CAS No. 3858-89-7

Batch: Purity:99.93
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Chloroprocaine HCl Chemical Structure
Chemical Structure
Check the Chloroprocaine HCl product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-(diethylamino)ethyl 4-amino-2-chlorobenzoate;hydrochloride
CAS Number 3858-89-7
Molecular Formula

C13H20Cl2N2O2
Molecular Weight (MW) 307.22
SMILES CCN(CC)CCOC(=O)C1=C(C=C(C=C1)N)Cl.Cl
InChIKey SZKQYDBPUCZLRX-UHFFFAOYSA-N

Ordering Information

Biological Activity

Chloroprocaine HCl is an ester-type local anesthetic that functions as a voltage-gated sodium channel inhibitor. By binding to voltage-gated sodium channels within neuronal membranes, it reversibly blocks sodium ion influx during membrane depolarization. This inhibition prevents the generation and conduction of action potentials along nerve fibers, thereby disrupting cellular depolarization and suppressing downstream neuronal signal propagation.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 61 mg/mL (198.55 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 61 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.