cis-Resveratrol Clinical Trials

Size	Price	Qty
5mg	USD 147
25mg	USD 329

Clinical Trials

Multiple clinical trials are currently actively recruiting participants to evaluate interventions for psychological distress and esophageal cancer. Sponsored by academic and medical institutions, including Universidad de las Americas - Quito and Erasmus Medical Center, these studies focus on routine outcome monitoring in psychotherapy and active surveillance following neoadjuvant chemoradiation. These ongoing research efforts across mental health and oncological indications currently have no specified phase designations.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT05343741	Recruiting	Psychological Distress	Universidad de las Americas - Quito	2022-10-17	--
NCT04886635	Recruiting	Cancer of Esophagus	Bas P. L. Wijnhoven\|Erasmus Medical Center	2021-03-09	--

(data from https://clinicaltrials.gov, updated on 2024-05-22)

Check the cis-Resveratrol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

cis-Resveratrol modulates key signaling targets including cyclooxygenase, lipoxygenase, and sirtuin pathways, thereby inhibiting pro-inflammatory mediator production, dampening downstream biochemical cascades, and driving cellular apoptosis. By suppressing proliferation and inducing programmed cell death through these molecular targets, this compound demonstrates anti-neoplastic activity pertinent to clinical study in esophageal cancer.

Appendix RUO and cGMP Quality Standards

Quality Dimension	RUO (Research Use Only)	cGMP (Current Good Manufacturing Practice)
Clinical Applicability	Prohibited in human clinical trials or medical diagnostics.	Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status	Non-regulated grade; exempt from drug manufacturing laws.	Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment	Unclassified analytical or research laboratories.	Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control	Basic purity and activity testing.	Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation	Basic equipment calibration; no process validation required.	Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance	Vendor self-declared without required formal QMS.	Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact	High risk of IND rejection if used as a critical raw material.	Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).