CAS No. 6055-19-2
Batch:
Purity:99.20
Chemical Structure
Check the
Cyclophosphamide Monohydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | N,N-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine;hydrate | |
|---|---|---|
| CAS Number | 6055-19-2 | |
| Molecular Formula |
C7H15Cl2N2O2P.H2O |
|
| Molecular Weight (MW) | 279.1 | |
| SMILES | C1CNP(=O)(OC1)N(CCCl)CCCl.O | |
| InChIKey | PWOQRKCAHTVFLB-UHFFFAOYSA-N |
Biological Activity
Cyclophosphamide Monohydrate is a nitrogen mustard alkylating agent that targets genomic DNA by attaching alkyl groups to guanine bases. This alkylation leads to DNA crosslinking, strand breakage, and induction of mutations, ultimately inhibiting DNA replication and triggering cell death. Additionally, Cyclophosphamide Monohydrate is widely utilized to induce animal models of anemia and bone marrow suppression. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
55 mg/mL
(197.06 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 55 mg/mL |
| Ethanol | 55 mg/mL |
| DMSO |
56 mg/mL
(200.64 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 56 mg/mL |
| Ethanol | 56 mg/mL |
| DMSO |
56 mg/mL
(200.64 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 56 mg/mL |
| Ethanol | 56 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Reference
Jump to
- Cyclophosphamide Monohydrate Clinical Trials
- Cyclophosphamide Monohydrate Solubility in DMSO
- Cyclophosphamide Monohydrate Stock Solution
- Cyclophosphamide Monohydrate Storage
- Cyclophosphamide Monohydrate Stability
- Cyclophosphamide Monohydrate Molecular Weight
- Cyclophosphamide Monohydrate SMILES
- Cyclophosphamide Monohydrate Chemical Structure (2D and 3D)
- Cyclophosphamide Monohydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.