CAS No. 402939-18-8

Batch: Purity:99.55
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1-Cyclohexyl-3-dodecyl urea Chemical Structure
Chemical Structure
Check the 1-Cyclohexyl-3-dodecyl urea product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 1-cyclohexyl-3-dodecylurea
CAS Number 402939-18-8
Molecular Formula

C19H38N2O
Molecular Weight (MW) 310.52
SMILES CCCCCCCCCCCCNC(=O)NC1CCCCC1
InChIKey POEWFBSYPFIYSK-UHFFFAOYSA-N

Biological Activity

1-Cyclohexyl-3-dodecyl urea is a selective inhibitor of soluble epoxide hydrolase (sEH). By blocking sEH-mediated hydrolysis, it prevents the conversion of bioactive epoxyeicosatrienoic acids (EETs) into dihydroxyeicosatrienoic acids (DHETs), thereby elevating endogenous EET levels. Increased EET accumulation modulates arachidonic acid cascade pathways to promote anti-inflammatory and vasodilatory responses, supporting vascular and cardiovascular homeostasis.

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Ethanol 30 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.