CBL0137 Hydrochloride IC50 for Cell-based and Cell-free Assays

CBL0137 Hydrochloride is a potent FACT complex inhibitor. It affects NF-κB, p53, and MYC signaling pathways by trapping the FACT complex into chromatin, inducing Z-DNA formation, and disrupting homologous recombination, thereby inhibiting tumor cell proliferation and promoting apoptosis and immunogenic cell death.

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