CAS No. 100-88-9
Batch:
Purity:100
Chemical Structure
Check the
Cyclamic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 100-88-9 | |
|---|---|---|
| Molecular Formula |
C6H13NO3S
|
|
| Molecular Weight (MW) | 179.24 | |
| SMILES | C1CCC(CC1)NS(=O)(=O)O |
Biological Activity
Cyclamic acid is a synthetic sweetening agent that functions as an agonist of the human sweet taste receptor complex TAS1R2/TAS1R3. Upon binding to the transmembrane domain of the TAS1R3 subunit, cyclamic acid activates G protein-coupled receptor signaling in taste receptor cells. This activation induces intracellular calcium mobilization and depolarizes gustatory neurons, ultimately transmitting sweet taste perception signals to the central nervous system.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
36 mg/mL
(200.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 36 mg/mL |
| Ethanol | 36 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
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Note: Technical data last updated: Sep 1, 2026.