CAS No. 218137-86-1
| IUPAC Name | 4-methylidene-2-octyl-5-oxooxolane-3-carboxylic acid | |
|---|---|---|
| CAS Number | 218137-86-1 | |
| Molecular Formula |
C14H22O4 |
|
| Molecular Weight (MW) | 254.32 | |
| SMILES | CCCCCCCCC1OC(=O)C(=C)C1C(O)=O | |
| InChIKey | VCWLZDVWHQVAJU-UHFFFAOYSA-N |
C75 is a synthetic fatty acid synthase (FAS) inhibitor and carnitine palmitoyltransferase-1 (CPT1) activator. By inhibiting de novo lipid biosynthesis and enhancing fatty acid oxidation, C75 alters cellular lipid metabolism, causes malonyl-CoA accumulation, and induces apoptosis in various cancer models. Additionally, C75 acts centrally and peripherally to suppress food intake and stimulate energy expenditure, resulting in weight loss in preclinical animal models. [1]
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Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
51 mg/mL
(200.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 51 mg/mL |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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