CAS No. 35607-66-0
Batch:
Purity:99.96
Chemical Structure
Check the
Cefoxitin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 35607-66-0 | |
|---|---|---|
| Molecular Formula |
C16H17N3O7S2 |
|
| Molecular Weight (MW) | 427.45 | |
| SMILES | COC1(C2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)O)NC(=O)CC3=CC=CS3 |
Cefoxitin is a second-generation cephamycin beta-lactam antibiotic that targets penicillin-binding proteins (PBPs) involved in bacterial cell wall synthesis. By binding to essential PBPs, Cefoxitin inhibits peptidoglycan transpeptidase activity, weakening cell wall cross-linking and disrupting structural integrity, which leads to cell lysis and potent bactericidal activity against a broad spectrum of Gram-positive and Gram-negative bacteria. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
85 mg/mL
(198.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 2 mg/mL |
| Water | Insoluble |
| DMSO |
85 mg/mL
(198.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 85 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.