CAS No. 638156-11-3

Batch: Purity:98.99
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CID 2011756 Chemical Structure
Chemical Structure
Check the CID 2011756 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 5-(3-chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide
CAS Number 638156-11-3
Molecular Formula

C22H21ClN2O3
Molecular Weight (MW) 396.87
SMILES C1COCCN1CC2=CC=C(C=C2)NC(=O)C3=CC=C(O3)C4=CC(=CC=C4)Cl
InChIKey XQJWTJLJEYIUDZ-UHFFFAOYSA-N

Biological Activity

CID 2011756 is a small-molecule inhibitor of protein kinase D (PKD), targeting PKD1 (IC50 3.2 μM), PKD2 (IC50 0.6 μM), and PKD3 (IC50 0.7 μM). By inhibiting PKD phosphorylation and activity, CID 2011756 disrupts downstream signaling pathways regulating cell survival and motility. Consequently, it suppresses prostate cancer cell proliferation and inhibits cell migration in vitro.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 30 mg/mL (75.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.