CAS No. 38396-39-3
Batch:
Purity:99.64
Chemical Structure
Check the
Bupivacaine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 38396-39-3 | |
|---|---|---|
| Molecular Formula |
C18H28N2O |
|
| Molecular Weight (MW) | 288.43 |
Bupivacaine is a local anesthetic compound and voltage-gated sodium channel blocker. It significantly reduces cell viability and induces apoptosis through the mitochondrial pathway. In neuronal cells, bupivacaine stimulates the generation of reactive oxygen species and activates the MAPK and NF-κB signaling pathways, leading to altered expression of downstream stress-response genes and cytotoxicity. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
58 mg/mL
(201.08 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 58 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.