CAS No. 6202-23-9

Batch: Purity:99.89
Cyclobenzaprine HCl Chemical Structure
Chemical Structure
Check the Cyclobenzaprine HCl product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 6202-23-9
Molecular Formula

C20H22ClN

Molecular Weight (MW) 311.85
SMILES CN(C)CCC=C1C2=CC=CC=C2C=CC3=CC=CC=C31.Cl

Ordering Information

Biological Activity

Cyclobenzaprine HCl is a centrally acting muscle relaxant that functions as an antagonist at 5-HT2 receptors. By targeting 5-HT2 receptors within the central nervous system, it inhibits serotonergic transmission and modulates spinal interneuron signaling pathways. This receptor blockade effectively suppresses polysynaptic spinal reflex activity, leading to reduced skeletal muscle hypertonia and significant attenuation of involuntary muscle spasms.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 62 mg/mL (198.81 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 62 mg/mL
Ethanol 62 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.