CAS No. 285986-88-1
Batch:
Purity:99.98
Chemical Structure
Check the
CCG-1423
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide | |
|---|---|---|
| CAS Number | 285986-88-1 | |
| Molecular Formula |
C18H13ClF6N2O3 |
|
| Molecular Weight (MW) | 454.75 | |
| SMILES | CC(C(=O)NC1=CC=C(C=C1)Cl)ONC(=O)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F | |
| InChIKey | DSMXVSGJIDFLKP-UHFFFAOYSA-N |
CCG-1423 is a RhoA pathway inhibitor that suppresses serum response factor (SRF)-mediated gene transcription. By targeting the Rho signaling network, CCG-1423 blocks MRTF/SRF-dependent transcriptional activation and disrupts downstream gene expression involved in actin cytoskeletal dynamics. Consequently, this inhibition reduces cell motility and suppresses cancer cell proliferation, migration, and invasion in cellular models. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
90 mg/mL
(197.91 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.