CAS No. 163706-36-3
Batch:
Purity:99.98
Chemical Structure
Check the
Cangrelor Tetrasodium
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | tetrasodium;[dichloro(phosphonato)methyl]-[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-oxidophosphoryl]oxyphosphinate | |
|---|---|---|
| CAS Number | 163706-36-3 | |
| Molecular Formula |
21Cl2F3N5O12P3S2.4Na |
|
| Molecular Weight (MW) | 864.29 | |
| SMILES | CSCCNC1=C2C(=NC(=N1)SCCC(F)(F)F)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)(C(P(=O)([O-])[O-])(Cl)Cl)[O-])O)O.[Na+].[Na+].[Na+].[Na+] | |
| InChIKey | COWWROCHWNGJHQ-OPKBHZIBSA-J |
Cangrelor Tetrasodium (AR-C69931MX) is a potent, competitive inhibitor of the purinergic P2Y12 receptor. By selectively binding to the platelet P2Y12 receptor, it blocks adenosine diphosphate-mediated signaling pathways and inhibits downstream intracellular activation processes. Consequently, this targeted antagonism blocks granule secretion and shape change, leading to rapid and reversible suppression of ADP-induced platelet aggregation. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 100 mg/mL |
| DMSO |
2 mg/mL
(2.31 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
| Water | 100 mg/mL |
| DMSO |
70 mg/mL
(80.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | Insoluble |
| Water | 100 mg/mL |
| DMSO |
20 mg/mL
(23.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(115.7 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Cangrelor Tetrasodium Clinical Trials
- Cangrelor Tetrasodium Solubility in DMSO
- Cangrelor Tetrasodium Stock Solution
- Cangrelor Tetrasodium Storage
- Cangrelor Tetrasodium Stability
- Cangrelor Tetrasodium Molecular Weight
- Cangrelor Tetrasodium SMILES
- Cangrelor Tetrasodium Chemical Structure (2D and 3D)
- Cangrelor Tetrasodium SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.