Numerous clinical trials evaluate therapeutic interventions across diverse medical conditions, including acute lymphoblastic leukemia, non-Hodgkin lymphoma, breast carcinoma, ovarian cancer, and glaucoma. Spanning Early Phase 1 through Phase 4 studies, these evaluations reflect a progression from preliminary safety trials to large-scale comparative analyses. Sponsored by prominent organizations such as the National Cancer Institute, Children's Oncology Group, Mayo Clinic, and City of Hope Medical Center, the trials encompass various operational statuses, including actively recruiting, completed, active not recruiting, and terminated studies.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT04539366 | SUSPENDED | Recurrent Childhood Neuroblastoma; Recurrent Childhood Osteosarcoma; Recurrent Neuroblastoma; Recurrent Osteosarcoma; Refractory Childhood Neuroblastoma; Refractory Childhood Osteosarcoma; Refractory Neuroblastoma; Refractory Osteosarcoma |
National Cancer Institute (NCI) |
2022-01-25 | PHASE1 |
| NCT06191887 | RECRUITING | B-Cell Non-Hodgkin Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Diffuse Large B-Cell Lymphoma; Refractory Follicular Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Marginal Zone Lymphoma; Refractory Small Lymphocytic Lymphoma; Refractory Transformed Chronic Lymphocytic Leukemia |
Mayo Clinic |
2024-03-18 | PHASE1 |
| NCT07220187 | NOT_YET_RECRUITING | Richter Syndrome; Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma; Transformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma |
SWOG Cancer Research Network |
2026-08-31 | PHASE3 |
| NCT07072585 | NOT_YET_RECRUITING | Stage II T Lymphoblastic Leukemia/Lymphoma; Stage III T Lymphoblastic Leukemia/Lymphoma; Stage IV T Lymphoblastic Leukemia/Lymphoma; T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
Children's Oncology Group |
2026-08-28 | PHASE2; PHASE3 |
| NCT07724457 | NOT_YET_RECRUITING | Recurrent Burkitt Lymphoma; Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements; Refractory Burkitt Lymphoma; Refractory High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements |
National Cancer Institute (NCI) |
2026-10-30 | PHASE2; PHASE3 |
| NCT05929768 | RECRUITING | Anatomic Stage I Breast Cancer AJCC v8; Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage IIIA Breast Cancer AJCC v8; Anatomic Stage IIIB Breast Cancer AJCC v8; Early Stage Triple-Negative Breast Carcinoma |
SWOG Cancer Research Network |
2023-09-15 | PHASE3 |
| NCT06058377 | RECRUITING | Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage III Breast Cancer AJCC v8; HER2-Negative Breast Carcinoma; Hormone Receptor-Positive Breast Carcinoma |
National Cancer Institute (NCI) |
2023-11-27 | PHASE3 |
| NCT05031897 | RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Adult T-Cell Leukemia/Lymphoma; Aplastic Anemia; Chronic Lymphocytic Leukemia; Chronic Myeloid Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Essential Thrombocythemia; Hematopoietic and Lymphatic System Neoplasm; Hodgkin Lymphoma; Multiple Myeloma; Myelodysplastic Syndrome; Myelofibrosis; Myeloid Neoplasm; Non-Hodgkin Lymphoma; Polycythemia Vera; Small Lymphocytic Lymphoma |
Thomas Jefferson University |
2021-10-25 | PHASE2 |
| NCT03959085 | RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Central Nervous System Leukemia; Mixed Phenotype Acute Leukemia; Testicular Leukemia |
Children's Oncology Group |
2019-10-31 | PHASE3 |
| NCT06013423 | RECRUITING | Acute Leukemia of Ambiguous Lineage; Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Blastic Plasmacytoid Dendritic Cell Neoplasm; Hematopoietic and Lymphatic System Neoplasm; Mixed Phenotype Acute Leukemia; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Non-Hodgkin Lymphoma; Chronic Myeloid Leukemia, BCR-ABL1 Positive |
Fred Hutchinson Cancer Center |
2024-07-23 | PHASE2 |
| NCT06940297 | RECRUITING | Recurrent Multiple Myeloma; Refractory Multiple Myeloma |
Mayo Clinic |
2025-09-18 | PHASE2 |
| NCT07662928 | NOT_YET_RECRUITING | Adult Burkitt Lymphoma |
AIDS Malignancy Consortium |
2026-09-17 | PHASE2 |
| NCT05675410 | RECRUITING | Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 |
National Cancer Institute (NCI) |
2023-05-11 | PHASE3 |
| NCT07636564 | NOT_YET_RECRUITING | Acute Leukemia of Ambiguous Lineage; B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; T Acute Lymphoblastic Leukemia |
SWOG Cancer Research Network |
2026-10-14 | PHASE2 |
| NCT07466316 | RECRUITING | Rhabdomyosarcoma |
Children's Oncology Group |
2026-07-14 | PHASE3 |
| NCT06401330 | RECRUITING | Stage I Mixed Cell Type Kidney Wilms Tumor; Stage II Mixed Cell Type Kidney Wilms Tumor; Stage III Mixed Cell Type Kidney Wilms Tumor; Stage IV Mixed Cell Type Kidney Wilms Tumor |
Children's Oncology Group |
2025-04-15 | PHASE3 |
| NCT06124157 | RECRUITING | B Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2025-05-30 | PHASE2 |
| NCT07803653 | NOT_YET_RECRUITING | Metastatic Castration-Resistant Prostate Adenocarcinoma; Stage IVB Prostate Cancer AJCC v8 |
Fred Hutchinson Cancer Center |
2026-10-31 | PHASE1 |
| NCT07714421 | NOT_YET_RECRUITING | Diffuse Large B-Cell Lymphoma; Grade 3b Follicular Lymphoma; High Grade B-Cell Lymphoma; Primary Mediastinal Large B-Cell Lymphoma; Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma |
Jonsson Comprehensive Cancer Center |
2026-12-08 | PHASE1 |
| NCT03126916 | RECRUITING | Ganglioneuroblastoma; Ganglioneuroblastoma, Nodular; Neuroblastoma |
Children's Oncology Group |
2018-05-14 | PHASE3 |
| NCT07228624 | RECRUITING | Myelodysplastic/Myeloproliferative Neoplasm; Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2026-02-04 | PHASE2 |
| NCT06022939 | RECRUITING | AL Amyloidosis |
SWOG Cancer Research Network |
2024-07-01 | PHASE3 |
| NCT05304585 | RECRUITING | Embryonal Rhabdomyosarcoma; Fusion-Negative Alveolar Rhabdomyosarcoma; Spindle Cell/Sclerosing Rhabdomyosarcoma |
Children's Oncology Group |
2022-08-04 | PHASE3 |
| NCT05633615 | RECRUITING | Diffuse Large B-Cell Lymphoma; Grade 3b Follicular Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Transformed Follic Lymph to Diff Large B-Cell Lymphoma; Transformed Marg Zone Lymph to Diff Large B-Cell Lymphoma |
SWOG Cancer Research Network |
2023-06-12 | PHASE2 |
| NCT07097363 | RECRUITING | B-Cell Non-Hodgkin Lymphoma; Burkitt Lymphoma; Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements; High Grade B-Cell Lymphoma, Not Otherwise Specified; Primary Mediastinal Large B-Cell Lymphoma; T-Cell/Histiocyte-Rich Large B-Cell Lymphoma; Transformed B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma to Diffuse Large B-Ce |
University of Washington |
2025-12-07 | PHASE2 |
| NCT06042569 | RECRUITING | Anatomic Stage I Breast Cancer AJCC v8; Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage III Breast Cancer AJCC v8; HER2-Negative Breast Carcinoma |
City of Hope Medical Center |
2024-09-16 | PHASE2 |
| NCT05382338 | RECRUITING | Childhood Medulloblastoma |
Children's Oncology Group |
2023-02-20 | PHASE3 |
| NCT06172296 | RECRUITING | Ganglioneuroblastoma, Nodular; Neuroblastoma |
National Cancer Institute (NCI) |
2024-04-19 | PHASE3 |
| NCT07437963 | NOT_YET_RECRUITING | Recurrent Ganglioneuroblastoma; Recurrent Neuroblastoma; Refractory Ganglioneuroblastoma; Refractory Neuroblastoma |
National Cancer Institute (NCI) |
2026-10-28 | PHASE1; PHASE2 |
| NCT04139304 | RECRUITING | Plasmablastic Lymphoma; Ann Arbor Stage I Diffuse Large B-Cell Lymphoma; Ann Arbor Stage II Diffuse Large B-Cell Lymphoma; Ann Arbor Stage III Diffuse Large B-Cell Lymphoma; Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma |
AIDS Malignancy Consortium |
2021-05-24 | EARLY_PHASE1 |
| NCT06647953 | RECRUITING | Pleuropulmonary Blastoma |
Children's Oncology Group |
2025-03-21 | PHASE3 |
| NCT06918431 | RECRUITING | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; Lymphoblastic Lymphoma |
City of Hope Medical Center |
2025-10-10 | PHASE2 |
| NCT03017820 | RECRUITING | B-Cell Non-Hodgkin Lymphoma; Histiocytic and Dendritic Cell Neoplasm; Myelodysplastic Syndrome; Previously Treated Myelodysplastic Syndrome; Recurrent Adult Acute Myeloid Leukemia; Recurrent Anaplastic Large Cell Lymphoma; Recurrent Angioimmunoblastic T-Cell Lymphoma; Recurrent Mycosis Fungoides; Recurrent Plasma Cell Myeloma; Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma; Recurrent T-Cell Non-Hodgkin Lymphoma; Refractory Acute Myeloid Leukemia; Refractory Anaplastic Large Cell Lymphoma; Refractory Angioimmunoblastic T-Cell Lymphoma; Refractory Mycosis Fungoides; Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified; Refractory Plasma Cell Myeloma; Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma; Refractory T-Cell Non-Hodgkin Lymphoma |
Mayo Clinic |
2017-04-04 | PHASE1 |
| NCT06317662 | RECRUITING | Acute Leukemia of Ambiguous Lineage; B Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2025-06-05 | PHASE2 |
| NCT04579523 | NOT_YET_RECRUITING | Multiple Myeloma; Recurrent Multiple Myeloma; Refractory Multiple Myeloma |
Fred Hutchinson Cancer Center |
2027-06-01 | PHASE1 |
| NCT05225363 | RECRUITING | Platinum-Resistant Ovarian Carcinoma |
City of Hope Medical Center |
2023-05-01 | PHASE1 |
| NCT06815003 | RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Chronic Myelomonocytic Leukemia; Graft Versus Host Disease; Myelodysplastic Syndrome; Myeloproliferative Neoplasm |
City of Hope Medical Center |
2025-04-18 | PHASE2 |
| NCT06483048 | RECRUITING | Platinum-Resistant Fallopian Tube Carcinoma; Platinum-Resistant Ovarian Carcinoma; Platinum-Resistant Primary Peritoneal Carcinoma; Recurrent Fallopian Tube Carcinoma; Recurrent Fallopian Tube Carcinosarcoma; Recurrent Female Reproductive System Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Ovarian Carcinosarcoma; Recurrent Platinum-Resistant Fallopian Tube Carcinoma; Recurrent Platinum-Resistant Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Recurrent Primary Peritoneal Carcinosarcoma; Refractory Fallopian Tube Carcinoma; Refractory Female Reproductive System Carcinoma; Refractory Ovarian Carcinoma; Refractory Primary Peritoneal Carcinoma |
Mayo Clinic |
2024-09-20 | PHASE1 |
| NCT07016399 | RECRUITING | Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage IIIA Breast Cancer AJCC v8; Triple-Negative Breast Carcinoma |
Vandana Abramson |
2025-09-09 | PHASE2 |
| NCT02861417 | ACTIVE_NOT_RECRUITING | Hematopoietic and Lymphoid Cell Neoplasm; High Risk Acute Myeloid Leukemia; High Risk Myelodysplastic Syndrome; Lymphoproliferative Disorder; Myelodysplastic Syndrome; Myelodysplastic/Myeloproliferative Neoplasm; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Recurrent High Risk Myelodysplastic Syndrome; Recurrent Hodgkin Lymphoma; Recurrent Myelodysplastic Syndrome; Recurrent Non-Hodgkin Lymphoma; Recurrent Plasma Cell Myeloma |
M.D. Anderson Cancer Center |
2016-08-05 | PHASE2 |
| NCT07224100 | RECRUITING | B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; B Lymphoblastic Leukemia/Lymphoma With t(9;22)(q34.1;q11.2); BCR-ABL1; Lymphoblastic Lymphoma |
University of Washington |
2026-03-30 | PHASE2 |
| NCT07758673 | NOT_YET_RECRUITING | Recurrent B Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory B Lymphoblastic Lymphoma |
City of Hope Medical Center |
2027-04-17 | PHASE1 |
| NCT04530565 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 |
National Cancer Institute (NCI) |
2021-01-25 | PHASE3 |
| NCT07133997 | RECRUITING | Recurrent B Acute Lymphoblastic Leukemia; Refractory B Acute Lymphoblastic Leukemia |
City of Hope Medical Center |
2026-05-20 | PHASE1 |
| NCT07349771 | WITHDRAWN | Hematopoietic and Lymphatic System Neoplasm |
Mayo Clinic |
2026-06-01 | PHASE2 |
| NCT06968195 | SUSPENDED | Advanced Hepatocellular Carcinoma; Metastatic Hepatocellular Carcinoma; Recurrent Hepatocellular Carcinoma; Refractory Hepatocellular Carcinoma; Stage III Hepatocellular Carcinoma AJCC v8; Stage IV Hepatocellular Carcinoma AJCC v8 |
Roswell Park Cancer Institute |
2026-07-15 | PHASE1 |
| NCT05625594 | RECRUITING | Central Nervous System Lymphoma |
City of Hope Medical Center |
2023-06-29 | PHASE1 |
| NCT07649304 | NOT_YET_RECRUITING | AIDS-Related Diffuse Large B-cell Lymphoma; Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements; High Grade B-Cell Lymphoma, Not Otherwise Specified; Lugano Classification Stage II Adult Non-Hodgkin Lymphoma AJCC v8; Lugano Classification Stage III Adult Non-Hodgkin Lymphoma AJCC v8; Lugano Classification Stage IV Adult Non-Hodgkin Lymphoma AJCC v8; Plasmablastic Lymphoma; Primary Effusion Lymphoma |
National Cancer Institute (NCI) |
2026-10-09 | PHASE1 |
| NCT06871410 | RECRUITING | Recurrent Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia |
Roswell Park Cancer Institute |
2026-02-02 | PHASE1 |
| NCT03984448 | ACTIVE_NOT_RECRUITING | Diffuse Large B-Cell Lymphoma; Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Double-Expressor Lymphoma; EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; High Grade B-Cell Lymphoma, Not Otherwise Specified; Neoplastic Cells With Double Expression of MYC and BCL2 Proteins Present; Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma |
National Cancer Institute (NCI) |
2019-10-22 | PHASE2; PHASE3 |
| NCT02629809 | ACTIVE_NOT_RECRUITING | Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma |
M.D. Anderson Cancer Center |
2016-03-18 | PHASE2 |
| NCT02724579 | ACTIVE_NOT_RECRUITING | Medulloblastoma |
Children's Oncology Group |
2017-11-17 | PHASE2 |
| NCT05269381 | RECRUITING | Anatomic Stage III Breast Cancer AJCC v8; Anatomic Stage IIIA Breast Cancer AJCC v8; Anatomic Stage IIIB Breast Cancer AJCC v8; Anatomic Stage IIIC Breast Cancer AJCC v8; Anatomic Stage IV Breast Cancer AJCC v8; Clinical Stage III Cutaneous Melanoma AJCC v8; Clinical Stage III Gastric Cancer AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Merkel Cell Carcinoma AJCC v8; Clinical Stage IV Cutaneous Melanoma AJCC v8; Clinical Stage IV Gastric Cancer AJCC v8; Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IV Merkel Cell Carcinoma AJCC v8; Clinical Stage IVA Gastric Cancer AJCC v8; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVB Gastric Cancer AJCC v8; Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8; Locally Advanced Cervical Carcinoma; Locally Advanced Endometrial Carcinoma; Locally Advanced Gastric Adenocarcinoma; Locally Advanced Gastroesophageal Junction Adenocarcinoma; Locally Advanced Head and Neck Squamous Cell Carcinoma; Locally Advanced Hepatocellular Carcinoma; Locally Advanced Lung Non-Small Cell Carcinoma; Locally Advanced Malignant Solid Neoplasm; Locally Advanced Melanoma; Locally Advanced Merkel Cell Carcinoma; Locally Advanced Renal Cell Carcinoma; Locally Advanced Skin Squamous Cell Carcinoma; Locally Advanced Triple-Negative Breast Carcinoma; Locally Advanced Unresectable Breast Carcinoma; Locally Advanced Unresectable Cervical Carcinoma; Locally Advanced Unresectable Gastric Adenocarcinoma; Locally Advanced Unresectable Gastroesophageal Junction Adenocarcinoma; Locally Advanced Unresectable Renal Cell Carcinoma; Locally Advanced Urothelial Carcinoma; Metastatic Cervical Carcinoma; Metastatic Endometrial Carcinoma; Metastatic Gastric Adenocarcinoma; Metastatic Gastroesophageal Junction Adenocarcinoma; Metastatic Head and Neck Squamous Cell Carcinoma; Metastatic Hepatocellular Carcinoma; Metastatic Lung Non-Small Cell Carcinoma; Metastatic Malignant Solid Neoplasm; Metastatic Melanoma; Metastatic Merkel Cell Carcinoma; Metastatic Renal Cell Carcinoma; Metastatic Skin Squamous Cell Carcinoma; Metastatic Triple-Negative Breast Carcinoma; Metastatic Urothelial Carcinoma; Skin Squamous Cell Carcinoma; Stage III Cervical Cancer AJCC v8; Stage III Hepatocellular Carcinoma AJCC v8; Stage III Lung Cancer AJCC v8; Stage III Renal Cell Cancer AJCC v8; Stage IIIA Cervical Cancer AJCC v8; Stage IIIA Hepatocellular Carcinoma AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIA Uterine Corpus Cancer AJCC v8; Stage IIIB Cervical Cancer AJCC v8; Stage IIIB Hepatocellular Carcinoma AJCC v8; Stage IIIB Lung Cancer AJCC v8; Stage IIIB Uterine Corpus Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IIIC Uterine Corpus Cancer AJCC v8; Stage IIIC1 Uterine Corpus Cancer AJCC v8; Stage IIIC2 Uterine Corpus Cancer AJCC v8; Stage IV Cervical Cancer AJCC v8; Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage IV Hepatocellular Carcinoma AJCC v8; Stage IV Lung Cancer AJCC v8; Stage IV Renal Cell Cancer AJCC v8; Stage IVA Cervical Cancer AJCC v8; Stage IVA Hepatocellular Carcinoma AJCC v8; Stage IVA Lung Cancer AJCC v8; Stage IVA Uterine Corpus Cancer AJCC v8; Stage IVB Cervical Cancer AJCC v8; Stage IVB Hepatocellular Carcinoma AJCC v8; Stage IVB Lung Cancer AJCC v8; Stage IVB Uterine Corpus Cancer AJCC v8; Triple-Negative Breast Carcinoma; Unresectable Cervical Carcinoma; Unresectable Endometrial Carcinoma; Unresectable Gastric Adenocarcinoma; Unresectable Gastroesophageal Junction Adenocarcinoma; Unresectable Head and Neck Squamous Cell Carcinoma; Unresectable Hepatocellular Carcinoma; Unresectable Lung Non-Small Cell Carcinoma; Unresectable Malignant Solid Neoplasm; Unresectable Melanoma; Unresectable Merkel Cell Carcinoma; Unresectable Renal Cell Carcinoma; Unresectable Skin Squamous Cell Carcinoma; Unresectable Triple-Negative Breast Carcinoma; Unresectable Urothelial Carcinoma; Breast Adenocarcinoma; Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8; Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8; Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8; Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8; Invasive Breast Lobular Carcinoma |
Mayo Clinic |
2022-03-31 | PHASE1; PHASE2 |
| NCT04892277 | RECRUITING | Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Small Lymphocytic Lymphoma; Refractory Transformed Chronic Lymphocytic Leukemia |
Mayo Clinic |
2022-10-03 | PHASE1 |
| NCT06094842 | WITHDRAWN | Prostate Carcinoma; Prostate Small Cell Neuroendocrine Carcinoma; Stage III Prostate Cancer AJCC v8; Stage IV Prostate Cancer AJCC v8 |
Fred Hutchinson Cancer Center |
2025-04-15 | PHASE1 |
| NCT06738368 | RECRUITING | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; T Acute Lymphoblastic Leukemia |
University of Washington |
2026-05-08 | PHASE2 |
| NCT05077527 | RECRUITING | AIDS-Related Diffuse Large B-cell Lymphoma; AIDS-Related Non-Hodgkin Lymphoma; HIV Infection; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Grade 3b Follicular Lymphoma; Recurrent High Grade B-Cell Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Recurrent Transformed B-Cell Non-Hodgkin Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Grade 3b Follicular Lymphoma; Refractory High Grade B-Cell Lymphoma; Refractory Non-Hodgkin Lymphoma; Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Refractory Transformed B-Cell Non-Hodgkin Lymphoma |
AIDS Malignancy Consortium |
2025-02-13 | PHASE1 |
| NCT06043713 | RECRUITING | Metastatic Malignant Solid Neoplasm |
Fred Hutchinson Cancer Center |
2023-12-15 | PHASE1 |
| NCT03247088 | ACTIVE_NOT_RECRUITING | Recurrent Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2017-07-30 | PHASE1; PHASE2 |
| NCT07676877 | NOT_YET_RECRUITING | Recurrent Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma |
Nathan Denlinger |
2026-09-01 | PHASE1 |
| NCT07548983 | RECRUITING | Acute Myeloid Leukemia |
OHSU Knight Cancer Institute |
2026-04-21 | PHASE1 |
| NCT05989828 | RECRUITING | Triple Negative Breast Cancer |
University of Southern California |
2024-12-17 | PHASE1 |
| NCT07647068 | NOT_YET_RECRUITING | Locally Advanced Gastrointestinal Stromal Tumor; Metastatic Gastrointestinal Stromal Tumor; Recurrent Gastrointestinal Stromal Tumor; Refractory Malignant Gastrointestinal Stromal Tumor; Unresectable Malignant Gastrointestinal Stromal Tumor |
Joal Beane |
2026-08-15 | PHASE2 |
| NCT03622788 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Aplastic Anemia; Bone Marrow Failure; Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Follicular Lymphoma; Hodgkin Lymphoma; Mantle Cell Lymphoma; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Non-Hodgkin Lymphoma; Plasma Cell Myeloma |
M.D. Anderson Cancer Center |
2019-08-08 | PHASE1; PHASE2 |
| NCT07381556 | RECRUITING | Alopecia Areata(AA); Alopecia Areata (AA); Alopecia Totalis/Universalis; Alopecia Universalis (AU); Alopecia Totalis (AT); Alopecia Areata (& Ophiasis) |
Erasmus Medical Center |
2025-11-01 | PHASE4 |
| NCT01424982 | ACTIVE_NOT_RECRUITING | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Lymphoblastic Leukemia; Adult Acute Lymphoblastic Leukemia in Complete Remission; B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Philadelphia Chromosome Positive; Untreated Adult Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2011-10-05 | PHASE2 |
| NCT02389309 | ACTIVE_NOT_RECRUITING | Advanced Malignant Solid Neoplasm; Recurrent Brain Neoplasm; Recurrent Malignant Solid Neoplasm; Refractory Brain Neoplasm |
M.D. Anderson Cancer Center |
2015-10-05 | PHASE1 |
| NCT06626256 | WITHDRAWN | Locally Advanced Cervical Carcinoma; Locally Advanced Colorectal Carcinoma; Locally Advanced Malignant Solid Neoplasm; Locally Advanced Melanoma; Locally Advanced Pancreatic Ductal Adenocarcinoma; Locally Advanced Renal Cell Carcinoma; Metastatic Cervical Carcinoma; Metastatic Colorectal Carcinoma; Metastatic Malignant Solid Neoplasm; Metastatic Melanoma; Metastatic Pancreatic Ductal Adenocarcinoma; Metastatic Renal Cell Carcinoma; Stage II Pancreatic Cancer AJCC v8; Stage III Cervical Cancer AJCC v8; Stage III Colorectal Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage III Renal Cell Cancer AJCC v8; Stage IV Cervical Cancer AJCC v8; Stage IV Colorectal Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Stage IV Renal Cell Cancer AJCC v8; Unresectable Cervical Carcinoma; Unresectable Colorectal Carcinoma; Unresectable Malignant Solid Neoplasm; Unresectable Melanoma; Unresectable Pancreatic Ductal Adenocarcinoma; Unresectable Renal Cell Carcinoma |
City of Hope Medical Center |
2025-12-05 | PHASE1 |
| NCT01955460 | ACTIVE_NOT_RECRUITING | Metastatic Melanoma; Stage III Cutaneous Melanoma AJCC v7; Stage IIIA Cutaneous Melanoma AJCC v7; Stage IIIB Cutaneous Melanoma AJCC v7; Stage IIIC Cutaneous Melanoma AJCC v7; Stage IV Cutaneous Melanoma AJCC v6 and v7 |
M.D. Anderson Cancer Center |
2014-10-15 | PHASE1 |
| NCT06609928 | RECRUITING | Recurrent Childhood Acute Myeloid Leukemia; Refractory Childhood Acute Myeloid Leukemia |
Fred Hutchinson Cancer Center |
2025-02-24 | PHASE1 |
| NCT03914625 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Down Syndrome |
National Cancer Institute (NCI) |
2019-07-03 | PHASE3 |
| NCT07444710 | NOT_YET_RECRUITING | Ann Arbor Stage II Mantle Cell Lymphoma; Ann Arbor Stage III Mantle Cell Lymphoma; Ann Arbor Stage IV Mantle Cell Lymphoma |
National Cancer Institute (NCI) |
2026-10-30 | PHASE1 |
| NCT05411497 | ACTIVE_NOT_RECRUITING | Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
Mayo Clinic |
2022-06-20 | PHASE1 |
| NCT04745949 | RECRUITING | Ann Arbor Stage I Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Ann Arbor Stage II Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Ann Arbor Stage III Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Ann Arbor Stage IV Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
M.D. Anderson Cancer Center |
2021-05-10 | PHASE2 |
| NCT04007029 | ACTIVE_NOT_RECRUITING | CD19 Positive; CD20 Positive; Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Diffuse Large B-Cell Lymphoma; Refractory Follicular Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Refractory Small Lymphocytic Lymphoma |
Jonsson Comprehensive Cancer Center |
2019-10-04 | PHASE1 |
| NCT03136146 | RECRUITING | Recurrent Acute Lymphoblastic Leukemia; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Burkitt Leukemia; Recurrent Burkitt Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; Refractory Acute Lymphoblastic Leukemia; Refractory Burkitt Leukemia; Refractory Burkitt Lymphoma; Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; Refractory Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2017-08-09 | PHASE2 |
| NCT04022239 | RECRUITING | Hematopoietic and Lymphoid System Neoplasm |
M.D. Anderson Cancer Center |
2020-03-13 | PHASE1; PHASE2 |
| NCT04322318 | RECRUITING | Anaplastic Kidney Wilms Tumor; Recurrent Kidney Wilms Tumor; Stage II Kidney Wilms Tumor; Stage III Kidney Wilms Tumor; Stage IV Kidney Wilms Tumor |
Children's Oncology Group |
2020-10-19 | PHASE2 |
| NCT05418088 | RECRUITING | Recurrent Acute Lymphoblastic Leukemia; Recurrent B Acute Lymphoblastic Leukemia; Recurrent B-Cell Prolymphocytic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent High Grade B-Cell Lymphoma; Recurrent Indolent Non-Hodgkin Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory Acute Lymphoblastic Leukemia; Refractory B Acute Lymphoblastic Leukemia; Refractory B-Cell Prolymphocytic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory High Grade B-Cell Lymphoma; Refractory Indolent Non-Hodgkin Lymphoma; Refractory Non-Hodgkin Lymphoma; Refractory Transformed Chronic Lymphocytic Leukemia; Refactory Childhood Acute Lymphoblastic Leukemia; Refractory Childhood Non-Hodgkin Lymphoma |
Sumithira Vasu |
2022-06-30 | PHASE1 |
| NCT04301076 | RECRUITING | Acute Adult T-Cell Leukemia/Lymphoma; Adult T-Cell Leukemia/Lymphoma; Chronic Adult T-Cell Leukemia/Lymphoma; HTLV-1 Infection |
National Cancer Institute (NCI) |
2021-08-31 | PHASE1 |
| NCT02427620 | ACTIVE_NOT_RECRUITING | Blastoid Variant Mantle Cell Lymphoma; Mantle Cell Lymphoma; Pleomorphic Variant Mantle Cell Lymphoma |
M.D. Anderson Cancer Center |
2015-06-03 | PHASE2 |
| NCT05757310 | RECRUITING | Recurrent Severe Aplastic Anemia; Refractory Severe Aplastic Anemia |
City of Hope Medical Center |
2024-11-15 | PHASE1 |
| NCT05334329 | ACTIVE_NOT_RECRUITING | Advanced Lung Non-Small Cell Carcinoma; Metastatic Lung Non-Small Cell Carcinoma; Recurrent Lung Non-Small Cell Carcinoma; Refractory Lung Non-Small Cell Carcinoma; Stage III Lung Cancer AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIB Lung Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8; Stage IVA Lung Cancer AJCC v8; Stage IVB Lung Cancer AJCC v8 |
University of California, Irvine |
2022-07-20 | PHASE1 |
| NCT02727803 | RECRUITING | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Biphenotypic Leukemia; Acute Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia With Myelodysplasia-Related Changes; Acute Myeloid Leukemia With Variant MLL Translocations; B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Chemotherapy-Related Leukemia; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; ISS Stage II Plasma Cell Myeloma; ISS Stage III Plasma Cell Myeloma; Myelodysplastic Syndrome; Myelodysplastic Syndrome With Excess Blasts; Myelodysplastic Syndrome With Gene Mutation; Myelodysplastic/Myeloproliferative Neoplasm; Previously Treated Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Hodgkin Lymphoma; Recurrent Non-Hodgkin Lymphoma; Refractory Acute Lymphoblastic Leukemia; Refractory Adult Acute Lymphoblastic Leukemia; Secondary Acute Myeloid Leukemia; Therapy-Related Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2016-05-19 | PHASE2 |
| NCT06996119 | RECRUITING | Acute Myeloid Leukemia; Graft Versus Host Disease; Myelodysplastic Syndrome |
City of Hope Medical Center |
2026-06-12 | PHASE1 |
| NCT05052528 | RECRUITING | Recurrent Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma |
University of California, Davis |
2021-09-17 | PHASE1 |
| NCT04262843 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; High Risk Myelodysplastic Syndrome; Myelodysplastic Syndrome |
City of Hope Medical Center |
2020-02-07 | PHASE2 |
| NCT04754945 | ACTIVE_NOT_RECRUITING | AL Amyloidosis |
Emory University |
2021-04-28 | PHASE1 |
| NCT04370301 | RECRUITING | Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2021-02-09 | PHASE2 |
| NCT03449108 | ACTIVE_NOT_RECRUITING | Bone Sarcoma; Dedifferentiated Chondrosarcoma; Giant Cell Tumor of Bone; Malignancy in Giant Cell Tumor of Bone; Malignant Solid Neoplasm; Ovarian Carcinosarcoma; Platinum-Resistant Ovarian Carcinoma; Poorly Differentiated Thyroid Gland Carcinoma; Recurrent Osteosarcoma; Recurrent Ovarian Carcinoma; Refractory Osteosarcoma; Soft Tissue Sarcoma; Thyroid Gland Anaplastic Carcinoma; Thyroid Gland Squamous Cell Carcinoma; Undifferentiated High Grade Pleomorphic Sarcoma of Bone; Triple Negative Breast Cancer |
M.D. Anderson Cancer Center |
2018-04-27 | PHASE2 |
| NCT03118492 | ACTIVE_NOT_RECRUITING | Secondary Myelofibrosis |
City of Hope Medical Center |
2017-06-21 | PHASE1 |
| NCT07583303 | NOT_YET_RECRUITING | Recurrent Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia |
City of Hope Medical Center |
2026-12-14 | PHASE1 |
| NCT04195633 | RECRUITING | Acute Leukemia; Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Adult Diffuse Large Cell Lymphoma; Anaplastic Large Cell Lymphoma; Burkitt Lymphoma; Chronic Myeloid Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Hodgkin Lymphoma; Lymphoblastic Lymphoma; Lymphoplasmacytic Lymphoma; Mantle Cell Lymphoma; Mixed Phenotype Acute Leukemia; Myelodysplastic Syndrome; Prolymphocytic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Follicular Lymphoma; Refractory Marginal Zone Lymphoma; Refractory Small Lymphocytic Lymphoma |
Fred Hutchinson Cancer Center |
2021-01-25 | PHASE2 |
| NCT05157971 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia; Ph-Like Acute Lymphoblastic Leukemia |
City of Hope Medical Center |
2022-03-17 | PHASE1 |
| NCT04859946 | ACTIVE_NOT_RECRUITING | Hematologic and Lymphocytic Disorder |
M.D. Anderson Cancer Center |
2022-01-11 | PHASE2 |
| NCT07278856 | RECRUITING | Follicular Helper T-Cell Lymphoma; Follicular Helper T-Cell Lymphoma, Angioimmunoblastic-Type; Follicular Helper T-Cell Lymphoma, Follicular-Type; Follicular Helper T-Cell Lymphoma, Not Otherwise Specified; Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma; Peripheral T-Cell Lymphoma, Not Otherwise Specified |
City of Hope Medical Center |
2025-12-16 | PHASE1 |
| NCT06236139 | RECRUITING | Metastatic Castration-Resistant Prostate Carcinoma; Metastatic Prostate Adenocarcinoma; Stage IVB Prostate Cancer AJCC v8 |
Fred Hutchinson Cancer Center |
2024-11-26 | PHASE1; PHASE2 |
| NCT05950113 | WITHDRAWN | Recurrent Multiple Myeloma; Refractory Multiple Myeloma |
Jonsson Comprehensive Cancer Center |
2024-03-28 | PHASE1 |
| NCT05364762 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Chronic Myelomonocytic Leukemia; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Primary Myelofibrosis; Secondary Myelofibrosis |
City of Hope Medical Center |
2022-11-23 | PHASE2 |
| NCT03710772 | ACTIVE_NOT_RECRUITING | Mantle Cell Lymphoma |
M.D. Anderson Cancer Center |
2019-05-01 | PHASE2 |
| NCT03655002 | ACTIVE_NOT_RECRUITING | Recurrent Hepatocellular Carcinoma; Refractory Liver Carcinoma; Stage IV Hepatocellular Carcinoma AJCC v8; Stage IVA Hepatocellular Carcinoma AJCC v8; Stage IVB Hepatocellular Carcinoma AJCC v8 |
City of Hope Medical Center |
2019-05-17 | PHASE1 |
| NCT04799275 | ACTIVE_NOT_RECRUITING | Ann Arbor Stage III Diffuse Large B-Cell Lymphoma; Ann Arbor Stage IIX (Bulky) Diffuse Large B-Cell Lymphoma; Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma; Diffuse Large B-Cell Lymphoma Activated B-Cell Type; Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation; Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type; Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Grade 3b Follicular Lymphoma; HHV8-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements; High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements; High Grade B-Cell Lymphoma, Not Otherwise Specified; Intravascular Large B-Cell Lymphoma; Lymphoplasmacytic Lymphoma; Nodular Lymphocyte Predominant B-Cell Lymphoma; Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type; T-Cell/Histiocyte-Rich Large B-Cell Lymphoma; Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma |
National Cancer Institute (NCI) |
2021-05-20 | PHASE2; PHASE3 |
| NCT03147612 | ACTIVE_NOT_RECRUITING | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia With BCR-ABL1; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Recurrent Acute Lymphoblastic Leukemia; Refractory Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2018-02-08 | PHASE2 |
| NCT04375631 | RECRUITING | Recurrent Acute Myeloid Leukemia; Recurrent Chronic Myelomonocytic Leukemia; Recurrent Myelodysplastic Syndrome; Refractory Acute Myeloid Leukemia; Refractory Chronic Myelomonocytic Leukemia; Refractory Mixed Phenotype Acute Leukemia; Refractory Myelodysplastic Syndrome; Refractory Acute Leukemia of Ambiguous Lineage; Refractory Acute Undifferentiated Leukemia |
Fred Hutchinson Cancer Center |
2020-12-03 | PHASE1 |
| NCT04510051 | RECRUITING | Malignant Brain Neoplasm; Recurrent Malignant Brain Neoplasm; Refractory Malignant Brain Neoplasm |
City of Hope Medical Center |
2020-12-04 | PHASE1 |
| NCT03710421 | SUSPENDED | Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
City of Hope Medical Center |
2019-04-23 | PHASE1 |
| NCT04978584 | ACTIVE_NOT_RECRUITING | Diffuse Large B-Cell Lymphoma |
M.D. Anderson Cancer Center |
2022-03-03 | PHASE2 |
| NCT02981628 | ACTIVE_NOT_RECRUITING | Recurrent B Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory B Lymphoblastic Lymphoma |
Children's Oncology Group |
2017-06-19 | PHASE2 |
| NCT05873712 | RECRUITING | Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory Transformed Chronic Lymphocytic Leukemia; Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma; Recurrent Transformed B-Cell Non-Hodgkin Lymphoma; Recurrent Transformed Non-Hodgkin Lymphoma; Refractory Transformed Non-Hodgkin Lymphoma; Refractory Transformed B-cell Non-Hodgkin Lymphoma; Refractory Transformed |
Aseel Alsouqi |
2023-07-28 | PHASE2 |
| NCT04759586 | ACTIVE_NOT_RECRUITING | Primary Mediastinal Large B-Cell Lymphoma |
National Cancer Institute (NCI) |
2021-10-05 | PHASE3 |
| NCT07166419 | ACTIVE_NOT_RECRUITING | Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive; Recurrent Acute Lymphoblastic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Chronic Myeloid Leukemia, BCR-ABL1 Positive; Recurrent Indolent Non-Hodgkin Lymphoma; Recurrent Lymphoblastic Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory Acute Lymphoblastic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Chronic Myeloid Leukemia, BCR-ABL1 Positive; Refractory Indolent Non-Hodgkin Lymphoma; Refractory Lymphoblastic Lymphoma; Refractory Non-Hodgkin Lymphoma; Refractory Transformed Chronic Lymphocytic Leukemia |
Ohio State University Comprehensive Cancer Center |
2026-01-14 | PHASE1 |
| NCT04216524 | RECRUITING | Blastic Plasmacytoid Dendritic Cell Neoplasm |
M.D. Anderson Cancer Center |
2020-05-29 | PHASE2 |
| NCT04380831 | ACTIVE_NOT_RECRUITING | Systemic Scleroderma |
City of Hope Medical Center |
2022-02-24 | EARLY_PHASE1 |
| NCT06572631 | WITHDRAWN | Recurrent Acute Myeloid Leukemia; Recurrent Myelodysplastic Syndrome; Refractory Acute Myeloid Leukemia; Refractory Myelodysplastic Syndrome |
City of Hope Medical Center |
2025-06-07 | PHASE1 |
| NCT06447987 | SUSPENDED | Recurrent Acute Lymphoblastic Leukemia; Refractory Acute Lymphoblastic Leukemia |
City of Hope Medical Center |
2024-11-06 | PHASE1 |
| NCT06249191 | RECRUITING | Diffuse Large B-Cell Lymphoma; High Grade B-Cell Lymphoma |
OHSU Knight Cancer Institute |
2024-06-13 | PHASE1; PHASE2 |
| NCT05702853 | RECRUITING | B-cell Non Hodgkin Lymphoma; Chronic Lymphocytic Leukemia |
Medical University of South Carolina |
2023-11-06 | PHASE1; PHASE2 |
| NCT02877303 | RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2016-11-01 | PHASE2 |
| NCT00501826 | RECRUITING | T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2007-07-11 | PHASE2 |
| NCT04848064 | RECRUITING | Recurrent Adult T-Cell Leukemia/Lymphoma; Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma; Refractory Adult T-Cell Leukemia/Lymphoma; Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma |
John Reneau |
2022-05-06 | PHASE1 |
| NCT05455697 | ACTIVE_NOT_RECRUITING | Diffuse Large B-Cell Lymphoma; Grade 3b Follicular Lymphoma; High Grade B-Cell Lymphoma |
University of Washington |
2023-01-26 | PHASE1; PHASE2 |
| NCT05600686 | RECRUITING | Double-Expressor Lymphoma; High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements; High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements |
University of California, Davis |
2023-05-24 | PHASE2 |
| NCT04119024 | RECRUITING | Metastatic Malignant Solid Neoplasm; Metastatic Melanoma; Pathologic Stage IIIC Cutaneous Melanoma AJCC v8; Pathologic Stage IV Cutaneous Melanoma AJCC v8; Recurrent Malignant Solid Neoplasm; Refractory Malignant Solid Neoplasm; Uveal Melanoma; Acral Melanoma; Neuroendocrine Tumors; Paraganglioma; Pheochromocytoma; Adrenocortical Carcinoma; Pancreatic Neuroendocrine Tumor; Thyroid Cancer; Breast Cancer; Lung Adenocarcinoma; Head and Neck Squamous Cell Carcinoma |
Anusha Kalbasi |
2025-10-07 | PHASE1 |
| NCT02176967 | ACTIVE_NOT_RECRUITING | Ganglioneuroblastoma; Localized Resectable Neuroblastoma; Localized Unresectable Neuroblastoma; Neuroblastoma |
Children's Oncology Group |
2014-08-08 | PHASE3 |
| NCT06210750 | WITHDRAWN | T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
National Cancer Institute (NCI) |
2024-08-09 | PHASE2 |
| NCT05707273 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia |
City of Hope Medical Center |
2023-04-26 | PHASE1 |
| NCT05672173 | ACTIVE_NOT_RECRUITING | Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory Transformed Chronic Lymphocytic Leukemia; Richter Syndrome |
City of Hope Medical Center |
2023-06-02 | PHASE2 |
| NCT03467386 | SUSPENDED | Acute Myeloid Leukemia |
City of Hope Medical Center |
2018-03-19 | PHASE1 |
| NCT02153580 | ACTIVE_NOT_RECRUITING | B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma; B-Cell Prolymphocytic Leukemia; High Grade B-Cell Lymphoma, Not Otherwise Specified; Post-Transplant Lymphoproliferative Disorder; Recurrent Adult Burkitt Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Follicular Lymphoma; Recurrent Hairy Cell Leukemia; Recurrent Lymphoplasmacytic Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma |
City of Hope Medical Center |
2014-09-24 | PHASE1 |
| NCT04994132 | ACTIVE_NOT_RECRUITING | Alveolar Rhabdomyosarcoma; Botryoid-Type Embryonal Rhabdomyosarcoma; Embryonal Rhabdomyosarcoma; Metastatic Embryonal Rhabdomyosarcoma; Metastatic Rhabdomyosarcoma; Solid Alveolar Rhabdomyosarcoma; Spindle Cell Rhabdomyosarcoma; Spindle Cell/Sclerosing Rhabdomyosarcoma |
Children's Oncology Group |
2021-09-14 | PHASE3 |
| NCT03007147 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia; Mixed Phenotype Acute Leukemia; T Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2017-08-08 | PHASE3 |
| NCT06820957 | ACTIVE_NOT_RECRUITING | CIC-Rearranged Sarcoma; Metastatic Ewing Sarcoma; Metastatic High Grade Sarcoma; Metastatic Undifferentiated Round Cell Sarcoma; Metastatic Undifferentiated Sarcoma, Not Otherwise Specified; Round Cell Sarcoma With EWSR1-non-ETS Fusion; Sarcoma With BCOR Genetic Alterations |
Children's Oncology Group |
2025-11-10 | PHASE2; PHASE3 |
| NCT05457556 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Mixed Phenotype Acute Leukemia; Myelodysplastic Syndrome |
Children's Oncology Group |
2023-03-15 | PHASE3 |
| NCT04850495 | ACTIVE_NOT_RECRUITING | Diffuse Large B-Cell Lymphoma; Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma |
Yazeed Sawalha |
2021-11-16 | PHASE1 |
| NCT06203912 | COMPLETED | Recurrent Multiple Myeloma; Refractory Multiple Myeloma |
Elvira Umyarova |
2024-03-05 | PHASE1 |
| NCT03808610 | TERMINATED | Recurrent B Acute Lymphoblastic Leukemia; Recurrent T Acute Lymphoblastic Leukemia; Refractory B Acute Lymphoblastic Leukemia; Refractory T Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2019-04-03 | PHASE1; PHASE2 |
| NCT05453500 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative |
University of Washington |
2023-03-27 | PHASE2 |
| NCT04384692 | ACTIVE_NOT_RECRUITING | Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2020-12-18 | PHASE2 |
| NCT03420963 | TERMINATED | Recurrent Cutaneous Melanoma; Recurrent Lip and Oral Cavity Carcinoma; Recurrent Malignant Endocrine Neoplasm; Recurrent Malignant Female Reproductive System Neoplasm; Recurrent Malignant Male Reproductive System Neoplasm; Recurrent Malignant Mesothelioma; Recurrent Malignant Neoplasm of Multiple Primary Sites; Recurrent Malignant Oral Neoplasm; Recurrent Malignant Pharyngeal Neoplasm; Recurrent Malignant Skin Neoplasm; Recurrent Malignant Soft Tissue Neoplasm; Recurrent Malignant Solid Neoplasm; Recurrent Malignant Thyroid Gland Neoplasm; Recurrent Malignant Urinary System Neoplasm; Refractory Cutaneous Melanoma; Refractory Malignant Bone Neoplasm; Refractory Malignant Endocrine Neoplasm; Refractory Malignant Female Reproductive System Neoplasm; Refractory Malignant Male Reproductive System Neoplasm; Refractory Malignant Mesothelioma; Refractory Malignant Neoplasm of Multiple Primary Sites; Refractory Malignant Oral Neoplasm; Refractory Malignant Pharyngeal Neoplasm; Refractory Malignant Skin Neoplasm; Refractory Malignant Soft Tissue Neoplasm; Refractory Malignant Solid Neoplasm; Refractory Malignant Thyroid Gland Neoplasm; Refractory Malignant Urinary System Neoplasm |
M.D. Anderson Cancer Center |
2018-08-31 | PHASE1 |
| NCT04205838 | TERMINATED | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; High Grade B-Cell Lymphoma; Progressive Disease; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent High Grade B-Cell Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory High Grade B-Cell Lymphoma; Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma |
Jonsson Comprehensive Cancer Center |
2020-03-04 | PHASE2 |
| NCT03749018 | ACTIVE_NOT_RECRUITING | Aggressive Non-Hodgkin Lymphoma; Ann Arbor Stage I Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Ann Arbor Stage II B-Cell Non-Hodgkin Lymphoma; Ann Arbor Stage II Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Ann Arbor Stage III B-Cell Non-Hodgkin Lymphoma; Ann Arbor Stage III Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma; Ann Arbor Stage IV Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Diffuse Large B-Cell Lymphoma; High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements; High Grade B-Cell Lymphoma, Not Otherwise Specified; Indolent Non-Hodgkin Lymphoma; Mediastinal B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma; Transformed Non-Hodgkin Lymphoma |
David Bond, MD |
2019-01-02 | PHASE2 |
| NCT03269669 | ACTIVE_NOT_RECRUITING | Grade 1 Follicular Lymphoma; Grade 2 Follicular Lymphoma; Grade 3a Follicular Lymphoma; Recurrent Follicular Lymphoma; Refractory Follicular Lymphoma |
National Cancer Institute (NCI) |
2018-01-23 | PHASE2 |
| NCT02488967 | ACTIVE_NOT_RECRUITING | Breast Adenocarcinoma; Estrogen Receptor Negative; HER2/Neu Negative; Progesterone Receptor Negative; Stage IB Breast Cancer; Stage IIA Breast Cancer; Stage IIB Breast Cancer; Stage IIIA Breast Cancer; Stage IIIC Breast Cancer; Triple-Negative Breast Carcinoma |
NRG Oncology |
2015-07-26 | PHASE3 |
| NCT04177004 | ACTIVE_NOT_RECRUITING | Allogeneic Hematopoietic Stem Cell Transplant Recipient; Hematopoietic and Lymphoid Cell Neoplasm |
City of Hope Medical Center |
2021-04-30 | PHASE1 |
| NCT02654119 | COMPLETED | HER2 Positive Breast Carcinoma; Stage I Breast Cancer AJCC v7; Stage IA Breast Cancer AJCC v7; Stage IB Breast Cancer AJCC v7; Stage II Breast Cancer AJCC v6 and v7; Stage IIA Breast Cancer AJCC v6 and v7; Stage IIB Breast Cancer AJCC v6 and v7 |
University of Nebraska |
2015-12-11 | PHASE2 |
| NCT04074746 | COMPLETED | Recurrent Anaplastic Large Cell Lymphoma; Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Classic Hodgkin Lymphoma; Recurrent Mycosis Fungoides; Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified; Refractory Anaplastic Large Cell Lymphoma; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Classic Hodgkin Lymphoma; Refractory Mycosis Fungoides; Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified |
M.D. Anderson Cancer Center |
2020-07-18 | PHASE1; PHASE2 |
| NCT05359211 | ACTIVE_NOT_RECRUITING | Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Recurrent Grade 3b Follicular Lymphoma; Recurrent Primary Mediastinal Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Refractory Grade 3b Follicular Lymphoma; Refractory Primary Mediastinal Large B-Cell Lymphoma; Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma |
Fred Hutchinson Cancer Center |
2022-12-08 | PHASE1 |
| NCT04626791 | ACTIVE_NOT_RECRUITING | Mantle Cell Lymphoma |
Academic and Community Cancer Research United |
2021-08-03 | PHASE2 |
| NCT06151847 | COMPLETED | Clinical Stage IV Cutaneous Melanoma AJCC v8; Metastatic Melanoma; Pathologic Stage IIIC Cutaneous Melanoma AJCC v8; Unresectable Melanoma |
University of Kansas Medical Center |
2023-12-21 | PHASE2 |
| NCT04860960 | UNKNOWN | Niemann-Pick Disease, Type C1 |
Cyclo Therapeutics, Inc. |
2021-07-20 | PHASE3 |
| NCT02446964 | COMPLETED | Adult Acute Lymphoblastic Leukemia in Complete Remission; Acute Myeloid Leukemia in Remission; Previously Treated Myelodysplastic Syndrome; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Childhood Acute Lymphoblastic Leukemia in Complete Remission |
City of Hope Medical Center |
2015-06-25 | PHASE1 |
| NCT03101748 | TERMINATED | Breast Inflammatory Carcinoma; Locally Advanced Breast Carcinoma; Metastatic Breast Carcinoma; Stage III Breast Cancer AJCC v7; Stage IIIA Breast Cancer AJCC v7; Stage IIIB Breast Cancer AJCC v7; Stage IIIC Breast Cancer AJCC v7; Stage IV Breast Cancer AJCC v6 and v7 |
M.D. Anderson Cancer Center |
2018-02-19 | PHASE1; PHASE2 |
| NCT03246906 | TERMINATED | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Aggressive Non-Hodgkin Lymphoma; Chronic Lymphocytic Leukemia; Diffuse Large B-Cell Lymphoma; Mantle Cell Lymphoma; Myelodysplastic Syndrome; Myelodysplastic/Myeloproliferative Neoplasm; Prolymphocytic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Recurrent Hodgkin Lymphoma; Recurrent Plasma Cell Myeloma; Recurrent Small Lymphocytic Lymphoma; Recurrent Waldenstrom Macroglobulinemia; Hematologic and Lymphocytic Disorder; Blastic Plasmacytoid Dendritic Cell Neoplasm |
Fred Hutchinson Cancer Center |
2017-09-11 | PHASE2 |
| NCT05479578 | ACTIVE_NOT_RECRUITING | Castration-Resistant Prostate Carcinoma; Metastatic Prostate Adenocarcinoma; Stage IVB Prostate Cancer American Joint Committee on Cancer (AJCC) V8 |
Rashmi Verma, MD |
2022-06-29 | PHASE1 |
| NCT03241940 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia; CD19 Positive; Minimal Residual Disease; Philadelphia Chromosome Positive; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; Refractory Acute Lymphoblastic Leukemia |
Stanford University |
2017-10-20 | PHASE1 |
| NCT02220985 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Biphenotypic Leukemia; Acute Leukemia of Ambiguous Lineage; Acute Undifferentiated Leukemia; Allogeneic Hematopoietic Stem Cell Transplant Recipient; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Blastic Plasmacytoid Dendritic Cell Neoplasm; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Donor; Lymphoblastic Lymphoma; Myelodysplastic Syndrome With Excess Blasts; Myelodysplastic Syndrome With Excess Blasts-1; Myelodysplastic Syndrome With Excess Blasts-2; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia in Remission |
Fred Hutchinson Cancer Center |
2015-03-23 | PHASE2 |
| NCT03712878 | COMPLETED | Hematopoietic and Lymphoid Cell Neoplasm |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2018-09-19 | PHASE2 |
| NCT03012100 | ACTIVE_NOT_RECRUITING | Bilateral Breast Carcinoma; Breast Inflammatory Carcinoma; Stage IB Breast Cancer AJCC v7; Stage II Breast Cancer AJCC v6 and v7; Stage IIA Breast Cancer AJCC v6 and v7; Stage IIB Breast Cancer AJCC v6 and v7; Stage III Breast Cancer AJCC v7; Stage IIIA Breast Cancer AJCC v7; Stage IIIB Breast Cancer AJCC v7; Stage IIIC Breast Cancer AJCC v7; Triple-Negative Breast Carcinoma; Unilateral Breast Carcinoma |
Academic and Community Cancer Research United |
2017-03-31 | PHASE2 |
| NCT06343376 | TERMINATED | Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Follicular Lymphoma; Recurrent High Grade B-Cell Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Transformed Chronic Lymphocytic Leukemia; Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Diffuse Large B-Cell Lymphoma; Refractory Follicular Lymphoma; Refractory High Grade B-Cell Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Transformed Chronic Lymphocytic Leukemia; Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma |
Roswell Park Cancer Institute |
2024-11-26 | PHASE1 |
| NCT03704714 | SUSPENDED | Aggressive Non-Hodgkin Lymphoma; B-Cell Non-Hodgkin Lymphoma; CD20 Positive; Diffuse Large B-Cell Lymphoma Unclassifiable; Intravascular Large B-Cell Lymphoma; Primary Mediastinal (Thymic) Large B-Cell Lymphoma; T-Cell/Histiocyte-Rich Large B-Cell Lymphoma; Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma |
Northwestern University |
2018-11-20 | PHASE1; PHASE2 |
| NCT02684708 | COMPLETED | Classical Hodgkin Lymphoma |
University of Giessen |
2015-10-01 | PHASE3 |
| NCT03220022 | ACTIVE_NOT_RECRUITING | AIDS-Related Lymphoma; Ann Arbor Stage II Diffuse Large B-Cell Lymphoma; Ann Arbor Stage III Diffuse Large B-Cell Lymphoma; Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma |
National Cancer Institute (NCI) |
2018-03-16 | PHASE1 |
| NCT02419495 | TERMINATED | Advanced Malignant Solid Neoplasm; Clinical Stage III Cutaneous Melanoma AJCC v8; Clinical Stage IV Cutaneous Melanoma AJCC v8; Fallopian Tube Carcinoma; Metastatic Lung Non-Small Cell Carcinoma; Metastatic Malignant Solid Neoplasm; Metastatic Melanoma; Metastatic Renal Cell Carcinoma; Ovarian Carcinoma; Pathologic Stage III Cutaneous Melanoma AJCC v8; Pathologic Stage IIIA Cutaneous Melanoma AJCC v8; Pathologic Stage IIIB Cutaneous Melanoma AJCC v8; Pathologic Stage IIIC Cutaneous Melanoma AJCC v8; Pathologic Stage IIID Cutaneous Melanoma AJCC v8; Pathologic Stage IV Cutaneous Melanoma AJCC v8; Primary Peritoneal Carcinoma; Stage III Lung Cancer AJCC v8; Stage III Renal Cell Cancer AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIB Lung Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8; Stage IV Renal Cell Cancer AJCC v8; Stage IVA Lung Cancer AJCC v8; Stage IVB Lung Cancer AJCC v8; Triple-Negative Breast Carcinoma; Unresectable Lung Non-Small Cell Carcinoma; Unresectable Melanoma; Unresectable Renal Cell Carcinoma |
M.D. Anderson Cancer Center |
2015-06-26 | PHASE1 |
| NCT03610490 | TERMINATED | Malignant Solid Neoplasm; Metastatic Colorectal Adenocarcinoma; Metastatic Ovarian Carcinoma; Metastatic Pancreatic Ductal Adenocarcinoma; Platinum-Resistant Ovarian Carcinoma; Recurrent High Grade Ovarian Serous Adenocarcinoma; Recurrent Ovarian Carcinosarcoma; Refractory Colorectal Carcinoma; Stage IV Colorectal Cancer AJCC v8; Stage IVA Colorectal Cancer AJCC v8; Stage IVB Colorectal Cancer AJCC v8; Stage IVC Colorectal Cancer AJCC v8 |
M.D. Anderson Cancer Center |
2018-10-16 | PHASE2 |
| NCT05032183 | TERMINATED | Recurrent Adult Lymphoblastic Lymphoma; Recurrent B Acute Lymphoblastic Leukemia; Recurrent T Acute Lymphoblastic Leukemia; Refractory B Acute Lymphoblastic Leukemia; Refractory Lymphoblastic Lymphoma; Refractory T Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2022-02-17 | PHASE1; PHASE2 |
| NCT02443077 | ACTIVE_NOT_RECRUITING | Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type; Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type |
National Cancer Institute (NCI) |
2016-10-12 | PHASE3 |
| NCT04432506 | COMPLETED | Hematopoietic and Lymphoid Cell Neoplasm; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent High Grade B-Cell Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory High Grade B-Cell Lymphoma; Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma |
M.D. Anderson Cancer Center |
2020-07-27 | PHASE2 |
| NCT02027935 | COMPLETED | Metastatic Melanoma; Stage IV Cutaneous Melanoma AJCC v6 and v7 |
M.D. Anderson Cancer Center |
2015-01-22 | PHASE2 |
| NCT01898117 | ACTIVE_NOT_RECRUITING | Breast Cancer |
The Netherlands Cancer Institute |
2013-07 | PHASE2 |
| NCT05607615 | UNKNOWN | Alzheimer's Disease |
Cyclo Therapeutics, Inc. |
2022-09-23 | PHASE2 |
| NCT03277729 | ACTIVE_NOT_RECRUITING | Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Follicular Lymphoma; Recurrent Lymphoplasmacytic Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Follicular Lymphoma; Refractory Lymphoplasmacytic Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Transformed Non-Hodgkin Lymphoma; Recurrent Transformed B-Cell Non-Hodgkin Lymphoma; Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory Marginal Zone Lymphoma; Refractory Transformed B-Cell Non-Hodgkin Lymphoma; Refractory Transformed Chronic Lymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Small Lymphocytic Lymphoma; Recurrent Central Nervous System Lymphoma; Refractory Central Nervous System Lymphoma |
Fred Hutchinson Cancer Center |
2017-12-05 | PHASE1; PHASE2 |
| NCT03505762 | ACTIVE_NOT_RECRUITING | B-Cell Non-Hodgkin Lymphoma |
Wake Forest University Health Sciences |
2018-07-19 | PHASE2 |
| NCT00390793 | COMPLETED | Acute Lymphoblastic Leukemia; BCR-ABL1 Fusion Protein Expression; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Philadelphia Chromosome Positive; Recurrent Acute Lymphoblastic Leukemia; t(9;22) |
M.D. Anderson Cancer Center |
2006-09-28 | PHASE2 |
| NCT00719888 | COMPLETED | Acute Biphenotypic Leukemia; Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Burkitt Lymphoma; Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Follicular Lymphoma; Lymphoblastic Lymphoma; Lymphoplasmacytic Lymphoma; Mantle Cell Lymphoma; Marginal Zone Lymphoma; Myelodysplastic Syndrome; Myelofibrosis; Non-Hodgkin Lymphoma; Plasma Cell Myeloma; Prolymphocytic Leukemia; Refractory Anemia; Small Lymphocytic Lymphoma |
Fred Hutchinson Cancer Center |
2005-11-18 | PHASE2 |
| NCT03318900 | COMPLETED | COL6A3 Positive; HLA-A*0201 Positive Cells Present; PRAME Positive; Recurrent Ovarian Carcinoma |
M.D. Anderson Cancer Center |
2018-09-04 | PHASE1; PHASE2 |
| NCT03252600 | UNKNOWN | Recurrent Primary Amyloidosis |
Barbara Ann Karmanos Cancer Institute |
2017-08-25 | PHASE2 |
| NCT04752163 | TERMINATED | Hematopoietic and Lymphoid Cell Neoplasm; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Myelomonocytic Leukemia; Recurrent Myelodysplastic Syndrome; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia; Refractory Chronic Myelomonocytic Leukemia; Refractory Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2021-03-25 | PHASE1; PHASE2 |
| NCT01897441 | TERMINATED | Stage IIA Breast Cancer; Stage IIB Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer |
Albert Einstein College of Medicine |
2013-06 | |
| NCT04323956 | ACTIVE_NOT_RECRUITING | Ann Arbor Stage II Diffuse Large B-Cell Lymphoma; Ann Arbor Stage II Follicular Lymphoma; Ann Arbor Stage II Marginal Zone Lymphoma; Ann Arbor Stage III Diffuse Large B-Cell Lymphoma; Ann Arbor Stage III Follicular Lymphoma; Ann Arbor Stage III Marginal Zone Lymphoma; Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma; Ann Arbor Stage IV Follicular Lymphoma; Ann Arbor Stage IV Marginal Zone Lymphoma; Diffuse Large B-Cell Lymphoma; High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements; High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements; Indolent Non-Hodgkin Lymphoma |
Mayo Clinic |
2020-06-15 | PHASE1 |
| NCT02586038 | COMPLETED | Multiple Myeloma |
Mario Boccadoro |
2015-10 | PHASE2 |
| NCT03602898 | WITHDRAWN | Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Hematopoietic and Lymphoid System Neoplasm; Myelodysplastic Syndrome; Myelofibrosis; Myeloproliferative Neoplasm; Recurrent Acute Myeloid Leukemia; Recurrent Hodgkin Lymphoma; Recurrent Non-Hodgkin Lymphoma; Refractory Acute Myeloid Leukemia; Therapy-Related Acute Myeloid Leukemia |
Fred Hutchinson Cancer Center |
2021-06-01 | PHASE2 |
| NCT01413100 | COMPLETED | Systemic Scleroderma |
Fred Hutchinson Cancer Center |
2011-09-15 | PHASE2 |
| NCT03333486 | TERMINATED | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Leukemia in Remission; Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Acute Myeloid Leukemia With FLT3/ITD Mutation; Acute Myeloid Leukemia With Gene Mutations; Aplastic Anemia; B-Cell Non-Hodgkin Lymphoma; CD40 Ligand Deficiency; Chronic Granulomatous Disease; Chronic Leukemia in Remission; Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Congenital Amegakaryocytic Thrombocytopenia; Congenital Neutropenia; Congenital Pure Red Cell Aplasia; Glanzmann Thrombasthenia; Immunodeficiency Syndrome; Myelodysplastic Syndrome; Myelofibrosis; Myeloproliferative Neoplasm; Paroxysmal Nocturnal Hemoglobinuria; Plasma Cell Myeloma; Polycythemia Vera; Recurrent Non-Hodgkin Lymphoma; Refractory Non-Hodgkin Lymphoma; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndrome; Severe Aplastic Anemia; Shwachman-Diamond Syndrome; Sickle Cell Disease; T-Cell Non-Hodgkin Lymphoma; Thalassemia; Waldenstrom Macroglobulinemia; Wiskott-Aldrich Syndrome |
Roswell Park Cancer Institute |
2017-12-07 | PHASE2 |
| NCT03192397 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukemia in Remission; Adult Acute Lymphoblastic Leukemia in Complete Remission; Chronic Myelogenous Leukemia, BCR-ABL1 Positive in Remission; Chronic Myelomonocytic Leukemia in Remission; Graft Versus Host Disease; Hodgkin Lymphoma; Minimal Residual Disease; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Non-Hodgkin Lymphoma; Plasma Cell Myeloma; Severe Aplastic Anemia; Waldenstrom Macroglobulinemia |
Roswell Park Cancer Institute |
2017-08-09 | PHASE1; PHASE2 |
| NCT05177796 | WITHDRAWN | Anatomic Stage III Breast Cancer AJCC v8; Anatomic Stage IIIA Breast Cancer AJCC v8; Anatomic Stage IIIB Breast Cancer AJCC v8; Anatomic Stage IIIC Breast Cancer AJCC v8; Anatomic Stage IV Breast Cancer AJCC v8; Breast Inflammatory Carcinoma; Invasive Breast Carcinoma; Prognostic Stage III Breast Cancer AJCC v8; Prognostic Stage IIIA Breast Cancer AJCC v8; Prognostic Stage IIIB Breast Cancer AJCC v8; Prognostic Stage IIIC Breast Cancer AJCC v8; Prognostic Stage IV Breast Cancer AJCC v8; Triple-Negative Breast Carcinoma |
M.D. Anderson Cancer Center |
2022-03-11 | PHASE2 |
| NCT05176470 | ACTIVE_NOT_RECRUITING | Locally Advanced Melanoma; Pathologic Stage IIIB Cutaneous Melanoma AJCC v8; Pathologic Stage IIIC Cutaneous Melanoma AJCC v8; Pathologic Stage IIID Cutaneous Melanoma AJCC v8; Stage IV Melanoma |
Richard Wu |
2022-07-01 | PHASE1 |
| NCT02567435 | ACTIVE_NOT_RECRUITING | Alveolar Rhabdomyosarcoma; Botryoid-Type Embryonal Rhabdomyosarcoma; Embryonal Rhabdomyosarcoma; Rhabdomyosarcoma; Sclerosing Rhabdomyosarcoma; Spindle Cell Rhabdomyosarcoma |
National Cancer Institute (NCI) |
2016-06-01 | PHASE3 |
| NCT02003222 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative |
National Cancer Institute (NCI) |
2014-05-19 | PHASE3 |
| NCT03233854 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia; CD19 Positive; Minimal Residual Disease; Philadelphia Chromosome Positive |
Stanford University |
2017-09-01 | PHASE1 |
| NCT00075387 | UNKNOWN | Malignant Glioma |
OHSU Knight Cancer Institute |
2003-03-07 | PHASE2 |
| NCT01415882 | COMPLETED | Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
Mayo Clinic |
2012-01-31 | PHASE2 |
| NCT01740557 | COMPLETED | Metastatic Melanoma; Stage III Cutaneous Melanoma AJCC v7; Stage IV Cutaneous Melanoma AJCC v6 and v7 |
M.D. Anderson Cancer Center |
2015-01-28 | PHASE1; PHASE2 |
| NCT03103971 | TERMINATED | Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Refractory Adult Acute Lymphoblastic Leukemia; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Recurrent Transformed Non-Hodgkin Lymphoma; Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements; Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements; Recurrent B Acute Lymphoblastic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; Refractory B Acute Lymphoblastic Leukemia; Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements |
Fred Hutchinson Cancer Center |
2017-11-03 | PHASE1 |
| NCT01783535 | ACTIVE_NOT_RECRUITING | Retinoblastoma |
St. Jude Children's Research Hospital |
2013-06-19 | PHASE2 |
| NCT02199184 | COMPLETED | AIDS-Related Burkitt Lymphoma; Atypical Burkitt/Burkitt-Like Lymphoma; High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements; Recurrent Acute Lymphoblastic Leukemia; Recurrent Burkitt Lymphoma; Refractory Acute Lymphoblastic Leukemia; Refractory Burkitt Lymphoma |
M.D. Anderson Cancer Center |
2015-01-14 | PHASE2 |
| NCT02960646 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Aplastic Anemia; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Lymphoblastic Lymphoma; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Plasma Cell Myeloma; Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma; Recurrent Hodgkin Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Plasma Cell Myeloma; Therapy-Related Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2017-01-18 | PHASE1 |
| NCT03918499 | COMPLETED | Clinical Stage IV Gastric Cancer AJCC v8; Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVA Gastric Cancer AJCC v8; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVB Gastric Cancer AJCC v8; Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8; Metastatic Gastric Adenocarcinoma; Metastatic Gastroesophageal Junction Adenocarcinoma; Pathologic Stage IV Gastric Cancer AJCC v8; Pathologic Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Pathologic Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8; Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8; Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8; Postneoadjuvant Therapy Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Postneoadjuvant Therapy Stage IVB Gastroesophageal Junction Adenocarcinoma AJCC v8; Recurrent Gastric Adenocarcinoma; Recurrent Gastroesophageal Junction Adenocarcinoma |
City of Hope Medical Center |
2019-04-19 | PHASE1; PHASE2 |
| NCT02883049 | COMPLETED | B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, BCR-ABL1-Like; Central Nervous System Leukemia; Testicular Leukemia |
National Cancer Institute (NCI) |
2012-02-29 | PHASE3 |
| NCT03068624 | UNKNOWN | Metastatic Malignant Neoplasm in the Liver; Metastatic Uveal Melanoma |
M.D. Anderson Cancer Center |
2017-09-08 | PHASE1 |
| NCT03531281 | WITHDRAWN | Hematopoietic and Lymphoid Cell Neoplasm; Hematopoietic Cell Transplantation Recipient |
City of Hope Medical Center |
2018-12-30 | PHASE1 |
| NCT02251821 | COMPLETED | Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2014-10-20 | PHASE2 |
| NCT03450122 | COMPLETED | HLA-A*0201 Positive Cells Present; NY-ESO-1 Positive Tumor Cells Present; Recurrent Myxoid Liposarcoma; Recurrent Synovial Sarcoma |
M.D. Anderson Cancer Center |
2018-09-13 | PHASE1 |
| NCT04776850 | WITHDRAWN | Beta Thalassemia Major; Sickle Beta 0 Thalassemia; Sickle Beta Plus Thalassemia; Sickle Beta Thalassemia; Sickle Cell Disease; Sickle Cell-SS Disease |
M.D. Anderson Cancer Center |
2020-12-29 | EARLY_PHASE1 |
| NCT04029038 | WITHDRAWN | CD19 Positive; CD22 Positive; Minimal Residual Disease; Progressive Disease; Recurrent B Acute Lymphoblastic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Non-Hodgkin Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Non-Hodgkin Lymphoma |
M.D. Anderson Cancer Center |
2019-05-15 | PHASE1; PHASE2 |
| NCT04083170 | TERMINATED | Acute Erythroid Leukemia; Acute Lymphoblastic Leukemia; Acute Megakaryoblastic Leukemia; Acute Myeloid Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Hematopoietic and Lymphoid Cell Neoplasm; HIV Infection; Myelodysplastic Syndrome; Myelodysplastic Syndrome With Excess Blasts; Non-Hodgkin Lymphoma; Refractory Anemia |
Fred Hutchinson Cancer Center |
2022-10-06 | PHASE2 |
| NCT02636322 | COMPLETED | Diffuse Large B-Cell Lymphoma Unclassifiable |
M.D. Anderson Cancer Center |
2016-03-29 | PHASE2 |
| NCT02500576 | COMPLETED | Metastatic Melanoma; Stage IIIB Cutaneous Melanoma AJCC v7; Stage IIIC Cutaneous Melanoma AJCC v7; Stage IV Cutaneous Melanoma AJCC v6 and v7 |
M.D. Anderson Cancer Center |
2015-08-07 | PHASE2 |
| NCT03096782 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Biphenotypic Leukemia; Acute Leukemia; Acute Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Chemotherapy-Related Leukemia; Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Hodgkin Lymphoma; Langerhans Cell Histiocytosis; Minimal Residual Disease; Myelodysplastic Syndrome; Myelodysplastic Syndrome With Excess Blasts; Non-Hodgkin Lymphoma; Recurrent Hodgkin Lymphoma; Refractory Acute Lymphoblastic Leukemia; Refractory Myelodysplastic Syndrome; Small Lymphocytic Lymphoma; Therapy-Related Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2017-10-13 | PHASE2 |
| NCT03873805 | ACTIVE_NOT_RECRUITING | Castration-Resistant Prostate Carcinoma; Metastatic Prostate Carcinoma; Stage IV Prostate Cancer AJCC v8; Stage IVA Prostate Cancer AJCC v8; Stage IVB Prostate Cancer AJCC v8 |
City of Hope Medical Center |
2019-08-20 | PHASE1 |
| NCT04639245 | TERMINATED | Anatomic Stage IV Breast Cancer AJCC v8; Metastatic Lung Non-Small Cell Carcinoma; Metastatic Malignant Solid Neoplasm; Metastatic Triple-Negative Breast Carcinoma; Metastatic Urothelial Carcinoma; Stage IV Lung Cancer AJCC v8 |
Fred Hutchinson Cancer Center |
2021-07-19 | PHASE1; PHASE2 |
| NCT04081389 | COMPLETED | Anatomic Stage 0 Breast Cancer AJCC v8; Anatomic Stage I Breast Cancer AJCC v8; Anatomic Stage IA Breast Cancer AJCC v8; Anatomic Stage IB Breast Cancer AJCC v8; Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage IIA Breast Cancer AJCC v8; Anatomic Stage IIB Breast Cancer AJCC v8; Early-Stage Breast Carcinoma; Estrogen Receptor Negative; HER2/Neu Negative; Progesterone Receptor Negative; Prognostic Stage 0 Breast Cancer AJCC v8; Prognostic Stage I Breast Cancer AJCC v8; Prognostic Stage IA Breast Cancer AJCC v8; Prognostic Stage IB Breast Cancer AJCC v8; Prognostic Stage II Breast Cancer AJCC v8; Prognostic Stage IIA Breast Cancer AJCC v8; Prognostic Stage IIB Breast Cancer AJCC v8; Triple-Negative Breast Carcinoma |
Roswell Park Cancer Institute |
2019-12-06 | PHASE1 |
| NCT01750073 | COMPLETED | Estrogen Receptor Negative; Estrogen Receptor Positive; HER2/Neu Negative; HER2/Neu Positive; Invasive Breast Carcinoma; Progesterone Receptor Negative; Progesterone Receptor Positive; Stage IA Breast Cancer; Stage II Breast Cancer; Stage IIA Breast Cancer; Stage IIB Breast Cancer; Stage III Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Triple-Negative Breast Carcinoma |
University of Nebraska |
2012-12-07 | PHASE2 |
| NCT03502577 | TERMINATED | Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
Fred Hutchinson Cancer Center |
2018-05-23 | PHASE1 |
| NCT01760655 | COMPLETED | Acute Myeloid Leukemia With FLT3/ITD Mutation; Acute Myeloid Leukemia With Gene Mutations; Acute Myeloid Leukemia With Inv(3) (q21.3;q26.2); GATA2, MECOM; Acute Myeloid Leukemia With t(6;9) (p23;q34.1); DEK-NUP214; Aplastic Anemia; Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Follicular Lymphoma; Hodgkin Lymphoma; Myelodysplastic Syndrome; Myelofibrosis; Myeloid Leukemia; Non-Hodgkin Lymphoma; Plasma Cell Myeloma; Polycythemia Vera; Recurrent Adult Acute Myeloid Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Therapy-Related Acute Myeloid Leukemia |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2012-12-24 | PHASE2 |
| NCT05521334 | COMPLETED | Refractory Glaucoma |
Helwan University |
2021-03-01 | |
| NCT03893071 | UNKNOWN | Niemann-Pick Disease, Type C1 |
Cyclo Therapeutics, Inc. |
2019-05-23 | PHASE1 |
| NCT01904136 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Acute Myeloid Leukemia With Gene Mutations; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; de Novo Myelodysplastic Syndrome; Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Therapy-Related Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2014-04-22 | PHASE1; PHASE2 |
| NCT06226428 | COMPLETED | Coronavirus |
Biogipuzkoa Health Research Institute |
2021-04-01 | |
| NCT03786783 | COMPLETED | Ganglioneuroblastoma; High Risk Neuroblastoma |
National Cancer Institute (NCI) |
2019-03-04 | PHASE2 |
| NCT02166463 | ACTIVE_NOT_RECRUITING | Ann Arbor Stage IIB Hodgkin Lymphoma; Ann Arbor Stage IIIB Hodgkin Lymphoma; Ann Arbor Stage IVA Hodgkin Lymphoma; Ann Arbor Stage IVB Hodgkin Lymphoma; Childhood Hodgkin Lymphoma; Classic Hodgkin Lymphoma |
National Cancer Institute (NCI) |
2015-03-19 | PHASE3 |
| NCT01096368 | COMPLETED | Anaplastic Ependymoma; Brain Ependymoma; Cellular Ependymoma; Clear Cell Ependymoma; Ependymoma; Papillary Ependymoma |
Children's Oncology Group |
2010-05-07 | PHASE3 |
| NCT03987997 | UNKNOWN | Weakness, Muscle |
Direction Centrale du Service de Santé des Armées |
2018-08-09 | |
| NCT02529813 | COMPLETED | Acute Biphenotypic Leukemia; Acute Lymphoblastic Leukemia; Blasts 5 Percent or More of Bone Marrow Nucleated Cells; CD19 Positive; Minimal Residual Disease; Non-Hodgkin Lymphoma; Small Lymphocytic Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage IV Chronic Lymphocytic Leukemia |
M.D. Anderson Cancer Center |
2015-12-16 | PHASE1 |
| NCT05314543 | Recruiting | Healthy Volunteers|Performance |
Centre Hospitalier Universitaire de Saint Etienne |
2021-11-29 | Not Applicable |
| NCT01619761 | UNKNOWN | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Biphenotypic Leukemia; Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia in Remission; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; DS Stage II Plasma Cell Myeloma; DS Stage III Plasma Cell Myeloma; High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements; ISS Stage II Plasma Cell Myeloma; ISS Stage III Plasma Cell Myeloma; Myelodysplastic Syndrome; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Hodgkin Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Acute Lymphoblastic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Hodgkin Lymphoma; Refractory Non-Hodgkin Lymphoma; Refractory Small Lymphocytic Lymphoma; Secondary Acute Myeloid Leukemia; Therapy-Related Acute Myeloid Leukemia; Therapy-Related Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2013-05-03 | PHASE1 |
| NCT04220008 | WITHDRAWN | Recurrent Aggressive Non-Hodgkin Lymphoma; Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Burkitt Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent High Grade B-Cell Lymphoma; Recurrent T-Cell Non-Hodgkin Lymphoma; Recurrent Transformed B-Cell Non-Hodgkin Lymphoma |
M.D. Anderson Cancer Center |
2021-10-29 | PHASE2 |
| NCT01028716 | TERMINATED | Acute Biphenotypic Leukemia; Acute Erythroid Leukemia in Remission; Acute Leukemia in Remission; Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukaemia With Prior Myelodysplastic Syndrome; Acute Myeloid Leukemia in Remission; Acute Myeloid Leukemia With FLT3/ITD Mutation; Acute Myeloid Leukemia With Inv(3)(Q21Q26.2); RPN1-EVI1; Acute Myeloid Leukemia With Multilineage Dysplasia; Acute Myeloid Leukemia With t(6;9); Acute Undifferentiated Leukemia; Adult Acute Lymphoblastic Leukemia in Complete Remission; B Acute Lymphoblastic Leukemia With T(1;19)(Q23;P13.3); E2A-PBX1 (TCF3-PBX1); Ph+ ALL; Burkitt Lymphoma; Childhood Acute Lymphoblastic Leukemia in Complete Remission; DS Stage II Plasma Cell Myeloma; DS Stage III Plasma Cell Myeloma; Myelodysplastic Syndrome; Recurrent Anaplastic Large Cell Lymphoma; Blasts Under 5 Percent of Bone Marrow Nucleated Cells; Recurrent Follicular Lymphoma; Recurrent Hodgkin Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma; Secondary Acute Myeloid Leukemia; T Lymphoblastic Lymphoma; Hematopoietic Cell Transplant Recipient |
Fred Hutchinson Cancer Center |
2010-05-19 | PHASE2 |
| NCT04424602 | COMPLETED | Lupus Nephritis |
Al-Azhar University |
2021-04-05 | PHASE4 |
| NCT00740805 | ACTIVE_NOT_RECRUITING | Ann Arbor Stage III Non-Hodgkin Lymphoma; Ann Arbor Stage IV Non-Hodgkin Lymphoma; Solid Neoplasm |
National Cancer Institute (NCI) |
2008-08-18 | PHASE1 |
| NCT01807182 | COMPLETED | Stage III Cutaneous Melanoma AJCC v7; Stage IIIA Cutaneous Melanoma AJCC v7; Stage IIIB Cutaneous Melanoma AJCC v7; Stage IIIC Cutaneous Melanoma AJCC v7; Stage IV Cutaneous Melanoma AJCC v6 and v7; Metastatic Melanoma |
Fred Hutchinson Cancer Center |
2013-08-20 | PHASE2 |
| NCT03113500 | ACTIVE_NOT_RECRUITING | Adult T-Cell Leukemia/Lymphoma; Anaplastic Large Cell Lymphoma, ALK-Negative; Anaplastic Large Cell Lymphoma, ALK-Positive; Angioimmunoblastic T-Cell Lymphoma; Ann Arbor Stage II Noncutaneous Anaplastic Large Cell Lymphoma; Ann Arbor Stage III Noncutaneous Anaplastic Large Cell Lymphoma; Ann Arbor Stage IV Noncutaneous Anaplastic Large Cell Lymphoma; Enteropathy-Associated T-Cell Lymphoma; Hepatosplenic T-Cell Lymphoma; Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma; Peripheral T-Cell Lymphoma, Not Otherwise Specified |
City of Hope Medical Center |
2017-05-25 | PHASE2 |
| NCT02101853 | ACTIVE_NOT_RECRUITING | Recurrent B Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2014-12-17 | PHASE3 |
| NCT02706405 | TERMINATED | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements; Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma |
Fred Hutchinson Cancer Center |
2016-11-15 | PHASE1 |
| NCT03579888 | TERMINATED | B Acute Lymphoblastic Leukemia With t(v;11q23.3); KMT2A Rearranged; Recurrent B Acute Lymphoblastic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Recurrent Mantle Cell Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Ph-Like Acute Lymphoblastic Leukemia; Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Refractory Mantle Cell Lymphoma; Refractory Non-Hodgkin Lymphoma; Refractory Ph-Like Acute Lymphoblastic Leukemia; Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Refractory Small Lymphocytic Lymphoma |
M.D. Anderson Cancer Center |
2020-06-26 | PHASE1 |
| NCT03518112 | TERMINATED | Philadelphia Chromosome Negative; Recurrent B Acute Lymphoblastic Leukemia; Refractory B Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2018-04-18 | PHASE2 |
| NCT03023046 | COMPLETED | Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma |
University of Washington |
2017-02-23 | PHASE2 |
| NCT04205240 | TERMINATED | Recurrent Plasma Cell Myeloma |
Srinivas Devarakonda |
2020-12-22 | PHASE2 |
| NCT04233476 | COMPLETED | Lung Cancer; Lymph Node Metastasis |
RDO Pharm. |
2019-10-12 | PHASE3 |
| NCT03338972 | COMPLETED | Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
Fred Hutchinson Cancer Center |
2017-11-29 | PHASE1 |
| NCT01864018 | COMPLETED | Amyloidosis; Plasma Cell Myeloma |
Mayo Clinic |
2013-08-20 | PHASE1; PHASE2 |
| NCT02306161 | ACTIVE_NOT_RECRUITING | Metastatic Ewing Sarcoma; Metastatic Malignant Neoplasm in the Bone; Metastatic Malignant Neoplasm in the Bone Marrow; Metastatic Malignant Neoplasm in the Lung; Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone; Peripheral Primitive Neuroectodermal Tumor of Soft Tissues |
National Cancer Institute (NCI) |
2014-12-12 | PHASE3 |
| NCT01979536 | COMPLETED | Anaplastic Large Cell Lymphoma, ALK-Positive; Ann Arbor Stage II Noncutaneous Childhood Anaplastic Large Cell Lymphoma; Ann Arbor Stage III Noncutaneous Childhood Anaplastic Large Cell Lymphoma; Ann Arbor Stage IV Noncutaneous Childhood Anaplastic Large Cell Lymphoma |
National Cancer Institute (NCI) |
2013-11-13 | PHASE2 |
| NCT03742258 | COMPLETED | Diffuse Large B-Cell Lymphoma; Diffuse Large B-Cell Lymphoma Activated B-Cell Type; Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type; Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements; High Grade B-Cell Lymphoma, Not Otherwise Specified; T-Cell/Histiocyte-Rich Large B-Cell Lymphoma |
Northwestern University |
2019-03-13 | PHASE1 |
| NCT02650986 | ACTIVE_NOT_RECRUITING | Advanced Fallopian Tube Carcinoma; Advanced Malignant Solid Neoplasm; Advanced Melanoma; Advanced Ovarian Carcinoma; Advanced Primary Peritoneal Carcinoma; Advanced Synovial Sarcoma; Clinical Stage III Cutaneous Melanoma AJCC v8; Clinical Stage IV Cutaneous Melanoma AJCC v8; Metastatic Fallopian Tube Carcinoma; Metastatic Melanoma; Metastatic Ovarian Carcinoma; Metastatic Primary Peritoneal Carcinoma; Metastatic Synovial Sarcoma; Pathologic Stage III Cutaneous Melanoma AJCC v8; Pathologic Stage IIIA Cutaneous Melanoma AJCC v8; Pathologic Stage IIIB Cutaneous Melanoma AJCC v8; Pathologic Stage IIIC Cutaneous Melanoma AJCC v8; Pathologic Stage IIID Cutaneous Melanoma AJCC v8; Pathologic Stage IV Cutaneous Melanoma AJCC v8; Platinum-Resistant Fallopian Tube Carcinoma; Platinum-Resistant Ovarian Carcinoma; Platinum-Resistant Primary Peritoneal Carcinoma; Stage III Fallopian Tube Cancer AJCC v8; Stage III Ovarian Cancer AJCC v8; Stage III Primary Peritoneal Cancer AJCC v8; Stage IIIA Fallopian Tube Cancer AJCC v8; Stage IIIA Ovarian Cancer AJCC v8; Stage IIIA Primary Peritoneal Cancer AJCC v8; Stage IIIA1 Fallopian Tube Cancer AJCC v8; Stage IIIA1 Ovarian Cancer AJCC v8; Stage IIIA2 Fallopian Tube Cancer AJCC v8; Stage IIIA2 Ovarian Cancer AJCC v8; Stage IIIB Fallopian Tube Cancer AJCC v8; Stage IIIB Ovarian Cancer AJCC v8; Stage IIIB Primary Peritoneal Cancer AJCC v8; Stage IIIC Fallopian Tube Cancer AJCC v8; Stage IIIC Ovarian Cancer AJCC v8; Stage IIIC Primary Peritoneal Cancer AJCC v8; Stage IV Fallopian Tube Cancer AJCC v8; Stage IV Ovarian Cancer AJCC v8; Stage IV Primary Peritoneal Cancer AJCC v8; Stage IVA Fallopian Tube Cancer AJCC v8; Stage IVA Ovarian Cancer AJCC v8; Stage IVA Primary Peritoneal Cancer AJCC v8; Stage IVB Fallopian Tube Cancer AJCC v8; Stage IVB Ovarian Cancer AJCC v8; Stage IVB Primary Peritoneal Cancer AJCC v8; Unresectable Melanoma; Unresectable Ovarian Carcinoma; Unresectable Synovial Sarcoma |
Roswell Park Cancer Institute |
2017-07-14 | PHASE1; PHASE2 |
| NCT02912793 | COMPLETED | Niemann-Pick Disease, Type C1 |
Cyclo Therapeutics, Inc. |
2017-03-20 | PHASE1; PHASE2 |
| NCT04537078 | COMPLETED | Infertility, Female |
El Shatby University Hospital for Obstetrics and Gynecology |
2020-09-01 | PHASE3 |
| NCT02420717 | TERMINATED | Recurrent B Acute Lymphoblastic Leukemia; Recurrent Ph-Like Acute Lymphoblastic Leukemia; Refractory B Acute Lymphoblastic Leukemia; Refractory Ph-Like Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2015-07-15 | PHASE2 |
| NCT02478411 | UNKNOWN | Weakness |
Hospital Son Llatzer |
2015-06 | |
| NCT00477412 | COMPLETED | Mantle Cell Lymphoma |
M.D. Anderson Cancer Center |
2007-04-03 | PHASE1; PHASE2 |
| NCT02757391 | TERMINATED | Colorectal Adenocarcinoma; Metastatic Cholangiocarcinoma; Metastatic Colorectal Carcinoma; Metastatic Digestive System Carcinoma; Metastatic Esophageal Carcinoma; Metastatic Gastric Carcinoma; Metastatic Pancreatic Adenocarcinoma; Stage IV Colorectal Cancer AJCC v7; Stage IV Esophageal Cancer AJCC v7; Stage IV Gastric Cancer AJCC v7; Stage IV Pancreatic Cancer AJCC v6 and v7; Stage IVA Colorectal Cancer AJCC v7; Stage IVB Colorectal Cancer AJCC v7 |
M.D. Anderson Cancer Center |
2019-08-09 | PHASE1 |
| NCT02828358 | COMPLETED | Acute Leukemia of Ambiguous Lineage; B Acute Lymphoblastic Leukemia; Mixed Phenotype Acute Leukemia |
National Cancer Institute (NCI) |
2017-04-01 | PHASE2 |
| NCT02481310 | UNKNOWN | Adult Burkitt Lymphoma; B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma; Diffuse Large B-Cell Lymphoma; MYC Gene Mutation; Plasmablastic Lymphoma |
Northwestern University |
2015-10-28 | PHASE1; PHASE2 |
| NCT03426969 | COMPLETED | Primary Myelofibrosis; Secondary Myelofibrosis |
M.D. Anderson Cancer Center |
2018-01-31 | EARLY_PHASE1 |
| NCT03128359 | COMPLETED | Acute Leukemia; Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Diffuse Large B-Cell Lymphoma; Follicular Lymphoma; Graft Versus Host Disease; Hodgkin Lymphoma; Mantle Cell Lymphoma; Marginal Zone Lymphoma; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes; Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma; Secondary Myelodysplastic Syndrome |
City of Hope Medical Center |
2017-05-30 | PHASE2 |
| NCT02538926 | WITHDRAWN | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Recurrent T Lymphoblastic Leukemia/Lymphoma; Refractory B Lymphoblastic Lymphoma; Refractory T Lymphoblastic Lymphoma; T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
University of Washington |
2018-07-01 | PHASE2 |
| NCT02774291 | TERMINATED | HLA-A2 Positive Cells Present; Metastatic Malignant Neoplasm; Metastatic Malignant Neoplasm in the Brain |
Albert Einstein College of Medicine |
2017-04-20 | EARLY_PHASE1 |
| NCT02408016 | TERMINATED | Advanced Pleural Malignant Mesothelioma; HLA-A*0201 Positive Cells Present; Recurrent Non-Small Cell Lung Carcinoma; Recurrent Pleural Malignant Mesothelioma; Stage III Non-Small Cell Lung Cancer AJCC v7; Stage III Pleural Malignant Mesothelioma AJCC v7; Stage IIIA Non-Small Cell Lung Cancer AJCC v7; Stage IIIB Non-Small Cell Lung Cancer AJCC v7; Stage IV Non-Small Cell Lung Cancer AJCC v7; Stage IV Pleural Malignant Mesothelioma AJCC v7; WT1 Positive |
Fred Hutchinson Cancer Center |
2015-05-22 | PHASE1; PHASE2 |
| NCT03268889 | UNKNOWN | Peripheral T Cell Lymphoma |
The First Affiliated Hospital of Soochow University |
2017-06-15 | |
| NCT01697293 | TERMINATED | Breast Adenocarcinoma; Estrogen Receptor Positive; HER2/Neu Negative; Recurrent Breast Carcinoma; Stage IIB Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer |
Prescient Therapeutics, Ltd. |
2012-01 | PHASE1; PHASE2 |
| NCT03100877 | WITHDRAWN | Plasma Cell Leukemia in Remission; Plasma Cell Myeloma |
City of Hope Medical Center |
2018-01 | PHASE1; PHASE2 |
| NCT03792620 | UNKNOWN | Multiple Myeloma Stage I |
Grupo de Estudos Multicentricos em Onco-Hematologia |
2018-11-20 | PHASE3 |
| NCT04145830 | COMPLETED | Glaucoma Treatment Using Focused Ultrasound |
EyeTechCare |
2019-09-01 | |
| NCT02872792 | TERMINATED | Sepsis |
University Hospital, Rouen |
2016-12-14 | |
| NCT00867178 | COMPLETED | Medulloblastoma; Pineoblastoma; Supratentorial Embryonal Tumor, Not Otherwise Specified |
National Cancer Institute (NCI) |
2009-02-25 | PHASE1 |
| NCT01363128 | COMPLETED | Acute Lymphoblastic Leukemia; Adult Acute Lymphoblastic Leukemia in Complete Remission; Burkitt Leukemia; Burkitt Lymphoma; CD20 Positive; Childhood Acute Lymphoblastic Leukemia in Complete Remission; Lymphoblastic Lymphoma |
M.D. Anderson Cancer Center |
2011-07-12 | PHASE2 |
| NCT03488225 | TERMINATED | Acute Lymphoblastic Leukemia in Remission; B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative |
M.D. Anderson Cancer Center |
2018-03-28 | PHASE2 |
| NCT01231906 | COMPLETED | Localized Extraskeletal Ewing Sarcoma; Peripheral Primitive Neuroectodermal Tumor of Bone; Peripheral Primitive Neuroectodermal Tumor of Soft Tissues |
Children's Oncology Group |
2010-11-24 | PHASE3 |
| NCT02112916 | ACTIVE_NOT_RECRUITING | Adult T Acute Lymphoblastic Leukemia; Ann Arbor Stage II Adult Lymphoblastic Lymphoma; Ann Arbor Stage II Childhood Lymphoblastic Lymphoma; Ann Arbor Stage III Adult Lymphoblastic Lymphoma; Ann Arbor Stage III Childhood Lymphoblastic Lymphoma; Ann Arbor Stage IV Adult Lymphoblastic Lymphoma; Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma; Childhood T Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2014-10-04 | PHASE3 |
| NCT01856192 | ACTIVE_NOT_RECRUITING | Ann Arbor Stage II Diffuse Large B-Cell Lymphoma; Ann Arbor Stage III Diffuse Large B-Cell Lymphoma; Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma |
National Cancer Institute (NCI) |
2013-08-27 | PHASE2 |
| NCT03017131 | ACTIVE_NOT_RECRUITING | Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma |
Roswell Park Cancer Institute |
2017-12-08 | PHASE1 |
| NCT01640301 | TERMINATED | Recurrent Adult Acute Myeloid Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Therapy-Related Acute Myeloid Leukemia; Donor; Hematopoietic Cell Transplant Recipient; HLA-A*0201 Positive Cells Present; Recurrent Acute Myeloid Leukemia |
Fred Hutchinson Cancer Center |
2012-12-06 | PHASE1; PHASE2 |
| NCT04321122 | UNKNOWN | Glaucoma; Glaucoma, Primary Open Angle |
Zhongshan Ophthalmic Center, Sun Yat-sen University |
2018-08-12 | |
| NCT03187418 | COMPLETED | Glaucoma; Glaucoma, Open-Angle; Glaucoma, Neovascular; Glaucoma and Ocular Hypertension; Glaucoma Eye; Glaucoma, Uncompensated; Glaucoma Secondary |
Centre hospitalier de l'Université de Montréal (CHUM) |
2017-06-19 | |
| NCT02939547 | COMPLETED | Niemann-Pick Disease, Type C1 |
Cyclo Therapeutics, Inc. |
2017-10-11 | PHASE1 |
| NCT03440411 | TERMINATED | Multiple Myeloma |
Fondazione EMN Italy Onlus |
2016-02-18 | PHASE3 |
| NCT02561273 | COMPLETED | Anaplastic Large Cell Lymphoma, ALK-Negative; Anaplastic Large Cell Lymphoma, ALK-Positive; Hepatosplenic T-Cell Lymphoma; Peripheral T-Cell Lymphoma, Not Otherwise Specified; Stage II Angioimmunoblastic T-cell Lymphoma; Stage II Enteropathy-Associated T-Cell Lymphoma; Stage III Angioimmunoblastic T-cell Lymphoma; Stage III Enteropathy-Associated T-Cell Lymphoma; Stage IV Angioimmunoblastic T-cell Lymphoma; Stage IV Enteropathy-Associated T-Cell Lymphoma |
University of Nebraska |
2015-09-28 | PHASE1; PHASE2 |
| NCT00392327 | COMPLETED | Anaplastic Medulloblastoma; Medulloblastoma |
Children's Oncology Group |
2007-05-23 | PHASE3 |
| NCT02853318 | COMPLETED | Fallopian Tube Clear Cell Adenocarcinoma; Fallopian Tube Endometrioid Adenocarcinoma; Fallopian Tube Mucinous Adenocarcinoma; Fallopian Tube Serous Adenocarcinoma; Ovarian Clear Cell Adenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Adenocarcinoma; Ovarian Serous Adenocarcinoma; Primary Peritoneal Serous Adenocarcinoma; Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Undifferentiated Fallopian Tube Carcinoma; Undifferentiated Ovarian Carcinoma |
Roswell Park Cancer Institute |
2016-09-01 | PHASE2 |
| NCT03560271 | COMPLETED | Diabetes Mellitus, Type 2 |
NovMetaPharma Co., Ltd. |
2018-06-18 | PHASE2 |
| NCT03303950 | TERMINATED | Anemia; ASXL1 Gene Mutation; EZH2 Gene Mutation; IDH1 Gene Mutation; IDH2 Gene Mutation; Plasma Cell Myeloma; Primary Myelofibrosis; Recurrent Plasma Cell Myeloma; Secondary Myelofibrosis; Thrombocytopenia |
University of Utah |
2018-03-30 | PHASE2 |
| NCT02775292 | COMPLETED | Adult Solid Neoplasm; Childhood Solid Neoplasm; Metastatic Neoplasm |
Jonsson Comprehensive Cancer Center |
2017-01-03 | PHASE1 |
| NCT01190930 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Lymphoblastic Lymphoma; Ann Arbor Stage I B Lymphoblastic Lymphoma; Ann Arbor Stage II B Lymphoblastic Lymphoma; Childhood B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Childhood B Lymphoblastic Lymphoma; Down Syndrome; Hypodiploid B Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive |
Children's Oncology Group |
2010-08-11 | PHASE3 |
| NCT02948101 | WITHDRAWN | Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma |
M.D. Anderson Cancer Center |
2018-12-31 | PHASE2 |
| NCT01570348 | TERMINATED | Crohn Disease |
Fred Hutchinson Cancer Center |
2012-07-17 | PHASE2 |
| NCT01606878 | COMPLETED | Childhood Solid Neoplasm; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Neuroblastoma |
Children's Oncology Group |
2013-04-29 | PHASE1 |
| NCT02541565 | COMPLETED | Composite Lymphoma; Grade 3b Follicular Lymphoma; Stage I Diffuse Large B-Cell Lymphoma; Stage I Follicular Lymphoma; Stage II Diffuse Large B-Cell Lymphoma; Stage II Follicular Lymphoma; Stage III Diffuse Large B-Cell Lymphoma; Stage III Follicular Lymphoma; Stage IV Diffuse Large B-Cell Lymphoma; Stage IV Follicular Lymphoma |
University of Washington |
2015-11-24 | PHASE1 |
| NCT02048813 | ACTIVE_NOT_RECRUITING | Anemia; Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma |
National Cancer Institute (NCI) |
2014-03-10 | PHASE3 |
| NCT00358657 | TERMINATED | Immunodeficiency Syndrome; Severe Aplastic Anemia; Genetic Disorder |
Fred Hutchinson Cancer Center |
2006-05-24 | PHASE2 |
| NCT00723099 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Aggressive Non-Hodgkin Lymphoma; Chronic Myelogenous Leukemia; Chronic Phase Chronic Myelogenous Leukemia; Indolent Non-Hodgkin Lymphoma; Lymphoma; Mixed Phenotype Acute Leukemia; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Recurrent Chronic Lymphocytic Leukemia; Recurrent Follicular Lymphoma; Recurrent Lymphoplasmacytic Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Plasma Cell Myeloma; Recurrent Small Lymphocytic Lymphoma; Recurrent T-Cell Non-Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Chronic Myelogenous Leukemia; Refractory Follicular Lymphoma; Refractory Hodgkin Lymphoma; Refractory Lymphoplasmacytic Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Small Lymphocytic Lymphoma; T-Cell Non-Hodgkin Lymphoma |
Fred Hutchinson Cancer Center |
2008-06-25 | PHASE2 |
| NCT00450814 | COMPLETED | Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
Mayo Clinic |
2006-11-30 | PHASE1; PHASE2 |
| NCT00554788 | COMPLETED | Extraocular Retinoblastoma |
Children's Oncology Group |
2008-05-06 | PHASE3 |
| NCT01008462 | COMPLETED | B-Cell Prolymphocytic Leukemia; Hypodiploidy; Loss of Chromosome 17p; Plasma Cell Leukemia; Progression of Multiple Myeloma or Plasma Cell Leukemia; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Non-Hodgkin Lymphoma; Recurrent Childhood Hodgkin Lymphoma; Recurrent Childhood Non-Hodgkin Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Plasma Cell Myeloma; Recurrent Small Lymphocytic Lymphoma; Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Non-Hodgkin Lymphoma; Refractory Plasma Cell Myeloma; Refractory Small Lymphocytic Lymphoma; t(14;16); t(4;14); T-Cell Prolymphocytic Leukemia; Waldenstrom Macroglobulinemia |
Fred Hutchinson Cancer Center |
2010-03-18 | PHASE2 |
| NCT02907320 | WITHDRAWN | Venous Disease Classification (CEAP): C2 or C3 |
Pierre Fabre Medicament |
2016-12 | PHASE2 |
| NCT01527149 | COMPLETED | Stage I Mantle Cell Lymphoma; Stage II Contiguous Mantle Cell Lymphoma; Stage II Non-Contiguous Mantle Cell Lymphoma; Stage III Mantle Cell Lymphoma; Stage IV Mantle Cell Lymphoma |
Roswell Park Cancer Institute |
2011-12-06 | PHASE2 |
| NCT02779283 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia |
OHSU Knight Cancer Institute |
2016-01-13 | PHASE1 |
| NCT02017964 | COMPLETED | Desmoplastic/Nodular Medulloblastoma; Medulloblastoma; Medulloblastoma With Extensive Nodularity; Nevoid Basal Cell Carcinoma Syndrome |
Children's Oncology Group |
2013-12-24 | PHASE2 |
| NCT01824693 | COMPLETED | Juvenile Myelomonocytic Leukemia |
Children's Oncology Group |
2013-06-24 | PHASE2 |
| NCT01256398 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 |
National Cancer Institute (NCI) |
2010-12-14 | PHASE2 |
| NCT00408005 | COMPLETED | T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
National Cancer Institute (NCI) |
2007-01-30 | PHASE3 |
| NCT00557193 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Undifferentiated Leukemia; Childhood T Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2008-01-15 | PHASE3 |
| NCT02914470 | COMPLETED | Breast Cancer; Cervix Cancer; Ovarian Cancer; Endometrial Cancer |
The Netherlands Cancer Institute |
2017-01 | PHASE1 |
| NCT01275677 | COMPLETED | HER2/Neu Positive; Progesterone Receptor Positive; Recurrent Breast Carcinoma; Stage IA Breast Cancer AJCC v7; Stage IB Breast Cancer AJCC v7; Stage IIA Breast Cancer AJCC v6 and v7; Stage IIB Breast Cancer AJCC v6 and v7; Stage IIIA Breast Cancer AJCC v7; Stage IIIC Breast Cancer AJCC v7 |
National Cancer Institute (NCI) |
2011-02-08 | PHASE3 |
| NCT02784275 | COMPLETED | Diabetes Mellitus Type 2 in Obese |
NovMetaPharma Co., Ltd. |
2016-06-09 | PHASE2 |
| NCT00789776 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Aggressive Non-Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Previously Treated Myelodysplastic Syndrome; Recurrent Chronic Lymphocytic Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Recurrent Indolent Adult Non-Hodgkin Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Plasma Cell Myeloma; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hodgkin Lymphoma; Refractory Plasma Cell Myeloma; Refractory Small Lymphocytic Lymphoma; Waldenstrom Macroglobulinemia |
Fred Hutchinson Cancer Center |
2008-10-13 | PHASE1; PHASE2 |
| NCT00336024 | COMPLETED | Anaplastic Medulloblastoma; Medulloblastoma; Supratentorial Embryonal Tumor, Not Otherwise Specified; Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor |
Children's Oncology Group |
2007-10-22 | PHASE3 |
| NCT01351909 | ACTIVE_NOT_RECRUITING | Locally Advanced Unresectable Breast Carcinoma; Metastatic Breast Carcinoma; Recurrent Breast Carcinoma; Stage IIIB Breast Cancer AJCC v7; Stage IIIC Breast Cancer AJCC v7; Stage IV Breast Cancer AJCC v6 and v7 |
National Cancer Institute (NCI) |
2011-05-02 | PHASE1 |
| NCT01193842 | COMPLETED | AIDS-Related Plasmablastic Lymphoma; AIDS-Related Primary Effusion Lymphoma; Ann Arbor Stage I Diffuse Large B-Cell Lymphoma; Ann Arbor Stage I Grade 3 Follicular Lymphoma; Ann Arbor Stage II Diffuse Large B-Cell Lymphoma; Ann Arbor Stage II Grade 3 Contiguous Follicular Lymphoma; Ann Arbor Stage II Grade 3 Non-Contiguous Follicular Lymphoma; Ann Arbor Stage III Diffuse Large B-Cell Lymphoma; Ann Arbor Stage III Grade 3 Follicular Lymphoma; Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma; Ann Arbor Stage IV Grade 3 Follicular Lymphoma; HIV Infection; Plasmablastic Lymphoma; Primary Effusion Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Grade 3 Follicular Lymphoma |
National Cancer Institute (NCI) |
2010-10-06 | PHASE1; PHASE2 |
| NCT00589316 | TERMINATED | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; CD45-Positive Neoplastic Cells Present; Chronic Myelomonocytic Leukemia; Previously Treated Myelodysplastic Syndrome; Refractory Anemia With Excess Blasts; Refractory Anemia With Ring Sideroblasts; Refractory Cytopenia With Multilineage Dysplasia; Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts |
Fred Hutchinson Cancer Center |
2007-10-05 | PHASE1 |
| NCT01175356 | COMPLETED | Ganglioneuroblastoma; Localized Resectable Neuroblastoma; Localized Unresectable Neuroblastoma; Regional Neuroblastoma; Stage 4 Neuroblastoma; Stage 4S Neuroblastoma |
Children's Oncology Group |
2011-12-21 | PHASE1 |
| NCT00653068 | COMPLETED | Childhood Atypical Teratoid/Rhabdoid Tumor |
Children's Oncology Group |
2009-02-10 | PHASE3 |
| NCT02650635 | TERMINATED | Colorectal Adenocarcinoma; Metastatic Pancreatic Adenocarcinoma; Recurrent Breast Carcinoma; Recurrent Colorectal Carcinoma; Recurrent Melanoma of the Skin; Recurrent Non-Small Cell Lung Carcinoma; Recurrent Pancreatic Carcinoma; Recurrent Renal Cell Carcinoma; Solid Neoplasm; Stage IV Breast Cancer; Stage IV Non-Small Cell Lung Cancer; Stage IV Renal Cell Cancer; Stage IV Skin Melanoma; Stage IVA Colorectal Cancer; Stage IVA Pancreatic Cancer; Stage IVB Colorectal Cancer; Stage IVB Pancreatic Cancer |
Mayo Clinic |
2016-02-05 | PHASE1 |
| NCT00379340 | COMPLETED | Stage III Kidney Wilms Tumor; Stage IV Kidney Wilms Tumor |
Children's Oncology Group |
2007-04-30 | PHASE3 |
| NCT01955434 | COMPLETED | Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
Mayo Clinic |
2013-11 | PHASE2 |
| NCT00792948 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Adult L1 Acute Lymphoblastic Leukemia; Adult L2 Acute Lymphoblastic Leukemia; Adult T Acute Lymphoblastic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2009-09-01 | PHASE2 |
| NCT01055314 | COMPLETED | Adult Rhabdomyosarcoma; Childhood Alveolar Rhabdomyosarcoma; Childhood Embryonal Rhabdomyosarcoma; Metastatic Childhood Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma; Untreated Childhood Rhabdomyosarcoma |
National Cancer Institute (NCI) |
2010-01 | PHASE2 |
| NCT00822120 | COMPLETED | Lymphoma; Nonneoplastic Condition |
SWOG Cancer Research Network |
2009-07 | PHASE2 |
| NCT01689987 | COMPLETED | Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
OHSU Knight Cancer Institute |
2012-09 | PHASE1 |
| NCT00085735 | COMPLETED | Medulloblastoma |
Children's Oncology Group |
2004-04-30 | PHASE3 |
| NCT00005803 | COMPLETED | Prolymphocytic Leukemia; Recurrent Adult Hodgkin Lymphoma; Recurrent Childhood Hodgkin Lymphoma; Recurrent Childhood Non-Hodgkin Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Non-Hodgkin Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hodgkin Lymphoma; Refractory Non-Hodgkin Lymphoma; Refractory Small Lymphocytic Lymphoma; T-Cell Chronic Lymphocytic Leukemia; T-Cell Prolymphocytic Leukemia |
Fred Hutchinson Cancer Center |
1999-09 | PHASE1; PHASE2 |
| NCT00972478 | ACTIVE_NOT_RECRUITING | Ann Arbor Stage II Non-Hodgkin Lymphoma; Ann Arbor Stage III Non-Hodgkin Lymphoma; Ann Arbor Stage IV Non-Hodgkin Lymphoma |
National Cancer Institute (NCI) |
2010-11-15 | PHASE1; PHASE2 |
| NCT01798004 | COMPLETED | Ganglioneuroblastoma; Stage 1 Neuroblastoma; Stage 2 Neuroblastoma; Stage 2A Neuroblastoma; Stage 2B Neuroblastoma; Stage 3 Neuroblastoma; Stage 4 Neuroblastoma; Stage 4S Neuroblastoma |
Children's Oncology Group |
2013-04-09 | PHASE1 |
| NCT00107198 | COMPLETED | Ann Arbor Stage I Childhood Hodgkin Lymphoma; Ann Arbor Stage II Childhood Hodgkin Lymphoma; Childhood Nodular Lymphocyte Predominant B-Cell Lymphoma |
Children's Oncology Group |
2006-03-10 | PHASE2 |
| NCT01222715 | COMPLETED | Adult Rhabdomyosarcoma; Childhood Alveolar Rhabdomyosarcoma; Childhood Pleomorphic Rhabdomyosarcoma; Childhood Rhabdomyosarcoma With Mixed Embryonal and Alveolar Features; Previously Treated Childhood Rhabdomyosarcoma; Recurrent Adult Soft Tissue Sarcoma; Recurrent Childhood Rhabdomyosarcoma |
National Cancer Institute (NCI) |
2010-10 | PHASE2 |
| NCT00567567 | COMPLETED | Localized Resectable Neuroblastoma; Localized Unresectable Neuroblastoma; Recurrent Neuroblastoma; Regional Neuroblastoma; Stage 4 Neuroblastoma; Stage 4S Neuroblastoma |
Children's Oncology Group |
2007-11-05 | PHASE3 |
| NCT00354835 | COMPLETED | Adult Rhabdomyosarcoma; Childhood Alveolar Rhabdomyosarcoma; Childhood Botryoid-Type Embryonal Rhabdomyosarcoma; Childhood Embryonal Rhabdomyosarcoma; Localized Childhood Soft Tissue Sarcoma; Rhabdomyosarcoma; Sarcoma; Stage I Adult Soft Tissue Sarcoma AJCC v7; Stage II Adult Soft Tissue Sarcoma AJCC v7; Stage III Adult Soft Tissue Sarcoma AJCC v7 |
Children's Oncology Group |
2006-12-26 | PHASE3 |
| NCT00720109 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 |
National Cancer Institute (NCI) |
2008-07-14 | PHASE2; PHASE3 |
| NCT00602459 | COMPLETED | Stage I Chronic Lymphocytic Leukemia; Stage II Chronic Lymphocytic Leukemia; Stage III Chronic Lymphocytic Leukemia; Stage IV Chronic Lymphocytic Leukemia |
National Cancer Institute (NCI) |
2008-01-15 | PHASE2 |
| NCT00209222 | UNKNOWN | Lymphoma, Mantle-Cell |
European Mantle Cell Lymphoma Network |
2004-07 | PHASE3 |
| NCT01606241 | COMPLETED | Recurrent Breast Carcinoma; Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma; Stage IIA Breast Cancer; Stage IIA Fallopian Tube Cancer; Stage IIA Ovarian Cancer; Stage IIB Breast Cancer; Stage IIB Fallopian Tube Cancer; Stage IIB Ovarian Cancer; Stage IIC Fallopian Tube Cancer; Stage IIC Ovarian Cancer; Stage IIIA Breast Cancer; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Cancer; Stage IIIA Primary Peritoneal Cancer; Stage IIIB Breast Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Cancer; Stage IIIB Primary Peritoneal Cancer; Stage IIIC Breast Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Cancer; Stage IIIC Primary Peritoneal Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Primary Peritoneal Cancer |
Mayo Clinic |
2012-07-24 | PHASE1 |
| NCT00861705 | COMPLETED | Male Breast Carcinoma; Stage IIA Breast Cancer AJCC v6 and v7; Stage IIB Breast Cancer AJCC v6 and v7; Stage IIIA Breast Cancer AJCC v7; Triple-Negative Breast Carcinoma |
National Cancer Institute (NCI) |
2009-07-21 | PHASE2 |
| NCT00866307 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2009-02-23 | PHASE1 |
| NCT01592955 | COMPLETED | Glaucoma |
EyeTechCare |
2012-05 | PHASE4 |
| NCT00433511 | ACTIVE_NOT_RECRUITING | Breast Adenocarcinoma |
National Cancer Institute (NCI) |
2007-11-02 | PHASE3 |
| NCT00103285 | COMPLETED | Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2005-04-11 | PHASE3 |
| NCT00033293 | COMPLETED | Localized Resectable Neuroblastoma; Localized Unresectable Neuroblastoma; Regional Neuroblastoma; Stage 4 Neuroblastoma; Stage 4S Neuroblastoma |
Children's Oncology Group |
2004-03-15 | PHASE3 |
| NCT00878605 | TERMINATED | Diabetes |
VA Office of Research and Development |
2010-04-01 | PHASE2 |
| NCT00453388 | COMPLETED | Acute Myeloid Leukemia in Remission; de Novo Myelodysplastic Syndrome; Fanconi Anemia; Previously Treated Myelodysplastic Syndrome |
Fred Hutchinson Cancer Center |
2007-02 | PHASE2 |
| NCT01024010 | COMPLETED | Chronic Lymphocytic Leukemia; Stage 0 Chronic Lymphocytic Leukemia; Stage I Chronic Lymphocytic Leukemia; Stage I Small Lymphocytic Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Small Lymphocytic Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Small Lymphocytic Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Small Lymphocytic Lymphoma |
Mayo Clinic |
2010-03 | PHASE2 |
| NCT00025259 | COMPLETED | Childhood Lymphocyte-Depleted Classical Hodgkin Lymphoma; Childhood Mixed Cellularity Classical Hodgkin Lymphoma; Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma; Childhood Nodular Sclerosis Classical Hodgkin Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage II Childhood Hodgkin Lymphoma; Stage III Childhood Hodgkin Lymphoma; Stage IV Childhood Hodgkin Lymphoma |
Children's Oncology Group |
2002-09 | PHASE3 |
| NCT00513292 | COMPLETED | HER2/Neu Positive; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer |
National Cancer Institute (NCI) |
2007-07 | PHASE3 |
| NCT01055301 | WITHDRAWN | Multiple Myeloma; Plasma Cell Myeloma |
SWOG Cancer Research Network |
2011-07 | PHASE2 |
| NCT00671034 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2008-07-21 | PHASE3 |
| NCT00075725 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2003-12-29 | PHASE3 |
| NCT00052936 | COMPLETED | Lymphoma |
German High-Grade Non-Hodgkin's Lymphoma Study Group |
2001-01 | PHASE3 |
| NCT01220297 | TERMINATED | Hematologic Diseases; Acute-graft-versus-host Disease; Leukemia; Non-Hodgkin Lymphoma (NHL); Hodgkin Lymphoma |
Stanford University |
2006-08 | PHASE2 |
| NCT01076556 | TERMINATED | Chronic Lymphocytic Leukemia; Prolymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Stage I Chronic Lymphocytic Leukemia; Stage I Small Lymphocytic Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Small Lymphocytic Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Small Lymphocytic Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Small Lymphocytic Lymphoma |
National Cancer Institute (NCI) |
2010-04 | PHASE1 |
| NCT00626626 | TERMINATED | Leukemia; Myelodysplastic Syndrome; Chronic Myelogenous Leukemia; Lymphoma; Hodgkin's Lymphoma; Multiple Myeloma |
Milton S. Hershey Medical Center |
2007-05 | PHASE1; PHASE2 |
| NCT00551265 | WITHDRAWN | Fallopian Tube Carcinoma; Primary Peritoneal Carcinoma; Recurrent Ovarian Carcinoma; Stage III Ovarian Cancer; Stage IV Ovarian Cancer |
Gynecologic Oncology Group |
2007-10 | |
| NCT00072566 | COMPLETED | Primary Peritoneal Carcinoma; Recurrent Ovarian Carcinoma; Stage IV Ovarian Cancer |
National Cancer Institute (NCI) |
2003-12 | PHASE2 |
| NCT00004031 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
1997-07 | PHASE3 |
| NCT00079261 | COMPLETED | Lymphoma; Small Intestine Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2004-01 | PHASE2 |
| NCT00002565 | COMPLETED | Lymphoma |
M.D. Anderson Cancer Center |
1994-05-25 | PHASE3 |
| NCT00003541 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1998-06 | PHASE1; PHASE2 |
| NCT00003595 | COMPLETED | Lymphoma |
National Cancer Institute (NCI) |
1999-01 | PHASE3 |
| NCT00005970 | COMPLETED | Breast Adenocarcinoma; HER2 Positive Breast Carcinoma; Stage IA Breast Cancer AJCC v7; Stage IB Breast Cancer AJCC v7; Stage IIA Breast Cancer AJCC v6 and v7; Stage IIB Breast Cancer AJCC v6 and v7; Stage IIIA Breast Cancer AJCC v7 |
National Cancer Institute (NCI) |
2000-05-19 | PHASE3 |
| NCT00060385 | TERMINATED | Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
2003-03 | PHASE2; PHASE3 |
| NCT00004179 | COMPLETED | Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1999-05 | PHASE3 |
| NCT00003215 | COMPLETED | Lymphoma |
Swiss Cancer Institute |
1997-04 | PHASE3 |
| NCT00002548 | COMPLETED | Multiple Myeloma |
SWOG Cancer Research Network |
1994-01 | PHASE3 |
| NCT00072007 | COMPLETED | Leukemia |
Swiss Cancer Institute |
2002-06 | PHASE2 |
| NCT00003784 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
1999-05 | PHASE2 |
| NCT00004221 | TERMINATED | Malignant Ovarian Mixed Epithelial Tumor; Ovarian Clear Cell Cystadenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Cystadenocarcinoma; Ovarian Serous Cystadenocarcinoma; Primary Peritoneal Carcinoma; Stage III Ovarian Cancer; Undifferentiated Ovarian Carcinoma |
Gynecologic Oncology Group |
1999-11 | PHASE2 |
| NCT00004112 | COMPLETED | Lymphoma |
University of Nebraska |
1999-09-01 | PHASE3 |
| NCT00905073 | COMPLETED | Type 1 Diabetes Mellitus |
Georgetown University |
1990-02 | |
| NCT00003578 | UNKNOWN | Lymphoma |
Lymphoma Trials Office |
1993-01 | PHASE3 |
| NCT00005867 | COMPLETED | Lymphoma |
Lymphoma Trials Office |
1998-01 | PHASE3 |
| NCT00159159 | UNKNOWN | Cardiac Transplantion |
Hospices Civils de Lyon |
2004-03 | PHASE4 |
| NCT00003150 | COMPLETED | Lymphoma |
Eastern Cooperative Oncology Group |
1997-12 | PHASE3 |
(data from https://clinicaltrials.gov, updated on 2026-08-05)
Check the
Cyclo(-RGDfK) TFA
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
Note: Technical data last updated: Sep 1, 2026.