CAS No. 77-23-6

Batch: Purity:
Carbetapentane Chemical Structure
Chemical Structure
Check the Carbetapentane product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 77-23-6
Molecular Formula

C20H31NO3

Molecular Weight (MW) 333.46
SMILES CCN(CC)CCOCCOC(=O)C1(CCCC1)C2=CC=CC=C2

Ordering Information

Biological Activity

Carbetapentane (pentoxyverine) is a non-opioid, nonselective sigma-1 receptor agonist that exhibits potent antitussive and anticonvulsant properties. Activation of sigma-1 receptors by carbetapentane modulates central neurotransmitter pathways and regulates neuronal calcium homeostasis, resulting in reduced neuronal hyperexcitability. Downstream, these pharmacological actions lead to the suppression of cough reflex pathways and the inhibition of convulsive seizure responses in animal models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.