CAS No. 24729-96-2

Batch: Purity:98.82
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Clindamycin Phosphate Chemical Structure
Chemical Structure
Check the Clindamycin Phosphate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 24729-96-2
Molecular Formula

C18H34ClN2O8PS
Molecular Weight (MW) 504.96
SMILES CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)OP(=O)(O)O)O)O)C(C)Cl

Ordering Information

Biological Activity

Clindamycin Phosphate is a lincosamide antibiotic that exhibits potent antimalarial activity against Plasmodium falciparum. It targets the apicoplast 50S ribosomal subunit to disrupt protein synthesis within the parasite. This inhibition impairs apicoplast function, leading to delayed death phenotype and eventual parasite clearance, rendering it a valuable tool for cell signaling and antiparasitic research. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 101 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.