Target Selectivity of AZD5363 (Capivasertib)

Key TargetIC50DescriptionReference
AKT1 3 nM in vitro potency measurement PMC12990551
AKT3 3 nM in vitro potency measurement PMC12990551
AKT2 9 nM in vitro potency measurement PMC12990551
AKT isoforms 10 nM -- PMC4658545
AKT 1 10 nM Enzyme inhibition assay PMC5613074
Check the AZD5363 (Capivasertib) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

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