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For research use only. Not for use in humans.

Cixutumumab (Anti-IGF1R / CD221)

Synonyms: IMC-A12

Cixutumumab (Anti-IGF1R / CD221) is a humanized monoclonal antibody with high affinity that targets type-1-insulin-like growth factor receptor (IGF-1R).It shows broad-spectrum anti-tumour activity and can be used in studies of sarcomas, neuroblastoma, wilms tumor, lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer. MW :150 KD.

Cixutumumab (Anti-IGF1R / CD221)

Quality Control

  • Cited in Nature Medicine for its top-tier quality
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  • Datasheet

Mechanism of Action

Description
Cixutumumab (Anti-IGF1R / CD221) is a humanized monoclonal antibody with high affinity that targets type-1-insulin-like growth factor receptor (IGF-1R).It shows broad-spectrum anti-tumour activity and can be used in studies of sarcomas, neuroblastoma, wilms tumor, lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer. MW :150 KD.
References

Product Details

CAS No. 947687-12-9
Molecular Weight 150
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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