How to Prepare Stock Solution?

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Check the Pelabresib (CPI-0610) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 73 mg/mL (199.55 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 73 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Storage

Form Storage Temp Shelf Life
Powder -20°C 3 years
In Solvent -80°C 1 year
In Solvent -20°C 1 month

Working Concentrations

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Note: Technical data last updated: Sep 1, 2026.