CAS No. 499-75-2
Batch:
Purity:99.87
Chemical Structure
Check the
Carvacrol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 2-methyl-5-propan-2-ylphenol | |
|---|---|---|
| CAS Number | 499-75-2 | |
| Molecular Formula |
C10H14O |
|
| Molecular Weight (MW) | 150.22 | |
| InChIKey | RECUKUPTGUEGMW-UHFFFAOYSA-N |
Biological Activity
Carvacrol is a monoterpenic phenol compound that acts as a natural activator of peroxisome proliferator-activated receptors alpha and gamma (PPARα and PPARγ) and an inhibitor of acetylcholinesterase. Activation of PPAR signaling leads to the suppression of cyclooxygenase-2 (COX-2) expression and inhibition of NF-kB signaling pathways. These downstream effects contribute to reduced inflammatory responses, suppressed cell proliferation, and decreased oxidative stress across various cellular models. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
30 mg/mL
(199.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 30 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.