CAS No. 79350-37-1

Batch: Purity:99.71
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Cefixime Chemical Structure
Chemical Structure
Check the Cefixime product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(carboxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number 79350-37-1
Molecular Formula

C16H15N5O7S2
Molecular Weight (MW) 453.45
SMILES C=CC1=C(N2C(C(C2=O)NC(=O)C(=NOCC(=O)O)C3=CSC(=N3)N)SC1)C(=O)O
InChIKey OKBVVJOGVLARMR-QSWIMTSFSA-N

Ordering Information

Biological Activity

Cefixime is an orally active, third-generation cephalosporin antibiotic that targets penicillin-binding proteins (PBPs). By binding to and inhibiting specific PBPs involved in peptidoglycan synthesis, cefixime disrupts bacterial cell wall assembly. This inhibition leads to cell wall degradation and ultimately causes osmotic lysis and bacterial cell death in susceptible Gram-positive and Gram-negative bacteria. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 90 mg/mL (198.47 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 1 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.