |
| NCT00004231 | COMPLETED | Lymphoma |
Northwestern University |
1999-10 | PHASE2 |
| NCT00049569 | COMPLETED | L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Non-T, Non-B Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2003-01 | |
| NCT01225874 | COMPLETED | Leukemia |
Children's Oncology Group |
1999-12 | |
| NCT00416819 | COMPLETED | Brain and Central Nervous System Tumors; Lymphoma |
University of California, San Francisco |
2003-09 | |
| NCT00002982 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1997-01 | PHASE2 |
| NCT00505700 | COMPLETED | Leukemia |
Massachusetts General Hospital |
2003-07 | PHASE1 |
| NCT00047021 | COMPLETED | Leukemia; Lymphoma |
Case Comprehensive Cancer Center |
2001-11 | PHASE2 |
| NCT00005596 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-04 | PHASE3 |
| NCT00003632 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1998-09 | PHASE2 |
| NCT00005802 | COMPLETED | Leukemia |
Fred Hutchinson Cancer Center |
1999-06 | PHASE1; PHASE2 |
| NCT00003187 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndromes |
Virginia Commonwealth University |
1995-05 | PHASE2; PHASE3 |
| NCT00002970 | COMPLETED | Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Lymphoblastic Lymphoma; T-cell Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
1997-06 | PHASE2 |
| NCT00017342 | COMPLETED | Leukemia |
Virginia Commonwealth University |
2001-07 | PHASE2 |
| NCT00023920 | TERMINATED | Blastic Phase Chronic Myelogenous Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive |
National Cancer Institute (NCI) |
2001-07 | PHASE2 |
| NCT00002598 | COMPLETED | Leukemia |
Memorial Sloan Kettering Cancer Center |
1994-06 | PHASE2 |
| NCT00187122 | COMPLETED | Lymphoblastic Lymphoma |
St. Jude Children's Research Hospital |
1993-03 | |
| NCT00002704 | COMPLETED | Leukemia |
National Cancer Institute (NCI) |
1996-01 | PHASE2 |
| NCT00003407 | WITHDRAWN | Drug/Agent Toxicity by Tissue/Organ; Leukemia; Myelodysplastic Syndromes; Neutropenia |
Rush University Medical Center |
2001-02-13 | PHASE2 |
| NCT00002700 | COMPLETED | Leukemia; Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1995-08 | PHASE3 |
| NCT00002494 | COMPLETED | Leukemia; Lymphoma |
Alliance for Clinical Trials in Oncology |
1992-05 | PHASE2 |
| NCT00002868 | COMPLETED | Leukemia |
Eastern Cooperative Oncology Group |
1997-11-20 | PHASE3 |
| NCT00002718 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Memorial Sloan Kettering Cancer Center |
1995-11 | PHASE2 |
| NCT00002657 | COMPLETED | Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm |
SWOG Cancer Research Network |
1995-05 | PHASE2 |
| NCT00199056 | COMPLETED | Adult Acute Lymphocytic Leukemia |
Goethe University |
1999-10 | PHASE4 |
| NCT00002757 | COMPLETED | Leukemia; Lymphoma |
Children's Oncology Group |
2001-06 | PHASE3 |
| NCT00037583 | COMPLETED | Acute Myeloid Leukemia |
Wyeth is now a wholly owned subsidiary of Pfizer |
PHASE2 | |
| NCT00023777 | COMPLETED | Leukemia |
SWOG Cancer Research Network |
2001-08 | PHASE2 |
| NCT00199095 | COMPLETED | Adult Acute Lymphocytic Leukemia |
Goethe University |
1997-02 | PHASE4 |
| NCT00037596 | COMPLETED | Acute Myeloid Leukemia |
Wyeth is now a wholly owned subsidiary of Pfizer |
2000-08 | PHASE2 |
| NCT00005998 | WITHDRAWN | Lymphoma |
Masonic Cancer Center, University of Minnesota |
2000-01 | PHASE2 |
| NCT00006747 | COMPLETED | Graft Versus Host Disease; Lymphoma |
Alliance for Clinical Trials in Oncology |
2000-11 | PHASE2 |
| NCT00002471 | COMPLETED | Leukemia; Lymphoma |
Memorial Sloan Kettering Cancer Center |
1990-02 | PHASE2 |
| NCT00002816 | COMPLETED | Leukemia |
Children's Oncology Group |
1996-12 | PHASE3 |
| NCT00003671 | COMPLETED | Leukemia |
Children's Oncology Group |
1998-12 | PHASE2 |
| NCT00004056 | COMPLETED | Leukemia |
Children's Oncology Group |
1999-10 | PHASE1 |
| NCT00187005 | TERMINATED | Acute Lymphoblastic Leukemia |
St. Jude Children's Research Hospital |
1998-07 | PHASE3 |
| NCT00003061 | COMPLETED | Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1997-07 | PHASE2 |
| NCT00007852 | COMPLETED | Lymphoma |
University of Nebraska |
2000-09-01 | PHASE2 |
| NCT00002665 | COMPLETED | Leukemia; Neutropenia; Thrombocytopenia |
SWOG Cancer Research Network |
1995-07 | PHASE2 |
| NCT00003239 | COMPLETED | Leukemia |
M.D. Anderson Cancer Center |
1998-03 | PHASE2 |
| NCT00002552 | COMPLETED | Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm |
Barbara Ann Karmanos Cancer Institute |
1993-10 | PHASE2 |
| NCT00003079 | COMPLETED | Leukemia; Lymphoma |
Virginia Commonwealth University |
1997-09 | PHASE1 |
| NCT00004217 | COMPLETED | Leukemia |
SWOG Cancer Research Network |
2000-02 | PHASE2 |
| NCT00002818 | COMPLETED | Drug/Agent Toxicity by Tissue/Organ; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm |
Virginia Commonwealth University |
1995-02 | PHASE1 |
| NCT00002618 | COMPLETED | Lymphoma |
Children's Oncology Group |
1994-12 | PHASE3 |
| NCT00004215 | COMPLETED | Anemia; Leukemia; Neutropenia; Thrombocytopenia |
Memorial Sloan Kettering Cancer Center |
1999-08 | PHASE2 |
| NCT00002691 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1995-08 | PHASE2 |
| NCT00003405 | WITHDRAWN | Leukemia |
Rush University Medical Center |
1998-04 | PHASE2 |
| NCT00199069 | COMPLETED | Adult Acute Lymphocytic Leukemia |
Goethe University |
1993-04 | PHASE4 |
| NCT00002531 | UNKNOWN | Leukemia |
Johann Wolfgang Goethe University Hospital |
1993-01 | PHASE2 |
| NCT00005823 | COMPLETED | Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Leukemia Research Fund |
1998-12 | PHASE3 |
| NCT00002701 | UNKNOWN | Leukemia |
European Organisation for Research and Treatment of Cancer - EORTC |
1995-10 | PHASE3 |
| NCT00488709 | COMPLETED | Acute Myeloid Leukemia |
PETHEMA Foundation |
2003-05 | PHASE4 |
| NCT00004086 | UNKNOWN | Leukemia; Lymphoma |
Garden State Cancer Center at the Center for Molecular Medicine and Immunology |
1997-06 | PHASE1 |
| NCT00039910 | COMPLETED | Non-Hodgkin Lymphoma; Hodgkin Disease; Thrombocytopenia |
Pfizer |
2000-07 | PHASE3 |
| NCT00018954 | COMPLETED | Leukemia; Lymphoma |
National Institutes of Health Clinical Center (CC) |
1992-10 | PHASE2 |
| NCT00002926 | UNKNOWN | Leukemia; Myelodysplastic Syndromes |
European Organisation for Research and Treatment of Cancer - EORTC |
1996-12 | PHASE3 |
| NCT00080925 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
National Institutes of Health Clinical Center (CC) |
2004-02 | PHASE1 |
| NCT00559221 | UNKNOWN | Acute Myeloid Leukemia |
Cooperative Study Group A for Hematology |
2004-12 | PHASE2 |
| NCT00025402 | UNKNOWN | Leukemia |
III. Medizinische Klinik Mannheim |
1997-07 | PHASE3 |
| NCT00003602 | UNKNOWN | Leukemia; Myelodysplastic Syndromes |
Riverside Haematology Group |
1998-03 | PHASE3 |
| NCT00006045 | UNKNOWN | Leukemia |
Facet Biotech |
2000-03 | PHASE3 |
| NCT00669812 | UNKNOWN | Lymphoma; Small Intestine Cancer |
Cancer Research UK |
2008-02 | PHASE2 |
| NCT00343369 | UNKNOWN | Leukemia |
Universitätsklinikum Hamburg-Eppendorf |
2003-01 | |
| NCT00199147 | UNKNOWN | Acute Myeloid Leukemia |
Johann Wolfgang Goethe University Hospital |
2000-01 | PHASE4 |
| NCT00003268 | COMPLETED | Drug/Agent Toxicity by Tissue/Organ; Leukemia |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
1998-01 | PHASE1 |
| NCT00187161 | COMPLETED | Non-Hodgkin Lymphoma; Acute Lymphoblastic Leukemia, Mature B-Cell |
St. Jude Children's Research Hospital |
1994-11 | PHASE2 |
| NCT01302106 | WITHDRAWN | Myelodysplastic Syndromes |
Fondazione Italiana Sindromi Mielodisplastiche-ETS |
PHASE2 | |
| NCT00016887 | UNKNOWN | Lymphoma |
German Low Grade Lymphoma Study Group |
2000-12 | PHASE3 |
| NCT00003578 | UNKNOWN | Lymphoma |
Lymphoma Trials Office |
1993-01 | PHASE3 |
| NCT00002869 | UNKNOWN | Leukemia |
Medical Research Council |
1995-04 | PHASE3 |
| NCT00002532 | UNKNOWN | Leukemia |
Hannover Medical School |
1993-01 | PHASE2 |
| NCT00556127 | COMPLETED | Diffuse Large B-Cell Lymphoma; POOR PROGNOSIS |
Gruppo Italiano Multiregionale per lo studio dei Linfomi e delle Leucemie |
2002-06 | PHASE2 |
| NCT00180115 | COMPLETED | Leukemia, Nonlymphoblastic, Acute |
Technische Universität Dresden |
1996-02 | PHASE4 |
| NCT00004643 | COMPLETED | Lupus Erythematosus, Systemic |
National Center for Research Resources (NCRR) |
1995-02 | PHASE2 |
| NCT00000658 | COMPLETED | Lymphoma, Non-Hodgkin; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00002481 | UNKNOWN | Lymphoma |
St. Luke's Medical Center |
1990-03 | PHASE2 |
| NCT00003073 | UNKNOWN | Brain and Central Nervous System Tumors; Leukemia; Lymphoma; Unspecified Childhood Solid Tumor, Protocol Specific |
Pacira Pharmaceuticals, Inc |
1997-02 | PHASE1 |
| NCT00734773 | WITHDRAWN | Brain and Central Nervous System Tumors; Lymphoma; Neurotoxicity |
Northwestern University |
2008-11 | EARLY_PHASE1 |
| NCT00002499 | UNKNOWN | Leukemia |
Grupo Argentino de Tratamiento de la Leucemia Aguda |
1990-01 | PHASE2; PHASE3 |
| NCT00002771 | UNKNOWN | Leukemia |
German CML Study Group |
1995-01 | PHASE3 |
| NCT00029523 | COMPLETED | Meningeal Neoplasms |
Pacira Pharmaceuticals, Inc |
2001-04 | PHASE4 |
(data from https://clinicaltrials.gov, updated on 2026-07-30)
Check the
Cytarabine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
- Cytarabine Mechanism of Action: BCL-2 Inhibition in Leukemia Stem Cells Research
- Cytarabine Working Concentration | Cell Culture | Treatment
- Cytarabine Solubility in DMSO
- Cytarabine Stock Solution
- Cytarabine Storage
- Cytarabine Stability
- Cytarabine Combination Database
- Cytarabine Molecular Weight
- Cytarabine SMILES
- Cytarabine CAS Number
- Cytarabine Chemical Structure (2D and 3D)
- Cytarabine IC50 for Cell-based and Cell-free Assays
- Cytarabine Sigma (C1768)? Try a better option.
- Cytarabine MedChemExpress (HY-13605)? Try a better option.
- Cytarabine Cayman (16069)? Try a better option.
- Cytarabine APExBIO (A8405)? Try a better option.
- Cytarabine SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.