Capecitabine: Mechanism of Action

Capecitabine MOA:Targeting Thymidylate Synthase/DNA Synthesis Pathway for Breast Cancer

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Capecitabine is a prodrug-type DNA synthesis inhibitor. It affects ERS/ROS/mitochondrial and ferroptosis signaling pathways. By metabolizing into 5-FU to disrupt DNA metabolism and induce oxidative stress, it inhibits tumor cell proliferation and promotes apoptosis.

Primary Applications and Mechanism of Action