CAS No. 147-94-4
Batch:
Purity:99.99
Chemical Structure
Check the
Cytarabine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one | |
|---|---|---|
| CAS Number | 147-94-4 | |
| Molecular Formula |
C9H13N3O5 |
|
| Molecular Weight (MW) | 243.22 | |
| SMILES | C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O | |
| InChIKey | UHDGCWIWMRVCDJ-CCXZUQQUSA-N |
Cytarabine is an antimetabolite agent and DNA synthesis inhibitor that targets DNA polymerase to block nucleic acid synthesis. By incorporating into DNA, it causes steric hindrance that halts replication fork progression specifically during the S phase of the cell cycle. This inhibition of DNA replication and repair leads to significant cell cycle arrest, ultimately inducing both autophagy and apoptosis. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
49 mg/mL
(201.46 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 49 mg/mL |
| Ethanol | Insoluble |
| DMSO |
48 mg/mL
(197.35 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 48 mg/mL |
| Ethanol | Insoluble |
| DMSO |
48 mg/mL
(197.35 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 48 mg/mL |
| Ethanol | Insoluble |
| DMSO |
49 mg/mL
(201.46 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 49 mg/mL |
| Ethanol | Insoluble |
| DMSO |
48 mg/mL
(197.35 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 48 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Cytarabine Mechanism of Action: BCL-2 Inhibition in Leukemia Stem Cells Research
- Cytarabine Clinical Trials
- Cytarabine Working Concentration | Cell Culture | Treatment
- Cytarabine Solubility in DMSO
- Cytarabine Stock Solution
- Cytarabine Storage
- Cytarabine Stability
- Cytarabine Combination Database
- Cytarabine Molecular Weight
- Cytarabine SMILES
- Cytarabine Chemical Structure (2D and 3D)
- Cytarabine IC50 for Cell-based and Cell-free Assays
- Cytarabine Sigma (C1768)? Try a better option.
- Cytarabine MedChemExpress (HY-13605)? Try a better option.
- Cytarabine Cayman (16069)? Try a better option.
- Cytarabine APExBIO (A8405)? Try a better option.
- Cytarabine SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.