SMILES:

O.O.NC1=NC(=O)N(CC(CO)OC[P;v5](O)(O)=O)C=C1
Cidofovir hydrate Chemical Structure
Chemical Structure
Check the Cidofovir hydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid;dihydrate
CAS Number 149394-66-1
Molecular Formula

C8H14N3O6P.2H2O
Molecular Weight (MW) 315.22
SMILES O.O.NC1=NC(=O)N(CC(CO)OC[P;v5](O)(O)=O)C=C1
InChIKey FPKARFMSZDBYQF-ILKKLZGPSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 4 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.