For research use only. Not for use in humans.

Cantuzumab ravtansine

Synonyms: IMGN242, huC242-DM4 Cat.No.D4032

Cantuzumab ravtansine (IMGN242, HUC242-DM4) is an ADC. It is a humanized monoclonal antibody, huC242, covalently linked via a disulfide bond to DM4. Cantuzumab ravtansine has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts.

CAS No. 868747-45-9

Quality Control

Cited in Nature Medicine for its top-tier quality
SDS
Datasheet

Mechanism of Action

Description	Cantuzumab ravtansine (IMGN242, HUC242-DM4) is an ADC. It is a humanized monoclonal antibody, huC242, covalently linked via a disulfide bond to DM4. Cantuzumab ravtansine has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts.
References	[1] https://aacrjournals.org/cancerres/article/65/9_Supplement/334/519750/ [2] https://aacrjournals.org/mct/article/6/11_Supplement/A127/236941

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	868747-45-9
ADC antiody	Cantuzumab
ADC cytotoxin	DM4
Formulation	1xPBS
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.