- Inhibitors
- Antibodies
- Compound Libraries
- New Products
- Contact Us
Synonyms: SHR-1210
Camrelizumab (anti-PD-1) is a humanized anti-PD-1 IgG4 antibody that blocks the binding of PD-L1 and PD-L2 to PD-1 with immune checkpoint inhibitory and antineoplastic activities, MW: 146.3 KD.
Shimon Sakaguchi
Nature Communications 2025,16, Article number:1325
David Baker
Dev Cell 2023, 58(20):2163-2180.e9.
David Julius
Cell 2017, 185-198.e16
Michael Houghton
Cell Chem Biol, 2020, 27(7):780-792.e5
Charles M. Rice
Cell 2018, 172(3):423-438.e25
| Name | Citation | PD-1/PD-L1 interaction | PD-1 | PD-L1 | PD-1/PD-L1 | Others |
|---|---|---|---|---|---|---|
| GS-4224 | 0 | |||||
| INCB086550 | 1 | |||||
| BMS-1001 | 0 | |||||
| BMS-1166 | 8 | |||||
| PD-1/PD-L1 Inhibitor 3 | 13 | |||||
| BMS-1 | 13 | |||||
| BMS202 | 26 | |||||
| CA-170 (AUPM-170) | 0 | |||||
| SR 0987 | 1 | IL17,RORγt | ||||
| Spartalizumab (anti-PD-1) | 3 | |||||
| Camrelizumab (anti-PD-1) | 2 | |||||
| AUNP-12 | 3 |
| Description |
Camrelizumab (anti-PD-1) is a humanized anti-PD-1 IgG4 antibody that blocks the binding of PD-L1 and PD-L2 to PD-1 with immune checkpoint inhibitory and antineoplastic activities, MW: 146.3 KD.
|
|---|---|
| Features |
Human IgG4
|
| Targets/IC50/Ki |
PD-1
|
References |
| CAS No. | 1798286-48-2 |
|---|---|
| Isotype | Human IgG4 |
| Source | CHO cells |
| Sterility | 0.2 μM filtered |
| Formulation | PBS buffer, pH 7.2 |
| Storage (From the date of receipt) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.
Question 1:
How to store the antibody?
Answer:
Store the undiluted solution at 4 °C in the dark. Freezing antibodies can result in a loss of activity caused by the freezing/thawing process. Diluting antibodies to working concentrations and storing at 4°C for more than a day should be avoided. Additionally, make sure to keep the antibody sterile. Under these storage conditions, your antibodies should remain active for up to one year and oftentimes longer.