GSK1265744 (Cabotegravir) is a potent HIV-1 integrase strand transfer inhibitor. It affects HIV-1 replication pathways by binding to the integrase catalytic domain and blocking the strand transfer step, effectively inhibiting viral DNA integration and HIV-1 infection.
GSK1265744 (Cabotegravir) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for GSK1265744 (Cabotegravir) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.